{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T12:01:27Z","timestamp":1753272087785,"version":"3.41.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["8207141715","82374097"],"award-info":[{"award-number":["8207141715","82374097"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2022A1515011706"],"award-info":[{"award-number":["2022A1515011706"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010618","name":"Guangzhou University of Chinese Medicine","doi-asserted-by":"publisher","award":["2023PY0201"],"award-info":[{"award-number":["2023PY0201"]}],"id":[{"id":"10.13039\/501100010618","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021B1515140003","2022A1515110954"],"award-info":[{"award-number":["2021B1515140003","2022A1515110954"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2024,4]]},"DOI":"10.1016\/j.bbadis.2024.167051","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T09:16:19Z","timestamp":1707297379000},"page":"167051","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy"],"prefix":"10.1016","volume":"1870","author":[{"given":"Xiaohong","family":"Zheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaowei","family":"Lu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuxian","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shiting","family":"Gong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Baoyi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingfeng","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jincan","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ziren","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhonghui","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiannan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yucui","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0005","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/1040841X.2022.2045899","article-title":"The role of microbiome: a novel insight into urolithiasis","volume":"49","author":"Hong","year":"2023","journal-title":"Crit. Rev. Microbiol."},{"issue":"6","key":"10.1016\/j.bbadis.2024.167051_bb0010","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.purol.2020.03.003","article-title":"Composition of urinary calculi: lessons from a French epidemiologic retrospective study","volume":"30","author":"Roger","year":"2020","journal-title":"Prog. Urol."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0015","first-page":"91","article-title":"Evaluation of urinary stone composition and differentiation between urinary stones and phleboliths using single-source dual-energy computed tomography","volume":"71","author":"Ogawa","year":"2017","journal-title":"Acta Med. Okayama"},{"key":"10.1016\/j.bbadis.2024.167051_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.saa.2022.120867","article-title":"Detection of the mineral constituents in human renal calculi by vibrational spectroscopic analysis combined with allied techniques powder XRD, TGA, SEM, IR imaging and TXRF","volume":"270","author":"Deshpande","year":"2022","journal-title":"Spectrochim. Acta A Mol. Biomol. Spectrosc."},{"issue":"11","key":"10.1016\/j.bbadis.2024.167051_bb0025","doi-asserted-by":"crossref","first-page":"2623","DOI":"10.1111\/ajt.12926","article-title":"Recurrent 2,8-dihydroxyadenine nephropathy: a rare but preventable cause of renal allograft failure","volume":"14","author":"Zaidan","year":"2014","journal-title":"Am. J. Transplant."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0030","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1007\/BF00861588","article-title":"Gout, uric acid and purine metabolism in paediatric nephrology","volume":"7","author":"Cameron","year":"1993","journal-title":"Pediatr. Nephrol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0035","first-page":"10","article-title":"A case of 2,8-DHA crystalline nephropathy caused by adenine phosphoribosyltransferase deficiency: diagnosis and treatment","author":"Kunou","year":"2022","journal-title":"CEN Case Rep."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167051_bb0040","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1681\/ASN.2019080827","article-title":"Cellular and molecular mechanisms of kidney injury in 2,8-dihydroxyadenine nephropathy","volume":"31","author":"Klinkhammer","year":"2020","journal-title":"J. Am. Soc. Nephrol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0045","first-page":"45","article-title":"Adenine phosphoribosyltransferase deficiency: an underdiagnosed cause of lithiasis and renal failure","volume":"5","author":"Marra","year":"2012","journal-title":"JIMD Rep."