{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:38:42Z","timestamp":1790912322228,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2018,11,1]],"date-time":"2018-11-01T00:00:00Z","timestamp":1541030400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31671185"],"award-info":[{"award-number":["31671185"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31171098"],"award-info":[{"award-number":["31171098"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013286","name":"Specialized Research Fund for the Doctoral Program of Higher Education of China","doi-asserted-by":"crossref","award":["20121323110008"],"award-info":[{"award-number":["20121323110008"]}],"id":[{"id":"10.13039\/501100013286","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Higher Innovation Team Leading Talent Cultivation Plan of Hebei","award":["LJRC017"],"award-info":[{"award-number":["LJRC017"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2018,11]]},"DOI":"10.1016\/j.bbadis.2018.09.005","type":"journal-article","created":{"date-parts":[[2018,9,7]],"date-time":"2018-09-07T06:08:03Z","timestamp":1536300483000},"page":"3723-3738","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":44,"title":["Alpha-lipoic acid regulates the autophagy of vascular smooth muscle cells in diabetes by elevating hydrogen sulfide level"],"prefix":"10.1016","volume":"1864","author":[{"given":"Xuan","family":"Qiu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuanzhi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Jin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinghui","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Teng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qi","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhong","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuming","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2018.09.005_bb0005","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1007\/s12013-015-0598-4","article-title":"Epidemiological perspectives of diabetes","volume":"73","author":"Tao","year":"2015","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0010","doi-asserted-by":"crossref","first-page":"27","DOI":"10.5551\/jat.RV17014","article-title":"Mechanism of development of atherosclerosis and cardiovascular disease in diabetes mellitus","volume":"25","author":"Katakami","year":"2018","journal-title":"J. Atheroscler. Thromb."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0015","doi-asserted-by":"crossref","first-page":"2122","DOI":"10.1007\/s00125-013-2974-1","article-title":"Vascular smooth muscle function in type 2 diabetes mellitus: a systematic review and meta-analysis","volume":"56","author":"Montero","year":"2013","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0020","first-page":"86","article-title":"The role of vascular smooth muscle cells on the pathogenesis of atherosclerosis","volume":"39","author":"Rudijanto","year":"2007","journal-title":"Acta Med. Indones."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0025","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijcard.2016.02.128","article-title":"The roles of autophagy in vascular smooth muscle cells","volume":"211","author":"Tai","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0030","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1042\/BJ20121344","article-title":"PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress","volume":"451","author":"Salabei","year":"2013","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0035","doi-asserted-by":"crossref","first-page":"613","DOI":"10.3892\/ijmm.2012.891","article-title":"ERK and Akt signaling pathways are involved in advanced glycation end product-induced autophagy in rat vascular smooth muscle cells","volume":"29","author":"Hu","year":"2012","journal-title":"Int. J. Mol. Med."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0040","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1016\/j.bbagen.2009.07.026","article-title":"Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential","volume":"1790","author":"Shay","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0045","doi-asserted-by":"crossref","first-page":"2721","DOI":"10.1517\/14656566.2014.972935","article-title":"Efficacy of \u03b1-lipoic acid in diabetic neuropathy","volume":"15","author":"Papanas","year":"2014","journal-title":"Expert. Opin. Pharmacother."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0050","doi-asserted-by":"crossref","first-page":"6746","DOI":"10.3390\/ijms14046746","article-title":"The protective effects of \u03b1-lipoic acid on kidneys in type 2 diabetic Goto-Kakisaki rats via reducing oxidative stress","volume":"14","author":"Feng","year":"2013","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0055","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1007\/s10792-016-0396-z","article-title":"Effects of alpha-lipoic acid on retinal ganglion cells, retinal thicknesses, and VEGF production in an experimental model of diabetes","volume":"37","author":"Kan","year":"2017","journal-title":"Int. Ophthalmol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0060","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1007\/s00125-006-0174-y","article-title":"Effect of R-(+)-alpha-lipoic acid on experimental diabetic retinopathy","volume":"49","author":"Lin","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0065","first-page":"23","article-title":"Effect