{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,29]],"date-time":"2026-07-29T14:00:47Z","timestamp":1785333647681,"version":"3.55.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,7,1]],"date-time":"2022-07-01T00:00:00Z","timestamp":1656633600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK054927"],"award-info":[{"award-number":["DK054927"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["DK120491"],"award-info":[{"award-number":["DK120491"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.bbadis.2021.166146","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T02:53:38Z","timestamp":1618455218000},"page":"166146","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Contribution of podocyte inflammatory exosome release to glomerular inflammation and sclerosis during hyperhomocysteinemia"],"prefix":"10.1016","volume":"1867","author":[{"given":"Dandan","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangbi","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qinghua","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owais M.","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Zou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph K.","family":"Ritter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pin-Lan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2021.166146_bb0005","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1146\/annurev.immunol.021908.132715","article-title":"The inflammasomes: guardians of the body","volume":"27","author":"Martinon","year":"2009","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2021.166146_bb0010","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1146\/annurev-cellbio-101512-122326","article-title":"Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles","volume":"30","author":"Colombo","year":"2014","journal-title":"Annu. Rev. Cell Dev. Biol."},{"issue":"4","key":"10.1016\/j.bbadis.2021.166146_bb0015","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1172\/JCI81132","article-title":"Extracellular vesicles and infectious diseases: new complexity to an old story","volume":"126","author":"Schorey","year":"2016","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2021.166146_bb0020","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.arr.2016.05.001","article-title":"Impact of lysosome status on extracellular vesicle content and release","volume":"32","author":"Eitan","year":"2016","journal-title":"Ageing Res. Rev."},{"issue":"11","key":"10.1016\/j.bbadis.2021.166146_bb0025","doi-asserted-by":"crossref","first-page":"1138","DOI":"10.1038\/ki.2011.292","article-title":"Exosomes and the kidney: prospects for diagnosis and therapy of renal diseases","volume":"80","author":"van Balkom","year":"2011","journal-title":"Kidney Int."},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0030","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1681\/ASN.2015010074","article-title":"Extracellular vesicles in renal diseases: more than novel biomarkers?","volume":"27","author":"Erdbrugger","year":"2016","journal-title":"J. Am. Soc. Nephrol."},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0035","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1681\/ASN.2004070564","article-title":"Apical cell membranes are shed into urine from injured podocytes: a novel phenomenon of podocyte injury","volume":"16","author":"Hara","year":"2005","journal-title":"Journal of the American Society of Nephrology\u202f: JASN"},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0040","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00467-011-2035-2","article-title":"Urinary exosomal WT1 in childhood nephrotic syndrome","volume":"27","author":"Lee","year":"2012","journal-title":"Pediatr. Nephrol."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0045","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s00125-016-4190-2","article-title":"Assessment of urinary microparticles in normotensive patients with type 1 diabetes","volume":"60","author":"Lytvyn","year":"2017","journal-title":"Diabetologia"},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0050","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1007\/s00467-017-3816-z","article-title":"Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases","volume":"34","author":"Stahl","year":"2019","journal-title":"Pediatr. Nephrol."},{"issue":"8","key":"10.1016\/j.bbadis.2021.166146_bb0055","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/s00467-002-0865-7","article-title":"Surface markers of platelet function in idiopathic nephrotic syndrome in children","volume":"17","author":"Tkaczyk","year":"2002","journal-title":"Pediatr. Nephrol."},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0060","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1002\/j.1460-2075.1990.tb08268.x","article-title":"A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence","volume":"9","author":"Rubartelli","year":"1990","journal-title":"EMBO J."},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0065","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/nrcardio.2017.7","article-title":"Extracellular vesicles in coronary artery disease","volume":"14","author":"Boulanger","year":"2017","journal-title":"Nat. Rev. Cardiol."