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0050","doi-asserted-by":"crossref","first-page":"462","DOI":"10.4103\/1319-2442.229280","article-title":"Unusual cause of crystalline nephropathy","volume":"29","author":"Gopalakrishnan","year":"2018","journal-title":"Saudi J. Kidney Dis. Transpl."},{"issue":"13","key":"10.1016\/j.bbadis.2024.167051_bb0055","first-page":"215","article-title":"Treatment options for gout","volume":"114","author":"Engel","year":"2017","journal-title":"Dtsch. Arztebl. Int."},{"issue":"12","key":"10.1016\/j.bbadis.2024.167051_bb0060","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1002\/acn3.671","article-title":"Pilot trial of inosine to elevate urate levels in amyotrophic lateral sclerosis","volume":"5","author":"Nicholson","year":"2018","journal-title":"Ann. Clin. Transl. Neurol."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0065","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1073\/pnas.91.2.742","article-title":"Hyperuricemia and urate nephropathy in urate oxidase-deficient mice","volume":"91","author":"Wu","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0070","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.kint.2017.04.031","article-title":"Knockout of the urate oxidase gene provides a stable mouse model of hyperuricemia associated with metabolic disorders","volume":"93","author":"Lu","year":"2018","journal-title":"Kidney Int."},{"issue":"02","key":"10.1016\/j.bbadis.2024.167051_bb0075","first-page":"48","article-title":"A new purine metabolite, 2,8-dihydroxyadenine, might involve urate sediment igniting gout","volume":"11","author":"Zhang","year":"2020","journal-title":"Di 4 Jun Yi Da Xue Bao"},{"issue":"3","key":"10.1016\/j.bbadis.2024.167051_bb0080","doi-asserted-by":"crossref","DOI":"10.1172\/JCI139927","article-title":"Biomarkers of inflammation and repair in kidney disease progression","volume":"131","author":"Puthumana","year":"2021","journal-title":"J. Clin. Invest."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167051_bb0085","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/j.biocel.2008.04.028","article-title":"CCL2 DNA vaccine to treat renal disease","volume":"41","author":"Watson","year":"2009","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"23\u201324","key":"10.1016\/j.bbadis.2024.167051_bb0090","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1016\/j.cca.2011.07.023","article-title":"Urinary monocyte chemoattractant protein-1 in renal disease","volume":"412","author":"Kim","year":"2011","journal-title":"Clin. Chim. Acta"},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0095","doi-asserted-by":"crossref","first-page":"8598","DOI":"10.1038\/s41598-018-26870-y","article-title":"CCL2 deficiency protects against chronic renal injury in murine renovascular hypertension","volume":"8","author":"Kashyap","year":"2018","journal-title":"Sci. Rep."},{"issue":"20","key":"10.1016\/j.bbadis.2024.167051_bb0100","article-title":"Expression and clinical significance of CCL2 in chronic uric acid nephropathy","volume":"23","author":"Deng","year":"2016","journal-title":"Zhongguo Jiceng Yiyao"},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0105","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000314943","article-title":"Evaluation of five interleukin genes for association with end-stage renal disease in white Europeans","volume":"32","author":"Buckham","year":"2010","journal-title":"Am. J. Nephrol."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0110","doi-asserted-by":"crossref","first-page":"34","DOI":"10.4103\/0971-4065.135350","article-title":"Interleukin-1 gene cluster variants in hemodialysis patients with end stage renal disease: an association and meta-analysis","volume":"25","author":"Tripathi","year":"2015","journal-title":"Indian J. Nephrol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2021.798719","article-title":"Identification of inflammation-related biomarker pro-ADM for male patients with gout by comprehensive analysis","volume":"12","author":"Qiu","year":"2022","journal-title":"Front. Immunol."