{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T16:42:48Z","timestamp":1786984968775,"version":"build-2736575974"},"reference-count":28,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,6,1]],"date-time":"2024-06-01T00:00:00Z","timestamp":1717200000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100005277","name":"Presbyterian Historical Society","doi-asserted-by":"publisher","award":["U01 DE017593"],"award-info":[{"award-number":["U01 DE017593"]}],"id":[{"id":"10.13039\/100005277","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005277","name":"Presbyterian Historical Society","doi-asserted-by":"publisher","award":["R03 DE 030990"],"award-info":[{"award-number":["R03 DE 030990"]}],"id":[{"id":"10.13039\/100005277","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008368","name":"Gigtforeningen","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008368","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100003392","name":"Sj\u00f6gren's Syndrome Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100003392","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2024,6]]},"DOI":"10.1016\/j.bbadis.2024.167168","type":"journal-article","created":{"date-parts":[[2024,4,17]],"date-time":"2024-04-17T11:51:13Z","timestamp":1713354673000},"page":"167168","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"title":["Seronegative patients with primary Sj\u00f6gren's syndrome and non-pSS sicca test positive for anti-SSA\/Ro52 and -Ro60 in saliva"],"prefix":"10.1016","volume":"1870","author":[{"given":"Sarah","family":"Kamounah","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin Kyun","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeong-Wook","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Chia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David T.W.","family":"Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Marie Lynge","family":"Pedersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2024.167168_bb0005","first-page":"3","article-title":"Sj\u00f6gren\u2019s syndrome: mechanisms of pathogenesis involve interaction of immune and neurosecretory systems","volume":"116","author":"Fox","year":"2002","journal-title":"Scand. J. Rheumatol. Suppl."},{"key":"10.1016\/j.bbadis.2024.167168_bb0010","doi-asserted-by":"crossref","first-page":"16047","DOI":"10.1038\/nrdp.2016.47","article-title":"Sj\u00f6gren syndrome","volume":"2","author":"Brito-Zer\u00f3n","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.bbadis.2024.167168_bb0015","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1056\/NEJMcp1702514","article-title":"Primary Sj\u00f6gren\u2019s syndrome","volume":"378","author":"Mariettte","year":"2018","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbadis.2024.167168_bb0020","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.jaut.2010.06.011","article-title":"The role of intrinsic epithelial activation in the pathogenesis of Sj\u00f6gren\u2019s syndrome","volume":"35","author":"Manoussakis","year":"2010","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2024.167168_bb0025","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/243723","article-title":"T regulatory and T helper 17 cells in primary Sj\u00f6gren\u2019s syndrome: facts and perspectives","volume":"2015","author":"Alunno","year":"2015","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.bbadis.2024.167168_bb0030","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.jaut.2012.01.002","article-title":"Pathogenesis of Sj\u00f6gren\u2019s syndrome: what we know and what we should learn","volume":"39","author":"Tzioufas","year":"2012","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2024.167168_bb0035","doi-asserted-by":"crossref","first-page":"2071","DOI":"10.2174\/138920112802273100","article-title":"B-lymphocytes govern the pathogenesis of Sj\u00f6gren\u2019s syndrome","volume":"13","author":"Youino","year":"2012","journal-title":"Curr. Pharm. Biotechnol."},{"key":"10.1016\/j.bbadis.2024.167168_bb0040","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1136\/ard.61.6.554","article-title":"European study group on classification criteria for Sj\u00f6gren\u2019s syndrome. Classification criteria for Sj\u00f6gren\u2019s syndrome: a revised version of the European criteria proposed by the American-European Consensus Group","volume":"61","author":"Vitali","year":"2002","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2024.167168_bb0045","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1002\/art.39859","volume":"69","author":"Shiboski","year":"2017","journal-title":"Arthritis Rheum."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167168_bb0050","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1002\/acr.21591","article-title":"American college of rheumatology classification criteria for Sj\u00f6gren\u2019s syndrome: a data-driven, expert consensus approach in the SICCA cohort","volume":"64","author":"Shiboski","year":"2012","journal-title":"Arthritis Care Res."},{"key":"10.1016\/j.bbadis.2024.167168_bb0055","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.rdc.2016.03.002","article-title":"Autoantibodies in Sj\u00f6gren\u2019s Syndrome","volume":"42","author":"Fayyaz","year":"2016","journal-title":"Rheum. Dis. Clin. N. Am."},{"key":"10.1016\/j.bbadis.2024.167168_bb0060","article-title":"Clinical and pathological roles of Ro\/SSA autoantibody system","volume":"60619512","author":"Yoshimi","year":"2012","journal-title":"Clin. Dev. Immunol."},{"issue":"10","key":"10.1016\/j.bbadis.2024.167168_bb0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0258428","article-title":"Combined serum anti-SSA\/Ro and salivary TRIM29 reveals promising high diagnostic accuracy in patients with primary Sj\u00f6gren\u2019s syndrome","volume":"16","author":"Sembler-M\u00f8ller","year":"2021","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2024.167168_bb0070","doi-asserted-by":"crossref","first-page":"444","DOI":"10.3389\/fimmu.2019.00444","article-title":"Diagnostic utility of separate anti-Ro60 and anti-Ro52\/TRIM21 antibody detection in autoimmune diseases","volume":"10","author":"Robbins","year":"2019","journal-title":"Front. Immunol."