{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:32:05Z","timestamp":1791415925757,"version":"4.3.3"},"reference-count":199,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,3,1]],"date-time":"2021-03-01T00:00:00Z","timestamp":1614556800000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI054578"],"award-info":[{"award-number":["R01AI054578"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI136031"],"award-info":[{"award-number":["R01AI136031"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002923","name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","doi-asserted-by":"publisher","award":["PUE 22920170100106CO"],"award-info":[{"award-number":["PUE 22920170100106CO"]}],"id":[{"id":"10.13039\/501100002923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007624","name":"Emory Eye Center","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007624","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006258","name":"Comisi\u00f3n de Investigaciones Cient\u00edficas","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006258","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2020,3]]},"DOI":"10.1016\/j.bbadis.2019.165591","type":"journal-article","created":{"date-parts":[[2019,11,2]],"date-time":"2019-11-02T12:43:05Z","timestamp":1572698585000},"page":"165591","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":37,"title":["Epidemiology and pathogenesis of maternal-fetal transmission of Trypanosoma cruzi and a case for vaccine development against congenital Chagas disease"],"prefix":"10.1016","volume":"1866","author":[{"given":"Lizette","family":"Rios","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Emanuel","family":"Campos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramkumar","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Paola","family":"Zago","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nisha J.","family":"Garg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2019.165591_bb0005","unstructured":"World Health Organization, Chagas disease in Latin America: an epidemiological update based on 2010 estimates, 2015. https:\/\/www.who.int\/wer\/2015\/wer9006.pdf?ua=1. (Accessed 9\/1\/2019)."},{"issue":"10115","key":"10.1016\/j.bbadis.2019.165591_bb0010","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/S0140-6736(17)31612-4","article-title":"Chagas disease","volume":"391","author":"Perez-Molina","year":"2018","journal-title":"Lancet"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0015","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.gheart.2015.06.001","article-title":"The burden of Chagas disease: estimates and challenges","volume":"10","author":"Stanaway","year":"2015","journal-title":"Glob. Heart"},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0020","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001136","article-title":"Chagas disease has now gone global","volume":"5","author":"Tanowitz","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0025","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1128\/CMR.00005-11","article-title":"Trypanosoma cruzi and Chagas\u2019 disease in the United States","volume":"24","author":"Bern","year":"2011","journal-title":"Clin. Microbiol. Rev."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0030","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1111\/j.1537-2995.2012.03581.x","article-title":"The United States Trypanosoma cruzi infection study: evidence for vector-borne transmission of the parasite that causes Chagas disease among United States blood donors","volume":"52","author":"Cantey","year":"2012","journal-title":"Transfusion"},{"key":"10.1016\/j.bbadis.2019.165591_bb0035","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1016\/j.ejim.2017.05.001","article-title":"Chagas disease in Europe: a review for the internist in the globalized world","volume":"43","author":"Antinori","year":"2017","journal-title":"Eur. J. Intern. Med."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0040","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1186\/s40249-015-0092-7","article-title":"Preventing the transmission of American trypanosomiasis and its spread into non-endemic countries","volume":"4","author":"Liu","year":"2015","journal-title":"Infect. Dis. Poverty"},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0045","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1586\/eri.10.74","article-title":"Congenital transmission of Chagas disease: a clinical approach","volume":"8","author":"Oliveira","year":"2010","journal-title":"Expert Rev. Anti-Infect. Ther."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0050","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1590\/0074-02760140405","article-title":"Congenital Chagas disease: an update","volume":"110","author":"Carlier","year":"2015","journal-title":"Mem. Inst. Oswaldo Cruz"},{"key":"10.1016\/j.bbadis.2019.165591_bb0055","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.actatropica.2015.07.016","article-title":"Congenital Chagas disease as an ecological model of interactions between Trypanosoma cruzi parasites, pregnant women, placenta and fetuses","volume":"151","author":"Carlier","year":"2015","journal-title":"Acta Trop."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0060","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2018-001069","article-title":"The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America","volume":"3","author":"Picado","year":"2018","journal-title":"BMJ Glob. Health"},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0065","doi-asserted-by":"crossref","first-page":"e52","DOI":"10.1086\/605091","article-title":"An estimate of the burden of Chagas disease in the United States","volume":"49","author":"Bern","year":"2009","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0070","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1093\/jpids\/piw043","article-title":"Diagnosis and treatment of congenital Chagas disease in a premature infant","volume":"5","author":"Alarcon","year":"2016","journal-title":"J. Pediatric Infect. Dis. Soc."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0075","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1001\/jama.2012.9468","article-title":"Congenital Chagas disease reported in United States","volume":"308","author":"Voelker","year":"2012","journal-title":"JAMA"},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0080","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1097\/INF.0000000000001733","article-title":"Survey of pediatric infectious diseases society members about congenital Chagas disease","volume":"37","author":"Edwards","year":"2018","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.bbadis.2019.165591_bb0085","doi-asserted-by":"crossref","first-page":"e28","DOI":"10.1016\/j.ejim.2017.09.005","article-title":"Chagas diseases: opportunities for internists","volume":"48","author":"Ramos","year":"2018","journal-title":"Eur J Intern Med"},{"key":"10.1016\/j.bbadis.2019.165591_bb0090","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1155\/2014\/401864","article-title":"Chagas\u2019 disease: pregnancy and congenital transmission","volume":"2014","author":"Cevallos","year":"2014","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.bbadis.2019.165591_bb0095","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.3389\/fmicb.2019.01250","article-title":"Trypanosoma cruzi infection at the maternal-fetal interface: implications of parasite load in the congenital transmission and challenges in the diagnosis of infected newborns","volume":"10","author":"Bustos","year":"2019","journal-title":"Front. Microbiol."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0100","doi-asserted-by":"crossref","first-page":"478","DOI":"10.4269\/ajtmh.17-0516","article-title":"Congenital transmission of Trypanosoma cruzi in Argentina, Honduras, and Mexico: an observational prospective study","volume":"98","author":"Buekens","year":"2018","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"Suppl. 