{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T23:21:02Z","timestamp":1778887262630,"version":"3.51.4"},"reference-count":128,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2018,5,1]],"date-time":"2018-05-01T00:00:00Z","timestamp":1525132800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,5,1]],"date-time":"2019-05-01T00:00:00Z","timestamp":1556668800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"National Basic Research Program of China","award":["2013CB531200"],"award-info":[{"award-number":["2013CB531200"]}]},{"name":"National Basic Research Program of China","award":["2012CB518000"],"award-info":[{"award-number":["2012CB518000"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81370343"],"award-info":[{"award-number":["81370343"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81370234"],"award-info":[{"award-number":["81370234"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81130073"],"award-info":[{"award-number":["81130073"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81270190"],"award-info":[{"award-number":["81270190"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81170100"],"award-info":[{"award-number":["81170100"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31671177"],"award-info":[{"award-number":["31671177"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31521062"],"award-info":[{"award-number":["31521062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Major Scientific and Technological Special Project for Significant New Drugs Development","award":["2013ZX09508104"],"award-info":[{"award-number":["2013ZX09508104"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2018,5]]},"DOI":"10.1016\/j.bbadis.2017.10.013","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T15:05:58Z","timestamp":1507820758000},"page":"1984-1990","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"PB","title":["MG53 and disordered metabolism in striated muscle"],"prefix":"10.1016","volume":"1864","author":[{"given":"Xinli","family":"Hu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui-Ping","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2017.10.013_bb0005","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.jamda.2013.02.006","article-title":"Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging","volume":"14","author":"Leenders","year":"2013","journal-title":"J. Am. Med. Dir. Assoc."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0010","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.cger.2014.08.018","article-title":"Physical function and disability in older adults with diabetes","volume":"31","author":"de Rekeneire","year":"2015","journal-title":"Clin. Geriatr. Med."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0015","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1007\/s00592-016-0880-y","article-title":"Muscle dysfunction in type 2 diabetes: a major threat to patient's mobility and independence","volume":"53","author":"Bianchi","year":"2016","journal-title":"Acta Diabetol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0020","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1016\/0002-9149(72)90595-4","article-title":"New type of cardiomyopathy associated with diabetic glomerulosclerosis","volume":"30","author":"Rubler","year":"1972","journal-title":"Am. J. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0025","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/HJH.0b013e3283331169","article-title":"Diabetes and incident heart failure in hypertensive and normotensive participants of the Strong Heart study","volume":"28","author":"de Simone","year":"2010","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0030","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.numecd.2011.06.007","article-title":"Does cardiovascular phenotype explain the association between diabetes and incident heart failure? The Strong Heart study","volume":"23","author":"de Simone","year":"2013","journal-title":"Nutr. Metab. Cardiovasc. Dis."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0035","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1007\/s00125-014-3171-6","article-title":"Molecular mechanisms of diabetic cardiomyopathy","volume":"57","author":"Bugger","year":"2014","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0040","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1172\/JCI60329","article-title":"Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice","volume":"122","author":"Battiprolu","year":"2012","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0045","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1161\/CIRCHEARTFAILURE.114.001457","article-title":"Activation of Foxo1 by insulin resistance promotes cardiac dysfunction and beta-myosin heavy chain gene expression","volume":"8","author":"Qi","year":"2015","journal-title":"Circ. Heart Fail."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0050","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3389\/fphys.2016.00125","article-title":"New molecular insights of insulin in diabetic cardiomyopathy","volume":"7","author":"Westermeier","year":"2016","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0055","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/nrendo.2015.216","article-title":"Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy","volume":"12","author":"Jia","year":"2016","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0060","doi-asserted-by":"crossref","first-page":"1784","DOI":"10.1073\/pnas.97.4.1784","article-title":"Lipotoxic heart disease in obese rats: implications for human