of alpha lipoic acid on oxidative stress and vascular wall of diabetic rats","volume":"50","author":"Balkis","year":"2009","journal-title":"Romanian J. Morphol. Embryol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0070","doi-asserted-by":"crossref","first-page":"6857","DOI":"10.1007\/s11033-012-1511-5","article-title":"Alpha-lipoic acid attenuates atherosclerotic lesions and inhibits proliferation of vascular smooth muscle cells through targeting of the Ras\/MEK\/ERK signaling pathway","volume":"39","author":"Lee","year":"2012","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0075","doi-asserted-by":"crossref","first-page":"2164","DOI":"10.1161\/ATVBAHA.110.212308","article-title":"\u03b1-Lipoic acid prevents neointimal hyperplasia via induction of p38 mitogen-activated protein kinase\/Nur77-mediated apoptosis of vascular smooth muscle cells and accelerates postinjury reendothelialization","volume":"30","author":"Kim","year":"2010","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0080","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1016\/j.bbrc.2013.10.166","article-title":"Alpha-lipoic acid protects cardiomyocytes against hypoxia\/reoxygenation injury by inhibiting autophagy","volume":"441","author":"Cao","year":"2013","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0085","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1139\/cjpp-2014-0018","article-title":"The effects of alpha lipoic acid in preventing oxidative stress-induced retinal pigment epithelial cell injury","volume":"92","author":"Li","year":"2014","journal-title":"Can. J. Physiol. Pharmacol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0090","doi-asserted-by":"crossref","first-page":"180","DOI":"10.3892\/mmr.2015.3351","article-title":"\u03b1-Lipoic acid protects against hypoxia\/reoxygenation-induced injury in human umbilical vein endothelial cells through suppression of apoptosis and autophagy","volume":"12","author":"Zhang","year":"2015","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0095","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1089\/ars.2013.5309","article-title":"Production and physiological effects of hydrogen sulfide","volume":"20","author":"Kimura","year":"2014","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0100","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1089\/ars.2012.4843","article-title":"In African American type 2 diabetic patients, is vitamin D deficiency associated with lower blood levels of hydrogen sulfide and cyclic adenosine monophosphate, and elevated oxidative stress","volume":"18","author":"Jain","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0105","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1080\/0886022X.2016.1257433","article-title":"H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-\u03b21 expression","volume":"39","author":"Li","year":"2017","journal-title":"Ren. Fail."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0110","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.mad.2016.11.005","article-title":"New mechanism of lipotoxicity in diabetic cardiomyopathy: deficiency of endogenous H2S production and ER stress","volume":"162","author":"Guo","year":"2017","journal-title":"Mech. Ageing Dev."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0115","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.pharep.2014.08.001","article-title":"H2S donors attenuate diabetic nephropathy in rats: modulation of oxidant status and polyol pathway","volume":"67","author":"Safar","year":"2015","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0120","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s13578-016-0102-x","article-title":"Exogenous H2S modulates mitochondrial fusion-fission to inhibit vascular smooth muscle cell proliferation in a hyperglycemic state","volume":"6","author":"Sun","year":"2016","journal-title":"Cell Biosci."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0125","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1159\/000373973","article-title":"Calcium sensing receptor regulating smooth muscle cells proliferation through initiating cystathionine-gamma-lyase\/hydrogen sulfide pathway in diabetic rat","volume":"35","author":"Zhong","year":"2015","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0130","doi-asserted-by":"crossref","first-page":"E925","DOI":"10.1152\/ajpendo.00294.2015","article-title":"Hydrogen sulfide reduces serum triglyceride by activating liver autophagy via the AMPK-mTOR pathway","volume":"309","author":"Sun","year":"2015","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0135","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1007\/s11010-013-1946-6","article-title":"GYY4137, a novel hydrogen sulfide-releasing molecule, likely protects against high glucose-induced cytotoxicity by activation of the AMPK\/mTOR signal pathway in H9c2 cells","volume":"389","author":"Wei","year":"2014","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0140","article-title":"Hydrogen sulfide lowers proliferation and induces protective autophagy in colon epithelial cells","volume":"7","author":"Wu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0145","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/S0306-3623(96)00474-0","article-title":"The pharmacology of the antioxidant lipoic