2","key":"10.1016\/j.bbadis.2019.165591_bb0105","first-page":"33","article-title":"Congenital Chagas disease in Cordoba, Argentina: epidemiological, clinical, diagnostic, and therapeutic aspects. Experience of 30 years of follow up","volume":"38","author":"Moya","year":"2005","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0110","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1590\/S0037-86822009000200002","article-title":"Mother-child transmission of Chagas disease: could coinfection with human immunodeficiency virus increase the risk?","volume":"42","author":"Scapellato","year":"2009","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0115","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.bjid.2012.06.008","article-title":"Two cases of mother-to-child transmission of HIV and Trypanosoma cruzi in Argentina- ClinicalKey","volume":"16","author":"Agosti","year":"2012","journal-title":"Braz. J. Infect. Dis."},{"key":"10.1016\/j.bbadis.2019.165591_bb0120","series-title":"Recent Advances in Research on the Human Placenta, InTech","first-page":"127","article-title":"Placental infection by Trypanosoma cruzi, the causal agent of congenital Chagas disease","author":"Diaz-Luj\u00e1n","year":"2012"},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0125","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1093\/cid\/cix277","article-title":"Toward improving early diagnosis of congenital Chagas disease in an endemic setting","volume":"65","author":"Messenger","year":"2017","journal-title":"Clin. Infect. Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0130","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/QCO.0000000000000478","article-title":"Congenital Chagas disease: current diagnostics, limitations and future perspectives","volume":"31","author":"Messenger","year":"2018","journal-title":"Curr. Opin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0135","first-page":"249","article-title":"Evaluation of cardiac function by radioisotopic angiography, in patients with chronic Chagas cardiopathy","volume":"45","author":"Kuschnir","year":"1985","journal-title":"Arq. Bras. Cardiol."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0140","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1590\/S0066-782X2011000600002","article-title":"I Latin American guidelines for the diagnosis and treatment of Chagas\u2019 heart disease: executive summary","volume":"96","author":"Andrade","year":"2011","journal-title":"Arq. Bras. Cardiol."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0145","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jacc.2013.05.046","article-title":"Chagas disease: an overview of clinical and epidemiological aspects","volume":"62","author":"Nunes","year":"2013","journal-title":"J. Am. Coll. Cardiol."},{"issue":"Suppl. 1","key":"10.1016\/j.bbadis.2019.165591_bb0150","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1590\/S0074-02762009000900017","article-title":"Diagnosis of Chagas disease: what has been achieved? What remains to be done with regard to diagnosis and follow up studies?","volume":"104","author":"Gomes","year":"2009","journal-title":"Mem. Inst. Oswaldo Cruz"},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0155","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005779","article-title":"Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples","volume":"11","author":"Besuschio","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0160","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1093\/infdis\/jiy562","article-title":"Trypomastigote excretory secretory antigen blot is associated with Trypanosoma cruzi load and detects congenital T. cruzi infection in neonates, using anti-shed acute phase antigen immunoglobulin M","volume":"219","author":"Noazin","year":"2019","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbadis.2019.165591_bb0165","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.actatropica.2015.03.026","article-title":"Diagnosis of congenital Trypanosoma cruzi infection: a serologic test using shed acute phase antigen (SAPA) in mother-child binomial samples","volume":"147","author":"Volta","year":"2015","journal-title":"Acta Trop."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005501","article-title":"Rapid diagnostic tests duo as alternative to conventional serological assays for conclusive Chagas disease diagnosis","volume":"11","author":"Eguez","year":"2017","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0175","doi-asserted-by":"crossref","first-page":"2676","DOI":"10.4049\/jimmunol.151.5.2676","article-title":"Trypanosoma cruzi: immunity-induced in mice and rats by trypomastigote excretory-secretory antigens and identification of a peptide sequence containing a T cell epitope with protective activity","volume":"151","author":"Taibi","year":"1993","journal-title":"J. Immunol."},{"issue":"10180","key":"10.1016\/j.bbadis.2019.165591_bb0180","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1016\/S0140-6736(19)30288-0","article-title":"Guidelines for the diagnosis and treatment of Chagas disease","volume":"393","author":"Pereiro","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.bbadis.2019.165591_bb0185","first-page":"1","article-title":"Chagas disease diagnostic applications: present knowledge and future steps","volume":"97","author":"Balouz","year":"2017","journal-title":"Adv. Parasitol."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0190","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1645\/GE-549R.1","article-title":"Early diagnosis of congenital Trypanosoma cruzi infection using PCR, hemoculture, and capillary concentration, as compared with delayed serology","volume":"91","author":"Mora","year":"2005","journal-title":"J. Parasitol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0195","doi-asserted-by":"crossref","first-page":"100","DOI":"10.2307\/3275421","article-title":"A method for concentrating hemoflagellates","volume":"48","author":"Strout","year":"1962","journal-title":"J. Parasitol."},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0200","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002476","article-title":"How to improve the early diagnosis of Trypanosoma cruzi infection: relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children","volume":"7","author":"Bua","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0205","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.diagmicrobio.2017.06.012","article-title":"Rapid detection of Trypanosoma cruzi by colorimetric loop-mediated isothermal amplification (LAMP): a potential novel tool for the detection of congenital Chagas infection","volume":"89","author":"Rivero","year":"2017","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003211","article-title":"Use of a novel Chagas urine nanoparticle test (chunap) for diagnosis of congenital Chagas disease","volume":"8","author":"Castro-Sesquen","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002304","article-title":"Achievements and challenges upon the implementation of a program for national control of congenital Chagas in Bolivia: results 2004-2009","volume":"7","author":"Alonso-Vega","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0220","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.4269\/ajtmh.16-0761","article-title":"Experimental and clinical treatment of Chagas disease: a review","volume":"97","author":"Sales Junior","year":"2017","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0225","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003465","article-title":"Follow-up of an asymptomatic Chagas disease population of children after treatment with nifurtimox (Lampit) in a sylvatic endemic transmission area of Colombia","volume":"9","author":"Bianchi","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0230","doi-asserted-by":"crossref","first-page":"4518","DOI":"10.1128\/AAC.00227-13","article-title":"Evaluation of nifurtimox treatment of chronic Chagas Disease by means of several parasitological methods","volume":"57","author":"Mu\u00f1oz","year":"2013","journal-title":"Antimicrob. Agents Chemother."},{"issue":"9039","key":"10.1016\/j.bbadis.2019.165591_bb0235","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1016\/S0140-6736(96)04128-1","article-title":"Randomised trial of efficacy of Benznidazole in treatment of early Trypanosoma cruzi infection","volume":"348","author":"de Andrade","year":"1996","journal-title":"Lancet"},{"issue":"3\u20134","key":"10.1016\/j.bbadis.2019.165591_bb0240","first-page":"69","article-title":"Current prospects of specific treatment of Chagas\u2019 disease","volume":"51","author":"Coura","year":"1996","journal-title":"Bol. Chil. Parasitol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actatropica.2015.12.017","article-title":"Current drug therapy and pharmaceutical challenges for Chagas disease","volume":"156","author":"Bermudez","year":"2016","journal-title":"Acta Trop."