obesity","volume":"97","author":"Zhou","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0065","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1073\/pnas.0336724100","article-title":"A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content","volume":"100","author":"Finck","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0070","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1016\/j.bbalip.2016.02.011","article-title":"Lipotoxicity in obesity and diabetes-related cardiac dysfunction","volume":"1860","author":"Zlobine","year":"2016","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0075","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.2337\/diabetes.53.5.1336","article-title":"Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes","volume":"53","author":"Ye","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0080","doi-asserted-by":"crossref","first-page":"798","DOI":"10.2337\/diabetes.55.03.06.db05-1039","article-title":"Protection of cardiac mitochondria by overexpression of MnSOD reduces diabetic cardiomyopathy","volume":"55","author":"Shen","year":"2006","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0085","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.pharmthera.2016.11.013","article-title":"Cardiac oxidative stress in diabetes: mechanisms and therapeutic potential","volume":"172","author":"Faria","year":"2017","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0090","doi-asserted-by":"crossref","first-page":"H118","DOI":"10.1152\/ajpheart.00932.2010","article-title":"Increased propensity for cell death in diabetic human heart is mediated by mitochondrial-dependent pathways","volume":"300","author":"Anderson","year":"2011","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0095","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1161\/CIRCULATIONAHA.113.008476","article-title":"Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in type 2 diabetic but not in obese patients","volume":"130","author":"Montaigne","year":"2014","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0100","doi-asserted-by":"crossref","first-page":"2457","DOI":"10.2337\/db07-0481","article-title":"Mitochondrial energetics in the heart in obesity-related diabetes: direct evidence for increased uncoupled respiration and activation of uncoupling proteins","volume":"56","author":"Boudina","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0105","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1089\/ars.2015.6294","article-title":"The mitochondria in diabetic heart failure: from pathogenesis to therapeutic promise","volume":"22","author":"Schilling","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0110","first-page":"H148","article-title":"Diabetes rapidly induces contractile dysfunctions in isolated ventricular myocytes","volume":"272","author":"Ren","year":"1997","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0115","first-page":"H2185","article-title":"Alterations in contractile properties and Ca2+ handling in streptozotocin-induced diabetic rat myocardium","volume":"277","author":"Ishikawa","year":"1999","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0120","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.ceca.2014.08.004","article-title":"Calcium signaling in diabetic cardiomyocytes","volume":"56","author":"Pereira","year":"2014","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0125","doi-asserted-by":"crossref","first-page":"641","DOI":"10.2337\/db06-1163","article-title":"Contributions of inflammation and cardiac matrix metalloproteinase activity to cardiac failure in diabetic cardiomyopathy: the role of angiotensin type 1 receptor antagonism","volume":"56","author":"Westermann","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0130","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1161\/HYPERTENSIONAHA.114.04737","article-title":"Uric acid promotes left ventricular diastolic dysfunction in mice fed a Western diet","volume":"65","author":"Jia","year":"2015","journal-title":"Hypertension"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0135","doi-asserted-by":"crossref","first-page":"8917578","DOI":"10.1155\/2016\/8917578","article-title":"Update on RAAS modulation for the treatment of diabetic cardiovascular disease","volume":"2016","author":"Bernardi","year":"2016","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0140","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1038\/ncpcardio1347","article-title":"Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy","volume":"5","author":"Lebeche","year":"2008","journal-title":"Nat. Clin. Pract. Cardiovasc. Med."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0145","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1016\/j.bbadis.2014.06.030","article-title":"Interplay of oxidative, nitrosative\/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy","volume":"1852","author":"Varga","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0150","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1038\/ncb1812","article-title":"MG53 nucleates assembly of cell membrane repair machinery","volume":"11","author":"Cai","year":"2009","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0155","doi-asserted-by":"crossref","first-page":"15894","DOI":"10.1074\/jbc.M109.009589","article-title":"Membrane repair defects in muscular dystrophy are linked to altered interaction between MG53, caveolin-3, and dysferlin","volume":"284","author":"Cai","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0160","doi-asserted-by":"crossref","first-page":"2565","DOI":"10.1161\/CIRCULATIONAHA.110.954628","article-title":"MG53 constitutes a primary determinant of cardiac ischemic preconditioning","volume":"121","author":"Cao","year":"2010","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0165","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1093\/cvr\/cvr029","article-title":"MG53 participates in ischaemic postconditioning through