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167051_bb0120","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1016\/j.urology.2009.10.031","article-title":"2,8-dihydroxyadenine nephrolithiasis induces developmental stage-specific alterations in gene expression in mouse kidney","volume":"75","author":"Chen","year":"2010","journal-title":"Urology"},{"key":"10.1016\/j.bbadis.2024.167051_bb0125","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1007\/978-1-4939-3578-9_5","article-title":"The gene expression omnibus database","volume":"1418","author":"Clough","year":"2016","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0130","doi-asserted-by":"crossref","first-page":"D991","DOI":"10.1093\/nar\/gks1193","article-title":"NCBI GEO: archive for functional genomics data sets\u2013update","volume":"41","author":"Barrett","year":"2013","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.bbadis.2024.167051_bb0135","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1016\/j.molp.2020.06.009","article-title":"TBtools: an integrative toolkit developed for interactive analyses of big biological data","volume":"13","author":"Chen","year":"2020","journal-title":"Mol. Plant"},{"issue":"5","key":"10.1016\/j.bbadis.2024.167051_bb0140","doi-asserted-by":"crossref","first-page":"P3","DOI":"10.1186\/gb-2003-4-5-p3","article-title":"DAVID: database for annotation, visualization, and integrated discovery","volume":"4","author":"Dennis","year":"2003","journal-title":"Genome Biol."},{"issue":"D1","key":"10.1016\/j.bbadis.2024.167051_bb0145","doi-asserted-by":"crossref","first-page":"D605","DOI":"10.1093\/nar\/gkaa1074","article-title":"The STRING database in 2021: customizable protein-protein networks, and functional characterization of user-uploaded gene\/measurement sets","volume":"49","author":"Szklarczyk","year":"2021","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbadis.2024.167051_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.111004","article-title":"Renoprotective effects of enzyme-hydrolyzed polysaccharides from Auricularia polytricha on adenine-induced chronic kidney diseases in mice","volume":"135","author":"Song","year":"2021","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.bbadis.2024.167051_bb0155","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1016\/j.ijbiomac.2020.01.095","article-title":"Ameliorate effects of soybean soluble polysaccharide on adenine-induced chronic renal failure in mice","volume":"149","author":"Hou","year":"2020","journal-title":"Int. J. Biol. Macromol."},{"issue":"10","key":"10.1016\/j.bbadis.2024.167051_bb0160","doi-asserted-by":"crossref","first-page":"2609","DOI":"10.1038\/s41401-022-00898-3","article-title":"Dihydroartemisinin suppresses renal fibrosis in mice by inhibiting DNA-methyltransferase 1 and increasing Klotho","volume":"43","author":"Zhou","year":"2022","journal-title":"Acta Pharmacol. Sin."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0165","doi-asserted-by":"crossref","first-page":"P53","DOI":"10.1159\/000090503","article-title":"Expression profiling of crystal-induced injury in human kidney epithelial cells","volume":"103","author":"Liang","year":"2006","journal-title":"Nephron Physiol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.113941","article-title":"Coptisine protects against hyperuricemic nephropathy through alleviating inflammation, oxidative stress and mitochondrial apoptosis via PI3K\/Akt signaling pathway","volume":"156","author":"Liu","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167051_bb0175","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1364\/BOE.485187","article-title":"In vivo longitudinal 920 nm two-photon intravital kidney imaging of a dynamic 2,8-DHA crystal formation and tubular deterioration in the adenine-induced chronic kidney disease mouse model","volume":"14","author":"Choi","year":"2023","journal-title":"Biomed. Opt. Express"},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0180","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/j.kint.2022.02.039","article-title":"Current kidney function parameters overestimate kidney tissue repair in reversible experimental kidney disease","volume":"102","author":"Klinkhammer","year":"2022","journal-title":"Kidney Int."},{"issue":"21","key":"10.1016\/j.bbadis.2024.167051_bb0185","doi-asserted-by":"crossref","first-page":"3271","DOI":"10.2169\/internalmedicine.9332-22","article-title":"Urine xanthine crystals in hematologic malignancies with tumor lysis syndrome","volume":"61","author":"Ito","year":"2022","journal-title":"Intern. Med."},{"key":"10.1016\/j.bbadis.2024.167051_bb0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102459","article-title":"Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease","volume":"56","author":"Wollenhaupt","year":"2022","journal-title":"Redox Biol."