{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,16]],"date-time":"2026-05-16T01:45:20Z","timestamp":1778895920631,"version":"3.51.4"},"reference-count":87,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,3,1]],"date-time":"2023-03-01T00:00:00Z","timestamp":1677628800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"Narodowe Centrum Nauki","doi-asserted-by":"publisher","award":["2016\/23\/D\/NZ3\/01631"],"award-info":[{"award-number":["2016\/23\/D\/NZ3\/01631"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","award":["POWER.03.02.00-00-1028\/17-00"],"award-info":[{"award-number":["POWER.03.02.00-00-1028\/17-00"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2023,3]]},"DOI":"10.1016\/j.bbadis.2022.166633","type":"journal-article","created":{"date-parts":[[2022,12,22]],"date-time":"2022-12-22T02:20:40Z","timestamp":1671675640000},"page":"166633","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Mitochondrial dynamics, elimination and biogenesis during post-ischemic recovery in ischemia-resistant and ischemia-vulnerable gerbil hippocampal regions"],"prefix":"10.1016","volume":"1869","author":[{"given":"Maria","family":"Kawalec","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Piotr","family":"Wojtyniak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ewelina","family":"Bielska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Lewczuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Boraty\u0144ska-Jasi\u0144ska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Ber\u0119sewicz-Haller","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ma\u0142gorzata","family":"Frontczak-Baniewicz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magdalena","family":"Gewartowska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Zab\u0142ocka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2022.166633_bb0005","doi-asserted-by":"crossref","DOI":"10.1002\/ccr3.5246","article-title":"Anticoagulated de novo atrial flutter complicated by transitory ischemic attack in fatal COVID-19","volume":"10","author":"Finsterer","year":"2022","journal-title":"Clin. Case Rep."},{"key":"10.1016\/j.bbadis.2022.166633_bb0010","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1161\/STROKEAHA.121.035270","article-title":"Stroke among patients hospitalized with COVID-19: results from the American Heart Association COVID-19 cardiovascular disease registry","volume":"53","author":"Shakil","year":"2022","journal-title":"Stroke"},{"key":"10.1016\/j.bbadis.2022.166633_bb0015","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1161\/STROKEAHA.108.192218","volume":"40","author":"Easton","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.bbadis.2022.166633_bb0020","article-title":"The development of novel drug treatments for stroke patients: a review","volume":"23","author":"Frank","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0025","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1152\/physrev.00005.2018","article-title":"Evolving and expanding the roles of mitophagy as a homeostatic and pathogenic process","volume":"99","author":"Gustafsson","year":"2019","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbadis.2022.166633_bb0030","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1242\/jcs.114.5.867","article-title":"Control of mitochondrial morphology by a human mitofusin","volume":"114","author":"Santel","year":"2001","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0035","doi-asserted-by":"crossref","first-page":"15927","DOI":"10.1073\/pnas.0407043101","article-title":"OPA1 requires mitofusin 1 to promote mitochondrial fusion","volume":"101","author":"Cipolat","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbadis.2022.166633_bb0040","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1016\/j.bbamcr.2013.02.002","article-title":"New insights into the function and regulation of mitochondrial fission","volume":"1833","author":"Otera","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbadis.2022.166633_bb0045","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.1038\/sj.emboj.7601253","article-title":"Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons","volume":"25","author":"Barsoum","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2022.166633_bb0050","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1038\/s41419-020-2461-9","article-title":"Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways","volume":"11","author":"Duan","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbadis.2022.166633_bb0055","doi-asserted-by":"crossref","first-page":"3119","DOI":"10.1523\/JNEUROSCI.1926-19.2020","article-title":"Deletion of a neuronal Drp1 activator protects against cerebral