{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:19:04Z","timestamp":1789201144914,"version":"build-2803163510"},"reference-count":64,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T00:00:00Z","timestamp":1380585600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Cognition"],"published-print":{"date-parts":[[2013,10]]},"DOI":"10.1016\/j.bandc.2013.07.004","type":"journal-article","created":{"date-parts":[[2013,8,9]],"date-time":"2013-08-09T19:03:51Z","timestamp":1376075031000},"page":"80-91","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":63,"title":["Functional and connectivity changes during working memory in Huntington\u2019s disease: 18 month longitudinal data from the IMAGE-HD study"],"prefix":"10.1016","volume":"83","author":[{"given":"Nellie","family":"Georgiou-Karistianis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Govinda R.","family":"Poudel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan F.","family":"Dom\u00ednguez D","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Langmaid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcus A.","family":"Gray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Churchyard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phyllis","family":"Chua","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth","family":"Borowsky","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary F.","family":"Egan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie C.","family":"Stout","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bandc.2013.07.004_b0005","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1006\/nimg.2000.0582","article-title":"Voxel-based morphometry\u2014The methods","volume":"11","author":"Ashburner","year":"2000","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0010","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/j.neuroimage.2005.02.018","article-title":"Unified segmentation","volume":"26","author":"Ashburner","year":"2005","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0015","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.brainresbull.2006.10.028","article-title":"Change in MRI striatal volumes as a biomarker in preclinical Huntington\u2019s disease","volume":"72","author":"Aylward","year":"2007","journal-title":"Brain Research Bulletin"},{"key":"10.1016\/j.bandc.2013.07.004_b0020","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1136\/jnnp.2010.208264","article-title":"Longitudinal change in regional brain volumes in prodromal Huntington disease","volume":"82","author":"Aylward","year":"2011","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.bandc.2013.07.004_b0025","series-title":"Manual for the beck depression inventory-II","author":"Beck","year":"1996"},{"key":"10.1016\/j.bandc.2013.07.004_b0030","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.brainresrev.2008.04.001","article-title":"Magnetic resonance imaging as an approach towards identifying neuropathological biomarkers for Huntington\u2019s disease","volume":"58","author":"Bohanna","year":"2008","journal-title":"Brain Research Reviews"},{"key":"10.1016\/j.bandc.2013.07.004_b0035","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1089\/ars.2006.8.2061","article-title":"Oxidative damage in Huntington\u2019s disease pathogenesis","volume":"8","author":"Browne","year":"2006","journal-title":"Antioxidants & Redox Signaling"},{"key":"10.1016\/j.bandc.2013.07.004_b0040","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1038\/nrn3214","article-title":"The economy of brain network organization","volume":"13","author":"Bullmore","year":"2012","journal-title":"Nature Reviews Neuroscience"},{"key":"10.1016\/j.bandc.2013.07.004_b0045","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1176\/appi.ajp.160.4.709","article-title":"Abnormal fMRI response of the dorsolateral prefrontal cortex in cognitively intact siblings of patients with schizophrenia","volume":"160","author":"Callicott","year":"2003","journal-title":"American Journal of Psychiatry"},{"key":"10.1016\/j.bandc.2013.07.004_b0050","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1288\/00005537-198402000-00004","article-title":"University of pennsylvania smell identification test: A rapid quantitative olfactory function test for the clinic","volume":"94","author":"Doty","year":"1984","journal-title":"Laryngoscope"},{"key":"10.1016\/j.bandc.2013.07.004_b0055","doi-asserted-by":"crossref","first-page":"2375","DOI":"10.1093\/brain\/awm184","article-title":"Anatomically related grey and white matter abnormalities in adolescent-onset schizophrenia","volume":"130","author":"Douaud","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b0060","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/ana.20684","article-title":"Preclinical Huntington\u2019s disease: Compensatory brain responses during learning","volume":"59","author":"Feigin","year":"2006","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0065","first-page":"1591","article-title":"Metabolic network abnormalities in early Huntington\u2019s disease: An [18F]FDG PET study","volume":"42","author":"Feigin","year":"2001","journal-title":"Journal of Nuclear Medicine"},{"key":"10.1016\/j.bandc.2013.07.004_b0070","doi-asserted-by":"crossref","first-page":"2858","DOI":"10.1093\/brain\/awm217","article-title":"Thalamic metabolism and symptom onset in preclinical Huntington\u2019s disease","volume":"130","author":"Feigin","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b0075","doi-asserted-by":"crossref","first-page":"1040","DOI":"10.1002\/hbm.20446","article-title":"Functional