},{"key":"10.1016\/j.bbadis.2019.165591_bb0250","author":"Centers for Disease Control and Prevention"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0255","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s40506-018-0170-z","article-title":"Treatment of Chagas disease in the United States","volume":"10","author":"Meymandi","year":"2018","journal-title":"Curr. Treat. Options Infect. Dis."},{"key":"10.1016\/j.bbadis.2019.165591_bb0260","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.actatropica.2017.07.004","article-title":"Prevention of congenital Chagas disease by Benznidazole treatment in reproductive-age women. An observational study","volume":"174","author":"Alvarez","year":"2017","journal-title":"Acta Trop."},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003312","article-title":"Trypanocide treatment of women infected with Trypanosoma cruzi and its effect on preventing congenital Chagas","volume":"8","author":"Fabbro","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0270","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1093\/infdis\/jix087","article-title":"Treatment of infected women of childbearing age prevents congenital Trypanosoma cruzi infection by eliminating the parasitemia detected by PCR","volume":"215","author":"Murcia","year":"2017","journal-title":"J. Infect. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0275","doi-asserted-by":"crossref","first-page":"2492","DOI":"10.1128\/AAC.02506-15","article-title":"Benznidazole extended-release tablets for improved treatment of Chagas disease: preclinical pharmacokinetic study","volume":"60","author":"Davan\u00e7o","year":"2016","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.bbadis.2019.165591_bb0280","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.tmaid.2018.04.011","article-title":"Congenital Chagas disease in a non-endemic area: results from a control programme in Bergamo province, Northern Italy","volume":"25","author":"Rodari","year":"2018","journal-title":"Travel Med. Infect. Dis."},{"key":"10.1016\/j.bbadis.2019.165591_bb0285","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/B978-0-12-385863-4.00002-2","article-title":"Acute and congenital Chagas disease","volume":"75","author":"Bern","year":"2011","journal-title":"Adv. Parasitol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0290","first-page":"74","article-title":"Nifurtimox chemotherapy: collateral effects in treated Trypanosoma cruzi infected patients","volume":"25","author":"Murcia","year":"2012","journal-title":"Rev. Esp. Quimioter."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0295","doi-asserted-by":"crossref","first-page":"360","DOI":"10.3390\/nu7010360","article-title":"Placental adaptations in growth restriction","volume":"7","author":"Zhang","year":"2015","journal-title":"Nutrients"},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0300","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1016\/j.chom.2017.04.007","article-title":"Microbial vertical transmission during human pregnancy","volume":"21","author":"Arora","year":"2017","journal-title":"Cell Host Microbe"},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0305","first-page":"225","article-title":"Parasites and fungi as a threat for prenatal and postnatal human development","volume":"60","author":"Blaszkowska","year":"2014","journal-title":"Ann. Parasitol."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0310","doi-asserted-by":"crossref","first-page":"319","DOI":"10.4269\/ajtmh.2000.62.319","article-title":"Immunohistochemical characterization of the inflammatory infiltrate in placental Chagas\u2019 disease: a qualitative and quantitative analysis","volume":"62","author":"Altemani","year":"2000","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"Suppl. 2","key":"10.1016\/j.bbadis.2019.165591_bb0315","first-page":"84","article-title":"Placental lesions in human Trypanosoma cruzi infection","volume":"38","author":"Fernandez-Aguilar","year":"2005","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0320","doi-asserted-by":"crossref","first-page":"201","DOI":"10.4269\/ajtmh.2004.70.201","article-title":"Maternal Trypanosoma cruzi infection, pregnancy outcome, morbidity, and mortality of congenitally infected and non-infected newborns in Bolivia","volume":"70","author":"Torrico","year":"2004","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0325","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1053\/j.semperi.2017.07.012","article-title":"Preterm prelabor rupture of the membranes: a disease of the fetal membranes","volume":"41","author":"Menon","year":"2017","journal-title":"Semin. Perinatol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0330","doi-asserted-by":"crossref","first-page":"38","DOI":"10.4269\/ajtmh.1981.30.38","article-title":"Pneumonitis in congenital Chagas' disease. A study of ten cases","volume":"30","author":"Bittencourt","year":"1981","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0335","doi-asserted-by":"crossref","first-page":"570","DOI":"10.1111\/apm.12847","article-title":"Defense and infection of the human placenta","volume":"126","author":"Heerema-McKenney","year":"2018","journal-title":"APMIS"},{"key":"10.1016\/j.bbadis.2019.165591_bb0340","doi-asserted-by":"crossref","first-page":"614820","DOI":"10.1155\/2012\/614820","article-title":"Mechanism of Trypanosoma cruzi placenta invasion and infection: the use of human chorionic villi explants","volume":"2012","author":"Fretes","year":"2012","journal-title":"J. Trop. Med."},{"key":"10.1016\/j.bbadis.2019.165591_bb0345","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.actatropica.2016.09.021","article-title":"Role of placental barrier integrity in infection by Trypanosoma cruzi","volume":"164","author":"Diaz-Lujan","year":"2016","journal-title":"Acta Trop."},{"key":"10.1016\/j.bbadis.2019.165591_bb0350","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.micpath.2016.08.022","article-title":"A local innate immune response against Trypanosoma cruzi in the human placenta: the epithelial turnover of the trophoblast","volume":"99","author":"Liempi","year":"2016","journal-title":"Microb. Pathog."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0355","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1016\/j.jri.2010.12.003","article-title":"The role of the Nod-like receptor family in trophoblast innate immune responses","volume":"88","author":"Abrahams","year":"2011","journal-title":"J. Reprod. Immunol."},{"issue":"1 Suppl","key":"10.1016\/j.bbadis.2019.165591_bb0360","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1016\/j.ajog.2016.03.001","article-title":"Placental origins of adverse pregnancy outcomes: potential molecular targets: an executive workshop summary of the Eunice Kennedy Shriver national institute of child health and human development","volume":"215","author":"Ilekis","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0365","doi-asserted-by":"crossref","DOI":"10.1111\/aji.12852","article-title":"Nitric oxide synthase and oxidative-nitrosative stress play a key role in placental infection by Trypanosoma cruzi","volume":"80","author":"Triquell","year":"2018","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0370","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.placenta.2017.10.005","article-title":"Toll-like receptor-2 mediates local innate immune response against Trypanosoma cruzi in ex vivo infected human placental chorionic villi explants","volume":"60","author":"Castillo","year":"2017","journal-title":"Placenta"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0375","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.actatropica.2012.08.001","article-title":"Presence of Trypanosoma cruzi in pregnant women and typing of lineages in congenital cases","volume":"124","author":"Ortiz","year":"2012","journal-title":"Acta Trop."},{"issue":"19","key":"10.1016\/j.bbadis.2019.165591_bb0380","first-page":"30367","article-title":"Phylogenetic analysis of Trypanosoma cruzi from pregnant women and newborns from Argentina, Honduras, and Mexico suggests an association of parasite haplotypes with congenital transmission of the parasite","volume":"S1525-1578","author":"Herrera","year":"2019","journal-title":"J. Mol. Diagn."