{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T05:23:39Z","timestamp":1790659419155,"version":"4.1.0"},"reference-count":79,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.bbadis.2024.167097","type":"journal-article","created":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T07:25:43Z","timestamp":1708759543000},"page":"167097","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"title":["Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome"],"prefix":"10.1016","volume":"1870","author":[{"given":"Cristine Marie Yde","family":"Ohki","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cec\u00edlia","family":"Benazzato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vanessa","family":"van der Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia V.","family":"Fran\u00e7a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen M.","family":"Toledo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael Rahal Guaragna","family":"Machado","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle Bastos","family":"Araujo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle Bruna Leal","family":"Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romulo S.","family":"Neris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iranaia","family":"Assun\u00e7\u00e3o-Miranda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isis Nem","family":"de Oliveira Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara O.","family":"Nogueira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo Emilio Corr\u00eaa","family":"Leite","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e9lio","family":"van der Linden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia P.","family":"Figueiredo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edison Luiz","family":"Durigon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julia R.","family":"Clarke","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabiele Baldino","family":"Russo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia Cristina Baleeiro","family":"Beltr\u00e3o-Braga","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2024.167097_bb0005","doi-asserted-by":"crossref","DOI":"10.2471\/BLT.16.176990","article-title":"Defining the syndrome associated with congenital Zika virus infection","volume":"94","author":"Costello","year":"2016","journal-title":"Bull. World Health Organ."},{"key":"10.1016\/j.bbadis.2024.167097_bb0010","doi-asserted-by":"crossref","first-page":"598","DOI":"10.2105\/AJPH.2016.303115","article-title":"Initial Description of the Presumed Congenital Zika Syndrome","volume":"106","author":"de B. Miranda-Filho","year":"2016","journal-title":"Am. J. Public Health"},{"key":"10.1016\/j.bbadis.2024.167097_bb0015","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1473-3099(16)00095-5","article-title":"Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study","volume":"16","author":"Calvet","year":"2016","journal-title":"Lancet Infect. Dis."},{"issue":"2016","key":"10.1016\/j.bbadis.2024.167097_bb0020","first-page":"159","article-title":"Notes from the field\u202f: evidence of Zika virus infection in brain and placental tissues from two congenitally infected newborns and two fetal losses \u2014 Brazil","volume":"65","author":"Martines","year":"2015","journal-title":"MMWR Morb. Mortal Wkly. Rep."},{"key":"10.1016\/j.bbadis.2024.167097_bb0025","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004517","article-title":"Zika virus infection and stillbirths: a case of hydrops fetalis, hydranencephaly and fetal demise","volume":"10","author":"Sarno","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.bbadis.2024.167097_bb0030","doi-asserted-by":"crossref","first-page":"951","DOI":"10.1056\/NEJMoa1600651","article-title":"Zika virus associated with microcephaly","volume":"374","author":"Mlakar","year":"2016","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbadis.2024.167097_bb0035","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/nature18296","article-title":"The Brazilian Zika virus strain causes birth defects in experimental models","volume":"534","author":"Cugola","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2024.167097_bb0040","series-title":"Transplant Proc","first-page":"3955","article-title":"Swine dental pulp stem cells inhibit T-cell proliferation","author":"Tang","year":"2011"},{"issue":"2002","key":"10.1016\/j.bbadis.2024.167097_bb0045","first-page":"1135","article-title":"Intrauterine West Nile virus infection--New York","volume":"51","author":"Centers for Disease Control and Prevention (CDC)","year":"2002","journal-title":"MMWR Morb. Mortal Wkly. Rep."},{"key":"10.1016\/j.bbadis.2024.167097_bb0050","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1128\/iai.34.1.26-29.1981","article-title":"Congenital infection of mice with Japanese encephalitis virus","volume":"34","author":"Mathur","year":"1981","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbadis.2024.167097_bb0055","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1007\/BF01249709","article-title":"Zika virus infection of the central nervous system of mice","volume":"35","author":"Bell","year":"1971","journal-title":"Arch. Gesamte. Virusforsch."