},{"issue":"12","key":"10.1016\/j.bbadis.2024.167168_bb0075","first-page":"2310","article-title":"The value of separate detection of anti-Ro52, anti-Ro60 and anti-SSB\/La reactivities in relation to diagnosis and phenotypes in primary Sj\u00f6gren\u2019s syndrome","volume":"40","author":"Deroo","year":"2022","journal-title":"Clin. Exp. Rheumatol."},{"issue":"5","key":"10.1016\/j.bbadis.2024.167168_bb0080","first-page":"686","article-title":"Anti-Ro52 antibody testing influences the classification and clinical characterisation of primary Sj\u00f6gren\u2019s syndrome","volume":"30","author":"Retamozo","year":"2012","journal-title":"Clin. Exp. Rheumatol."},{"issue":"9","key":"10.1016\/j.bbadis.2024.167168_bb0085","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1002\/acr.24597","article-title":"Antibodies to both Ro52 and Ro60 for identifying Sj\u00f6gren\u2019s syndrome patients best suited for clinical trials of disease-modifying therapies","volume":"74","author":"Arma\u011fan","year":"2022","journal-title":"Arthritis Care Res."},{"issue":"7","key":"10.1016\/j.bbadis.2024.167168_bb0090","doi-asserted-by":"crossref","first-page":"554","DOI":"10.4049\/immunohorizons.2300043","article-title":"Immunoassay detects salivary anti-SSA\/Ro-52 autoantibodies in seronegative patients with primary Sj\u00f6gren\u2019s syndrome","volume":"7","author":"Kamounah","year":"2023","journal-title":"Immunohorizons"},{"key":"10.1016\/j.bbadis.2024.167168_bb0095","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1111\/j.1601-0825.1999.tb00077.x","article-title":"Primary Sj\u00f6gren\u2019s syndrome: salivary gland function and clinical oral findings","volume":"5","author":"Pedersen","year":"1999","journal-title":"Oral Dis."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167168_bb0100","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1002\/art.1780270205","article-title":"Labial salivary gland biopsy in Sj\u00f6gren\u2019s syndrome. Assessment as a diagnostic criterion in 362 suspected cases","volume":"27","author":"Daniels","year":"1984","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbadis.2024.167168_bb0105","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1002\/art.39214","article-title":"Prediction of Sj\u00f6gren\u2019s syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling","volume":"67","author":"Theander","year":"2015","journal-title":"Arthritis Rheum."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167168_bb0110","doi-asserted-by":"crossref","first-page":"471","DOI":"10.1007\/BF02231773","article-title":"Anti-SSA\/Ro and anti-SSB\/La antibodies in serum and saliva of patients with Sjogren\u2019s syndrome","volume":"12","author":"Ben-Chetrit","year":"1993","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.bbadis.2024.167168_bb0115","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/0022034510390811","article-title":"Salivary anti-Ro60 and anti-Ro52 antibody profiles to diagnose Sj\u00f6gren\u2019s syndrome","volume":"90","author":"Ching","year":"2011","journal-title":"J. Dent. Res."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167168_bb0120","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/030097400750001752","article-title":"Isotype distribution of anti-Ro\/SS-A and anti-La\/SS-B antibodies in plasma and saliva of patients with Sj\u00f6gren\u2019s syndrome","volume":"29","author":"Halse","year":"2000","journal-title":"Scand. J. Rheumatol."},{"key":"10.1016\/j.bbadis.2024.167168_bb0125","doi-asserted-by":"crossref","first-page":"16047","DOI":"10.1038\/nrdp.2016.47","article-title":"Sj\u00f6gren syndrome","volume":"2","author":"Brito-Zer\u00f3n","year":"2016","journal-title":"Nat. Rev. Dis. Primers"},{"key":"10.1016\/j.bbadis.2024.167168_bb0130","doi-asserted-by":"crossref","first-page":"2223","DOI":"10.1093\/rheumatology\/ket295","article-title":"Anti-SSA Ro52\/Ro60 antibody testing by immunodot could help the diagnosis of Sj\u00f6gren\u2019s syndrome in the absence of anti-SSA\/SSB antibodies by ELISA","volume":"52","author":"Mekinian","year":"2013","journal-title":"Rheumatology (Oxford)"},{"key":"10.1016\/j.bbadis.2024.167168_bb0135","article-title":"Clinical and pathological roles of Ro\/SSA autoantibody system","volume":"606195","author":"Yoshimi","year":"2012","journal-title":"Clin. Dev. Immunol."},{"issue":"7","key":"10.1016\/j.bbadis.2024.167168_bb0140","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.autrev.2009.02.010","article-title":"Latest update on the Ro\/SS-A autoantibody system","volume":"8","author":"Schulte-Pelkum","year":"2009","journal-title":"Autoimmun. Rev."}],"updated-by":[{"DOI":"10.1016\/j.bbadis.2024.167474","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000}}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924001571?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924001571?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T06:22:46Z","timestamp":1762323766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443924001571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6]]},"references-count":28,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,6]]}},"alternative-id":["S0925443924001571"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167168","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Seronegative patients with primary Sj\u00f6gren's syndrome and non-pSS sicca test positive for anti-SSA\/Ro52 and -Ro60 in saliva","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167168","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167168"}}