{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:55:35Z","timestamp":1791453335975,"version":"4.3.3"},"reference-count":36,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"vor","delay-in-days":239,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Brain and Spine"],"published-print":{"date-parts":[[2026]]},"DOI":"10.1016\/j.bas.2026.106668","type":"journal-article","created":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T15:02:33Z","timestamp":1788620553000},"page":"106668","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Beyond the MRI-positive\/MRI-negative dichotomy: A stepwise surgical strategy for Cushing's disease"],"prefix":"10.1016","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9287-5239","authenticated-orcid":false,"given":"Luca","family":"Ferlendis","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3698-5855","authenticated-orcid":false,"given":"Hung Thanh","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thibault","family":"Passeri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Villa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Leclercq","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0360-0875","authenticated-orcid":false,"given":"Maxime","family":"Barat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2117-163X","authenticated-orcid":false,"given":"Arianna","family":"Fava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Beccaria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Assi\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9bastien","family":"Froelich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0735-8278","authenticated-orcid":false,"given":"Bertrand","family":"Baussart","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib1","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1007\/s10143-023-02077-2","article-title":"The utility of PET for detecting corticotropinomas in Cushing disease: a scoping review","volume":"46","author":"Bauman","year":"2023","journal-title":"Neurosurg. Rev."},{"issue":"3","key":"10.1016\/j.bas.2026.106668_bib3","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1007\/s00701-020-04542-z","article-title":"Mononostril endoscopic endonasal approach for pituitary surgery","volume":"163","author":"Baussart","year":"2021","journal-title":"Acta Neurochir."},{"issue":"11","key":"10.1016\/j.bas.2026.106668_bib2","doi-asserted-by":"crossref","first-page":"3155","DOI":"10.1007\/s00701-021-04995-w","article-title":"Pituitary surgery for Cushing's disease","volume":"163","author":"Baussart","year":"2021","journal-title":"Acta Neurochir."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib5","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1007\/s00701-024-06152-5","article-title":"Diaphragm reconstruction using a TachoSil patch as alternative to intrasellar packing for small focal diaphragm defects in pituitary surgery: a cohort study","volume":"166","author":"Baussart","year":"2024","journal-title":"Acta Neurochir."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib6","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1007\/s10143-025-03656-1","article-title":"Specific focus on the basal dura for improving Cushing's disease surgery: a cohort study","volume":"48","author":"Baussart","year":"2025","journal-title":"Neurosurg. Rev."},{"key":"10.1016\/j.bas.2026.106668_bib4","article-title":"Closure strategy for endoscopic pituitary surgery: experience from 3015 patients","volume":"12","author":"Baussart","year":"2022","journal-title":"Front. Oncol."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib7","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1007\/s10143-025-03797-3","article-title":"Outcome of acromegalic patients undergoing endoscopic endonasal surgery: collaborative French and Italian cohort, a 25-year experience","volume":"48","author":"Baussart","year":"2025","journal-title":"Neurosurg. Rev."},{"issue":"6","key":"10.1016\/j.bas.2026.106668_bib9","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1007\/s11102-021-01160-5","article-title":"Selective resection of cushing microadenoma guided by preoperative hybrid 18-fluoroethyl-L-tyrosine and 11-C-methionine PET\/MRI","volume":"24","author":"Berkmann","year":"2021","journal-title":"Pituitary"},{"issue":"4","key":"10.1016\/j.bas.2026.106668_bib10","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1227\/01.NEU.0000137330.02549.0D","article-title":"Endoscopic endonasal transsphenoidal surgery","volume":"55","author":"Cappabianca","year":"2004","journal-title":"Neurosurgery"},{"issue":"7","key":"10.1016\/j.bas.2026.106668_bib12","doi-asserted-by":"crossref","first-page":"1227","DOI":"10.1007\/s00701-017-3140-1","article-title":"Efficacy of endoscopic endonasal transsphenoidal surgery for Cushing's disease in 230 patients with positive and negative MRI","volume":"159","author":"Cebula","year":"2017","journal-title":"Acta Neurochir."