{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T23:13:44Z","timestamp":1790810024412,"version":"4.1.0"},"reference-count":60,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS111378"],"award-info":[{"award-number":["NS111378"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS117148"],"award-info":[{"award-number":["NS117148"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["NS116383"],"award-info":[{"award-number":["NS116383"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.bbadis.2023.166937","type":"journal-article","created":{"date-parts":[[2023,11,3]],"date-time":"2023-11-03T22:45:55Z","timestamp":1699051555000},"page":"166937","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"title":["Humanin ameliorates TBI-related cognitive impairment by attenuating mitochondrial dysfunction and inflammation"],"prefix":"10.1016","volume":"1870","author":[{"given":"Pavan","family":"Thapak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhe","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Victoria","family":"Palafox-Sanchez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanglin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Gomez-Pinilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2023.166937_bb0005","doi-asserted-by":"crossref","first-page":"77","DOI":"10.2147\/DDDT.S154391","article-title":"Sinomenine reduces neuronal cell apoptosis in mice after traumatic brain injury via its effect on mitochondrial pathway","volume":"12","author":"Fu","year":"2018","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.bbadis.2023.166937_bb0010","doi-asserted-by":"crossref","first-page":"1080","DOI":"10.3171\/2017.10.JNS17352","article-title":"Estimating the global incidence of traumatic brain injury","volume":"130","author":"Dewan","year":"2019","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.bbadis.2023.166937_bb0015","doi-asserted-by":"crossref","first-page":"2129","DOI":"10.1089\/neu.2018.6291","article-title":"A role for postsynaptic density 95 and its binding partners in models of traumatic brain injury","volume":"36","author":"Patel","year":"2019","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bbadis.2023.166937_bb0020","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1016\/j.bbadis.2015.01.018","article-title":"Flavonoid derivative 7,8-DHF attenuates TBI pathology via TrkB activation","volume":"1852","author":"Agrawal","year":"2015","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2023.166937_bb0025","doi-asserted-by":"crossref","first-page":"2864","DOI":"10.1091\/mbc.e09-02-0168","article-title":"Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor \u03b1\/WSX-1\/gp130","volume":"20","author":"Hashimoto","year":"2009","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbadis.2023.166937_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2020.118679","article-title":"Humanin: a mitochondrial-derived peptide in the treatment of apoptosis-related diseases","volume":"264","author":"Hazafa","year":"2021","journal-title":"Life Sci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0035","doi-asserted-by":"crossref","DOI":"10.3389\/fnagi.2019.00123","article-title":"Humanin, a mitochondrial-derived peptide released by astrocytes, prevents synapse loss in hippocampal neurons","volume":"11","author":"Z\u00e1rate","year":"2019","journal-title":"Front. Aging Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0040","doi-asserted-by":"crossref","first-page":"3894","DOI":"10.1038\/s41467-018-06222-0","article-title":"Single cell molecular alterations reveal target cells and pathways of concussive brain injury","volume":"9","author":"Arneson","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2023.166937_bb0045","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1523\/JNEUROSCI.2469-20.2020","article-title":"Traumatic brain injury causes chronic cortical inflammation and neuronal dysfunction mediated by microglia","volume":"41","author":"Witcher","year":"2021","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0050","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2019.00528","article-title":"Traumatic brain injuries: pathophysiology and potential therapeutic targets","volume":"13","author":"Ng","year":"2019","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0055","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1038\/s41593-020-00783-4","article-title":"Reactive astrocyte nomenclature, definitions, and future directions","volume":"24","author":"Escartin","year":"2021","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0060","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1186\/s12974-019-1561-x","article-title":"Dasatinib regulates LPS-induced microglial and astrocytic neuroinflammatory responses by inhibiting AKT\/STAT3 signaling","volume":"16","author":"Ryu","year":"2019","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.bbadis.2023.166937_bb0065","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1111\/j.1471-4159.2011.07610.x","article-title":"STAT3 signaling after traumatic brain