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0385","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1016\/j.meegid.2008.12.008","article-title":"Congenital Chagas disease involves Trypanosoma cruzi sub-lineage IId in the northwestern province of Salta, Argentina","volume":"9","author":"Corrales","year":"2009","journal-title":"Infect. Genet. Evol."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0390","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003458","article-title":"Deep sequencing of the Trypanosoma cruzi GP63 surface proteases reveals diversity and diversifying selection among chronic and congenital Chagas disease patients","volume":"9","author":"Llewellyn","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0395","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.diagmicrobio.2009.04.010","article-title":"Molecular diagnosis and treatment monitoring of congenital transmission of Trypanosoma cruzi to twins of a triplet delivery","volume":"65","author":"Burgos","year":"2009","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0400","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.actatropica.2011.10.018","article-title":"Congenital parasitic infections: a review","volume":"121","author":"Carlier","year":"2012","journal-title":"Acta Trop."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0405","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1590\/S0036-46651992000500006","article-title":"Possible risk factors for vertical transmission of Chagas\u2019 disease","volume":"34","author":"Bittencourt","year":"1992","journal-title":"Rev. Inst. Med. Trop. Sao Paulo"},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0410","doi-asserted-by":"crossref","first-page":"569","DOI":"10.4269\/ajtmh.2011.10-0015","article-title":"Chagas disease: increased parasitemia during pregnancy detected by hemoculture","volume":"84","author":"Siriano Lda","year":"2011","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0415","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/aji.12289","article-title":"Understanding the complexity of the immune system during pregnancy","volume":"72","author":"Racicot","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0420","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0119527","article-title":"Trypanosoma cruzi-infected pregnant women without vector exposure have higher parasitemia levels: implications for congenital transmission risk","volume":"10","author":"Rendell","year":"2015","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0425","doi-asserted-by":"crossref","first-page":"e668","DOI":"10.1542\/peds.2004-1732","article-title":"High prevalence of congenital Trypanosoma cruzi infection and family clustering in Salta, Argentina","volume":"115","author":"Sanchez Negrette","year":"2005","journal-title":"Pediatrics"},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0430","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1590\/S0037-86822005000100010","article-title":"Chagas\u2019 disease: study of congenital transmission in cases of acute maternal infection","volume":"38","author":"Moretti","year":"2005","journal-title":"Rev. Soc. Bras. Med. Trop."},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0435","doi-asserted-by":"crossref","first-page":"1274","DOI":"10.1086\/382511","article-title":"Congenital transmission of Trypanosoma cruzi is associated with maternal enhanced parasitemia and decreased production of interferon-gamma in response to parasite antigens","volume":"189","author":"Hermann","year":"2004","journal-title":"J. Infect. Dis."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0440","doi-asserted-by":"crossref","first-page":"499","DOI":"10.4269\/ajtmh.2008.78.499","article-title":"Soluble tumor necrosis factor (TNF) receptors (sTNF-R1 and -R2) in pregnant women chronically infected with Trypanosoma cruzi and their children","volume":"78","author":"Garcia","year":"2008","journal-title":"Am. J. Trop. Med. Hyg."},{"issue":"12","key":"10.1016\/j.bbadis.2019.165591_bb0445","doi-asserted-by":"crossref","first-page":"1498","DOI":"10.1111\/j.1365-3156.2007.01958.x","article-title":"Risk factors and consequences of congenital Chagas disease in Yacuiba, south Bolivia","volume":"12","author":"Salas","year":"2007","journal-title":"Tropical Med. Int. Health"},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0450","doi-asserted-by":"crossref","first-page":"4596","DOI":"10.4049\/jimmunol.1502504","article-title":"Serum cytokines as biomarkers of early Trypanosoma cruzi infection by congenital exposure","volume":"196","author":"Volta","year":"2016","journal-title":"J. Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0455","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1111\/j.1365-2567.2009.03194.x","article-title":"Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi","volume":"129","author":"Hermann","year":"2010","journal-title":"Immunology"},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0460","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1161\/CIRCULATIONAHA.106.624296","article-title":"Pathogenesis of chronic Chagas heart disease","volume":"115","author":"Marin-Neto","year":"2007","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0465","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1111\/j.1365-3024.2009.01108.x","article-title":"The role of parasite persistence in pathogenesis of Chagas heart disease","volume":"31","author":"Gutierrez","year":"2009","journal-title":"Parasite Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0470","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1128\/CMR.00063-10","article-title":"Pathogenesis of Chagas\u2019 disease: parasite persistence and autoimmunity","volume":"24","author":"Teixeira","year":"2011","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.bbadis.2019.165591_bb0475","doi-asserted-by":"crossref","first-page":"1842","DOI":"10.3389\/fimmu.2018.01842","article-title":"Autoimmunity in chronic Chagas disease: a road of multiple pathways to cardiomyopathy?","volume":"9","author":"De Bona","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0480","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.2741\/1624","article-title":"Mitochondrial disorders in chagasic cardiomyopathy","volume":"10","author":"Garg","year":"2005","journal-title":"Front. Biosci."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0485","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1590\/S0001-37652005000400009","article-title":"An overview of chagasic cardiomyopathy: pathogenic importance of oxidative stress","volume":"77","author":"Zacks","year":"2005","journal-title":"An. Acad. Bras. Cienc."},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0490","doi-asserted-by":"crossref","first-page":"1414","DOI":"10.1016\/j.freeradbiomed.2009.08.008","article-title":"Trypanosoma cruzi infection disturbs mitochondrial membrane potential and ROS production rate in cardiomyocytes","volume":"47","author":"Gupta","year":"2009","journal-title":"Free Radic. Biol. Med."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0495","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1007\/s10863-008-9184-4","article-title":"Mitochondrial generation of reactive oxygen species is enhanced at the Q(o) site of the complex III in the myocardium of Trypanosoma cruzi-infected mice: beneficial effects of an antioxidant","volume":"40","author":"Wen","year":"2008","journal-title":"J. Bioenerg. Biomembr."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0500","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1089\/ars.2008.2418","article-title":"Mitochondrial complex III defects contribute to inefficient respiration and ATP synthesis in the myocardium of Trypanosoma cruzi-infected mice","volume":"12","author":"Wen","year":"2010","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2019.165591_bb0505","doi-asserted-by":"crossref","unstructured":"S. Gupta, J.J. Wen, N.J. Garg, Oxidative stress in Chagas disease, Interdiscip. Perspect. Infect. Dis. 2009(190354) (2009) 8.","DOI":"10.1155\/2009\/190354"},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0510","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1007\/s40588-018-0081-2","article-title":"Pathogenesis of chronic Chagas disease: macrophages, mitochondria, and oxidative Stress","volume":"5","author":"Lopez","year":"2018","journal-title":"Curr. Clin. Microbiol. Rep."