the RISK signalling pathway","volume":"91","author":"Zhang","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0170","first-page":"505","article-title":"MG53 is a double-edged sword for human diseases","volume":"68","author":"Zhang","year":"2016","journal-title":"Sheng Li Xue Bao"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0175","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nature11834","article-title":"Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders","volume":"494","author":"Song","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0180","doi-asserted-by":"crossref","first-page":"2354","DOI":"10.1038\/ncomms3354","article-title":"MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling","volume":"4","author":"Yi","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0185","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1161\/CIRCULATIONAHA.114.012285","article-title":"Upregulation of MG53 induces diabetic cardiomyopathy through transcriptional activation of peroxisome proliferation-activated receptor alpha","volume":"131","author":"Liu","year":"2015","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0190","doi-asserted-by":"crossref","DOI":"10.3390\/ijms17122136","article-title":"Diabetic cardiomyopathy: does the type of diabetes matter?","volume":"17","author":"Holscher","year":"2016","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0195","doi-asserted-by":"crossref","first-page":"E1049","DOI":"10.1152\/ajpendo.00560.2009","article-title":"Abnormal in vivo myocardial energy substrate uptake in diet-induced type 2 diabetic cardiomyopathy in rats","volume":"298","author":"Menard","year":"2010","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0200","doi-asserted-by":"crossref","first-page":"5341","DOI":"10.1210\/en.2005-0938","article-title":"Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity","volume":"146","author":"Buchanan","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0205","doi-asserted-by":"crossref","first-page":"1355","DOI":"10.1007\/s001250051076","article-title":"Oxidative stress measurement by in vivo electron spin resonance spectroscopy in rats with streptozotocin-induced diabetes","volume":"41","author":"Sano","year":"1998","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0210","doi-asserted-by":"crossref","first-page":"25234","DOI":"10.3390\/ijms161025234","article-title":"Diabetic cardiovascular disease induced by oxidative stress","volume":"16","author":"Kayama","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0215","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1089\/ars.2015.6311","article-title":"Metabolic alterations induce oxidative stress in diabetic and failing hearts: different pathways, same outcome","volume":"22","author":"Roul","year":"2015","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0220","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1056\/NEJMoa031314","article-title":"Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes","volume":"350","author":"Petersen","year":"2004","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0225","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.2337\/db06-0783","article-title":"Impaired mitochondrial substrate oxidation in muscle of insulin-resistant offspring of type 2 diabetic patients","volume":"56","author":"Befroy","year":"2007","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0230","doi-asserted-by":"crossref","first-page":"H54","DOI":"10.1152\/ajpheart.00845.2013","article-title":"Functional deficiencies of subsarcolemmal mitochondria in the type 2 diabetic human heart","volume":"307","author":"Croston","year":"2014","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0235","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.yjmcc.2015.12.011","article-title":"Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities","volume":"90","author":"Russo","year":"2016","journal-title":"J. Mol. Cell Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0240","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1016\/j.yjmcc.2010.02.012","article-title":"Insulin signaling regulates cardiac titin properties in heart development and diabetic cardiomyopathy","volume":"48","author":"Kruger","year":"2010","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0245","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.ijcard.2016.04.178","article-title":"Worse cardiac remodeling in response to pressure overload in type 2 diabetes mellitus","volume":"217","author":"Goncalves","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0250","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/s10741-016-9536-9","article-title":"The fibrosis-cell death axis in heart failure","volume":"21","author":"Piek","year":"2016","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0255","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1038\/nature12537","article-title":"Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation","volume":"502","author":"Erickson","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0260","doi-asserted-by":"crossref","first-page":"3160","DOI":"10.1016\/j.ijcard.2013.07.150","article-title":"An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy","volume":"168","author":"Palomer","year":"2013","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0265","doi-asserted-by":"crossref","first-page":"H153","DOI":"10.1152\/ajpheart.01142.2008","article-title":"Superoxide production by NAD(P)H oxidase and mitochondria is increased in genetically obese and hyperglycemic rat heart and aorta before the development of cardiac dysfunction. The role of glucose-6-phosphate dehydrogenase-derived