injury","volume":"120","author":"Oliva","year":"2012","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2023.166937_bb0070","doi-asserted-by":"crossref","first-page":"13042","DOI":"10.1073\/pnas.2135111100","article-title":"Interaction between the Alzheimer\u2019s survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis","volume":"100","author":"Ikonen","year":"2003","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0075","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1167\/iovs.15-17053","article-title":"The mitochondrial-derived peptide humanin protects RPE cells from oxidative stress, senescence, and mitochondrial dysfunction","volume":"57","author":"Sreekumar","year":"2016","journal-title":"Investig. Opthalmol. Vis. Sci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0080","doi-asserted-by":"crossref","first-page":"1250","DOI":"10.1038\/ncomms2238","article-title":"Involvement of PGC-1\u03b1 in the formation and maintenance of neuronal dendritic spines","volume":"3","author":"Cheng","year":"2012","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2023.166937_bb0085","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/cells11010111","article-title":"Covering the role of PGC-1\u03b1 in the nervous system","volume":"11","author":"Kuczynska","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2023.166937_bb0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagen.2022.130097","article-title":"Roles of humanin and derivatives on the pathology of neurodegenerative diseases and cognition","volume":"1866","author":"Thiankhaw","year":"2022","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.bbadis.2023.166937_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbagen.2021.130024","article-title":"Humanin and Alzheimer\u2019s disease: the beginning of a new field","volume":"1866","author":"Niikura","year":"2022","journal-title":"Biochim. Biophys. Acta Gen. Subj."},{"key":"10.1016\/j.bbadis.2023.166937_bb0100","doi-asserted-by":"crossref","first-page":"11185","DOI":"10.18632\/aging.103534","article-title":"The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan","volume":"12","author":"Yen","year":"2020","journal-title":"Aging"},{"key":"10.1016\/j.bbadis.2023.166937_bb0105","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/j.bbadis.2017.03.007","article-title":"7,8-Dihydroxyflavone facilitates the action exercise to restore plasticity and functionality: implications for early brain trauma recovery","volume":"1863","author":"Krishna","year":"2017","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2023.166937_bb0110","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/srep00431","article-title":"High-fat diet transition reduces brain DHA levels associated with altered brain plasticity and behaviour","volume":"2","author":"Sharma","year":"2012","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2023.166937_bb0115","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1037\/h0077579","article-title":"Memory deficits associated with senescence: a neurophysiological and behavioral study in the rat","volume":"93","author":"Barnes","year":"1979","journal-title":"J. Comp. Physiol. Psychol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0120","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/s12017-021-08675-x","article-title":"Tranilast, a Transient Receptor Potential Vanilloid 2 Channel (TRPV2) inhibitor attenuates amyloid \u03b2-induced cognitive impairment: possible mechanisms","volume":"24","author":"Thapak","year":"2022","journal-title":"NeuroMolecular Med."},{"key":"10.1016\/j.bbadis.2023.166937_bb0125","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1007\/s10571-020-01012-z","article-title":"Neuroprotective effect of 2-Aminoethoxydiphenyl Borate (2-APB) in amyloid \u03b2-induced memory dysfunction: a mechanistic study","volume":"42","author":"Thapak","year":"2022","journal-title":"Cell. Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2021.166078","article-title":"The interaction between brain and liver regulates lipid metabolism in the TBI pathology","volume":"1867","author":"Palafox-S\u00e1nchez","year":"2021","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2023.166937_bb0135","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2019104073","article-title":"A novel approach to measure mitochondrial respiration in frozen biological samples","volume":"39","author":"Acin-Perez","year":"2020","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2023.166937_bb0140","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/j.bbadis.2013.12.004","article-title":"Coupling energy homeostasis with a mechanism to support plasticity in brain trauma","volume":"1842","author":"Agrawal","year":"2014","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2023.166937_bb0145","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.cjtee.2020.10.001","article-title":"Glucose metabolism: a link between traumatic brain injury and Alzheimer\u2019s disease","volume":"24","author":"Xu","year":"2021","journal-title":"Chin. J. Traumatol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0150","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1111\/j.1476-5381.2012.02025.x","article-title":"Mitochondria in