{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,16]],"date-time":"2026-02-16T17:58:25Z","timestamp":1771264705297,"version":"3.50.1"},"reference-count":22,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1016\/j.bbadis.2020.165985","type":"journal-article","created":{"date-parts":[[2020,10,3]],"date-time":"2020-10-03T10:59:06Z","timestamp":1601722746000},"page":"165985","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis"],"prefix":"10.1016","volume":"1867","author":[{"given":"J.","family":"Politei","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Frabasil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Durand","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Di Pietrantonio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Fernandez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Albert\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Velasquez Rivas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Barriales-Villa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Larra\u00f1aga-Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.B.","family":"Schenone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bbadis.2020.165985_bb0005","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.ymgme.2018.02.014","article-title":"Fabry disease revisited: management and treatment recommendations for adult patients","volume":"123","author":"Ortiz","year":"2018","journal-title":"Mol. Genet. Metab."},{"issue":"1\u20132","key":"10.1016\/j.bbadis.2020.165985_bb0010","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.ymgme.2016.10.006","article-title":"Plasma lyso-Gb3: a useful biomarker for the diagnosis and treatment of Fabry disease heterozygotes","volume":"120","author":"Nowak","year":"2017","journal-title":"Mol. Genet. Metab."},{"issue":"2","key":"10.1016\/j.bbadis.2020.165985_bb0015","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1080\/10408447509164014","article-title":"Drug-induced phospholipidoses. II. Tissue distribution of the amphiphilic drug chlorphentermine","volume":"4","author":"L\u00fcllmann","year":"1975","journal-title":"CRC Crit. Rev. Toxicol."},{"issue":"1","key":"10.1016\/j.bbadis.2020.165985_bb0020","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1515\/hsz-2019-0270","article-title":"Emerging mechanisms of drug-induced phospholipidosis","volume":"401","author":"Breiden","year":"2019","journal-title":"Biol. Chem."},{"issue":"3","key":"10.1016\/j.bbadis.2020.165985_bb0025","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1007\/BF00227722","article-title":"Lysosomal glycosphingolipid storage in chloroquine-induced alpha-galactosidase-deficient human endothelial cells with transformation by simian virus 40: in vitro model of Fabry disease","volume":"85","author":"Inagaki","year":"1993","journal-title":"Acta Neuropathol."},{"issue":"1\u20132","key":"10.1016\/j.bbadis.2020.165985_bb0030","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0009-8981(01)00478-8","article-title":"Fabry disease: enzymatic diagnosis in dried blood spots on filter paper","volume":"308","author":"Chamoles","year":"2001","journal-title":"Clin. Chim. Acta"},{"issue":"3","key":"10.1016\/j.bbadis.2020.165985_bb0035","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1053\/hupa.2003.36","article-title":"Chloroquine-induced phospholipidosis of the kidney mimicking Fabry\u2019s disease: case report and review of the literature","volume":"34","author":"M\u00fcller-H\u00f6cker","year":"2003","journal-title":"Hum. Pathol."},{"issue":"3","key":"10.1016\/j.bbadis.2020.165985_bb0040","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1016\/j.kint.2018.02.003","article-title":"Hydroxychloroquine-induced mimic of renal Fabry disease","volume":"94","author":"Sperati","year":"2018","journal-title":"Kidney Int."},{"issue":"5","key":"10.1016\/j.bbadis.2020.165985_bb0045","doi-asserted-by":"crossref","first-page":"533","DOI":"10.1093\/ckj\/sft089","article-title":"Curvilinear bodies in hydroxychloroquine-induced renal phospholipidosis resembling Fabry disease","volume":"6","author":"Costa","year":"2013","journal-title":"Clin. Kidney J."},{"issue":"5","key":"10.1016\/j.bbadis.2020.165985_bb0050","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1038\/modpathol.3800344","article-title":"Chloroquine-induced lipidosis mimicking Fabry disease","volume":"18","author":"Albay","year":"2005","journal-title":"Mod. Pathol."