ischemia","volume":"40","author":"Flippo","year":"2020","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0060","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1016\/j.mcn.2016.08.010","article-title":"Mitochondrial dynamics following global cerebral ischemia","volume":"76","author":"Kumar","year":"2016","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0063206","article-title":"Mitochondrial dynamics associated with oxygen-glucose deprivation in rat primary neuronal cultures","volume":"8","author":"Wappler","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2022.166633_bb0070","doi-asserted-by":"crossref","first-page":"4453","DOI":"10.3390\/ijms15034453","article-title":"Exercise pretreatment promotes mitochondrial dynamic protein OPA1 expression after cerebral ischemia in rats","volume":"15","author":"Zhang","year":"2014","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0075","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.redox.2018.03.002","article-title":"Diverse roles of mitochondria in ischemic stroke","volume":"16","author":"Yang","year":"2018","journal-title":"Redox Biol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0080","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1038\/cdd.2012.18","article-title":"Inhibition of Drp1 provides neuroprotection in vitro and in vivo","volume":"19","author":"Grohm","year":"2012","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbadis.2022.166633_bb0085","doi-asserted-by":"crossref","first-page":"1027","DOI":"10.1080\/01616412.2016.1215050","article-title":"Effect of inhibiting mitochondrial fission on energy metabolism in rat hippocampal neurons during ischemia\/reperfusion injury","volume":"38","author":"Li","year":"2016","journal-title":"Neurol. Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0090","doi-asserted-by":"crossref","first-page":"528","DOI":"10.1111\/cns.12266","article-title":"Amelioration of ischemic mitochondrial injury and bax-dependent outer membrane permeabilization by Mdivi-1","volume":"20","author":"Zhao","year":"2014","journal-title":"CNS Neurosci. Ther."},{"key":"10.1016\/j.bbadis.2022.166633_bb0095","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.biocel.2015.09.011","article-title":"Mitofusin 2 ameliorates hypoxia-induced apoptosis via mitochondrial function and signaling pathways","volume":"69","author":"Peng","year":"2015","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0100","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1038\/79944","article-title":"OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28","volume":"26","author":"Alexander","year":"2000","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0105","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/79936","article-title":"Nuclear gene OPA1, encoding a mitochondrial dynamin-related protein, is mutated in dominant optic atrophy","volume":"26","author":"Delettre","year":"2000","journal-title":"Nat.Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0110","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1177\/0883073818778203","article-title":"De novo DNM1L variant in a teenager with progressive paroxysmal dystonia and lethal super-refractory myoclonic status epilepticus","volume":"33","author":"Ryan","year":"2018","journal-title":"J. Child Neurol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0115","doi-asserted-by":"crossref","first-page":"1788","DOI":"10.1093\/hmg\/ddab360","article-title":"A partial reduction of Drp1 improves cognitive behavior and enhances mitophagy, autophagy and dendritic spines in a transgenic tau mouse model of Alzheimer disease","volume":"31","author":"Kandimalla","year":"2022","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0120","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1126\/science.1219855","article-title":"Mitochondrial fission, fusion, and stress","volume":"337","author":"Youle","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbadis.2022.166633_bb0125","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.neuroscience.2012.05.035","article-title":"Remodeling of synapses in the CA1 area of the hippocampus after transient global ischemia","volume":"218","author":"Ruan","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2022.166633_bb0130","doi-asserted-by":"crossref","DOI":"10.3390\/cells11071193","article-title":"Induction of mitochondrial fragmentation and mitophagy after neonatal hypoxia-ischemia","volume":"11","author":"Nair","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2022.166633_bb0135","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1007\/s12264-015-1544-6","article-title":"Regulation of mitophagy in ischemic brain injury","volume":"31","author":"Yuan","year":"2015","journal-title":"Neurosci.Bull."