traumatic brain injury and mitochondrial-targeted multipotential therapeutic strategies","volume":"167","author":"Cheng","year":"2012","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0155","doi-asserted-by":"crossref","first-page":"2995","DOI":"10.1111\/jcmm.14206","article-title":"Role of mitochondrial calcium uniporter-mediated Ca2+ and iron accumulation in traumatic brain injury","volume":"23","author":"Zhang","year":"2019","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.bbadis.2023.166937_bb0160","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/s12974-016-0613-8","article-title":"Oncostatin M promotes excitotoxicity by inhibiting glutamate uptake in astrocytes: implications in HIV-associated neurotoxicity","volume":"13","author":"Moidunny","year":"2016","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.bbadis.2023.166937_bb0165","first-page":"H643","article-title":"Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR","volume":"277","author":"Russell","year":"1999","journal-title":"Am. J. Phys. Heart Circ. Phys."},{"key":"10.1016\/j.bbadis.2023.166937_bb0170","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.gendis.2015.12.002","article-title":"Mitochondrial dysfunction activates the AMPK signaling and autophagy to promote cell survival","volume":"3","author":"Zhao","year":"2016","journal-title":"Genes Dis."},{"key":"10.1016\/j.bbadis.2023.166937_bb0175","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.cell.2006.09.024","article-title":"Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators","volume":"127","author":"St-Pierre","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.bbadis.2023.166937_bb0180","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12964","article-title":"20-HETE synthesis inhibition attenuates traumatic brain injury\u2013induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1\/PGC-1\u03b1 pathway: a translational study","volume":"54","author":"Cui","year":"2021","journal-title":"Cell Prolif."},{"key":"10.1016\/j.bbadis.2023.166937_bb0185","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.freeradbiomed.2018.12.014","article-title":"Melatonin receptor activation provides cerebral protection after traumatic brain injury by mitigating oxidative stress and inflammation via the Nrf2 signaling pathway","volume":"131","author":"Wang","year":"2019","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2023.166937_bb0190","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neuroscience.2020.03.036","article-title":"A role for PGC-1\u03b1 in transcription and excitability of neocortical and hippocampal excitatory neurons","volume":"435","author":"McMeekin","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2023.166937_bb0195","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1089\/scd.2015.0076","article-title":"Differentiation of human neural stem cells into motor neurons stimulates mitochondrial biogenesis and decreases glycolytic flux","volume":"24","author":"O\u2019Brien","year":"2015","journal-title":"Stem Cells Dev."},{"key":"10.1016\/j.bbadis.2023.166937_bb0200","doi-asserted-by":"crossref","DOI":"10.3389\/fnmol.2017.00443","article-title":"SIRT1\/PGC-1\u03b1 signaling promotes mitochondrial functional recovery and reduces apoptosis after intracerebral hemorrhage in rats","volume":"10","author":"Zhou","year":"2018","journal-title":"Front. Mol. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0205","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1097\/MOL.0b013e328328d0a4","article-title":"PGC-1\u03b1, SIRT1 and AMPK, an energy sensing network that controls energy expenditure","volume":"20","author":"Cant\u00f3","year":"2009","journal-title":"Curr. Opin. Lipidol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0210","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.freeradbiomed.2008.04.038","article-title":"Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury","volume":"45","author":"Ansari","year":"2008","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2023.166937_bb0215","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1007\/s12031-015-0500-2","article-title":"AMPK plays a dual role in regulation of CREB\/BDNF pathway in mouse primary hippocampal cells","volume":"56","author":"Huang","year":"2015","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0220","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1089\/neu.2010.1372","article-title":"The hormone ghrelin prevents traumatic brain injury induced intestinal dysfunction","volume":"27","author":"Bansal","year":"2010","journal-title":"J. Neurotrauma"},{"key":"10.1016\/j.bbadis.2023.166937_bb0225","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2019.01120","article-title":"Elevated serum levels of inflammation-related cytokines in mild traumatic brain injury are associated with cognitive performance","volume":"10","author":"Sun","year":"2019","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0230","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1590\/0004-282X20150083","article-title":"Memory deficit associated with increased brain proinflammatory cytokine levels and neurodegeneration in acute ischemic stroke","volume":"73","author":"Silva","year":"2015","journal-title":"Arq. Neuropsiquiatr."