},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0515","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1016\/j.freeradbiomed.2004.08.018","article-title":"Oxidative damage during chagasic cardiomyopathy development: role of mitochondrial oxidant release and inefficient antioxidant defense","volume":"37","author":"Wen","year":"2004","journal-title":"Free Radic. Biol. Med."},{"issue":"10\u201311","key":"10.1016\/j.bbadis.2019.165591_bb0520","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1016\/j.micinf.2008.06.013","article-title":"Tissue-specific oxidative imbalance and mitochondrial dysfunction during Trypanosoma cruzi infection in mice","volume":"10","author":"Wen","year":"2008","journal-title":"Microbes Infect."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0525","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028449","article-title":"Cardiac-oxidized antigens are targets of immune recognition by antibodies and potential molecular determinants in Chagas disease pathogenesis","volume":"7","author":"Dhiman","year":"2012","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0530","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/j.freeradbiomed.2006.04.009","article-title":"Increased oxidative stress is correlated with mitochondrial dysfunction in chagasic patients","volume":"41","author":"Wen","year":"2006","journal-title":"Free Radic. Biol. Med."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0535","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.ijcard.2006.04.046","article-title":"Oxidative stress in chronic cardiopathy associated with Chagas disease","volume":"116","author":"de Oliveira","year":"2007","journal-title":"Int. J. Cardiol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0540","doi-asserted-by":"crossref","first-page":"728","DOI":"10.2353\/ajpath.2008.080047","article-title":"Enhanced nitrosative stress during Trypanosoma cruzi infection causes nitrotyrosine modification of host proteins: implications in Chagas\u2019 disease","volume":"173","author":"Dhiman","year":"2008","journal-title":"Am. J. Pathol."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0545","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1128\/CVI.00019-09","article-title":"Increased myeloperoxidase activity and protein nitration are indicators of inflammation in patients with Chagas\u2019 disease","volume":"16","author":"Dhiman","year":"2009","journal-title":"Clin. Vaccine Immunol."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0550","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.2353\/ajpath.2006.060475","article-title":"Phenyl-alpha-tert-butyl nitrone reverses mitochondrial decay in acute Chagas\u2019 disease","volume":"169","author":"Wen","year":"2006","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0555","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0020-7519(02)00283-7","article-title":"Severity of chronic Chagas disease is associated with cytokine\/antioxidant imbalance in chronically infected individuals","volume":"33","author":"Perez-Fuentes","year":"2003","journal-title":"Int. J. Parasitol."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0560","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1089\/ars.2016.6831","article-title":"Inhibition of NFE2L2-antioxidant response element pathway by mitochondrial reactive oxygen species contributes to development of cardiomyopathy and left ventricular dysfunction in Chagas Disease","volume":"27","author":"Wen","year":"2017","journal-title":"Antioxid. Redox Signal."},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0565","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005954","article-title":"SIRT1-PGC1alpha-NFkappaB pathway of oxidative and inflammatory stress during Trypanosoma cruzi infection: benefits of SIRT1-targeted therapy in improving heart function in Chagas disease","volume":"12","author":"Wan","year":"2016","journal-title":"PLoS Pathog."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0570","doi-asserted-by":"crossref","DOI":"10.1161\/JAHA.113.000302","article-title":"MnSOD tg mice control myocardial inflammatory and oxidative stress and remodeling responses elicited in chronic Chagas disease","volume":"2","author":"Dhiman","year":"2013","journal-title":"J. Am. Heart Assoc."},{"issue":"15","key":"10.1016\/j.bbadis.2019.165591_bb0575","doi-asserted-by":"crossref","first-page":"11596","DOI":"10.1074\/jbc.M109.076984","article-title":"Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes","volume":"285","author":"Ba","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0580","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1159\/000451055","article-title":"Gene expression profiling and functional characterization of macrophages in response to circulatory microparticles produced during Trypanosoma cruzi infection and Chagas disease","volume":"9","author":"Chowdhury","year":"2017","journal-title":"J. Innate Immun."},{"key":"10.1016\/j.bbadis.2019.165591_bb0585","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1146\/annurev-pathol-020117-043711","article-title":"Pathology and pathogenesis of Chagas heart disease","volume":"14","author":"Bonney","year":"2019","journal-title":"Annu. Rev. Pathol."},{"issue":"Article ID: 489758","key":"10.1016\/j.bbadis.2019.165591_bb0590","first-page":"8","article-title":"Experimental vaccines against Chagas disease: a journey through history","volume":"2015","author":"Rodriguez-Morales","year":"2015","journal-title":"J Immunol Res"},{"key":"10.1016\/j.bbadis.2019.165591_bb0595","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/B978-0-12-385863-4.00006-X","article-title":"Vaccine development against Trypanosoma cruzi and Chagas disease","volume":"75","author":"Vazquez-Chagoyan","year":"2011","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0600","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s13071-015-0738-0","article-title":"Prophylactic and therapeutic DNA vaccines against Chagas disease","volume":"8","author":"Arce-Fonseca","year":"2015","journal-title":"Parasit. Vectors"},{"issue":"42","key":"10.1016\/j.bbadis.2019.165591_bb0605","doi-asserted-by":"crossref","first-page":"6290","DOI":"10.1016\/j.vaccine.2018.09.004","article-title":"Examination of antigenic proteins of Trypanosoma cruzi to fabricate an epitope-based subunit vaccine by exploiting epitope mapping mechanism","volume":"36","author":"Khatoon","year":"2018","journal-title":"Vaccine"},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0610","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0130562","article-title":"Therapeutic efficacy of a subunit vaccine in controlling chronic Trypanosoma cruzi infection and Chagas disease is enhanced by glutathione peroxidase over-expression","volume":"10","author":"Gupta","year":"2015","journal-title":"PLoS One"},{"issue":"001","key":"10.1016\/j.bbadis.2019.165591_bb0615","first-page":"8","article-title":"Strategy for the development of vaccines against Chagas Disease","volume":"1","author":"Ma","year":"2015","journal-title":"HSOA J. Vaccines Res. Vaccin."},{"issue":"5733","key":"10.1016\/j.bbadis.2019.165591_bb0620","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1126\/science.1112631","article-title":"The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease","volume":"309","author":"El-Sayed","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbadis.2019.165591_bb0625","doi-asserted-by":"crossref","unstructured":"M.S. Cardoso, J.L. Reis-Cunha, D.C. Bartholomeu, Evasion of the immune response by Trypanosoma cruzi during acute infection, Front. Immunol. 6(659) (2015) 15.","DOI":"10.3389\/fimmu.2015.00659"},{"issue":"12","key":"10.1016\/j.bbadis.2019.165591_bb0630","doi-asserted-by":"crossref","first-page":"6120","DOI":"10.4049\/jimmunol.159.12.6120","article-title":"Identification of Trypanosoma cruzi trans-sialidase family members as targets of protective CD8+ TC1 responses","volume":"159","author":"Wizel","year":"1997","journal-title":"J. Immunol."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0635","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1172\/JCI3835","article-title":"Human infection with Trypanosoma cruzi induces parasite antigen-specific cytotoxic T lymphocyte responses","volume":"102","author":"Wizel","year":"1998","journal-title":"J. Clin. Invest."