connectivity estimation in fMRI data: Influence of preprocessing and time course selection","volume":"29","author":"Gavrilescu","year":"2008","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.bandc.2013.07.004_b0080","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.expneurol.2009.08.001","article-title":"A peek inside the Huntington\u2019s brain: Will functional imaging take us one step closer in solving the puzzle?","volume":"220","author":"Georgiou-Karistianis","year":"2009","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0090","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.nbd.2012.10.001","article-title":"Automated differentiation of pre-diagnosis Huntington\u2019s disease from healthy control individuals based on quadratic discriminant analysis of the basal ganglia: The IMAGE-HD study","volume":"51","author":"Georgiou-Karistianis","year":"2013","journal-title":"Neurobiology of Disease"},{"key":"10.1016\/j.bandc.2013.07.004_b5090","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.neubiorev.2013.01.022","article-title":"Structural MRI in Huntington's disease and recommendations for its potential use in clinical trials","volume":"37","author":"Georgiou-Karistianis","year":"2013","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.bandc.2013.07.004_b0095","doi-asserted-by":"crossref","first-page":"1791","DOI":"10.1016\/j.neuropsychologia.2006.12.023","article-title":"Increased cortical recruitment in Huntington\u2019s disease using a Simon task","volume":"45","author":"Georgiou-Karistianis","year":"2007","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.bandc.2013.07.004_b0085","doi-asserted-by":"crossref","unstructured":"Georgiou-Karistianis, N., Stout, J.C., Dom\u00ednguez D, J.F., Carron, S.P., Ando, A., Churchyard, A., et al. (2013). Functional magnetic resonance imaging of working memory in Huntington\u2019s disease: Cross-sectional data from the IMAGE-HD study. Human Brain Mapping. (in press).","DOI":"10.1002\/hbm.22296"},{"key":"10.1016\/j.bandc.2013.07.004_b0100","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1006\/nimg.2001.0786","article-title":"A voxel-based morphometric study of ageing in 465 normal adult human brains","volume":"14","author":"Good","year":"2001","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0105","series-title":"Frontal systems behavior scale: Professional manual","author":"Grace","year":"2001"},{"key":"10.1016\/j.bandc.2013.07.004_b0110","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/j.expneurol.2012.10.020","article-title":"Prefrontal activity in Huntington\u2019s disease reflects cognitive and neuropsychiatric disturbances: The IMAGE-HD study","volume":"239","author":"Gray","year":"2013","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0115","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1037\/0033-2909.96.3.573","article-title":"Nonparametric estimators of effect size in meta-analysis","volume":"96","author":"Hedges","year":"1984","journal-title":"Psychological Bulletin"},{"key":"10.1016\/j.bandc.2013.07.004_b0120","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1017\/S1355617707070671","article-title":"Motor timing variability increases in preclinical Huntington\u2019s disease patients as estimated onset of motor symptoms approaches","volume":"13","author":"Hinton","year":"2007","journal-title":"Journal of the International Neuropsychological Society"},{"key":"10.1016\/j.bandc.2013.07.004_b8120","doi-asserted-by":"crossref","first-page":"1659","DOI":"10.1016\/j.neuroimage.2009.06.003","article-title":"Automated quantification of caudate atrophy by local registration of serial MRI: Evaluation and application in Huntington's disease","volume":"47","author":"Hobbs","year":"2009","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0125","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1093\/brain\/awm275","article-title":"White matter connections reflect changes in voluntary-guided saccades in pre-symptomatic Huntington\u2019s disease","volume":"131","author":"Kl\u00f6ppel","year":"2008","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b0130","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.1093\/brain\/awp081","article-title":"Functional compensation of motor function in pre-symptomatic Huntington\u2019s disease","volume":"132","author":"Kl\u00f6ppel","year":"2009","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b0135","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1111\/j.1399-0004.2004.00241.x","article-title":"A new model for prediction of the age of onset and penetrance for Huntington\u2019s disease based on CAG length","volume":"65","author":"Langbehn","year":"2004","journal-title":"Clinical Genetics"},{"key":"10.1016\/j.bandc.2013.07.004_b0140","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1093\/brain\/119.5.1633","article-title":"Executive and mnemonic functions in early Huntington\u2019s disease","volume":"119","author":"Lawrence","year":"1996","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b0145","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00415-004-0461-9","article-title":"Cognitive changes in patients with Huntington\u2019s disease (HD) and asymptomatic carriers of the HD mutation: A longitudinal follow-up study","volume":"251","author":"Lemiere","year":"2004","journal-title":"Journal of Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0150","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1016\/j.neuroimage.2005.07.005","article-title":"Non-white noise in fMRI: Does modelling have an impact?","volume":"29","author":"Lund","year":"2006","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0155","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/0092-8674(93)90585-E","article-title":"A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington\u2019s disease chromosomes","volume":"72","author":"MacDonald","year":"1993","journal-title":"Cell"},{"key":"10.1016\/j.bandc.2013.07.004_b0160","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1139\/jpn.0603","article-title":"Brain imaging and cognitive dysfunctions in Huntington\u2019s disease","volume":"31","author":"Montoya","year":"2006","journal-title":"Journal of Psychiatry and Neuroscience"},{"key":"10.1016\/j.bandc.2013.07.004_b0165","first-page":"533","article-title":"National adult reading test","volume":"7, 2nd ed.","author":"Nelson","year":"1992","journal-title":"International Journal of Geriatric Psychiatry"},{"key":"10.1016\/j.bandc.2013.07.004_b0170","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: The Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.bandc.2013.07.004_b0175","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.expneurol.2008.12.015","article-title":"Functional imaging in Huntington\u2019s disease","volume":"216","author":"Paulsen","year":"2009","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0180","first-page":"1715","article-title":"FMRI biomarker of early neuronal dysfunction in presymptomatic Huntington\u2019s disease","volume":"25","author":"Paulsen","year":"2004","journal-title":"American Journal of Neuroradiology"},{"key":"10.1016\/j.bandc.2013.07.004_b0185","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1002\/ana.410410521","article-title":"CAG repeat number governs the development rate of pathology in Huntington\u2019s disease","volume":"41","author":"Penney","year":"1997","journal-title":"Annals of Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0190","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1002\/mds.20979","article-title":"Diffusion tensor imaging in presymptomatic and early Huntington\u2019s disease: Selective white matter pathology and its relationship to clinical measures","volume":"21","author":"Rosas","year":"2006","journal-title":"Movement Disorders"},{"key":"10.1016\/j.bandc.2013.07.004_b0195","first-page":"1","article-title":"Huntington\u2019s disease and striatal signaling","volume":"6","author":"Roze","year":"2011","journal-title":"Frontiers in Neuroanatomy"},{"key":"10.1016\/j.bandc.2013.07.004_b0200","doi-asserted-by":"crossref","first-page":"2452","DOI":"10.1016\/j.neuroimage.2011.08.105","article-title":"Stability of resting fMRI interregional correlations analyzed in subject-native space: A 1-year longitudinal study in healthy adults and premanifest Huntington\u2019s disease","volume":"59","author":"Seibert","year":"2012","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0205","series-title":"Symbol digit modality test (SDMT): Manual (revised)","author":"Smith","year":"1982"},{"key":"10.1016\/j.bandc.2013.07.004_b0210","doi-asserted-by":"crossref","first-page":"S208","DOI":"10.1016\/j.neuroimage.2004.07.051","article-title":"Advances in functional and structural MR image analysis and implementation as FSL","volume":"23","author":"Smith","year":"2004","journal-title":"NeuroImage"},{"key":"10.1016\/j.bandc.2013.07.004_b0215","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1136\/jnnp.2007.142786","article-title":"A longitudinal diffusion tensor imaging study in symptomatic Huntington\u2019s disease","volume":"81","author":"Sritharan","year":"2010","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.bandc.2013.07.004_b0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1037\/a0020937","article-title":"Neurocognitive Signs in Prodromal Huntington Disease","volume":"25","author":"Stout","year":"2011","journal-title":"Neuropsychology"},{"key":"10.1016\/j.bandc.2013.07.004_b0225","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1037\/h0054651","article-title":"Studies of interference in serial verbal reactions","volume":"18","author":"Stroop","year":"1935","journal-title":"Journal of Experimental Psychology"},{"key":"10.1016\/j.bandc.2013.07.004_b0230","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/S1474-4422(09)70170-X","article-title":"Biological and clinical manifestations of Huntington\u2019s disease in the longitudinal TRACK-HD study: Cross-sectional analysis of baseline data","volume":"8","author":"Tabrizi","year":"2009","journal-title":"The Lancet Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0235","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/S1474-4422(11)70263-0","article-title":"Potential endpoints for clinical trials in premanifest and early Huntington\u2019s disease in the TRACK-HD study: Analysis of 24month observational data","volume":"11","author":"Tabrizi","year":"2012","journal-title":"The Lancet Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0240","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S1474-4422(10)70276-3","article-title":"Biological and clinical changes in premanifest and early stage Huntington\u2019s disease in the TRACK-HD study: The 12-month longitudinal analysis","volume":"10","author":"Tabrizi","year":"2011","journal-title":"The Lancet Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0245","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1136\/jnnp.2006.098368","article-title":"Functional