},{"key":"10.1016\/j.bbadis.2023.166937_bb0235","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1038\/s41423-019-0213-5","article-title":"Dissemination of brain inflammation in traumatic brain injury","volume":"16","author":"Shi","year":"2019","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0240","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1111\/bph.13125","article-title":"The contribution of astrocytes and microglia to traumatic brain injury","volume":"173","author":"Karve","year":"2016","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0245","doi-asserted-by":"crossref","first-page":"977","DOI":"10.3171\/2017.5.JNS163165","article-title":"Upregulation of miR-216a exerts neuroprotective effects against ischemic injury through negatively regulating JAK2\/STAT3-involved apoptosis and inflammatory pathways","volume":"130","author":"Tian","year":"2019","journal-title":"J. Neurosurg."},{"key":"10.1016\/j.bbadis.2023.166937_bb0250","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.4049\/jimmunol.172.4.2225","article-title":"WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27","volume":"172","author":"Pflanz","year":"2004","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0255","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.714943","article-title":"Janus kinase inhibition ameliorates ischemic stroke injury and neuroinflammation through reducing NLRP3 inflammasome activation via JAK2\/STAT3 pathway inhibition","volume":"12","author":"Zhu","year":"2021","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2023.166937_bb0260","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1002\/glia.10186","article-title":"Upregulation of gp130 and STAT3 activation in the rat hippocampus following transient forebrain ischemia","volume":"41","author":"Choi","year":"2003","journal-title":"Glia"},{"key":"10.1016\/j.bbadis.2023.166937_bb0265","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1007\/s12264-014-1479-3","article-title":"Humanin attenuates Alzheimer-like cognitive deficits and pathological changes induced by amyloid \u03b2-peptide in rats","volume":"30","author":"Chai","year":"2014","journal-title":"Neurosci. Bull."},{"key":"10.1016\/j.bbadis.2023.166937_bb0270","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1007\/s11064-012-0951-6","article-title":"Neuroprotective peptide humanin inhibits inflammatory response in astrocytes induced by lipopolysaccharide","volume":"38","author":"Zhao","year":"2013","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbadis.2023.166937_bb0275","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/brain\/awaa321","article-title":"The synapse in traumatic brain injury","volume":"144","author":"Jamjoom","year":"2021","journal-title":"Brain"},{"key":"10.1016\/j.bbadis.2023.166937_bb0280","doi-asserted-by":"crossref","first-page":"3219","DOI":"10.1523\/JNEUROSCI.4486-04.2005","article-title":"Differential regulation of AMPA receptor and GABA receptor trafficking by tumor necrosis factor-\u03b1","volume":"25","author":"Stellwagen","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2023.166937_bb0285","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1038\/nature01627","article-title":"Humanin peptide suppresses apoptosis by interfering with Bax activation","volume":"423","author":"Guo","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2023.166937_bb0290","doi-asserted-by":"crossref","first-page":"E659","DOI":"10.1152\/ajpendo.00249.2020","article-title":"Mitochondrial-derived peptides in energy metabolism","volume":"319","author":"Merry","year":"2020","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbadis.2023.166937_bb0295","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1007\/s13311-016-0477-8","article-title":"Astrocytes: integrative regulators of neuroinflammation in stroke and other neurological diseases","volume":"13","author":"Cekanaviciute","year":"2016","journal-title":"Neurotherapeutics"},{"key":"10.1016\/j.bbadis.2023.166937_bb0300","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/nature21029","article-title":"Neurotoxic reactive astrocytes are induced by activated microglia","volume":"541","author":"Liddelow","year":"2017","journal-title":"Nature"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443923003034?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443923003034?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:09:25Z","timestamp":1778551765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443923003034"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":60,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2]]}},"alternative-id":["S0925443923003034"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2023.166937","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Humanin ameliorates TBI-related cognitive impairment by attenuating mitochondrial dysfunction and inflammation","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2023.166937","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"166937"}}