},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0640","doi-asserted-by":"crossref","first-page":"2973","DOI":"10.1128\/iai.62.7.2973-2978.1994","article-title":"Sera from chronic Chagasic patients and rodents infected with Trypanosoma cruzi inhibit trans-sialidase by recognizing its amino-terminal and catalytic domain","volume":"62","author":"Pereira-Chioccola","year":"1994","journal-title":"Infect. Immun."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0645","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1046\/j.1365-3024.2000.00260.x","article-title":"Chagasic patients develop a type 1 immune response to Trypanosoma cruzi trans-sialidase","volume":"22","author":"Ribeirao","year":"2000","journal-title":"Parasite Immunol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0650","first-page":"1","article-title":"The identification and molecular characterization of Trypanosoma cruzi amastigote surface protein-1, a member of the trans-sialidase gene super-family","volume":"86","author":"Santos","year":"1997","journal-title":"Mol. Biochem. Parasitol."},{"issue":"1\u20132","key":"10.1016\/j.bbadis.2019.165591_bb0655","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/S0166-6851(97)00088-1","article-title":"Molecular cloning of the gene encoding the 83 kDa amastigote surface protein and its identification as a member of the Trypanosoma cruzi sialidase superfamily","volume":"88","author":"Low","year":"1997","journal-title":"Mol. Biochem. Parasitol."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0660","doi-asserted-by":"crossref","first-page":"2744","DOI":"10.1128\/IAI.71.5.2744-2757.2003","article-title":"Immunization with cDNA expressed by amastigotes of Trypanosoma cruzi elicits protective immune response against experimental infection","volume":"71","author":"Boscardin","year":"2003","journal-title":"Infect. Immun."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0665","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.4049\/jimmunol.160.4.1817","article-title":"Amastigote surface proteins of Trypanosoma cruzi are targets for CD8+ CTL","volume":"160","author":"Low","year":"1998","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0670","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0061795","article-title":"Vaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infection","volume":"8","author":"Barbosa","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2019.165591_bb0675","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cyto.2018.07.017","article-title":"Therapeutic effects of vaccine derived from amastigote surface protein-2 (ASP-2) against Chagas disease in mouse liver","volume":"113","author":"Ribeiro","year":"2019","journal-title":"Cytokine"},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0680","doi-asserted-by":"crossref","first-page":"4072","DOI":"10.1128\/iai.62.9.4072-4074.1994","article-title":"Humoral immune response to the Trypanosoma cruzi complement regulatory protein as an indicator of parasitologic clearance in human Chagas\u2019 disease","volume":"62","author":"Norris","year":"1994","journal-title":"Infect. Immun."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0685","doi-asserted-by":"crossref","first-page":"4986","DOI":"10.1128\/IAI.68.9.4986-4991.2000","article-title":"DNA-based immunization with Trypanosoma cruzi complement regulatory protein elicits complement lytic antibodies and confers protection against Trypanosoma cruzi infection","volume":"68","author":"Sepulveda","year":"2000","journal-title":"Infect. Immun."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0690","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1016\/j.micinf.2005.01.001","article-title":"Identification of multiple HLA-A*0201-restricted cruzipain and FL-160 CD8+ epitopes recognized by T cells from chronically Trypanosoma cruzi-infected patients","volume":"7","author":"Fonseca","year":"2005","journal-title":"Microbes Infect."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0695","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0124832","article-title":"Cruzipain activates latent TGF-\u03b2 from host cells during T. cruzi invasion","volume":"10","author":"Ferr\u00e3o","year":"2015","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0700","doi-asserted-by":"crossref","first-page":"2057","DOI":"10.1093\/emboj\/18.8.2057","article-title":"Flagellar protein localization mediated by a calcium-myristoyl\/palmitoyl switch mechanism","volume":"18","author":"Godsel","year":"1999","journal-title":"EMBO J."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0705","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1016\/j.xphs.2017.12.014","article-title":"Characterization and stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a candidate antigen for a therapeutic vaccine against Chagas disease","volume":"107","author":"Biter","year":"2018","journal-title":"J. Pharm. Sci."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0710","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1006\/expr.1993.1100","article-title":"Trypanosoma cruzi: antibody production and T cell response induced by stage-specific surface glycoproteins purified from metacyclic trypomastigotes","volume":"77","author":"Yoshida","year":"1993","journal-title":"Exp. Parasitol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0715","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0166-6851(94)90124-4","article-title":"Cloning and characterization of a gene for the stage-specific 82-kDa surface antigen of metacyclic trypomastigotes of Trypanosoma cruzi","volume":"65","author":"Araya","year":"1994","journal-title":"Mol. Biochem. Parasitol."},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0720","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1128\/iai.61.10.4196-4201.1993","article-title":"Characterization of a cDNA clone encoding the carboxy-terminal domain of a 90-kilodalton surface antigen of Trypanosoma cruzi metacyclic trypomastigotes","volume":"61","author":"Franco","year":"1993","journal-title":"Infect. Immun."},{"issue":"9","key":"10.1016\/j.bbadis.2019.165591_bb0725","doi-asserted-by":"crossref","first-page":"e00302","DOI":"10.1128\/IAI.00302-17","article-title":"Inhibition of host cell lysosome spreading by Trypanosoma cruzi metacyclic stage-specific surface molecule gp90 downregulates parasite invasion","volume":"85","author":"Rodrigues","year":"2017","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0730","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0165-2478(99)00146-7","article-title":"The humoral immune response to the kinetoplastid membrane protein-11 in patients with American leishmaniasis and Chagas disease: prevalence of IgG subclasses and mapping of epitopes","volume":"70","author":"Trujillo","year":"1999","journal-title":"Immunol. Lett."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0735","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0161-5890(01)00059-1","article-title":"The immunization of A2\/K(b) transgenic mice with the KMP11-HSP70 fusion protein induces CTL response against human cells expressing the T. cruzi KMP11 antigen: identification of A2-restricted epitopes","volume":"38","author":"Maranon","year":"2001","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0740","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1186\/1471-2334-9-186","article-title":"Characterising the KMP-11 and HSP-70 recombinant antigens\u2019 humoral immune response profile in chagasic patients","volume":"9","author":"Flechas","year":"2009","journal-title":"BMC Infect. Dis."},{"issue":"21\u201322","key":"10.1016\/j.bbadis.2019.165591_bb0745","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1016\/S0264-410X(03)00121-X","article-title":"Genetic immunization with LYT1 or a pool of trans-sialidase genes protects mice from lethal Trypanosoma cruzi infection","volume":"21","author":"Fralish","year":"2003","journal-title":"Vaccine"},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0750","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1046\/j.1365-3024.2002.00479.x","article-title":"Paraflagellar rod protein-specific CD8+ cytotoxic T lymphocytes target Trypanosoma cruzi-infected host cells","volume":"24","author":"Wrightsman","year":"2002","journal-title":"Parasite Immunol."