},{"key":"10.1016\/j.bbadis.2024.167097_bb0060","doi-asserted-by":"crossref","first-page":"7117","DOI":"10.1073\/pnas.1719266115","article-title":"Human induced pluripotent stem cell-derived glial cells and neural progenitors display divergent responses to Zika and dengue infections","volume":"115","author":"Muffat","year":"2018","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.bbadis.2024.167097_bb0065","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fncel.2019.00064","article-title":"Zika virus impairs neurogenesis and synaptogenesis pathways in human neural stem cells and neurons","volume":"13","author":"Rosa-Fernandes","year":"2019","journal-title":"Front. Cell. Neurosci."},{"issue":"2018","key":"10.1016\/j.bbadis.2024.167097_bb0070","first-page":"181","article-title":"Glia as architects of central nervous system formation and function","volume":"362","author":"Allen","year":"1979","journal-title":"Science"},{"key":"10.1016\/j.bbadis.2024.167097_bb0075","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.neuron.2017.09.056","article-title":"Cell biology of astrocyte-synapse interactions","volume":"96","author":"Allen","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2024.167097_bb0080","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/s00401-017-1671-4","article-title":"Glioma: experimental models and reality","volume":"133","author":"Lenting","year":"2017","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0085","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00401-009-0619-8","article-title":"Astrocytes: biology and pathology","volume":"119","author":"Sofroniew","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0090","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.neuron.2015.10.037","article-title":"Synaptic integration of adult-born hippocampal neurons is locally controlled by astrocytes","volume":"88","author":"Sultan","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2024.167097_bb0095","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.3727\/096368911X566235","article-title":"Feeder-free derivation of induced pluripotent stem cells from human immature dental pulp stem cells","volume":"20","author":"Beltr\u00e3o-Braga","year":"2011","journal-title":"Cell Transplant."},{"key":"10.1016\/j.bbadis.2024.167097_bb0100","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1016\/j.biopsych.2017.09.021","article-title":"Modeling the interplay between neurons and astrocytes in autism using human induced pluripotent stem cells","volume":"83","author":"Russo","year":"2018","journal-title":"Biol. Psychiatry"},{"issue":"2008","key":"10.1016\/j.bbadis.2024.167097_bb0105","first-page":"1232","article-title":"Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia","volume":"14","author":"Lanciotti","year":"2007","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.bbadis.2024.167097_bb0110","series-title":"The Childhood Autism Rating Scale (CARS)","author":"Schopler","year":"1988"},{"key":"10.1016\/j.bbadis.2024.167097_bb0115","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1101\/gr.107524.110","article-title":"The genome analysis toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data","volume":"20","author":"McKenna","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.bbadis.2024.167097_bb0120","article-title":"Haplotype-based variant detection from short-read sequencing","author":"Garrison","year":"2012","journal-title":"ArXiv: Genomics"},{"key":"10.1016\/j.bbadis.2024.167097_bb0125","doi-asserted-by":"crossref","first-page":"1007S","DOI":"10.1093\/jn\/130.4.1007S","article-title":"Glutamate as a neurotransmitter in the brain: review of physiology and pathology","volume":"130","author":"Meldrum","year":"2000","journal-title":"J. Nutr."},{"key":"10.1016\/j.bbadis.2024.167097_bb0130","series-title":"MMWR. Surveillance Summaries","first-page":"1","article-title":"Prevalence of autism spectrum disorder among children aged 8 years \u2014 autism and developmental disabilities monitoring network, 11 sites, United States, 2014","volume":"67","author":"Baio","year":"2018"},{"key":"10.1016\/j.bbadis.2024.167097_bb0135","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1038\/nature20612","article-title":"Genome-wide changes in lncRNA, splicing, and regional gene expression patterns in autism","volume":"540","author":"Parikshak","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2024.167097_bb0140","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aay6736","article-title":"Molecular alterations in the extracellular matrix in the brains of newborns with congenital Zika syndrome","volume":"13","author":"Aguiar","year":"2020","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bbadis.2024.167097_bb0145","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.meegid.2017.01.015","article-title":"African and Asian Zika virus strains differentially induce early antiviral responses in primary human astrocytes","volume":"49","author":"Hamel","year":"2017","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0150","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1038\/s41421-018-0017-2","article-title":"Zika virus propagation and release in human fetal astrocytes can be suppressed by neutral sphingomyelinase-2 inhibitor GW4869","volume":"4","author":"Huang","year":"2018","journal-title":"Cell Discov."