NADPH","volume":"297","author":"Serpillon","year":"2009","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0270","doi-asserted-by":"crossref","first-page":"2318","DOI":"10.2337\/db12-1391","article-title":"Hyperglycemia-induced protein kinase C beta2 activation induces diastolic cardiac dysfunction in diabetic rats by impairing caveolin-3 expression and Akt\/eNOS signaling","volume":"62","author":"Lei","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0275","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.lfs.2013.06.002","article-title":"Inhibition of protein kinase C betaII isoform rescues glucose toxicity-induced cardiomyocyte contractile dysfunction: role of mitochondria","volume":"93","author":"Wang","year":"2013","journal-title":"Life Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0280","doi-asserted-by":"crossref","first-page":"1103","DOI":"10.1016\/j.yjmcc.2012.02.006","article-title":"Activation of CaMKII as a key regulator of reactive oxygen species production in diabetic rat heart","volume":"52","author":"Nishio","year":"2012","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0285","doi-asserted-by":"crossref","first-page":"224","DOI":"10.1161\/01.CIR.99.2.224","article-title":"In vivo formation of 8-iso-prostaglandin f2alpha and platelet activation in diabetes mellitus: effects of improved metabolic control and vitamin E supplementation","volume":"99","author":"Davi","year":"1999","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0290","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/S0140-6736(96)90013-6","article-title":"Oxidative damage to DNA in diabetes mellitus","volume":"347","author":"Dandona","year":"1996","journal-title":"Lancet"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0295","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.2337\/diacare.26.5.1507","article-title":"Evaluation of urinary 8-hydroxydeoxy-guanosine as a novel biomarker of macrovascular complications in type 2 diabetes","volume":"26","author":"Nishikawa","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0300","doi-asserted-by":"crossref","first-page":"510619","DOI":"10.1155\/2014\/510619","article-title":"Study of the correlations among some parameters of the oxidative status, gelatinases, and their inhibitors in a group of subjects with metabolic syndrome","volume":"2014","author":"Hopps","year":"2014","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0305","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1007\/s40618-014-0111-8","article-title":"Oxidatively modified forms of albumin in patients with risk factors of metabolic syndrome","volume":"37","author":"Zurawska-Plaksej","year":"2014","journal-title":"J. Endocrinol. Investig."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0310","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bbalip.2003.07.002","article-title":"Increased accumulation of the glycoxidation product N\u03b5-(carboxymethyl)lysine in hearts of diabetic patients: generation and characterisation of a monoclonal anti-CML antibody","volume":"1636","author":"Schalkwijk","year":"2004","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0315","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s10741-013-9374-y","article-title":"Advanced glycation end products: role in pathology of diabetic cardiomyopathy","volume":"19","author":"Bodiga","year":"2014","journal-title":"Heart Fail. Rev."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0320","doi-asserted-by":"crossref","first-page":"1825","DOI":"10.2337\/diabetes.52.7.1825","article-title":"Chronic diabetes increases advanced glycation end products on cardiac ryanodine receptors\/calcium-release channels","volume":"52","author":"Bidasee","year":"2003","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0325","doi-asserted-by":"crossref","first-page":"463","DOI":"10.2337\/diabetes.53.2.463","article-title":"Diabetes increases formation of advanced glycation end products on Sarco(endo)plasmic reticulum Ca2+-ATPase","volume":"53","author":"Bidasee","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0330","first-page":"H2126","article-title":"Habitual exercise attenuates myocardial stiffness in diabetes mellitus in rats","volume":"271","author":"Woodiwiss","year":"1996","journal-title":"Am. J. Phys."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0335","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1097\/00004872-200301000-00002","article-title":"Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes","volume":"21","author":"Aronson","year":"2003","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0340","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.lfs.2012.08.006","article-title":"Post-translational protein modification by O-linked N-acetyl-glucosamine: its role in mediating the adverse effects of diabetes on the heart","volume":"92","author":"McLarty","year":"2013","journal-title":"Life Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0345","doi-asserted-by":"crossref","first-page":"E241","DOI":"10.1152\/ajpendo.00060.2002","article-title":"Enhanced O-GlcNAc protein modification is associated with insulin resistance in GLUT1-overexpressing muscles","volume":"283","author":"Buse","year":"2002","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0350","doi-asserted-by":"crossref","first-page":"5313","DOI":"10.1073\/pnas.072072399","article-title":"Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes","volume":"99","author":"Vosseller","year":"2002","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0355","doi-asserted-by":"crossref","first-page":"863","DOI":"10.2337\/diab.44.8.863","article-title":"Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications","volume":"44","author":"Unger","year":"1995","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0360","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1111\/j.1749-6632.1965.tb34800.x","article-title":"The