},{"key":"10.1016\/j.bbadis.2022.166633_bb0140","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.neuroscience.2020.02.035","article-title":"Activation of PGC-1\u03b1 and mitochondrial biogenesis protects against prenatal hypoxic-ischemic brain injury","volume":"432","author":"Jia","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2022.166633_bb0145","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1089\/rej.2020.2315","article-title":"Activation of CB1R-dependent PGC-1\u03b1 is involved in the improved mitochondrial biogenesis induced by electroacupuncture pretreatment","volume":"24","author":"Sun","year":"2021","journal-title":"Rejuvenation Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0150","doi-asserted-by":"crossref","DOI":"10.1177\/17590914211012888","article-title":"Neuronal pentraxin 1 promotes hypoxic-ischemic neuronal injury by impairing mitochondrial biogenesis via interactions with active Bax[6A7] and mitochondrial hexokinase II","volume":"13","author":"Al Rahim","year":"2021","journal-title":"ASN Neuro"},{"key":"10.1016\/j.bbadis.2022.166633_bb0155","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1096\/fj.05-3786fje","article-title":"A strong neuroprotective effect of the autonomous C-terminal peptide of IGF-1 Ec (MGF) in brain ischemia","volume":"19","author":"Dluzniewska","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.bbadis.2022.166633_bb0160","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1007\/BF00691853","article-title":"Selective vulnerability in the gerbil hippocampus following transient ischemia","volume":"62","author":"Kirino","year":"1984","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0165","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1007\/s11064-017-2263-3","article-title":"Ischemia\/Reperfusion-induced translocation of PKC\u03b2II to mitochondria as an important mediator of a protective signaling mechanism in an ischemia-resistant region of the hippocampus","volume":"42","author":"Krupska","year":"2017","journal-title":"Neurochem. Res."},{"issue":"4","key":"10.1016\/j.bbadis.2022.166633_bb0170","doi-asserted-by":"crossref","first-page":"1621","DOI":"10.1007\/s12035-020-02208-6","article-title":"Hippocampal sector-specific metabolic profiles reflect endogenous strategy for ischemia-reperfusion insult resistance","volume":"58","author":"Krupska","year":"2020","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0175","doi-asserted-by":"crossref","first-page":"13843","DOI":"10.1074\/jbc.M808515200","article-title":"Loss of PINK1 function promotes mitophagy through effects on oxidative stress and mitochondrial fission","volume":"284","author":"Dagda","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2022.166633_bb0180","doi-asserted-by":"crossref","DOI":"10.3390\/cells10092177","article-title":"A universal approach to analyzing transmission electron microscopy with ImageJ","volume":"10","author":"Lam","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2022.166633_bb0185","doi-asserted-by":"crossref","first-page":"795","DOI":"10.1083\/jcb.200809125","article-title":"Parkin is recruited selectively to impaired mitochondria and promotes their autophagy","volume":"183","author":"Narendra","year":"2008","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0190","doi-asserted-by":"crossref","first-page":"680","DOI":"10.1038\/227680a0","article-title":"Cleavage of structural proteins during the assembly of the head of bacteriophage T4","volume":"227","author":"Laemmli","year":"1970","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2022.166633_bb0195","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ab.2015.11.022","article-title":"Total protein or high-abundance protein: which offers the best loading control for Western blotting?","volume":"496","author":"Thacker","year":"2016","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbadis.2022.166633_bb0200","doi-asserted-by":"crossref","DOI":"10.1002\/pmic.201600189","article-title":"Tubulin or not tubulin: heading toward Total protein staining as loading control in Western blots","volume":"17","author":"Moritz","year":"2017","journal-title":"Proteomics"},{"key":"10.1016\/j.bbadis.2022.166633_bb0205","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gks596","article-title":"Primer3\u2013new capabilities and interfaces","volume":"40","author":"Untergasser","year":"2012","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0210","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.bbadis.2022.166633_bb0215","first-page":"209","article-title":"Asymatric demage of the CA1 sector of ammon's horn after short-term forebrain ischemia in Mongolian gerbils","volume":"30","author":"Gadamski","year":"1992","journal-title":"Neropatol. Polska"},{"key":"10.1016\/j.bbadis.2022.166633_bb0220","doi-asserted-by":"crossref","first-page":"840","DOI":"10.1002\/(SICI)1097-4547(19990915)57:6<840::AID-JNR9>3.0.CO;2-Z","article-title":"AP1 transcriptional factor activation and its relation to apoptosis of hippocampal CA1 pyramidal neurons after transient ischemia in gerbils","volume":"57","author":"Domanska-Janik","year":"1999","journal-title":"J. Neurosci.Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0225","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0006-8993(82)90833-2","article-title":"Delayed neuronal death in the gerbil hippocampus following ischemia","volume":"239","author":"Kirino","year":"1982","journal-title":"Brain Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0230","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1093\/gerona\/63.4.350","article-title":"Age-induced morphological, biochemical, and functional alterations in isolated mitochondria from murine skeletal muscle","volume":"63","author":"Figueiredo","year":"2008","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0235","doi-asserted-by":"crossref","first-page":"7115","DOI":"10.1074\/jbc.M116.762567","article-title":"The short variant of the mitochondrial dynamin OPA1 maintains mitochondrial energetics and cristae structure","volume":"292","author":"Lee","year":"2017","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2022.166633_bb0240","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1242\/jcs.159186","article-title":"OPA1 processing in cell death and disease - the long and short of it","volume":"129","author":"MacVicar","year":"2016","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0245","doi-asserted-by":"crossref","first-page":"882","DOI":"10.1097\/00004647-199808000-00008","article-title":"Bcl-x(l) bax interaction after transient global ischemia","volume":"18","author":"Antonawich","year":"1998","journal-title":"J.Cereb.Blood Flow Metab."},{"key":"10.1016\/j.bbadis.2022.166633_bb0250","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22168504","article-title":"Mitochondrial metabolism behind region-specific resistance to ischemia-reperfusion injury in gerbil hippocampus. Role of PKC\u03b2II and phosphate-activated glutaminase","volume":"22","author":"Ber\u0119sewicz-Haller","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0255","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.expneurol.2008.08.018","article-title":"Diazepam delays the death of hippocampal CA1 neurons following global ischemia","volume":"214","author":"Corbett","year":"2008","journal-title":"Exp.Neurol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0260","doi-asserted-by":"crossref","first-page":"1057","DOI":"10.1002\/ar.21390","article-title":"Comparative ultrastructural analysis of mitochondria in the CA1 and CA3 hippocampal pyramidal cells following global ischemia in mongolian gerbils","volume":"294","author":"Radenovic","year":"2011","journal-title":"Anat. Rec. (Hoboken)"},{"key":"10.1016\/j.bbadis.2022.166633_bb0265","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1002\/hipo.20555","article-title":"A molecular blueprint of gene expression in hippocampal subregions CA1, CA3, and DG is conserved in the brain of the common marmoset","volume":"19","author":"Datson","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbadis.2022.166633_bb0270","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1016\/j.celrep.2019.08.093","article-title":"Hippocampal subregions express distinct dendritic transcriptomes that reveal differences in mitochondrial function in CA2","volume":"29","author":"Farris","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbadis.2022.166633_bb0275","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1111\/j.1471-4159.2011.07550.x","article-title":"Why are hippocampal CA1 neurons vulnerable but motor cortex neurons resistant to transient ischemia?","volume":"120","author":"Zhu","year":"2012","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2022.166633_bb0280","doi-asserted-by":"crossref","first-page":"865","DOI":"10.3233\/JAD-160812","article-title":"Gender-specific degeneration of dementia-related subcortical structures throughout the lifespan","volume":"55","author":"Nemeth","year":"2017","journal-title":"J. Alzheimer's Dis."},{"key":"10.1016\/j.bbadis.2022.166633_bb0285","doi-asserted-by":"crossref","first-page":"2691","DOI":"10.2147\/NDT.S130710","article-title":"Transient global amnesia: current perspectives","volume":"13","author":"Spiegel","year":"2017","journal-title":"Neuropsychiatr. Dis. Treat."},{"key":"10.1016\/j.bbadis.2022.166633_bb0290","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1017\/S0317167100003929","article-title":"Pathology of mitochondrial encephalomyopathies","volume":"32","author":"Sarnat","year":"2005","journal-title":"Can. J. Neurol. Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0295","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1007\/s00018-010-0435-2","article-title":"Mitochondrial dynamics in cell death and neurodegeneration","volume":"67","author":"Cho","year":"2010","journal-title":"Cell Mol.Life Sci."