},{"key":"10.1016\/j.bbadis.2024.167097_bb0155","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12868-018-0407-2","article-title":"Characterisation of Zika virus infection in primary human astrocytes","volume":"19","author":"Stefanik","year":"2018","journal-title":"BMC Neurosci."},{"key":"10.1016\/j.bbadis.2024.167097_bb0160","first-page":"1","article-title":"Zika virus induces astrocyte differentiation in neural stem cells","author":"Lossia","year":"2017","journal-title":"J. Neurovirol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0165","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.stemcr.2017.01.008","article-title":"Differential responses of human fetal brain neural stem cells to Zika virus infection","volume":"8","author":"Mcgrath","year":"2017","journal-title":"Stem Cell Rep."},{"key":"10.1016\/j.bbadis.2024.167097_bb0170","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.stem.2011.10.007","article-title":"Postnatal neurogenesis in the human forebrain: from two migratory streams to dribbles","volume":"9","author":"Yang","year":"2011","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.bbadis.2024.167097_bb0175","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fimmu.2017.01016","article-title":"Zika virus promotes neuronal cell death in a non-cell autonomous manner by triggering the release of neurotoxic factors","volume":"8","author":"Olmo","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0180","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/jnc.12263","article-title":"IL-1\u03b2 and TNF-\u03b1 induce neurotoxicity through glutamate production: a potential role for neuronal glutaminase","volume":"125","author":"Ye","year":"2013","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2024.167097_bb0185","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0301-0082(00)00067-8","article-title":"Glutamate uptake","volume":"65","author":"Danbolt","year":"2001","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0190","doi-asserted-by":"crossref","first-page":"2484","DOI":"10.1002\/jcp.22609","article-title":"Role of excitatory amino acid transporter-2 (EAAT2) and glutamate in neurodegeneration: opportunities for developing novel therapeutics","volume":"226","author":"Kim","year":"2011","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0195","doi-asserted-by":"crossref","first-page":"1506","DOI":"10.1016\/j.cellbi.2008.08.020","article-title":"Japanese encephalitis virus differentially modulates the induction of multiple pro-inflammatory mediators in human astrocytoma and astroglioma cell-lines","volume":"32","author":"Mishra","year":"2008","journal-title":"Cell Biol. Int."},{"key":"10.1016\/j.bbadis.2024.167097_bb0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-018-0989-4","article-title":"Zika virus-induced hyper excitation precedes death of mouse primary neuron","volume":"15","author":"Gaburro","year":"2018","journal-title":"Virol. J."},{"key":"10.1016\/j.bbadis.2024.167097_bb0205","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1128\/JVI.00354-15","article-title":"Biology of Zika virus infection in human skin cells","volume":"89","author":"Hamel","year":"2015","journal-title":"J. Virol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0210","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1093\/hmg\/ddx382","article-title":"Modeling neuro-immune interactions during Zika virus infection","volume":"27","author":"Mesci","year":"2018","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbadis.2024.167097_bb0215","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.chom.2012.08.009","article-title":"The TIM and TAM families of phosphatidylserine receptors mediate dengue virus entry","volume":"12","author":"Meertens","year":"2012","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbadis.2024.167097_bb0220","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.celrep.2016.12.045","article-title":"Axl mediates ZIKA virus entry in human glial cells and modulates innate immune responses","volume":"18","author":"Meertens","year":"2017","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbadis.2024.167097_bb0225","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.1016\/j.cell.2007.10.034","article-title":"TAM receptors are pleiotropic inhibitors of the innate immune response","volume":"131","author":"Rothlin","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.bbadis.2024.167097_bb0230","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.jaut.2010.08.001","article-title":"Disrupted Mer receptor tyrosine kinase expression leads to enhanced MZ B-cell responses","volume":"35","author":"Shao","year":"2010","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2024.167097_bb0235","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1084\/jem.20051725","article-title":"Twist mediates suppression of inflammation by type I IFNs and