acid","volume":"29","author":"Biewenga","year":"1997","journal-title":"Gen. Pharmacol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0150","doi-asserted-by":"crossref","first-page":"388","DOI":"10.3390\/molecules22030388","article-title":"Lipoic acid as a possible pharmacological source of hydrogen sulfide\/sulfane sulfur","volume":"22","author":"Bilska-Wilkosz","year":"2017","journal-title":"Molecules"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0155","doi-asserted-by":"crossref","first-page":"2963","DOI":"10.2337\/db11-0549","article-title":"TRB3 gene silencing alleviates diabetic cardiomyopathy in a type 2 diabetic rat model","volume":"60","author":"Ti","year":"2011","journal-title":"Diabetes"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0160","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1093\/cvr\/cvr017","article-title":"ATRA activates and PDGF-BB represses the SM22\u03b1 promoter through KLF4 binding to, or dissociating from, its cis-DNA elements","volume":"90","author":"Yu","year":"2011","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0165","doi-asserted-by":"crossref","first-page":"46278","DOI":"10.1038\/srep46278","article-title":"New method for quantification of gasotransmitter hydrogen sulfide in biological matrices by LC-MS\/MS","volume":"7","author":"Tan","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0170","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1097\/HJH.0000000000001605","article-title":"Hydrogen sulfide improves endothelial dysfunction in hypertension by activating peroxisome proliferator-activated receptor delta\/endothelial nitric oxide synthase signaling","volume":"36","author":"Xiao","year":"2018","journal-title":"J. Hypertens."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0175","doi-asserted-by":"crossref","first-page":"17","DOI":"10.2169\/internalmedicine.56.7403","article-title":"Clinical implication of plasma hydrogen sulfide levels in Japanese patients with type 2 diabetes","volume":"56","author":"Suzuki","year":"2017","journal-title":"Intern. Med."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0180","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1089\/ars.2009.2956","article-title":"Low levels of hydrogen sulfide in the blood of diabetes patients and streptozotocin-treated rats causes vascular inflammation","volume":"12","author":"Jain","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0185","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.ijcard.2014.01.068","article-title":"Targeting hydrogen sulfide as a promising therapeutic strategy for atherosclerosis","volume":"172","author":"Xu","year":"2014","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0190","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1042\/BJ20110841","article-title":"Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide","volume":"439","author":"Mikami","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0195","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.1016\/j.tiv.2015.05.023","article-title":"Lipoic acid and N-acetylcysteine prevent ammonia-induced inflammatory response in C6 astroglial cells: the putative role of ERK and HO1 signaling pathways","volume":"29","author":"Santos","year":"2015","journal-title":"Toxicol. in Vitro"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0200","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.brainresbull.2018.05.019","article-title":"\u03b1-Lipoic acid attenuates oxidative stress and neurotoxicity via the ERK\/Akt-dependent pathway in the mutant hSOD1 related Drosophila model and the NSC34 cell line of amyotrophic lateral sclerosis","volume":"140","author":"Wang","year":"2018","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0205","doi-asserted-by":"crossref","first-page":"6857","DOI":"10.1007\/s11033-012-1511-5","article-title":"Alpha-lipoic acid attenuates atherosclerotic lesions and inhibits proliferation of vascular smooth muscle cells through targeting of the Ras\/MEK\/ERK signaling pathway","volume":"39","author":"Lee","year":"2012","journal-title":"Mol. Biol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0210","doi-asserted-by":"crossref","first-page":"12482","DOI":"10.3390\/ijms160612482","article-title":"Urotensin II protects cardiomyocytes from apoptosis induced by oxidative stress through the CSE\/H2S pathway","volume":"16","author":"Gong","year":"2015","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0215","first-page":"225","article-title":"Biological actions of lipoic acid associated with sulfane sulfur metabolism","volume":"60","author":"Bilska","year":"2008","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0220","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2119\/molmed.2015.00035","article-title":"Regulation of vascular tone, angiogenesis and cellular bioenergetics by the 3-mercaptopyruvate sulfurtransferase\/H2S pathway: functional impairment by hyperglycemia and restoration by dl-\u03b1-lipoic acid","volume":"21","author":"Coletta","year":"2015","journal-title":"Mol. Med."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0225","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.1016\/S1734-1140(13)71084-3","article-title":"Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide","volume":"65","author":"Dudek","year":"2013","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0230","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.pharep.2013.11.001","article-title":"Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts","volume":"66","author":"Dudek","year":"2014","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0235","first-page":"899","article-title":"Anti-inflammatory activity of lipoic acid in mice peritonitis model","volume":"70","author":"Zygmunt","year":"2013","journal-title":"Acta Pol. Pharm."