},{"issue":"6","key":"10.1016\/j.bbadis.2024.167051_bb0195","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1080\/15548627.2017.1309485","article-title":"Autophagy and kidney inflammation","volume":"13","author":"Kimura","year":"2017","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2024.167051_bb0200","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.redox.2015.09.039","article-title":"The balance of powers: redox regulation of fibrogenic pathways in kidney injury","volume":"6","author":"Okamura","year":"2015","journal-title":"Redox Biol."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167051_bb0205","doi-asserted-by":"crossref","first-page":"F107","DOI":"10.1152\/ajprenal.00037.2022","article-title":"Chemokine CCL2 from proximal tubular epithelial cells contributes to sepsis-induced acute kidney injury","volume":"323","author":"Jia","year":"2022","journal-title":"Am. J. Physiol. Renal Physiol."},{"key":"10.1016\/j.bbadis.2024.167051_bb0210","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/9389432","article-title":"New markers of inflammation and tubular damage in children with chronic kidney disease","volume":"2017","author":"Musia\u0142","year":"2017","journal-title":"Dis. Markers"},{"issue":"7","key":"10.1016\/j.bbadis.2024.167051_bb0215","doi-asserted-by":"crossref","first-page":"R421","DOI":"10.1530\/ERC-17-0309","article-title":"The role of IL-1B in breast cancer bone metastasis","volume":"25","author":"Tulotta","year":"2018","journal-title":"Endocr. Relat. Cancer"},{"key":"10.1016\/j.bbadis.2024.167051_bb0220","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.911968","article-title":"Excess uric acid induces gouty nephropathy through crystal formation: a review of recent insights","volume":"13","author":"Mei","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"1","key":"10.1016\/j.bbadis.2024.167051_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166825","article-title":"2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function","volume":"1870","author":"Moellmann","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"3","key":"10.1016\/j.bbadis.2024.167051_bb0230","doi-asserted-by":"crossref","first-page":"412","DOI":"10.4103\/0253-7613.96351","article-title":"Allopurinol-induced DRESS syndrome","volume":"44","author":"Yaylac\u0131","year":"2012","journal-title":"Indian J. Pharmacol."},{"issue":"3","key":"10.1016\/j.bbadis.2024.167051_bb0235","doi-asserted-by":"crossref","first-page":"e77","DOI":"10.1097\/MJT.0000000000000037","article-title":"Challenges in diagnosis, management, and treatment of allopurinol-induced DRESS syndrome: case report and literature review","volume":"22","author":"Thankachen","year":"2015","journal-title":"Am. J. Ther."},{"issue":"10","key":"10.1016\/j.bbadis.2024.167051_bb0240","doi-asserted-by":"crossref","first-page":"10327","DOI":"10.21037\/apm-21-1564","article-title":"The major cardiovascular events of febuxostat versus allopurinol in treating gout or asymptomatic hyperuricemia: a systematic review and meta-analysis","volume":"10","author":"Wang","year":"2021","journal-title":"Ann. Palliat. Med."},{"issue":"7","key":"10.1016\/j.bbadis.2024.167051_bb0245","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1002\/clc.23643","article-title":"Cardiovascular safety of febuxostat compared to allopurinol for the treatment of gout: a systematic and meta-analysis","volume":"44","author":"Gao","year":"2021","journal-title":"Clin. Cardiol."},{"issue":"13","key":"10.1016\/j.bbadis.2024.167051_bb0250","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1056\/NEJMoa1710895","article-title":"Cardiovascular safety of febuxostat or allopurinol in patients with gout","volume":"378","author":"White","year":"2018","journal-title":"N. Engl. Med."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924000401?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924000401?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T16:56:48Z","timestamp":1751216208000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443924000401"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4]]},"references-count":50,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4]]}},"alternative-id":["S0925443924000401"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167051","relation":{},"ISSN":["0925-4439"],"issn-type":[{"type":"print","value":"0925-4439"}],"subject":[],"published":{"date-parts":[[2024,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Discovery of 2,8-dihydroxyadenine in HUA patients with uroliths and biomarkers for its associated nephropathy","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167051","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167051"}}