Axl","volume":"203","author":"Sharif","year":"2006","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbadis.2024.167097_bb0240","doi-asserted-by":"crossref","DOI":"10.1128\/jvi.00556-23","article-title":"Zika virus infection induces interleukin-1\u03b2-mediated inflammatory responses by macrophages in the brain of an adult mouse model","volume":"97","author":"Jeong","year":"2023","journal-title":"J. Virol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0245","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.cyto.2018.03.034","article-title":"Cytokine profile in autistic patients","volume":"108","author":"Eftekharian","year":"2018","journal-title":"Cytokine"},{"key":"10.1016\/j.bbadis.2024.167097_bb0250","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1186\/1742-2094-8-52","article-title":"IL-6 is increased in the cerebellum of autistic brain and alters neural cell adhesion, migration and synaptic formation","volume":"8","author":"Wei","year":"2011","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.bbadis.2024.167097_bb0255","series-title":"Diagnostic and Statistical Manual of Mental Disorders","author":"American Psychiatric Association","year":"2013"},{"key":"10.1016\/j.bbadis.2024.167097_bb0260","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.1038\/s41591-019-0496-1","article-title":"Delayed childhood neurodevelopment and neurosensory alterations in the second year of life in a prospective cohort of ZIKV-exposed children","volume":"25","author":"Nielsen-Saines","year":"2019","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbadis.2024.167097_bb0265","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/j.neuron.2008.09.037","article-title":"Removal of FKBP12 enhances mTOR-raptor interactions, LTP, memory, and perseverative\/repetitive behavior","volume":"60","author":"Hoeffer","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2024.167097_bb0270","first-page":"11.22.1","article-title":"Behavioral phenotyping for autism spectrum disorders in mice","volume":"72","author":"Chang","year":"2017","journal-title":"Curr. Protoc. Toxicol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0275","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.adh0043","article-title":"Prenatal Zika virus infection has sex-specific effects on infant physical development and mother-infant social interactions","volume":"15","author":"Moadab","year":"2023","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bbadis.2024.167097_bb0280","doi-asserted-by":"crossref","DOI":"10.1186\/1741-7007-9-54","article-title":"Identification and characterization of a set of conserved and new regulators of cytoskeletal organization, cell morphology and migration","volume":"9","author":"Bai","year":"2011","journal-title":"BMC Biol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0285","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1016\/j.celrep.2019.06.055","article-title":"The COMPASS family protein ASH2L mediates corticogenesis via transcriptional regulation of Wnt signaling","volume":"28","author":"Li","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbadis.2024.167097_bb0290","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2021.136015","article-title":"The role of PTEN signaling in synaptic function: implications in autism spectrum disorder","volume":"759","author":"Spina Nagy","year":"2021","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbadis.2024.167097_bb0295","first-page":"1","article-title":"RNA-sequencing and bioinformatics analysis of long noncoding RNAs and mRNAs in the prefrontal cortex of mice following repeated social defeat stress","volume":"2019","author":"Wang","year":"2019","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.bbadis.2024.167097_bb0300","series-title":"Oligophrenin-1 Encodes a rhoGAP Protein Involved in X-linked Mental Retardation","author":"Billuart","year":"1998"},{"key":"10.1016\/j.bbadis.2024.167097_bb0305","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1212\/01.wnl.0000182813.94713.ee","article-title":"Oligophrenin 1 mutations frequently cause X-linked mental retardation with cerebellar hypoplasia","volume":"65","author":"Zanni","year":"2005","journal-title":"Neurology"},{"key":"10.1016\/j.bbadis.2024.167097_bb0310","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/s13578-021-00726-x","article-title":"Autophagy deficiency in neurodevelopmental disorders","volume":"11","author":"Deng","year":"2021","journal-title":"Cell Biosci."},{"key":"10.1016\/j.bbadis.2024.167097_bb0315","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/s12929-023-00899-2","article-title":"The role of autophagy in viral infections","volume":"30","author":"Chen","year":"2023","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.bbadis.2024.167097_bb0320","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2018.00853","article-title":"The role of optineurin in antiviral type I interferon production","volume":"9","author":"Outlioua","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2024.167097_bb0325","doi-asserted-by":"crossref","DOI":"10.29399\/npa.21611","article-title":"Investigation of copy number variation by arrayCGH in Turkish children and adolescents diagnosed with autism spectrum disorders","author":"Gorker","year":"2018","journal-title":"Arch. Neuropsychiatry"},{"key":"10.1016\/j.bbadis.2024.167097_bb0330","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1002\/ajmg.b.30351","article-title":"Association study of polymorphisms in the glutamate transporter genes SLC1A1, SLC1A3, and SLC1A6 with schizophrenia","volume":"144B","author":"Deng","year":"2007","journal-title":"Am. J. Med. Genet. B Neuropsychiatr. Genet."