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0240","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.freeradbiomed.2013.08.003","article-title":"Implications of autophagy for vascular smooth muscle cell function and plasticity","volume":"65","author":"Salabei","year":"2013","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0245","doi-asserted-by":"crossref","first-page":"1249","DOI":"10.1002\/jcb.25784","article-title":"Free fatty acids induce autophagy and LOX-1 upregulation in cultured aortic vascular smooth muscle cells","volume":"118","author":"Cheng","year":"2017","journal-title":"J. Cell. Biochem."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0250","doi-asserted-by":"crossref","first-page":"1901","DOI":"10.4161\/cc.24929","article-title":"Intermittent injections of osteocalcin reverse autophagic dysfunction and endoplasmic reticulum stress resulting from diet-induced obesity in the vascular tissue via the NF\u03baB-p65-dependent mechanism","volume":"12","author":"Zhou","year":"2013","journal-title":"Cell Cycle"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0255","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.1159\/000358676","article-title":"Autophagy protects against senescence and apoptosis via the RAS-mitochondria in high-glucose-induced endothelial cells","volume":"33","author":"Chen","year":"2014","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0260","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ijcard.2015.08.111","article-title":"Type-2 diabetes increases autophagy in the human heart through promotion of Beclin-1 mediated pathway","volume":"202","author":"Munasinghe","year":"2016","journal-title":"Int. J. Cardiol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0265","doi-asserted-by":"crossref","first-page":"24131","DOI":"10.1074\/jbc.M702824200","article-title":"p62\/SQSTM1 binds directly to Atg8\/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy","volume":"282","author":"Pankiv","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0270","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1083\/jcb.200507002","article-title":"p62\/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death","volume":"171","author":"Bj\u00f8rk\u00f8y","year":"2005","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0275","article-title":"Hydrogen sulfide releasing aspirin, ACS14, attenuates high glucose-induced increased methylglyoxal and oxidative stress in cultured vascular smooth muscle cells","volume":"9","author":"Huang","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0280","first-page":"1277","article-title":"Hydrogen sulfide, a potential novel drug, attenuates concanavalin A-induced hepatitis","volume":"8","author":"Cheng","year":"2014","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0285","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1007\/s10495-014-0978-z","article-title":"Hydrogen sulfide improves left ventricular function in smoking rats via regulation of apoptosis and autophagy","volume":"19","author":"Zhou","year":"2014","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0290","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1002\/jcp.22709","article-title":"Osteopontin stimulates autophagy via integrin\/CD44 and p38 MAPK signaling pathways in vascular smooth muscle cells","volume":"227","author":"Zheng","year":"2012","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bbadis.2018.09.005_bb0295","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.apsb.2015.07.009","article-title":"5'-monophosphate-activated protein kinase (AMPK) improves autophagic activity in diabetes and diabetic complications","volume":"6","author":"Yao","year":"2016","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bbadis.2018.09.005_bb0300","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.3892\/mmr.2017.6764","article-title":"Significance of dynamic changes in gastric smooth muscle cell apoptosis, PI3K-AKT-mTOR and AMPK-mTOR signaling in a rat model of diabetic gastroparesis","volume":"16","author":"Zhang","year":"2017","journal-title":"Mol. Med. Rep."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443918303405?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443918303405?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T17:31:07Z","timestamp":1572715867000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443918303405"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,11]]},"references-count":60,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2018,11]]}},"alternative-id":["S0925443918303405"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2018.09.005","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2018,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Alpha-lipoic acid regulates the autophagy of vascular smooth muscle cells in diabetes by elevating hydrogen sulfide level","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2018.09.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier B.V.","name":"copyright","label":"Copyright"}]}}