},{"issue":"14","key":"10.1016\/j.bbadis.2021.166146_bb0070","doi-asserted-by":"crossref","first-page":"2697","DOI":"10.1007\/s00018-015-1906-2","article-title":"Extracellular vesicles and atherosclerotic disease","volume":"72","author":"Chistiakov","year":"2015","journal-title":"Cellular and molecular life sciences\u202f: CMLS"},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0075","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s00018-017-2595-9","article-title":"Current knowledge on exosome biogenesis and release","volume":"75","author":"Hessvik","year":"2018","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbadis.2021.166146_bb0080","doi-asserted-by":"crossref","first-page":"403","DOI":"10.3389\/fimmu.2014.00403","article-title":"Exosomes and autophagy: coordinated mechanisms for the maintenance of cellular fitness","volume":"5","author":"Baixauli","year":"2014","journal-title":"Front. Immunol."},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0085","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1111\/j.1600-0854.2007.00677.x","article-title":"Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells","volume":"9","author":"Fader","year":"2008","journal-title":"Traffic"},{"issue":"6","key":"10.1016\/j.bbadis.2021.166146_bb0090","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1080\/15548627.2015.1040976","article-title":"ATG12-ATG3 connects basal autophagy and late endosome function","volume":"11","author":"Murrow","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2021.166146_bb0095","doi-asserted-by":"crossref","first-page":"2712","DOI":"10.1038\/ncomms3712","article-title":"Ongoing activation of sphingosine 1-phosphate receptors mediates maturation of exosomal multivesicular endosomes","volume":"4","author":"Kajimoto","year":"2013","journal-title":"Nat. Commun."},{"issue":"5867","key":"10.1016\/j.bbadis.2021.166146_bb0100","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1126\/science.1153124","article-title":"Ceramide triggers budding of exosome vesicles into multivesicular endosomes","volume":"319","author":"Trajkovic","year":"2008","journal-title":"Science"},{"issue":"14","key":"10.1016\/j.bbadis.2021.166146_bb0105","doi-asserted-by":"crossref","first-page":"10977","DOI":"10.1074\/jbc.M111.324616","article-title":"Sphingolipid-modulated exosome secretion promotes clearance of amyloid-beta by microglia","volume":"287","author":"Yuyama","year":"2012","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0110","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.nbd.2011.01.029","article-title":"Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission","volume":"42","author":"Alvarez-Erviti","year":"2011","journal-title":"Neurobiol. Dis."},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0115","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1002\/1873-3468.12024","article-title":"Exosomes derived from mineralizing osteoblasts promote ST2 cell osteogenic differentiation by alteration of microRNA expression","volume":"590","author":"Cui","year":"2016","journal-title":"FEBS Lett."},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0120","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1006\/geno.1998.5334","article-title":"Cloning and characterization of the full-length cDNA and genomic sequences encoding murine acid ceramidase","volume":"50","author":"Li","year":"1998","journal-title":"Genomics"},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0125","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1166\/msr.2013.1022","article-title":"Cyclic ADP-ribose and NAADP in vascular regulation and diseases","volume":"2","author":"Li","year":"2013","journal-title":"Messenger"},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0063506","article-title":"Dysregulated autophagy contributes to podocyte damage in Fabry\u2019s disease","volume":"8","author":"Liebau","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2021.166146_bb0135","doi-asserted-by":"crossref","first-page":"169","DOI":"10.2147\/DMSO.S61438","article-title":"Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus","volume":"7","author":"Lorber","year":"2014","journal-title":"Diabetes Metab Syndr Obes"},{"issue":"6","key":"10.1016\/j.bbadis.2021.166146_bb0140","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1159\/000110451","article-title":"Mechanism of homocysteine-induced Rac1\/NADPH oxidase activation in mesangial cells: role of guanine nucleotide exchange factor Vav2","volume":"20","author":"Yi","year":"2007","journal-title":"Cell. Physiol. Biochem."},{"key":"10.1016\/j.bbadis.2021.166146_bb0145","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1111\/j.1582-4934.2009.00743.x","article-title":"Formation of lipid raft redox signalling platforms in glomerular endothelial cells: an early event of homocysteine-induced glomerular injury","volume":"13, (9B","author":"Yi","year":"2009","journal-title":"J. Cell. Mol. Med."},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0150","doi-asserted-by":"crossref","first-page":"1977","DOI":"10.1111\/j.1523-1755.2004.00968.x","article-title":"Homocysteine activates NADH\/NADPH oxidase through ceramide-stimulated Rac GTPase activity in rat mesangial cells","volume":"66","author":"Yi","year":"2004","journal-title":"Kidney Int."},{"issue":"7","key":"10.1016\/j.bbadis.2021.166146_bb0155","doi-asserted-by":"crossref","first-page":"5821","DOI":"10.1074\/jbc.M310979200","article-title":"Deoxycholic acid activates the c-Jun N-terminal kinase pathway via FAS receptor activation in primary hepatocytes. Role of acidic sphingomyelinase-mediated ceramide generation in FAS receptor activation","volume":"279","author":"Gupta","year":"2004","journal-title":"J. Biol. Chem."