},{"key":"10.1016\/j.bbadis.2020.165985_bb0055","doi-asserted-by":"crossref","first-page":"5315137","DOI":"10.1155\/2018\/5315137","article-title":"In vivo confocal microscopic observations of vortex keratopathy in patients with amiodarone-induced keratopathy and Fabry disease","volume":"2018","author":"Ikegawa","year":"2018","journal-title":"J. Ophthalmol."},{"issue":"2","key":"10.1016\/j.bbadis.2020.165985_bb0060","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1007\/s10545-010-9261-9","article-title":"Toward a consensus in the laboratory diagnostics of Fabry disease - recommendations of a European expert group","volume":"34","author":"Gal","year":"2011","journal-title":"J. Inherit. Metab. Dis."},{"issue":"1","key":"10.1016\/j.bbadis.2020.165985_bb0065","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1161\/CIRCGENETICS.113.000249","article-title":"Gene mutations versus clinically relevant phenotypes: lyso-Gb3 defines Fabry disease","volume":"7","author":"Niemann","year":"2014","journal-title":"Circ. Cardiovasc. Genet."},{"issue":"8","key":"10.1016\/j.bbadis.2020.165985_bb0070","doi-asserted-by":"crossref","first-page":"2812","DOI":"10.1073\/pnas.0712309105","article-title":"Elevated globotriaosylsphingosine is a hallmark of Fabry disease","volume":"105","author":"Aerts","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.bbadis.2020.165985_bb0075","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ymgme.2020.04.006","article-title":"A comprehensive testing algorithm for the diagnosis of Fabry disease in males and females","volume":"130","author":"Stiles","year":"2020","journal-title":"Mol. Genet. Metab."},{"issue":"12","key":"10.1016\/j.bbadis.2020.165985_bb0080","doi-asserted-by":"crossref","first-page":"1863","DOI":"10.1515\/cclm-2018-1301","article-title":"Plasma and dried blood spot lysosphingolipids for the diagnosis of different sphingolipidoses: a comparative study","volume":"57","author":"Polo","year":"2019","journal-title":"Clin. Chem. Lab. Med."},{"issue":"6","key":"10.1016\/j.bbadis.2020.165985_bb0085","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1002\/1873-3468.12104","article-title":"Lysosomal glycosphingolipid catabolism by acid ceramidase: formation of glycosphingoid bases during deficiency of glycosidases","volume":"590","author":"Ferraz","year":"2016","journal-title":"FEBS Lett."},{"issue":"3","key":"10.1016\/j.bbadis.2020.165985_bb0090","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/j.taap.2014.06.014","article-title":"Di-22:6-bis(monoacylglycerol)phosphate: a clinical biomarker of drug-induced phospholipidosis for drug development and safety assessment","volume":"279","author":"Liu","year":"2014","journal-title":"Toxicol. Appl. Pharmacol."},{"issue":"9","key":"10.1016\/j.bbadis.2020.165985_bb0095","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1177\/153537020122600903","article-title":"Drug-induced phospholipidosis: are there functional consequences?","volume":"226","author":"Reasor","year":"2001","journal-title":"Exp. Biol."},{"issue":"1","key":"10.1016\/j.bbadis.2020.165985_bb0100","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1007\/s10565-014-9269-2","article-title":"Maintenance of luminal pH and protease activity in lysosomes\/late endosomes by vacuolar ATPase in chlorpromazine-treated RAW264 cells accumulating phospholipids","volume":"30","author":"Hamaguchi","year":"2014","journal-title":"Cell Biol. Toxicol."},{"issue":"2","key":"10.1016\/j.bbadis.2020.165985_bb0105","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/0014-4827(81)90011-2","article-title":"Inactivation by chloroquine of alpha-galactosidase in cultured human skin fibroblasts","volume":"136","author":"De Groot","year":"1981","journal-title":"Exp. Cell Res."},{"key":"10.1016\/j.bbadis.2020.165985_bb0110","first-page":"A26","article-title":"Fabry keratopathy: molecular pathology of the chloroquineinduced phenocopy","volume":"26","author":"Desnick","year":"1974","journal-title":"Am. J. Hum. Genet."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443920303331?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443920303331?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T05:00:01Z","timestamp":1760418001000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443920303331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":22,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["S0925443920303331"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2020.165985","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2020.165985","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"165985"}}