connectivity of the prefrontal cortex in Huntington\u2019s disease","volume":"78","author":"Thiruvady","year":"2007","journal-title":"Journal of Neurology, Neurosurgery and Psychiatry"},{"key":"10.1016\/j.bandc.2013.07.004_b0250","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.neulet.2012.02.095","article-title":"Impaired cortico-striatal functional connectivity in prodromal Huntington\u2019s disease","volume":"514","author":"Unschuld","year":"2012","journal-title":"Neuroscience Letters"},{"key":"10.1016\/j.bandc.2013.07.004_b0255","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1177\/1073191104271483","article-title":"Development and validation of the schedule of compulsions, obsessions, and pathological impulses (SCOPI)","volume":"12","author":"Watson","year":"2005","journal-title":"Assessment"},{"key":"10.1016\/j.bandc.2013.07.004_b0260","doi-asserted-by":"crossref","first-page":"1908","DOI":"10.1038\/jcbfm.2011.60","article-title":"Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington\u2019s disease","volume":"31","author":"Wolf","year":"2011","journal-title":"Journal of Cerebral Blood Flow and Metabolism"},{"key":"10.1016\/j.bandc.2013.07.004_b0265","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1002\/hbm.21348","article-title":"Brain activation and functional connectivity in premanifest Huntington\u2019s disease during states of intrinsic and phasic alertness","volume":"33","author":"Wolf","year":"2012","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.bandc.2013.07.004_b0270","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.expneurol.2008.05.017","article-title":"Aberrant connectivity of lateral prefrontal networks in presymptomatic Huntington\u2019s disease","volume":"213","author":"Wolf","year":"2008","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0275","doi-asserted-by":"crossref","first-page":"1180","DOI":"10.1111\/j.1468-1331.2008.02253.x","article-title":"Altered frontostriatal coupling in pre-manifest Huntington\u2019s disease: Effects of increasing cognitive load","volume":"15","author":"Wolf","year":"2008","journal-title":"European Journal of Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0280","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.expneurol.2011.06.011","article-title":"Longitudinal functional magnetic resonance imaging of cognition in preclinical Huntington\u2019s disease","volume":"231","author":"Wolf","year":"2011","journal-title":"Experimental Neurology"},{"key":"10.1016\/j.bandc.2013.07.004_b0285","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1002\/hbm.20502","article-title":"Cortical dysfunction in patients with Huntington\u2019s disease during working memory performance","volume":"30","author":"Wolf","year":"2009","journal-title":"Human Brain Mapping"},{"key":"10.1016\/j.bandc.2013.07.004_b0290","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1007\/s00115-007-2390-1","article-title":"Functional imaging of cognitive processes in Huntington\u2019s disease and its presymptomatic mutation carriers","volume":"79","author":"Wolf","year":"2008","journal-title":"Nervenarzt"},{"key":"10.1016\/j.bandc.2013.07.004_b0295","doi-asserted-by":"crossref","first-page":"2845","DOI":"10.1093\/brain\/awm210","article-title":"Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington\u2019s disease: Evidence from event-related fMRI","volume":"130","author":"Wolf","year":"2007","journal-title":"Brain"},{"key":"10.1016\/j.bandc.2013.07.004_b9295","doi-asserted-by":"crossref","first-page":"2193","DOI":"10.1523\/JNEUROSCI.23-06-02193.2003","article-title":"Mutant huntingtin causes context-dependent neurodegeneration in mice with Huntington's disease","volume":"23","author":"Yu","year":"2003","journal-title":"J Neurosci"},{"key":"10.1016\/j.bandc.2013.07.004_b0300","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","article-title":"The hospital anxiety and depression scale","volume":"67","author":"Zigmond","year":"1983","journal-title":"Acta Psychiatrica Scandinavica"},{"key":"10.1016\/j.bandc.2013.07.004_b0305","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1017\/S1355617707071214","article-title":"FMRI detection of early neural dysfunction in preclinical Huntington\u2019s disease","volume":"13","author":"Zimbelman","year":"2007","journal-title":"Journal of the International Neuropsychological Society"}],"container-title":["Brain and Cognition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278262613001000?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0278262613001000?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T17:33:02Z","timestamp":1759512782000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0278262613001000"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10]]},"references-count":64,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013,10]]}},"alternative-id":["S0278262613001000"],"URL":"https:\/\/doi.org\/10.1016\/j.bandc.2013.07.004","relation":{},"ISSN":["0278-2626"],"issn-type":[{"value":"0278-2626","type":"print"}],"subject":[],"published":{"date-parts":[[2013,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Functional andconnectivity changes during working memory inHuntington\u2019s disease: 18month longitudinal data from the IMAGE-HD study","name":"articletitle","label":"Article Title"},{"value":"Brain and Cognition","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bandc.2013.07.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}