{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,13]],"date-time":"2026-02-13T09:55:06Z","timestamp":1770976506965,"version":"3.50.1"},"reference-count":10,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100006162","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Ci\u00eancia e Tecnologia do Estado de Pernambuco","doi-asserted-by":"publisher","award":["IBPG-0174-2.02\/14"],"award-info":[{"award-number":["IBPG-0174-2.02\/14"]}],"id":[{"id":"10.13039\/501100006162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008132","name":"Universidade Federal de Pernambuco","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008132","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["GM131919"],"award-info":[{"award-number":["GM131919"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","award":["AMD-0132-2.00\/17"],"award-info":[{"award-number":["AMD-0132-2.00\/17"]}],"id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.bbadis.2020.166053","type":"journal-article","created":{"date-parts":[[2020,12,29]],"date-time":"2020-12-29T12:11:50Z","timestamp":1609243910000},"page":"166053","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Incomplete mitophagy in the mevalonate kinase-deficient Saccharomyces cerevisiae and its relation to the MKD-related autoinflammatory disease in humans"],"prefix":"10.1016","volume":"1867","author":[{"given":"Manuella Maria Silva","family":"Santos","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dami\u00e1n","family":"Gatica","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaqueline","family":"de Az\u00eavedo Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sergio","family":"Crovella","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Klionsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcos Antonio","family":"De Morais Jr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2020.166053_bb0005","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.clim.2012.09.011","article-title":"Mevalonate kinase deficiency, a metabolic autoautoinflammatory disease","volume":"147","author":"van der Burgh","year":"2013","journal-title":"Clin. Immunol."},{"key":"10.1016\/j.bbadis.2020.166053_bb0010","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1007\/s00294-018-0803-2","article-title":"Respiratory deficiency in yeast mevalonate kinase deficient may explain MKD-associate metabolic disorder in humans","volume":"64","author":"Santos","year":"2018","journal-title":"Curr. Genet."},{"key":"10.1016\/j.bbadis.2020.166053_bb0015","doi-asserted-by":"crossref","unstructured":"Y. Zhang, H. Qi, R. Taylor, W. Xu, L.F. Liu, S. Jin, The role of autophagy in mitochondria maintenance: characterization of mitochondrial functions in autophagy-deficient S. cerevisiae strains. Autophagy 3 (2007) 337\u2013346. doi: https:\/\/doi.org\/10.4161\/auto.4127.","DOI":"10.4161\/auto.4127"},{"key":"10.1016\/j.bbadis.2020.166053_bb0020","doi-asserted-by":"crossref","first-page":"32386","DOI":"10.1074\/jbc.M802403200","article-title":"Mitophagy in yeast occurs through a selective mechanism","volume":"283","author":"Kanki","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2020.166053_bb0025","doi-asserted-by":"crossref","first-page":"2288","DOI":"10.1080\/15548627.2015.1107692","article-title":"Atg41\/Icy2 regulates autophagosome formation","volume":"11","author":"Yao","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2020.166053_bb0030","first-page":"35","article-title":"Mechanisms and physiological roles of mitophagy in yeast","volume":"41","author":"Fukuda","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbadis.2020.166053_bb0035","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1038\/sj.cdd.4401697","article-title":"Impairing the bioenergetic status and the biogenesis of mitochondria triggers mitophagy in yeast","volume":"12","author":"Priault","year":"2005","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbadis.2020.166053_bb0040","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1159\/000471235","article-title":"Lack of prenylated proteins, autophagy impairment and apoptosis in SHSY5Y neuronal cell model of mevalonate kinase deficiency","volume":"41","author":"Tricarico","year":"2017","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bbadis.2020.166053_bb0050","article-title":"The mevalonate pathway as a metabolic requirement for autophagy-implications for growth control, proteostasis, and disease","volume":"3","author":"Miettinen","year":"2016","journal-title":"Mol. Cell Oncol."},{"key":"10.1016\/j.bbadis.2020.166053_bb0055","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/s00439-011-1057-y","article-title":"Mitochondrial DNA and inflammatory diseases","volume":"131","author":"Escames","year":"2012","journal-title":"Hum. Genet."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443920304014?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443920304014?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T05:00:50Z","timestamp":1760418050000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443920304014"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["S0925443920304014"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2020.166053","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Incomplete mitophagy in the mevalonate kinase-deficient Saccharomyces cerevisiae and its relation to the MKD-related autoinflammatory disease in humans","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2020.166053","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"166053"}}