{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:53:26Z","timestamp":1762300406781,"version":"build-2065373602"},"reference-count":27,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"am","delay-in-days":254,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["annalsofvascularsurgery.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Vascular Surgery"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.avsg.2025.07.028","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T15:12:27Z","timestamp":1753283547000},"page":"383-390","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Osteopenia is a Risk Factor for 2-year Postoperative Survival in Patients with Chronic Limb-Threatening Ischemia"],"prefix":"10.1016","volume":"121","author":[{"given":"Go","family":"Kinoshita","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9187-8403","authenticated-orcid":false,"given":"Yutaka","family":"Matsubara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohei","family":"Ueno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Fujioka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinichiro","family":"Yoshino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koichi","family":"Morisaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Furuyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihiro","family":"Onohara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoharu","family":"Yoshizumi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.avsg.2025.07.028_bib1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2019.05.006","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"58","author":"Conte","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib2","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.jvs.2014.10.094","article-title":"Sarcopenia is a prognostic factor for overall survival in patients with critical limb ischemia","volume":"61","author":"Matsubara","year":"2015","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib3","doi-asserted-by":"crossref","first-page":"1390","DOI":"10.1016\/j.jvs.2016.09.030","article-title":"Sarcopenia is a risk factor for cardiovascular events experienced by patients with critical limb ischemia","volume":"65","author":"Matsubara","year":"2017","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib4","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCINTERVENTIONS.118.006778","article-title":"Impact of frailty on clinical outcomes in patients with critical limb ischemia","volume":"11","author":"Takeji","year":"2018","journal-title":"Circ Cardiovasc Interv"},{"key":"10.1016\/j.avsg.2025.07.028_bib5","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1016\/j.jvs.2017.04.048","article-title":"Influence of frailty on treatment outcomes after revascularization in patients with critical limb ischemia","volume":"66","author":"Morisaki","year":"2017","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib6","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1093\/ageing\/afq034","article-title":"Sarcopenia: European consensus on definition and diagnosis: report of the European working group on sarcopenia in older people","volume":"39","author":"Cruz-Jentoft","year":"2010","journal-title":"Age Ageing"},{"key":"10.1016\/j.avsg.2025.07.028_bib7","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1007\/s00595-018-1697-9","article-title":"High intramuscular adipose tissue content as a precondition of sarcopenia in patients with aortic aneurysm","volume":"48","author":"Matsubara","year":"2018","journal-title":"Surg Today"},{"key":"10.1016\/j.avsg.2025.07.028_bib8","doi-asserted-by":"crossref","first-page":"6465","DOI":"10.21873\/anticanres.13009","article-title":"Impact of osteopenia in liver cirrhosis: special reference to standard bone mineral density with age","volume":"38","author":"Toshima","year":"2018","journal-title":"Anticancer Res"},{"key":"10.1016\/j.avsg.2025.07.028_bib9","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/cam4.4416","article-title":"Osteopenia is associated with wasting in pancreatic adenocarcinoma and predicts survival after surgery","volume":"11","author":"Cameron","year":"2022","journal-title":"Cancer Med"},{"key":"10.1016\/j.avsg.2025.07.028_bib10","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.3390\/curroncol30020144","article-title":"Osteopenia is associated with shorter survival in patients with intrahepatic cholangiocarcinoma","volume":"30","author":"Miki","year":"2023","journal-title":"Curr Oncol"},{"key":"10.1016\/j.avsg.2025.07.028_bib11","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1002\/jbmr.389","article-title":"Relationships between calcified atherosclerotic plaque and bone mineral density in African Americans with type 2 diabetes","volume":"26","author":"Divers","year":"2011","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.avsg.2025.07.028_bib12","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1007\/s00595-022-02550-3","article-title":"Osteosarcopenia predicts poor prognosis for patients with intrahepatic cholangiocarcinoma after hepatic resection","volume":"53","author":"Taniai","year":"2023","journal-title":"Surg Today"},{"key":"10.1016\/j.avsg.2025.07.028_bib13","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1093\/hmg\/11.15.1775","article-title":"Osteopenia and male-specific sudden cardiac death in mice lacking