glucose fatty acid cycle in obesity and maturity onset diabetes mellitus","volume":"131","author":"Randle","year":"1965","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0365","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s001250051123","article-title":"Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study","volume":"42","author":"Krssak","year":"1999","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0370","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.2337\/diabetes.48.8.1600","article-title":"Intramyocellular triglyceride content is a determinant of in vivo insulin resistance in humans: a 1H-13C nuclear magnetic resonance spectroscopy assessment in offspring of type 2 diabetic parents","volume":"48","author":"Perseghin","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0375","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.2337\/diabetes.48.5.1113","article-title":"Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects","volume":"48","author":"Jacob","year":"1999","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0380","doi-asserted-by":"crossref","first-page":"2267","DOI":"10.1016\/S0140-6736(10)60408-4","article-title":"Lipid-induced insulin resistance: unravelling the mechanism","volume":"375","author":"Samuel","year":"2010","journal-title":"Lancet"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0385","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/nature13478","article-title":"The role of hepatic lipids in hepatic insulin resistance and type 2 diabetes","volume":"510","author":"Perry","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0390","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1172\/JCI77812","article-title":"The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux","volume":"126","author":"Samuel","year":"2016","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0395","doi-asserted-by":"crossref","first-page":"S10","DOI":"10.1016\/j.amjmed.2006.01.009","article-title":"Etiology of insulin resistance","volume":"119","author":"Petersen","year":"2006","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0400","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0002-9343(99)00414-3","article-title":"Lipodystrophies","volume":"108","author":"Garg","year":"2000","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0405","doi-asserted-by":"crossref","first-page":"1345","DOI":"10.1172\/JCI0215001","article-title":"Leptin reverses insulin resistance and hepatic steatosis in patients with severe lipodystrophy","volume":"109","author":"Petersen","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0410","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.bbalip.2005.03.005","article-title":"Fatty acid metabolism is enhanced in type 2 diabetic hearts","volume":"1734","author":"Carley","year":"2005","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0415","doi-asserted-by":"crossref","first-page":"1938","DOI":"10.1007\/s00125-007-0735-8","article-title":"Cardiac contractile dysfunction in insulin-resistant rats fed a high-fat diet is associated with elevated CD36-mediated fatty acid uptake and esterification","volume":"50","author":"Ouwens","year":"2007","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0420","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.cmet.2007.01.002","article-title":"Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance","volume":"5","author":"Holland","year":"2007","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0425","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.2337\/db09-1293","article-title":"Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption","volume":"59","author":"Ussher","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0430","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.tem.2015.07.006","article-title":"Ceramides \u2013 lipotoxic inducers of metabolic disorders","volume":"26","author":"Chaurasia","year":"2015","journal-title":"Trends Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0435","doi-asserted-by":"crossref","first-page":"36312","DOI":"10.1074\/jbc.M109.049817","article-title":"DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity","volume":"284","author":"Liu","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0440","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1093\/cvr\/cvq266","article-title":"Cardiac diacylglycerol accumulation in high fat-fed mice is associated with impaired insulin-stimulated glucose oxidation","volume":"89","author":"Zhang","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0445","doi-asserted-by":"crossref","first-page":"33588","DOI":"10.1074\/jbc.M507621200","article-title":"Peroxisome proliferator-activated receptor-\u03b3 co-activator 1\u03b1-mediated metabolic remodeling of skeletal myocytes mimics exercise training and reverses lipid-induced mitochondrial inefficiency","volume":"280","author":"Koves","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0450","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.cmet.2007.10.013","article-title":"Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance","volume":"7","author":"Koves","year":"2008","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0455","doi-asserted-by":"crossref","first-page":"282","DOI":"10.3389\/fphys.2014.00282","article-title":"Mitochondrial and cellular mechanisms for managing lipid excess","volume":"5","author":"Aon","year":"2014","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0460","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1172\/JCI10947","article-title":"A novel mouse model of lipotoxic