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib13","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3171\/2018.5.JNS18595","article-title":"The medial wall of the cavernous sinus. Part 2: selective medial wall resection in 50 pituitary adenoma patients","volume":"131","author":"Cohen-Cohen","year":"2019","journal-title":"J. Neurosurg."},{"issue":"9","key":"10.1016\/j.bas.2026.106668_bib14","doi-asserted-by":"crossref","first-page":"4101","DOI":"10.1210\/jc.2019-00333","article-title":"Why we should still treat by neurosurgery patients with cushing disease and a normal or inconclusive pituitary MRI","volume":"104","author":"Cristante","year":"2019","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"11","key":"10.1016\/j.bas.2026.106668_bib15","first-page":"1320","article-title":"Outcomes of transsphenoidal surgery in cushing disease patients with negative pituitary magnetic resonance imaging findings: a single-center experience","volume":"26","author":"Dai","year":"2020","journal-title":"Endocr Pract Off J Am Coll Endocrinol Am Assoc Clin Endocrinol"},{"key":"10.1016\/j.bas.2026.106668_bib16","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/01616412.2025.2606225","article-title":"The surgical management of Cushing disease: a case series from a Canadian tertiary center","author":"Estephan","year":"2025","journal-title":"Neurol. Res."},{"issue":"12","key":"10.1016\/j.bas.2026.106668_bib17","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S2213-8587(21)00235-7","article-title":"Consensus on diagnosis and management of Cushing's disease: a guideline update","volume":"9","author":"Fleseriu","year":"2021","journal-title":"Lancet Diabetes Endocrinol."},{"issue":"7","key":"10.1016\/j.bas.2026.106668_bib18","doi-asserted-by":"crossref","first-page":"e2882","DOI":"10.1210\/clinem\/dgac178","article-title":"Randomized trial of osilodrostat for the treatment of cushing disease","volume":"107","author":"Gadelha","year":"2022","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"10418","key":"10.1016\/j.bas.2026.106668_bib19","doi-asserted-by":"crossref","first-page":"2237","DOI":"10.1016\/S0140-6736(23)01961-X","article-title":"Cushing's syndrome","volume":"402","author":"Gadelha","year":"2023","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.bas.2026.106668_bib20","doi-asserted-by":"crossref","first-page":"3409","DOI":"10.1007\/s00701-023-05809-x","article-title":"Pituitary surgery outcome in patients 75 years and older: a retrospective study","volume":"165","author":"Garvayo","year":"2023","journal-title":"Acta Neurochir."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib21","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1007\/s10143-026-04168-2","article-title":"Cushing's disease and negative MRI: a single-center series, systematic literature review, and meta-analysis","volume":"49","author":"Ghidoni","year":"2026","journal-title":"Neurosurg. Rev."},{"issue":"5","key":"10.1016\/j.bas.2026.106668_bib22","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1227\/neu.0000000000002109","article-title":"Resection of the cavernous sinus medial Wall improves remission rate in functioning pituitary tumors: retrospective analysis of 248 consecutive cases","volume":"91","author":"Ishida","year":"2022","journal-title":"Neurosurgery"},{"issue":"4","key":"10.1016\/j.bas.2026.106668_bib23","doi-asserted-by":"crossref","first-page":"907","DOI":"10.3171\/2025.1.JNS241286","article-title":"Outcome metrics for primary endoscopic endonasal surgery for low-risk patients with Cushing's disease: an evidence-based position statement from the Registry of Adenomas of the Pituitary and Related Disorders consortium","volume":"143","author":"Karsy","year":"2025","journal-title":"J. Neurosurg."},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib24","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1210\/jc.2002-020374","article-title":"Accuracy of bilateral inferior petrosal or cavernous sinuses sampling in predicting the lateralization of Cushing's disease pituitary microadenoma: influence of catheter position and anatomy of venous drainage","volume":"88","author":"Lefournier","year":"2003","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"6","key":"10.1016\/j.bas.2026.106668_bib26","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.3171\/2019.3.JNS19367","article-title":"Challenging Knosp high-grade pituitary adenomas","volume":"132","author":"Micko","year":"2020","journal-title":"J. Neurosurg."},{"issue":"4","key":"10.1016\/j.bas.2026.106668_bib25","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3171\/2014.12.JNS141083","article-title":"Invasion of the cavernous sinus space in pituitary adenomas: endoscopic verification and its correlation with an MRI-based classification","volume":"122","author":"Micko","year":"2015","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.bas.2026.106668_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/2025.8.JNS251403","article-title":"Chopsticks mononostril approach with sphenoid sinus cranialization and septal mucosa suturing: a new minimally invasive concept and closure technique for endoscopic endonasal approaches","author":"Passeri","year":"2026","journal-title":"J. Neurosurg."