a zinc transporter gene, Znt5","volume":"11","author":"Inoue","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.avsg.2025.07.028_bib14","first-page":"19","article-title":"The link between osteoporosis and cardiovascular disease","volume":"5","author":"Farhat","year":"2008","journal-title":"Clin Cases Miner Bone Metab"},{"key":"10.1016\/j.avsg.2025.07.028_bib15","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/1045098","article-title":"Bone mineral density as a predictor of atherogenic indexes of cardiovascular disease, especially in nonobese adults","volume":"2019","author":"Chuang","year":"2019","journal-title":"Dis Markers"},{"key":"10.1016\/j.avsg.2025.07.028_bib16","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1038\/s41574-021-00555-5","article-title":"Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus","volume":"17","author":"Khosla","year":"2021","journal-title":"Nat Rev Endocrinol"},{"key":"10.1016\/j.avsg.2025.07.028_bib17","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1007\/s00198-007-0338-8","article-title":"The association of bone mineral density measures with incident cardiovascular disease in older adults","volume":"18","author":"Farhat","year":"2007","journal-title":"Osteoporos Int"},{"key":"10.1016\/j.avsg.2025.07.028_bib18","article-title":"Osteoporosis is associated with high risk for coronary heart disease","volume":"94","author":"Chen","year":"2015","journal-title":"Medicine"},{"key":"10.1016\/j.avsg.2025.07.028_bib19","doi-asserted-by":"crossref","first-page":"1800","DOI":"10.1161\/CIRCULATIONAHA.109.859595","article-title":"CC chemokine receptor-1 activates intimal smooth muscle-like cells in graft arterial disease","volume":"12018","author":"Shimizu","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.avsg.2025.07.028_bib20","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.jvs.2013.08.003","article-title":"The society for vascular surgery lower extremity threatened limb classification system: risk stratification based on Wound, Ischemia, and foot Infection (WIfI)","volume":"591","author":"Mills","year":"2014","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib21","doi-asserted-by":"crossref","first-page":"209","DOI":"10.11138\/ccmbm\/2017.14.1.209","article-title":"Oxidative stress in bone remodeling: role of antioxidants","volume":"14","author":"Domazetovic","year":"2017","journal-title":"Clin Cases Miner Bone Metab"},{"key":"10.1016\/j.avsg.2025.07.028_bib22","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.maturitas.2020.05.020","article-title":"Calcium, vitamin D, vitamin K2, and magnesium supplementation and skeletal health","volume":"140","author":"Capozzi","year":"2020","journal-title":"Maturitas"},{"key":"10.1016\/j.avsg.2025.07.028_bib23","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1111\/os.13009","article-title":"Comprehensive interventions including vitamin D effectively reduce the risk of falls in elderly osteoporotic patients","volume":"13","author":"Feng","year":"2021","journal-title":"Orthop Surg"},{"key":"10.1016\/j.avsg.2025.07.028_bib24","doi-asserted-by":"crossref","first-page":"450","DOI":"10.3109\/s10165-012-0678-x","article-title":"Clinical results of alendronate monotherapy and combined therapy with menatetrenone (VitK2) in postmenopausal RA patients","volume":"23","author":"Suzuki","year":"2013","journal-title":"Mod Rheumatol"},{"key":"10.1016\/j.avsg.2025.07.028_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2021.116233","article-title":"Impact of magnesium on bone health in older adults: a systematic review and meta-analysis","volume":"154","author":"Groenendijk","year":"2022","journal-title":"Bone"},{"key":"10.1016\/j.avsg.2025.07.028_bib26","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1111\/jocn.16537","article-title":"Implications for long COVID: a systematic review and meta-aggregation of experience of patients diagnosed with COVID-19","volume":"33","author":"Zheng","year":"2024","journal-title":"J Clin Nurs"},{"key":"10.1016\/j.avsg.2025.07.028_bib27","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1002\/jbmr.3284","article-title":"High-intensity resistance and impact training improves bone mineral density and physical function in postmenopausal women with osteopenia and osteoporosis: the LIFTMOR randomized controlled trial","volume":"33","author":"Watson","year":"2018","journal-title":"J Bone Miner Res"}],"container-title":["Annals of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890509625005059?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0890509625005059?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,4]],"date-time":"2025-11-04T23:47:15Z","timestamp":1762300035000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0890509625005059"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":27,"alternative-id":["S0890509625005059"],"URL":"https:\/\/doi.org\/10.1016\/j.avsg.2025.07.028","relation":{},"ISSN":["0890-5096"],"issn-type":[{"type":"print","value":"0890-5096"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Osteopenia is a Risk Factor for 2-year Postoperative Survival in Patients with Chronic Limb-Threatening Ischemia","name":"articletitle","label":"Article Title"},{"value":"Annals of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.avsg.2025.07.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}