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0755","doi-asserted-by":"crossref","first-page":"3165","DOI":"10.1128\/IAI.71.6.3165-3171.2003","article-title":"Humoral and cellular immune responses to Trypanosoma cruzi-derived paraflagellar rod proteins in patients with Chagas\u2019 disease","volume":"71","author":"Michailowsky","year":"2003","journal-title":"Infect. Immun."},{"issue":"3\u20134","key":"10.1016\/j.bbadis.2019.165591_bb0760","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.molimm.2012.05.021","article-title":"Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients","volume":"52","author":"Egui","year":"2012","journal-title":"Mol. Immunol."},{"issue":"49\u201350","key":"10.1016\/j.bbadis.2019.165591_bb0765","doi-asserted-by":"crossref","first-page":"7046","DOI":"10.1016\/j.vaccine.2006.07.006","article-title":"The genetic immunization with paraflagellar rod protein-2 fused to the HSP70 confers protection against late Trypanosoma cruzi infection","volume":"24","author":"Morell","year":"2006","journal-title":"Vaccine"},{"issue":"7","key":"10.1016\/j.bbadis.2019.165591_bb0770","doi-asserted-by":"crossref","first-page":"3471","DOI":"10.4049\/jimmunol.160.7.3471","article-title":"Trypanosoma cruzi: Tc52 released protein-induced increased expression of nitric oxide synthase and nitric oxide production by macrophages","volume":"160","author":"Fernandez-Gomez","year":"1998","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0775","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/s41541-019-0107-7","article-title":"A prophylactic \u03b1-Gal-based glycovaccine effectively protects against murine acute Chagas disease","volume":"4","author":"Portillo","year":"2019","journal-title":"NPJ Vaccines"},{"issue":"10","key":"10.1016\/j.bbadis.2019.165591_bb0780","doi-asserted-by":"crossref","first-page":"5547","DOI":"10.1128\/IAI.70.10.5547-5555.2002","article-title":"Genetic immunization elicits antigen-specific protective immune responses and decreases disease severity in Trypanosoma cruzi infection","volume":"70","author":"Garg","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbadis.2019.165591_bb0785","unstructured":"N.J. Garg, R.L. Tarleton, Elicitation of protective cellular and humoral immune responses to Trypanosoma cruzi infection using DNA vaccines can be augmented with cytokines., Proceedings 10th International Congress of Immunology, Bologna, Italy: Monduzzi Editore, International Proceedings Division, \u00a91998., New Delhi, India, 1998, pp. 1421-1426."},{"key":"10.1016\/j.bbadis.2019.165591_bb0790","article-title":"Immunity and vaccine development efforts against Trypanosoma cruzi","volume":"105168","author":"Rios","year":"2019","journal-title":"Acta Trop."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0795","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1093\/infdis\/jiu418","article-title":"From genome screening to creation of vaccine against Trypanosoma cruzi by use of immunoinformatics","volume":"211","author":"Teh-Poot","year":"2015","journal-title":"J. Infect. Dis."},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0800","doi-asserted-by":"crossref","first-page":"6245","DOI":"10.1128\/IAI.72.11.6245-6254.2004","article-title":"Utility of the Trypanosoma cruzi sequence database for identification of potential vaccine candidates by in silico and in vitro screening","volume":"72","author":"Bhatia","year":"2004","journal-title":"Infect. Immun."},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0805","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1128\/CVI.00144-08","article-title":"Previously unrecognized vaccine candidates control Trypanosoma cruzi infection and immunopathology in mice","volume":"15","author":"Bhatia","year":"2008","journal-title":"Clin. Vaccine Immunol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0810","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002018","article-title":"Antigenicity and diagnostic potential of vaccine candidates in human Chagas disease","volume":"7","author":"Gupta","year":"2013","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0815","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001050","article-title":"Testing the efficacy of a multi-component DNA-prime\/DNA-boost vaccine against Trypanosoma cruzi infection in dogs","volume":"5","author":"Aparicio-Burgos","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0820","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003625","article-title":"Immune protection against Trypanosoma cruzi induced by TcVac4 in a canine model","volume":"9","author":"Aparicio-Burgos","year":"2015","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0825","doi-asserted-by":"crossref","first-page":"e797","DOI":"10.1371\/journal.pntd.0000797","article-title":"Prophylactic efficacy of TcVac2 against Trypanosoma cruzi in mice","volume":"4","author":"Gupta","year":"2010","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"50","key":"10.1016\/j.bbadis.2019.165591_bb0830","doi-asserted-by":"crossref","first-page":"7179","DOI":"10.1016\/j.vaccine.2012.10.018","article-title":"Delivery of antigenic candidates by a DNA\/MVA heterologous approach elicits effector CD8+T cell mediated immunity against Trypanosoma cruzi","volume":"30","author":"Gupta","year":"2012","journal-title":"Vaccine"},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0835","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1086\/344234","article-title":"Prime-boost immunization with DNA and modified vaccinia virus ankara vectors expressing herpes simplex virus-2 glycoprotein D elicits greater specific antibody and cytokine responses than DNA vaccine alone","volume":"186","author":"Meseda","year":"2002","journal-title":"J. Infect. Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0840","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019644","article-title":"Dendritic cells exposed to MVA-based HIV-1 vaccine induce highly functional HIV-1-specific CD8(+) T cell responses in HIV-1-infected individuals","volume":"6","author":"Climent","year":"2011","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0845","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1297-9716-44-15","article-title":"Specific humoral and cellular immunity induced by Trypanosoma cruzi DNA immunization in a canine model","volume":"44","author":"Arce-Fonseca","year":"2013","journal-title":"Vet. Res."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0850","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1128\/IAI.72.1.46-53.2004","article-title":"Immunotherapy of Trypanosoma cruzi infection with DNA vaccines in mice","volume":"72","author":"Dumonteil","year":"2004","journal-title":"Infect. Immun."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0855","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1111\/j.1574-695X.2007.00251.x","article-title":"Comparative evaluation of therapeutic DNA vaccines against Trypanosoma cruzi in mice","volume":"50","author":"Sanchez-Burgos","year":"2007","journal-title":"FEMS Immunol. Med. Microbiol."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0860","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.imlet.2005.11.015","article-title":"Control of Trypanosoma cruzi infection and changes in T-cell populations induced by a therapeutic DNA vaccine in mice","volume":"103","author":"Zapata-Estrella","year":"2006","journal-title":"Immunol. Lett."},{"key":"10.1016\/j.bbadis.2019.165591_bb0865","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1196\/annals.1428.098","article-title":"Therapeutic DNA vaccine against Trypanosoma cruzi infection in dogs","volume":"1149","author":"Quijano-Hernandez","year":"2008","journal-title":"Ann. N. Y. Acad. Sci."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0870","first-page":"90520","article-title":"DNA vaccines against protozoan parasites: advances and challenges","volume":"2007","author":"Dumonteil","year":"2007","journal-title":"J. Biomed. Biotechnol."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0875","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1007\/s00436-008-0992-6","article-title":"Benznidazole therapy during acute phase of Chagas disease reduces parasite load but does not prevent chronic cardiac lesions","volume":"103","author":"Caldas","year":"2008","journal-title":"Parasitol. Res."