},{"issue":"6","key":"10.1016\/j.bbadis.2021.166146_bb0160","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.1194\/jlr.M072587","article-title":"NLRP3 inflammasome as a novel target for docosahexaenoic acid metabolites to abrogate glomerular injury","volume":"58","author":"Li","year":"2017","journal-title":"J. Lipid Res."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0165","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/ng0795-288","article-title":"Acid sphingomyelinase deficient mice: a model of types a and B Niemann-pick disease","volume":"10","author":"Horinouchi","year":"1995","journal-title":"Nat. Genet."},{"issue":"6","key":"10.1016\/j.bbadis.2021.166146_bb0170","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1016\/j.ajpath.2020.02.008","article-title":"Podocytopathy and Nephrotic syndrome in mice with podocyte-specific deletion of the Asah1 gene: role of ceramide accumulation in glomeruli","volume":"190","author":"Li","year":"2020","journal-title":"Am. J. Pathol."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0175","doi-asserted-by":"crossref","first-page":"C481","DOI":"10.1152\/ajpcell.00150.2019","article-title":"Control of lysosomal TRPML1 channel activity and exosome release by acid ceramidase in mouse podocytes","volume":"317","author":"Li","year":"2019","journal-title":"American journal of physiology. Cell physiology"},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0180","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1159\/000373989","article-title":"Enhanced epithelial-to-mesenchymal transition associated with lysosome dysfunction in podocytes: role of p62\/Sequestosome 1 as a signaling hub","volume":"35","author":"Li","year":"2015","journal-title":"Cellular physiology and biochemistry\u202f: international journal of experimental cellular physiology, biochemistry, and pharmacology"},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0185","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1203\/00006450-200209000-00007","article-title":"The number of podocyte slit diaphragms is decreased in minimal change nephrotic syndrome","volume":"52","author":"Patrakka","year":"2002","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bbadis.2021.166146_bb0190","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.freeradbiomed.2013.10.009","article-title":"Contribution of endogenously produced reactive oxygen species to the activation of podocyte NLRP3 inflammasomes in hyperhomocysteinemia","volume":"67","author":"Abais","year":"2014","journal-title":"Free Radic. Biol. Med."},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0195","doi-asserted-by":"crossref","first-page":"2871","DOI":"10.1074\/jbc.M608083200","article-title":"ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages","volume":"282","author":"Cruz","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"8","key":"10.1016\/j.bbadis.2021.166146_bb0200","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1038\/ni.1636","article-title":"The NALP3 inflammasome is involved in the innate immune response to amyloid-beta","volume":"9","author":"Halle","year":"2008","journal-title":"Nat. Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0205","doi-asserted-by":"crossref","first-page":"1262","DOI":"10.1128\/IAI.01032-08","article-title":"Anthrax lethal toxin triggers the formation of a membrane-associated inflammasome complex in murine macrophages","volume":"77","author":"Nour","year":"2009","journal-title":"Infect. Immun."},{"issue":"12","key":"10.1016\/j.bbadis.2021.166146_bb0210","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1038\/nri2873","article-title":"Sterile inflammation: sensing and reacting to damage","volume":"10","author":"Chen","year":"2010","journal-title":"Nat Rev Immunol"},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0215","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/nri2936","article-title":"Emerging inflammasome effector mechanisms","volume":"11","author":"Lamkanfi","year":"2011","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0220","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1016\/S1097-2765(02)00599-3","article-title":"The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta","volume":"10","author":"Martinon","year":"2002","journal-title":"Mol. Cell"},{"issue":"24","key":"10.1016\/j.bbadis.2021.166146_bb0225","doi-asserted-by":"crossref","first-page":"21119","DOI":"10.1074\/jbc.C200179200","article-title":"The PYRIN-CARD protein ASC is an activating adaptor for caspase-1","volume":"277","author":"Srinivasula","year":"2002","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0230","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1161\/HYPERTENSIONAHA.111.189688","article-title":"Activation of nod-like receptor protein 3 inflammasomes turns on podocyte injury and glomerular sclerosis in hyperhomocysteinemia","volume":"60","author":"Zhang","year":"2012","journal-title":"Hypertension"},{"issue":"13","key":"10.1016\/j.bbadis.2021.166146_bb0235","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1089\/ars.2012.4666","article-title":"NADPH oxidase-mediated triggering of inflammasome activation in mouse podocytes and glomeruli during hyperhomocysteinemia","volume":"18","author":"Abais","year":"2013","journal-title":"Antioxid. Redox Signal."