},{"key":"10.1016\/j.bbadis.2022.166633_bb0300","doi-asserted-by":"crossref","first-page":"3919","DOI":"10.1093\/hmg\/ddq306","article-title":"Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease","volume":"19","author":"Kim","year":"2010","journal-title":"Hum.Mol.Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0305","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1007\/s10863-014-9575-7","article-title":"Mitochondrial dynamics: cell-type and hippocampal region specific changes following global cerebral ischemia","volume":"47","author":"Owens","year":"2015","journal-title":"J. Bioenerg.Biomembr."},{"key":"10.1016\/j.bbadis.2022.166633_bb0310","doi-asserted-by":"crossref","first-page":"1332","DOI":"10.1093\/hmg\/ddy042","article-title":"Hippocampal mutant APP and amyloid beta-induced cognitive decline, dendritic spine loss, defective autophagy, mitophagy and mitochondrial abnormalities in a mouse model of Alzheimer's disease","volume":"27","author":"Manczak","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2020.165975","article-title":"Donepezil provides neuroprotective effects against brain injury and Alzheimer's pathology under conditions of cardiac ischemia\/reperfusion injury","volume":"1867","author":"Ongnok","year":"2021","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.bbadis.2022.166633_bb0320","doi-asserted-by":"crossref","first-page":"1120","DOI":"10.1002\/jnr.24781","article-title":"Mitochondrial dysfunction, mitophagy, and role of dynamin-related protein 1 in Alzheimer's disease","volume":"99","author":"Medala","year":"2021","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0325","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.4161\/auto.25132","article-title":"Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance","volume":"9","author":"Zhang","year":"2013","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2022.166633_bb0330","first-page":"629","article-title":"The role of autophagy in the pathogenesis of ischemic stroke","volume":"19","author":"Shi","year":"2021","journal-title":"Curr. Neuropharmacol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0335","doi-asserted-by":"crossref","first-page":"3146","DOI":"10.1111\/bph.12655","article-title":"Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy","volume":"171","author":"Jiang","year":"2014","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0340","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1038\/cdd.2016.140","article-title":"Global ischemia induces lysosomal-mediated degradation of mTOR and activation of autophagy in hippocampal neurons destined to die","volume":"24","author":"Hwang","year":"2017","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbadis.2022.166633_bb0345","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1002\/acn3.507","article-title":"Rapamycin prevents cerebral stroke by modulating apoptosis and autophagy in penumbra in rats","volume":"5","author":"Wu","year":"2018","journal-title":"Ann. Clin. Transl. Neurol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0350","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2020.1797280","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy","volume":"17","author":"Klionsky","year":"2021","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2022.166633_bb0355","doi-asserted-by":"crossref","first-page":"56","DOI":"10.5483\/BMBRep.2020.53.1.283","article-title":"The central regulator p62 between ubiquitin proteasome system and autophagy and its role in the mitophagy and Parkinson's disease","volume":"53","author":"Shin","year":"2020","journal-title":"BMB Rep."},{"key":"10.1016\/j.bbadis.2022.166633_bb0360","doi-asserted-by":"crossref","first-page":"11696","DOI":"10.1073\/pnas.1500624112","article-title":"Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration","volume":"112","author":"Stevens","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbadis.2022.166633_bb0365","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000298","article-title":"PINK1 is selectively stabilized on impaired mitochondria to activate Parkin","volume":"8","author":"Narendra","year":"2010","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0370","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.bbrc.2015.03.045","article-title":"Roles of PTEN-induced putative kinase 1 and dynamin-related protein 1 in transient global ischemia-induced hippocampal neuronal injury","volume":"460","author":"Chen","year":"2015","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2022.166633_bb0375","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.3748\/wjg.v26.i15.1758","article-title":"PTEN-induced kinase 1-induced dynamin-related protein 1 Ser637 