},{"issue":"22","key":"10.1016\/j.bbadis.2019.165591_bb0880","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1016\/j.jacc.2010.02.030","article-title":"Phenyl-alpha-tert-butyl-nitrone and Benzonidazole treatment controlled the mitochondrial oxidative stress and evolution of cardiomyopathy in chronic chagasic rats","volume":"55","author":"Wen","year":"2010","journal-title":"J. Am. Coll. Cardiol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0885","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.exppara.2010.06.030","article-title":"Trypanosoma cruzi: effect of the absence of 5-lipoxygenase (5-LO)-derived leukotrienes on levels of cytokines, nitric oxide and iNOS expression in cardiac tissue in the acute phase of infection in mice","volume":"127","author":"Panis","year":"2011","journal-title":"Exp. Parasitol."},{"issue":"4","key":"10.1016\/j.bbadis.2019.165591_bb0890","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.jacbts.2016.04.005","article-title":"Chemotherapeutic efficacy of phosphodiesterase inhibitors in chagasic cardiomyopathy","volume":"1","author":"Wen","year":"2016","journal-title":"JACC Basic Transl. Sci."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0895","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1007065","article-title":"PARP1 depletion improves mitochondrial and heart function in Chagas disease: effects on POLG dependent mtDNA maintenance","volume":"14","author":"Wen","year":"2018","journal-title":"PLoS Pathog."},{"issue":"8","key":"10.1016\/j.bbadis.2019.165591_bb0900","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0135192","article-title":"Maternal antioxidant levels in pregnancy and risk of preeclampsia and small for gestational age birth: a systematic review and meta-analysis","volume":"10","author":"Cohen","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2019.165591_bb0905","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.placenta.2018.03.003","article-title":"Oxidative stress in placental pathology","volume":"69","author":"Schoots","year":"2018","journal-title":"Placenta"},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0910","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1089\/scd.2018.0194","article-title":"A free radical scavenger ameliorates teratogenic activity of a DNA hypomethylating hematological therapeutic","volume":"28","author":"Sobo\u010dan","year":"2019","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.bbadis.2019.165591_bb0915","doi-asserted-by":"crossref","unstructured":"A. Rumbold, E. Ota, C. Nagata, S. Shahrook, C.A. Crowther, Vitamin C supplementation in pregnancy, Cochrane Database of Systematic Reviews (9) (2015) CD004072.","DOI":"10.1002\/14651858.CD004072.pub3"},{"key":"10.1016\/j.bbadis.2019.165591_bb0920","doi-asserted-by":"crossref","unstructured":"A. Rumbold, E. Ota, H. Hori, C. Miyazaki, C.A. Crowther, Vitamin E supplementation in pregnancy, Cochrane Database of Systematic Reviews (9) (2015) CD004069.","DOI":"10.1002\/14651858.CD004069.pub3"},{"key":"10.1016\/j.bbadis.2019.165591_bb0925","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.phrs.2019.04.020","article-title":"Systematic review: Impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications\u2014are we ready for the clinic?","volume":"144","author":"Darby","year":"2019","journal-title":"Pharmacol. Res."},{"issue":"11","key":"10.1016\/j.bbadis.2019.165591_bb0930","doi-asserted-by":"crossref","first-page":"4896","DOI":"10.1128\/AAC.00537-10","article-title":"Tolerance of Benznidazole in treatment of Chagas\u2019 disease in adults","volume":"54","author":"Pinazo","year":"2010","journal-title":"Antimicrob. Agents Chemother."},{"issue":"6","key":"10.1016\/j.bbadis.2019.165591_bb0935","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1600-0897.2010.00836.x","article-title":"The immune system in pregnancy: a unique complexity","volume":"63","author":"Mor","year":"2010","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0940","series-title":"Immunology of Pregnancy, 2015, pp","author":"Robertson","year":"1835"},{"key":"10.1016\/j.bbadis.2019.165591_bb0945","doi-asserted-by":"crossref","first-page":"467","DOI":"10.3389\/fimmu.2017.00467","article-title":"Uterine natural killer cells: functional distinctions and influence on pregnancy in humans and mice","volume":"8","author":"Gaynor","year":"2017","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.bbadis.2019.165591_bb0950","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1111\/j.1600-0897.2008.00593.x","article-title":"NK cell tolerance and the maternal-fetal interface","volume":"59","author":"Riley","year":"2008","journal-title":"Am. J. Reprod. Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0955","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.placenta.2015.12.001","article-title":"Role of decidual CD14(+) macrophages in the homeostasis of maternal-fetal interface and the differentiation capacity of the cells during pregnancy and parturition","volume":"38","author":"Wang","year":"2016","journal-title":"Placenta"},{"key":"10.1016\/j.bbadis.2019.165591_bb0960","doi-asserted-by":"crossref","first-page":"606","DOI":"10.3389\/fimmu.2014.00606","article-title":"M1\/M2 macrophage polarity in normal and complicated pregnancy","volume":"5","author":"Brown","year":"2014","journal-title":"Front. Immunol."},{"issue":"1","key":"10.1016\/j.bbadis.2019.165591_bb0965","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0191040","article-title":"VEGF may contribute to macrophage recruitment and M2 polarization in the decidua","volume":"13","author":"Wheeler","year":"2018","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0970","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1111\/aji.12288","article-title":"Trophoblast induces monocyte differentiation into CD14+\/CD16+ macrophages","volume":"72","author":"Aldo","year":"2014","journal-title":"Am. J. Reprod. Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0975","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1159\/000333310","article-title":"The immunoprotective role of interleukin-10 in abnormal pregnancy outcome induced by Toxoplasma gondii infection","volume":"73","author":"Zhang","year":"2012","journal-title":"Gynecol. Obstet. Investig."},{"issue":"2","key":"10.1016\/j.bbadis.2019.165591_bb0980","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0056455","article-title":"IL-10 reduces levels of apoptosis in Toxoplasma gondii-infected trophoblasts","volume":"8","author":"Zhao","year":"2013","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0985","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.it.2015.02.002","article-title":"Dynamic control of type I IFN signalling by an integrated network of negative regulators","volume":"36","author":"Porritt","year":"2015","journal-title":"Trends Immunol."},{"key":"10.1016\/j.bbadis.2019.165591_bb0990","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1038\/s41541-018-0074-4","article-title":"A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection","volume":"3","author":"Nelson","year":"2018","journal-title":"NPJ Vaccines"},{"issue":"3","key":"10.1016\/j.bbadis.2019.165591_bb0995","doi-asserted-by":"crossref","first-page":"1","DOI":"10.15585\/mmwr.rr6703a1","article-title":"Prevention and control of seasonal influenza with vaccines: recommendations of the advisory committee on immunization practices\u2014United States, 2018\u201319 influenza season","volume":"67","author":"Grohskopf","year":"2018","journal-title":"MMWR Recomm. Rep."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544391930314X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544391930314X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T21:34:56Z","timestamp":1777584896000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092544391930314X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":199,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2020,3]]}},"alternative-id":["S092544391930314X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2019.165591","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2020,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Epidemiology and pathogenesis of maternal-fetal transmission of Trypanosoma cruzi and a case for vaccine development against congenital Chagas disease","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2019.165591","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"165591"}}