},{"issue":"39","key":"10.1016\/j.bbadis.2021.166146_bb0240","doi-asserted-by":"crossref","first-page":"27159","DOI":"10.1074\/jbc.M114.567537","article-title":"Nod-like receptor protein 3 (NLRP3) inflammasome activation and podocyte injury via thioredoxin-interacting protein (TXNIP) during hyperhomocysteinemia","volume":"289","author":"Abais","year":"2014","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2021.166146_bb0245","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1016\/j.freeradbiomed.2017.02.027","article-title":"Contribution of guanine nucleotide exchange factor Vav2 to NLRP3 inflammasome activation in mouse podocytes during hyperhomocysteinemia","volume":"106","author":"Conley","year":"2017","journal-title":"Free Radic. Biol. Med."},{"issue":"9","key":"10.1016\/j.bbadis.2021.166146_bb0250","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.2174\/1389450117666160817103435","article-title":"Inflammasome activation in chronic glomerular diseases","volume":"18","author":"Conley","year":"2017","journal-title":"Curr. Drug Targets"},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0255","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1016\/j.bbamcr.2019.02.007","article-title":"Lysosomal regulation of extracellular vesicle excretion during d-ribose-induced NLRP3 inflammasome activation in podocytes","volume":"1866","author":"Hong","year":"2019","journal-title":"Biochimica et biophysica acta. Molecular cell research"},{"issue":"6","key":"10.1016\/j.bbadis.2021.166146_bb0260","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1089\/ars.2009.2461","article-title":"Activation of membrane NADPH oxidase associated with lysosome-targeted acid sphingomyelinase in coronary endothelial cells","volume":"12","author":"Bao","year":"2010","journal-title":"Antioxid. Redox Signal."},{"issue":"3","key":"10.1016\/j.bbadis.2021.166146_bb0265","doi-asserted-by":"crossref","first-page":"H992","DOI":"10.1152\/ajpheart.00958.2009","article-title":"Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries","volume":"298","author":"Bao","year":"2010","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"issue":"12","key":"10.1016\/j.bbadis.2021.166146_bb0270","doi-asserted-by":"crossref","first-page":"1294","DOI":"10.1016\/j.bbalip.2010.09.001","article-title":"Visfatin-induced lipid raft redox signaling platforms and dysfunction in glomerular endothelial cells","volume":"1801","author":"Boini","year":"2010","journal-title":"Biochim. Biophys. Acta"},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0275","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1016\/j.ajpath.2011.07.019","article-title":"Acid sphingomyelinase gene deficiency ameliorates the hyperhomocysteinemia-induced glomerular injury in mice","volume":"179","author":"Boini","year":"2011","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0280","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/imr.12908","article-title":"Therapeutic modulation of inflammasome pathways","volume":"297","author":"Chauhan","year":"2020","journal-title":"Immunol. Rev."},{"issue":"2","key":"10.1016\/j.bbadis.2021.166146_bb0285","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1038\/s41401-019-0298-5","article-title":"Endophilin A2 regulates calcium-activated chloride channel activity via selective autophagy-mediated TMEM16A degradation","volume":"41","author":"Liu","year":"2020","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.bbadis.2021.166146_bb0290","doi-asserted-by":"crossref","first-page":"5581","DOI":"10.1038\/s41598-020-62621-8","article-title":"Differential regulation of microRNA-15a by radiation affects angiogenesis and tumor growth via modulation of acid sphingomyelinase","volume":"10","author":"Rana","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2021.166146_bb0295","doi-asserted-by":"crossref","first-page":"2188","DOI":"10.3389\/fimmu.2018.02188","article-title":"From Inflammasome to exosome-does extracellular vesicle secretion constitute an Inflammasome-dependent immune response?","volume":"9","author":"Cypryk","year":"2018","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.bbadis.2021.166146_bb0300","doi-asserted-by":"crossref","first-page":"3085","DOI":"10.4049\/jimmunol.1002051","article-title":"Recognition of cytoplasmic RNA results in cathepsin-dependent inflammasome activation and apoptosis in human macrophages","volume":"186","author":"Rintahaka","year":"2011","journal-title":"J. Immunol."},{"issue":"8","key":"10.1016\/j.bbadis.2021.166146_bb0305","doi-asserted-by":"crossref","first-page":"5052","DOI":"10.4049\/jimmunol.0802968","article-title":"P2X7 receptor-stimulated secretion of MHC class II-containing exosomes requires the ASC\/NLRP3 inflammasome but is independent of caspase-1","volume":"182","author":"Qu","year":"2009","journal-title":"J. Immunol."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544392100079X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S092544392100079X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T05:03:33Z","timestamp":1760418213000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S092544392100079X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":61,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S092544392100079X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2021.166146","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Contribution of podocyte inflammatory exosome release to glomerular inflammation and sclerosis during hyperhomocysteinemia","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2021.166146","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"166146"}}