},{"issue":"5","key":"10.1016\/j.bas.2026.106668_bib28","first-page":"688","article-title":"[18F]FET PET\/MRI: an accurate technique for detection of small functional pituitary tumors","volume":"65","author":"Pruis","year":"2024","journal-title":"J Nucl Med Off Publ Soc Nucl Med"},{"issue":"2","key":"10.1016\/j.bas.2026.106668_bib29","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1001\/jama.2023.11305","article-title":"Cushing syndrome: a review","volume":"330","author":"Reincke","year":"2023","journal-title":"JAMA"},{"issue":"11","key":"10.1016\/j.bas.2026.106668_bib30","doi-asserted-by":"crossref","first-page":"3431","DOI":"10.1007\/s00701-023-05736-x","article-title":"The \u201ccandy wrapper\u201d of the pituitary gland: a road map to the parasellar ligaments and the medial wall of the cavernous sinus","volume":"165","author":"Serioli","year":"2023","journal-title":"Acta Neurochir."},{"key":"10.1016\/j.bas.2026.106668_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.wneu.2025.124700","article-title":"Disease remission and surgical outcomes of Endoscopic transsphenoidal surgery for cushing disease: a single Center experience","volume":"206","author":"Shapey","year":"2026","journal-title":"World Neurosurg."},{"issue":"5","key":"10.1016\/j.bas.2026.106668_bib32","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s11102-020-01066-8","article-title":"Outcomes of pituitary surgery for Cushing's disease: a systematic review and meta-analysis","volume":"23","author":"Stroud","year":"2020","journal-title":"Pituitary"},{"issue":"1","key":"10.1016\/j.bas.2026.106668_bib33","doi-asserted-by":"crossref","first-page":"122","DOI":"10.3171\/2018.3.JNS18596","article-title":"The medial wall of the cavernous sinus. Part 1: surgical anatomy, ligaments, and surgical technique for its mobilization and\/or resection","volume":"131","author":"Truong","year":"2019","journal-title":"J. Neurosurg."},{"issue":"S3","key":"10.1016\/j.bas.2026.106668_bib34","article-title":"ICAR: endoscopic skull\u2010base surgery","volume":"9","author":"Wang","year":"2019","journal-title":"Int. Forum Allergy Rhinol."},{"issue":"7","key":"10.1016\/j.bas.2026.106668_bib35","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.1210\/jc.2006-0277","article-title":"Surgical remission of pituitary adenomas confined to the neurohypophysis in Cushing's disease","volume":"91","author":"Weil","year":"2006","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"6","key":"10.1016\/j.bas.2026.106668_bib36","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1210\/jc.2012-3943","article-title":"The lateralization accuracy of inferior petrosal sinus sampling in 501 patients with Cushing's disease","volume":"98","author":"Wind","year":"2013","journal-title":"J. Clin. Endocrinol. Metab."},{"issue":"4","key":"10.1016\/j.bas.2026.106668_bib37","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1007\/s11102-022-01239-7","article-title":"Surgical strategies in the treatment of MR-negative Cushing's disease: a systematic review and treatment algorithm","volume":"25","author":"Yang","year":"2022","journal-title":"Pituitary"},{"issue":"6","key":"10.1016\/j.bas.2026.106668_bib38","doi-asserted-by":"crossref","DOI":"10.3171\/2020.3.FOCUS2067","article-title":"Surgical outcomes and multidisciplinary management strategy of Cushing's disease: a single-center experience in China","volume":"48","author":"Zhang","year":"2020","journal-title":"Neurosurg. Focus"}],"container-title":["Brain and Spine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772529426007447?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2772529426007447?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T09:43:06Z","timestamp":1791452586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2772529426007447"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026]]},"references-count":36,"alternative-id":["S2772529426007447"],"URL":"https:\/\/doi.org\/10.1016\/j.bas.2026.106668","relation":{},"ISSN":["2772-5294"],"issn-type":[{"value":"2772-5294","type":"print"}],"subject":[],"published":{"date-parts":[[2026]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Beyond the MRI-positive\/MRI-negative dichotomy: A stepwise surgical strategy for Cushing's disease","name":"articletitle","label":"Article Title"},{"value":"Brain and Spine","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bas.2026.106668","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V. on behalf of EANS, the European Association of Neurosurgical Societies, EUROSPINE, the Spine Society of Europe.","name":"copyright","label":"Copyright"}],"article-number":"106668"}}