},{"key":"10.1016\/j.bbadis.2024.167097_bb0335","doi-asserted-by":"crossref","DOI":"10.15252\/embj.201798280","article-title":"Glutamate transporter Slc1a3 mediates inter\u2010niche stem cell activation during skin growth","volume":"37","author":"Reichenbach","year":"2018","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2024.167097_bb0340","first-page":"599","article-title":"Cystine transporter SLC7A11\/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy, Protein","volume":"12","author":"Koppula","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.bbadis.2024.167097_bb0345","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1136\/jmedgenet-2015-103104","article-title":"Mutations in SLC1A4, encoding the brain serine transporter, are associated with developmental delay, microcephaly and hypomyelination","volume":"52","author":"Damseh","year":"2015","journal-title":"J. Med. Genet."},{"key":"10.1016\/j.bbadis.2024.167097_bb0350","doi-asserted-by":"crossref","DOI":"10.1111\/cge.12605","article-title":"A homozygous mutation in SLC1A4 in siblings with severe intellectual disability and microcephaly","volume":"88","author":"Srour","year":"2015","journal-title":"Clin. Genet."},{"key":"10.1016\/j.bbadis.2024.167097_bb0355","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1016\/j.envpol.2017.04.039","article-title":"The association of environmental toxicants and autism spectrum disorders in children","volume":"227","author":"Ye","year":"2017","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.bbadis.2024.167097_bb0360","doi-asserted-by":"crossref","first-page":"10695","DOI":"10.1523\/JNEUROSCI.2178-07.2007","article-title":"Maternal immune activation alters fetal brain development through interleukin-6","volume":"27","author":"Smith","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2024.167097_bb0365","doi-asserted-by":"crossref","first-page":"165","DOI":"10.3233\/HAB-180335","article-title":"Evaluation of antibodies to cytomegalovirus and Epstein-Barr virus in patients with autism spectrum disorder","volume":"26","author":"Valayi","year":"2017","journal-title":"Hum. Antib."},{"key":"10.1016\/j.bbadis.2024.167097_bb0370","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.bbi.2010.08.003","article-title":"Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome","volume":"25","author":"Ashwood","year":"2011","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbadis.2024.167097_bb0375","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1016\/j.neures.2006.06.002","article-title":"Recent progress in animal modeling of immune inflammatory processes in schizophrenia: implication of specific cytokines","volume":"56","author":"Nawa","year":"2006","journal-title":"Neurosci. Res."},{"key":"10.1016\/j.bbadis.2024.167097_bb0380","doi-asserted-by":"crossref","first-page":"2413","DOI":"10.1038\/s41436-019-0554-6","article-title":"Meta-analysis and multidisciplinary consensus statement: exome sequencing is a first-tier clinical diagnostic test for individuals with neurodevelopmental disorders","volume":"21","author":"Srivastava","year":"2019","journal-title":"Genet. Med."},{"key":"10.1016\/j.bbadis.2024.167097_bb0385","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.neuron.2015.09.016","article-title":"Insights into autism spectrum disorder genomic architecture and biology from 71 risk loci","volume":"87","author":"Sanders","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2024.167097_bb0390","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.ajhg.2018.07.006","article-title":"IRF2BPL Is associated with neurological phenotypes","volume":"103","author":"Marcogliese","year":"2018","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2024.167097_bb0395","article-title":"Childhood autism: translation and validation of the Childhood Autism Rating Scale for use in Brazil","author":"Pereira","year":"2008","journal-title":"J. Pediatr."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924000863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924000863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T12:19:30Z","timestamp":1748866770000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443924000863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":79,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S0925443924000863"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167097","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Zika virus infection impairs synaptogenesis, induces neuroinflammation, and could be an environmental risk factor for autism spectrum disorder outcome","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167097","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167097"}}