cardiomyopathy","volume":"107","author":"Chiu","year":"2001","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0465","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1172\/JCI16751","article-title":"Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy","volume":"111","author":"Yagyu","year":"2003","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0470","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1172\/JCI0214080","article-title":"The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus","volume":"109","author":"Finck","year":"2002","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0475","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.2337\/db13-1763","article-title":"Insulin inhibits cardiac contractility by inducing a Gi-biased beta2-adrenergic signaling in hearts","volume":"63","author":"Fu","year":"2014","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0480","doi-asserted-by":"crossref","first-page":"5319","DOI":"10.1172\/JCI71171","article-title":"Insulin receptor substrate signaling suppresses neonatal autophagy in the heart","volume":"123","author":"Riehle","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0485","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1016\/j.bbamcr.2015.02.005","article-title":"Defective insulin signaling and mitochondrial dynamics in diabetic cardiomyopathy","volume":"1853","author":"Westermeier","year":"2015","journal-title":"Biochim. Biophys. Acta, Mol. Cell Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0490","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1016\/j.jacc.2006.06.078","article-title":"Myocardial glucose transport and utilization in patients with type 2 diabetes mellitus, left ventricular dysfunction, and coronary artery disease","volume":"48","author":"Dutka","year":"2006","journal-title":"J. Am. Coll. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0495","doi-asserted-by":"crossref","first-page":"3020","DOI":"10.2337\/diabetes.51.10.3020","article-title":"Independent association of type 2 diabetes and coronary artery disease with myocardial insulin resistance","volume":"51","author":"Iozzo","year":"2002","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0500","doi-asserted-by":"crossref","first-page":"2366","DOI":"10.2337\/diabetes.53.9.2366","article-title":"Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob\/ob mouse hearts","volume":"53","author":"Mazumder","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0505","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1007\/s00018-011-0690-x","article-title":"Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes","volume":"68","author":"Steinbusch","year":"2011","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0510","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.2337\/diabetes.53.7.1655","article-title":"Enhanced sarcolemmal FAT\/CD36 content and triacylglycerol storage in cardiac myocytes from obese zucker rats","volume":"53","author":"Coort","year":"2004","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0515","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/13813450701422617","article-title":"Mechanisms responsible for enhanced fatty acid utilization by perfused hearts from type 2 diabetic db\/db mice","volume":"113","author":"Carley","year":"2007","journal-title":"Arch. Physiol. Biochem."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0520","doi-asserted-by":"crossref","first-page":"E452","DOI":"10.1152\/ajpendo.00437.2015","article-title":"Assessment of myocardial metabolic flexibility and work efficiency in human type 2 diabetes using 16-[18F]fluoro-4-thiapalmitate, a novel PET fatty acid tracer","volume":"310","author":"Mather","year":"2016","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0525","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1113\/JP271242","article-title":"Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation","volume":"594","author":"Mansor","year":"2016","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0530","doi-asserted-by":"crossref","first-page":"2407","DOI":"10.2337\/db10-0771","article-title":"G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity","volume":"59","author":"Garcia-Guerra","year":"2010","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0535","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1161\/CIRCULATIONAHA.110.988642","article-title":"G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia","volume":"123","author":"Ciccarelli","year":"2011","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0540","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1016\/j.cellsig.2014.11.018","article-title":"Insulin induces IRS2-dependent and GRK2-mediated \u03b22AR internalization to attenuate \u03b2AR signaling in cardiomyocytes","volume":"27","author":"Fu","year":"2015","journal-title":"Cell. Signal."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0545","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1161\/CIRCULATIONAHA.116.022281","article-title":"Inhibiting insulin-mediated \u03b2 2-adrenergic receptor activation prevents diabetes-associated cardiac dysfunction","volume":"135","author":"Wang","year":"2017","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0550","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.yjmcc.2015.12.025","article-title":"Mitochondrial quality control in the diabetic heart","volume":"95","author":"Liang","year":"2016","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0555","doi-asserted-by":"crossref","first-page":"847827","DOI":"10.1155\/2014\/847827","article-title":"Activation of toll-like receptors and inflammasome complexes in the diabetic cardiomyopathy-associated inflammation","volume":"2014","author":"Fuentes-Antras","year":"2014","journal-title":"Int. J. Endocrinol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0560","doi-asserted-by":"crossref","first-page":"412","DOI":"10.1038\/nrcardio.2017.35","article-title":"Myocardial