{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T16:38:45Z","timestamp":1776184725035,"version":"3.50.1"},"reference-count":14,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,16]],"date-time":"2022-01-16T00:00:00Z","timestamp":1642291200000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Spine"],"published-print":{"date-parts":[[2022]]},"DOI":"10.1016\/j.bas.2022.100863","type":"journal-article","created":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T14:28:44Z","timestamp":1642602524000},"page":"100863","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["Impact of brain biopsy on management of nonneoplastic brain disease"],"prefix":"10.1016","volume":"2","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0022-2362","authenticated-orcid":false,"given":"M\u00f3nica","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Roque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexandre","family":"Rainha Campos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu\u00edsa","family":"Albuquerque","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9","family":"Pimentel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bas.2022.100863_bib1","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.jocn.2016.11.013","article-title":"Long-term utility and complication profile of open craniotomy for biopsy in patients with idiopathic encephalitis","volume":"37","author":"Abdullah","year":"2017","journal-title":"J.\u00a0Clin. Neurosci. : Off. J. Neurosurg. Soc. Australasia"},{"issue":"10","key":"10.1016\/j.bas.2022.100863_bib2","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/hiv.12646","article-title":"The role of brain biopsy in the clinical management of HIV-related focal brain lesions","volume":"19","author":"Acosta","year":"2018","journal-title":"HIV Med."},{"issue":"2","key":"10.1016\/j.bas.2022.100863_bib3","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1227\/NEU.0000000000000756","article-title":"Diagnostic value and safety of brain biopsy in patients with cryptogenic neurological disease: a systematic review and meta-analysis of 831 cases","volume":"77","author":"Bai","year":"2015","journal-title":"Neurosurgery"},{"issue":"3","key":"10.1016\/j.bas.2022.100863_bib4","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.clineuro.2008.10.003","article-title":"Evaluation of brain biopsy in the diagnosis of severe neurologic disease of unknown etiology","volume":"111","author":"Burns","year":"2009","journal-title":"Clin. Neurol. Neurosurg."},{"issue":"5","key":"10.1016\/j.bas.2022.100863_bib5","first-page":"995","article-title":"Brain biopsy in benign neurological disease","volume":"259","author":"Gilkes","year":"2012","journal-title":"J.\u00a0Neurol."},{"issue":"1","key":"10.1016\/j.bas.2022.100863_bib6","doi-asserted-by":"crossref","first-page":"72","DOI":"10.3171\/jns.2007.106.1.72","article-title":"The diagnostic utility of brain biopsy procedures in patients with rapidly deteriorating neurological conditions or dementia","volume":"106","author":"Josephson","year":"2007","journal-title":"J.\u00a0Neurosurg."},{"issue":"7","key":"10.1016\/j.bas.2022.100863_bib7","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1136\/jnnp-2015-312037","article-title":"Safety and diagnostic value of brain biopsy in HIV patients: a case series and meta-analysis of 1209 patients","volume":"87","author":"Lee","year":"2016","journal-title":"J.\u00a0Neurol. Neurosurg. Psychiatry"},{"issue":"5","key":"10.1016\/j.bas.2022.100863_bib8","doi-asserted-by":"crossref","first-page":"637","DOI":"10.3109\/02688697.2014.887657","article-title":"Yield and complications of frame-based and frameless stereotactic brain biopsy\u2013the value of intra-operative histological analysis","volume":"28","author":"Livermore","year":"2014","journal-title":"Br. J. Neurosurg."},{"issue":"6","key":"10.1016\/j.bas.2022.100863_bib9","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1007\/s00701-019-03910-8","article-title":"Brain biopsy in suspected non-neoplastic neurological disease","volume":"161","author":"Noronha","year":"2019","journal-title":"Acta Neurochir."},{"issue":"23","key":"10.1016\/j.bas.2022.100863_bib10","doi-asserted-by":"crossref","first-page":"1643","DOI":"10.1056\/NEJM199212033272306","article-title":"Toxoplasmosis of the central nervous system in the acquired immunodeficiency syndrome","volume":"327","author":"Porter","year":"1992","journal-title":"N.\u00a0Engl. J. Med."},{"issue":"4","key":"10.1016\/j.bas.2022.100863_bib11","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1227\/01.neu.0000318168.97966.17","article-title":"Impact of brain biopsy on the management of patients with nonneoplastic undiagnosed neurological disorders","volume":"62","author":"Pulhorn","year":"2008","journal-title":"Neurosurgery"},{"issue":"5","key":"10.1016\/j.bas.2022.100863_bib12","doi-asserted-by":"crossref","first-page":"614","DOI":"10.3109\/02688697.2010.551677","article-title":"Brain biopsy in cryptogenic neurological disease","volume":"25","author":"Rice","year":"2011","journal-title":"Br. J. Neurosurg."},{"issue":"5","key":"10.1016\/j.bas.2022.100863_bib13","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1212\/WNL.0b013e3181eb5889","article-title":"Open biopsy in patients with acute progressive neurologic decline and absence of mass lesion","volume":"75","author":"Schuette","year":"2010","journal-title":"Neurology"},{"issue":"1","key":"10.1016\/j.bas.2022.100863_bib14","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1159\/000315032","article-title":"Brain biopsy in the management of neurology patients","volume":"64","author":"Wong","year":"2010","journal-title":"Eur. Neurol."}],"container-title":["Brain and Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772529422000042?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772529422000042?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T11:16:49Z","timestamp":1757416609000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772529422000042"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":14,"alternative-id":["S2772529422000042"],"URL":"https:\/\/doi.org\/10.1016\/j.bas.2022.100863","relation":{},"ISSN":["2772-5294"],"issn-type":[{"value":"2772-5294","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impact of brain biopsy on management of nonneoplastic brain disease","name":"articletitle","label":"Article Title"},{"value":"Brain and Spine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bas.2022.100863","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V. on behalf of EUROSPINE, the Spine Society of Europe, EANS, the European Association of Neurosurgical Societies.","name":"copyright","label":"Copyright"}],"article-number":"100863"}}