phosphorylation reduces mitochondrial fission and protects against intestinal ischemia reperfusion injury","volume":"26","author":"Qasim","year":"2020","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0380","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S1673-8527(08)60099-5","article-title":"Number matters: control of mammalian mitochondrial DNA copy number","volume":"36","author":"Clay Montier","year":"2009","journal-title":"J. Genet. Genomics"},{"key":"10.1016\/j.bbadis.2022.166633_bb0385","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/0006-291X(92)90517-O","article-title":"Counting target molecules by exponential polymerase chain reaction: copy number of mitochondrial DNA in rat tissues","volume":"183","author":"Wiesner","year":"1992","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2022.166633_bb0390","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1001\/jamacardio.2017.3683","article-title":"Association of Mitochondrial DNA copy number with cardiovascular disease","volume":"2","author":"Ashar","year":"2017","journal-title":"JAMA Cardiol."},{"key":"10.1016\/j.bbadis.2022.166633_bb0395","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1007\/s12265-019-09943-9","article-title":"mtDNA copy number contributes to all-cause mortality of lacunar infarct in a chinese prospective stroke population","volume":"13","author":"Song","year":"2020","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"10.1016\/j.bbadis.2022.166633_bb0400","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1042\/BST0351228","article-title":"Mitochondrial dysfunction in neurodegenerative disorders","volume":"35","author":"Baron","year":"2007","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbadis.2022.166633_bb0405","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/ng1769","article-title":"High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease","volume":"38","author":"Bender","year":"2006","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2022.166633_bb0410","doi-asserted-by":"crossref","DOI":"10.3390\/genes12081246","article-title":"Interactions of mitochondrial transcription factor A with DNA damage: mechanistic insights and functional implications","volume":"12","author":"Chew","year":"2021","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.bbadis.2022.166633_bb0415","doi-asserted-by":"crossref","first-page":"3057","DOI":"10.1161\/STROKEAHA.108.520114","article-title":"Rapidly increased neuronal mitochondrial biogenesis after hypoxic-ischemic brain injury","volume":"39","author":"Yin","year":"2008","journal-title":"Stroke"},{"key":"10.1016\/j.bbadis.2022.166633_bb0420","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.cell.2006.09.024","article-title":"Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators","volume":"127","author":"St-Pierre","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.bbadis.2022.166633_bb0425","doi-asserted-by":"crossref","first-page":"3149","DOI":"10.1161\/STROKEAHA.108.543769","article-title":"Mitochondrial targets for stroke: focusing basic science research toward development of clinically translatable therapeutics","volume":"40","author":"Vosler","year":"2009","journal-title":"Stroke"},{"key":"10.1016\/j.bbadis.2022.166633_bb0430","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/j.apsb.2021.11.003","article-title":"Mitochondrial complex I as a therapeutic target for Alzheimer's disease","volume":"12","author":"Trushina","year":"2022","journal-title":"Acta Pharm. Sin. B"},{"key":"10.1016\/j.bbadis.2022.166633_bb0435","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.neuropharm.2014.07.002","article-title":"Mitochondria autophagy is induced after hypoxic\/ischemic stress in a Drp1 dependent manner: the role of inhibition of Drp1 in ischemic brain damage","volume":"86","author":"Zuo","year":"2014","journal-title":"Neuropharmacology"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443922003040?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443922003040?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T05:11:21Z","timestamp":1760418681000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443922003040"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,3]]},"references-count":87,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2023,3]]}},"alternative-id":["S0925443922003040"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2022.166633","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2023,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mitochondrial dynamics, elimination and biogenesis during post-ischemic recovery in ischemia-resistant and ischemia-vulnerable gerbil hippocampal regions","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2022.166633","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"166633"}}