stress and autophagy: mechanisms and potential therapies","volume":"14","author":"Delbridge","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0565","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1016\/j.bbadis.2014.05.020","article-title":"Autophagy and mitophagy in diabetic cardiomyopathy","volume":"1852","author":"Kobayashi","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0570","doi-asserted-by":"crossref","first-page":"2070","DOI":"10.1016\/j.bbadis.2017.03.013","article-title":"Role of microRNA in diabetic cardiomyopathy: from mechanism to intervention","volume":"1863","author":"Guo","year":"2017","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0575","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1161\/CIRCRESAHA.109.215822","article-title":"Cardioprotection of ischemia\/reperfusion injury by cholesterol-dependent MG53-mediated membrane repair","volume":"107","author":"Wang","year":"2010","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0580","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1038\/mt.2012.5","article-title":"Enhancing muscle membrane repair by gene delivery of MG53 ameliorates muscular dystrophy and heart failure in delta-sarcoglycan-deficient hamsters","volume":"20","author":"He","year":"2012","journal-title":"Mol. Ther."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0585","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.yjmcc.2014.12.010","article-title":"Cardioprotection of recombinant human MG53 protein in a porcine model of ischemia and reperfusion injury","volume":"80","author":"Liu","year":"2015","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0590","doi-asserted-by":"crossref","DOI":"10.1016\/j.tibs.2017.01.002","article-title":"TRIM family proteins: roles in autophagy, immunity, and carcinogenesis","author":"Hatakeyama","year":"2017","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0595","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1038\/cdd.2010.1","article-title":"TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1","volume":"17","author":"Lee","year":"2010","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0600","doi-asserted-by":"crossref","first-page":"3209","DOI":"10.1074\/jbc.M113.525154","article-title":"Mitsugumin 53 (MG53) ligase ubiquitinates focal adhesion kinase during skeletal myogenesis","volume":"289","author":"Nguyen","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0605","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s10974-015-9415-3","article-title":"Focal adhesion kinase and its role in skeletal muscle","volume":"36","author":"Graham","year":"2015","journal-title":"J. Muscle Res. Cell Motil."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0610","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1172\/JCI0213946","article-title":"Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression","volume":"109","author":"Belke","year":"2002","journal-title":"J. Clin. Investig."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0615","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.2337\/diab.30.12.1000","article-title":"The effect of insulin on the disposal of intravenous glucose: results from indirect calorimetry and hepatic and femoral venous catheterization","volume":"30","author":"DeFronzo","year":"1981","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0620","doi-asserted-by":"crossref","first-page":"1564386","DOI":"10.1155\/2016\/1564386","article-title":"Swimming exercise alleviated insulin resistance by regulating tripartite motif family protein 72 expression and AKT signal pathway in Sprague-Dawley rats fed with high-fat diet","volume":"2016","author":"Qi","year":"2016","journal-title":"J. Diabetes Res."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0625","article-title":"Proteomic analysis of skeletal muscle in insulin-resistant mice: response to 6-week aerobic exercise","volume":"8","author":"Yuan","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0630","doi-asserted-by":"crossref","first-page":"1450","DOI":"10.1016\/j.bbalip.2016.03.018","article-title":"The role of CD36 in the regulation of myocardial lipid metabolism","volume":"1861","author":"Kim","year":"2016","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbadis.2017.10.013_bb0635","doi-asserted-by":"crossref","first-page":"414","DOI":"10.5483\/BMBRep.2016.49.8.079","article-title":"Dual function of MG53 in membrane repair and insulin signaling","volume":"49","author":"Tan","year":"2016","journal-title":"BMB Rep."},{"key":"10.1016\/j.bbadis.2017.10.013_bb0640","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1093\/cvr\/cvw017","article-title":"Lack of MG53 in human heart precludes utility as a biomarker of myocardial injury or endogenous cardioprotective factor","volume":"110","author":"Lemckert","year":"2016","journal-title":"Cardiovasc. Res."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544391730368X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544391730368X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,8,9]],"date-time":"2019-08-09T09:44:07Z","timestamp":1565343847000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092544391730368X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,5]]},"references-count":128,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2018,5]]}},"alternative-id":["S092544391730368X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2017.10.013","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2018,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MG53 and disordered metabolism in striated muscle","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2017.10.013","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}