{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T15:15:55Z","timestamp":1783350955904,"version":"3.54.6"},"reference-count":19,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001030","name":"National Heart Foundation of Australia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001030","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100016058","name":"Townsville Hospital and Health Service","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100016058","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003550","name":"Queensland Government","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003550","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["GNT2041176 \/ GNT2026319 \/ GNT1180736"],"award-info":[{"award-number":["GNT2041176 \/ GNT2026319 \/ GNT1180736"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100025520","name":"Medical Research Future Fund","doi-asserted-by":"publisher","award":["MRF2032898 \/ MRF2022807 \/ MRF2015979 \/ MRF2015817 \/ MRF2015999"],"award-info":[{"award-number":["MRF2032898 \/ MRF2022807 \/ MRF2015979 \/ MRF2015817 \/ MRF2015999"]}],"id":[{"id":"10.13039\/501100025520","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["annalsofvascularsurgery.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Annals of Vascular Surgery"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.avsg.2026.03.060","type":"journal-article","created":{"date-parts":[[2026,5,6]],"date-time":"2026-05-06T23:06:10Z","timestamp":1778108770000},"page":"308-318","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Comparing BEST-CLI Participants with Patients Treated at a Tertiary Center Serving a Regional-Remote Population"],"prefix":"10.1016","volume":"130","author":[{"given":"Shivshankar","family":"Thanigaimani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oh Sung","family":"Choy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5779-8848","authenticated-orcid":false,"given":"Jonathan","family":"Golledge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.avsg.2026.03.060_bib1","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ejvs.2019.05.006","article-title":"Global vascular guidelines on the management of chronic limb-threatening ischemia","volume":"58","author":"Conte","year":"2019","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.avsg.2026.03.060_bib2","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.1056\/NEJMoa2207899","article-title":"Surgery or endovascular therapy for chronic limb-threatening ischemia","volume":"387","author":"Farber","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.avsg.2026.03.060_bib3","doi-asserted-by":"crossref","first-page":"883","DOI":"10.4239\/wjd.v12.i6.883","article-title":"Control of modifiable risk factors and major adverse cardiovascular events in people with peripheral artery disease and diabetes","volume":"12","author":"Golledge","year":"2021","journal-title":"World J Diabetes"},{"key":"10.1016\/j.avsg.2026.03.060_bib4","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.jvs.2010.08.077","article-title":"Socioeconomic and hospital-related predictors of amputation for critical limb ischemia","volume":"53","author":"Henry","year":"2011","journal-title":"J Vasc Surg"},{"key":"10.1016\/j.avsg.2026.03.060_bib5","first-page":"MR000045","article-title":"Factors that impact on recruitment to randomised trials in health care: a qualitative evidence synthesis","volume":"10","author":"Houghton","year":"2020","journal-title":"Cochrane Database Syst Rev"},{"key":"10.1016\/j.avsg.2026.03.060_bib6","doi-asserted-by":"crossref","first-page":"e463","DOI":"10.1161\/CIRCULATIONAHA.106.174526","volume":"113","author":"Hirsch","year":"2006","journal-title":"Circulation"},{"key":"10.1016\/j.avsg.2026.03.060_bib7","first-page":"E212","article-title":"Peripheral arterial calcification: prevalence, mechanism, detection, and clinical implications","volume":"83","author":"Rocha-Singh","year":"2014","journal-title":"Catheter Cardiovasc Interv"},{"key":"10.1016\/j.avsg.2026.03.060_bib8","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.118.010748","article-title":"Cohort study examining the association between blood pressure and cardiovascular events in patients with Peripheral Artery Disease","volume":"8","author":"Thomas Manapurathe","year":"2019","journal-title":"J Am Heart Assoc"},{"key":"10.1016\/j.avsg.2026.03.060_bib9","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.atherosclerosis.2013.11.034","article-title":"Association of Chronic Kidney Disease categories defined with different formulae with major adverse events in patients with Peripheral Vascular Disease","volume":"232","author":"Golledge","year":"2014","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.avsg.2026.03.060_bib11","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0241802","article-title":"Survival following abdominal aortic aneurysm repair in North Queensland is not associated with remoteness of place of residence","volume":"15","author":"Golledge","year":"2020","journal-title":"PLoS One"},{"key":"10.1016\/j.avsg.2026.03.060_bib12","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.avsg.2021.07.010","article-title":"Cohort study examining the association of immunosuppressant drug prescription with major adverse cardiovascular and limb events in patients with peripheral artery disease","volume":"78","author":"Golledge","year":"2022","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.avsg.2026.03.060_bib13","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1016\/j.ejvs.2024.07.041","article-title":"Editor's choice \u2013 major adverse limb events in patients undergoing revascularisation for lower limb peripheral arterial disease: a nationwide observational study","volume":"68","author":"Amlani","year":"2024","journal-title":"Eur J Vasc Endovasc Surg"},{"key":"10.1016\/j.avsg.2026.03.060_bib14","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1016\/S0895-4356(96)00236-3","article-title":"A simulation study of the number of events per variable in logistic regression analysis","volume":"49","author":"Peduzzi","year":"1996","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.avsg.2026.03.060_bib15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.avsg.2023.12.100","article-title":"Common criticisms and rebuttals of the best endovascular versus best surgical therapy in patients with chronic limb-threatening ischemia (BEST-CLI) trial","volume":"107","author":"D'Angelo","year":"2024","journal-title":"Ann Vasc Surg"},{"key":"10.1016\/j.avsg.2026.03.060_bib16","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0140-6736(17)32409-1","article-title":"Rivaroxaban with or without aspirin in patients with stable peripheral or carotid artery disease: an international, randomised, double-blind, placebo-controlled trial","volume":"391","author":"Anand","year":"2018","journal-title":"Lancet"},{"key":"10.1016\/j.avsg.2026.03.060_bib17","first-page":"1027","article-title":"Rationale, design and baseline characteristics of participants in the cardiovascular outcomes for people using anticoagulation strategies (COMPASS) trial","volume":"33","author":"Bosch","year":"2017","journal-title":"Can J Cardiol"},{"key":"10.1016\/j.avsg.2026.03.060_bib18","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.jclinepi.2009.01.012","article-title":"Explanatory and pragmatic attitudes in therapeutical trials","volume":"62","author":"Schwartz","year":"2009","journal-title":"J Clin Epidemiol"},{"key":"10.1016\/j.avsg.2026.03.060_bib19","doi-asserted-by":"crossref","DOI":"10.1136\/bmj.h2147","article-title":"The PRECIS-2 tool: designing trials that are fit for purpose","volume":"350","author":"Loudon","year":"2015","journal-title":"BMJ"},{"key":"10.1016\/j.avsg.2026.03.060_bib20","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1177\/1740774515598334","article-title":"Exploring the ethical and regulatory issues in pragmatic clinical trials","volume":"12","author":"Califf","year":"2015","journal-title":"Clin Trials"}],"container-title":["Annals of Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089050962600275X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S089050962600275X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T14:36:05Z","timestamp":1783348565000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S089050962600275X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":19,"alternative-id":["S089050962600275X"],"URL":"https:\/\/doi.org\/10.1016\/j.avsg.2026.03.060","relation":{},"ISSN":["0890-5096"],"issn-type":[{"value":"0890-5096","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Comparing BEST-CLI Participants with Patients Treated at a Tertiary Center Serving a Regional-Remote Population","name":"articletitle","label":"Article Title"},{"value":"Annals of Vascular Surgery","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.avsg.2026.03.060","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}