{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:41:41Z","timestamp":1791222101664,"version":"4.1.0"},"reference-count":61,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,2,1]],"date-time":"2025-02-01T00:00:00Z","timestamp":1738368000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2025,2]]},"DOI":"10.1016\/j.bbadis.2024.167579","type":"journal-article","created":{"date-parts":[[2024,11,18]],"date-time":"2024-11-18T02:48:48Z","timestamp":1731898128000},"page":"167579","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"title":["Sanguinarine chloride hydrate mitigates colitis symptoms in mice through the regulation of the intestinal microbiome and metabolism of short-chain fatty acids"],"prefix":"10.1016","volume":"1871","author":[{"given":"Jige","family":"Xin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanlin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiqi","family":"Pu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuan","family":"Du","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuze","family":"Ban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2145-3706","authenticated-orcid":false,"given":"Diangang","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0005","doi-asserted-by":"crossref","first-page":"26","DOI":"10.5217\/ir.2018.16.1.26","article-title":"Immunological pathogenesis of inflammatory bowel disease","volume":"16","author":"Lee","year":"2018","journal-title":"Intest. Res."},{"key":"10.1016\/j.bbadis.2024.167579_bb0010","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/718617","article-title":"Dextran sodium sulphate colitis mouse model: traps and tricks","volume":"2012","author":"Per\u0161e","year":"2012","journal-title":"J. Biomed. Biotechnol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0015","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0202929","article-title":"Preventive effects of bovine colostrum supplementation in TNBS-induced colitis in mice","volume":"13","author":"Filipescu","year":"2018","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2024.167579_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.bcp.2016.03.009","article-title":"TRAF2 multitasking in TNF receptor-induced signaling to NF-\u03baB, MAP kinases and cell death","volume":"116","author":"Borghi","year":"2016","journal-title":"Biochem. Pharmacol."},{"issue":"8","key":"10.1016\/j.bbadis.2024.167579_bb0025","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1038\/s41579-018-0036-x","article-title":"Interactions of commensal and pathogenic microorganisms with the intestinal mucosal barrier","volume":"16","author":"Martens","year":"2018","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0030","doi-asserted-by":"crossref","first-page":"10697","DOI":"10.1021\/acs.jafc.0c04370","article-title":"Sesamol supplementation attenuates DSS-induced colitis via mediating gut barrier integrity, inflammatory responses, and reshaping gut microbiome","volume":"68","author":"Zhao","year":"2020","journal-title":"J. Agric. Food Chem."},{"issue":"2","key":"10.1016\/j.bbadis.2024.167579_bb0035","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/s41564-018-0306-4","article-title":"Gut microbiome structure and metabolic activity in inflammatory bowel disease","volume":"4","author":"Franzosa","year":"2019","journal-title":"Nat. Microbiol."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0040","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.mayocp.2018.09.013","article-title":"Mechanisms of disease: inflammatory bowel diseases","volume":"94","author":"Ramos","year":"2019","journal-title":"Mayo Clin. Proc."},{"issue":"3","key":"10.1016\/j.bbadis.2024.167579_bb0045","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1093\/ecco-jcc\/jjx153","article-title":"Characteristics of faecal microbiota in paediatric crohn\u2019s disease and their dynamic changes during infliximab therapy","volume":"12","author":"Wang","year":"2018","journal-title":"J. Crohns Colitis"},{"issue":"6","key":"10.1016\/j.bbadis.2024.167579_bb0050","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1038\/s41574-019-0205-7","article-title":"SCFAs - the thin microbial metabolic line between good and bad","volume":"15","author":"Serino","year":"2019","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0055","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/j.ebiom.2019.09.008","article-title":"Mucin o-glycans facilitate symbiosynthesis to maintain gut immune homeostasis","volume":"48","author":"Yamada","year":"2019","journal-title":"EBioMedicine"},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0060","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/ptr.5952","article-title":"Medicinal plants of the genus Macleaya (Macleaya cordata, Macleaya microcarpa): a review of their phytochemistry, pharmacology, and toxicology","volume":"32","author":"Lin","year":"2018","journal-title":"Phytother. Res."},{"key":"10.1016\/j.bbadis.2024.167579_bb0065","doi-asserted-by":"crossref","first-page":"1175227","DOI":"10.3389\/fphys.2023.1175227","article-title":"Potential pharmacological mechanisms of four active compounds of Macleaya cordata extract against enteritis based on network pharmacology and molecular docking technology","volume":"14","author":"Yang","year":"2023","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0070","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2022.935201","article-title":"Exploring the anti-inflammatory effects of protopine total alkaloids of Macleaya cordata (willd.) R. Br","volume":"9","author":"Dong","year":"2022","journal-title":"Front. Vet. Sci."},{"key":"10.1016\/j.bbadis.2024.167579_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154164","volume":"102","author":"Ma","year":"2022","journal-title":"Phytomedicine"},{"issue":"24","key":"10.1016\/j.bbadis.2024.167579_bb0080","doi-asserted-by":"crossref","first-page":"2760","DOI":"10.2174\/1381612824666180829100601","article-title":"The anticancer effect of sanguinarine: a review","volume":"24","author":"Fu","year":"2018","journal-title":"Curr. Pharm. Des."},{"key":"10.1016\/j.bbadis.2024.167579_bb0085","article-title":"Natural antibacterial and antivirulence alkaloids from Macleaya cordata against methicillin-resistant Staphylococcus aureus","volume":"13","author":"Liu","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0090","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13020-024-00881-6","article-title":"Sanguinarine chloride induces ferroptosis by regulating ROS\/BACH1\/HMOX1 signaling pathway in prostate cancer","volume":"19","author":"Liu","year":"2024","journal-title":"Chin. Med."},{"key":"10.1016\/j.bbadis.2024.167579_bb0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154321","article-title":"Sanguinarine ameliorates DSS-induced ulcerative colitis by inhibiting NLRP3 inflammasome activation and modulating intestinal microbiota in C57BL\/6 mice","volume":"104","author":"Li","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbadis.2024.167579_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2021.112496","article-title":"Preventive effect of sanguinarine on intestinal injury in mice exposed to whole abdominal irradiation","volume":"146","author":"Gu","year":"2022","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0105","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1080\/15548627.2019.1635384","article-title":"New insights into the interplay between autophagy, gut microbiota and inflammatory responses in IBD","volume":"16","author":"Larabi","year":"2020","journal-title":"Autophagy"},{"issue":"19","key":"10.1016\/j.bbadis.2024.167579_bb0110","doi-asserted-by":"crossref","first-page":"3567","DOI":"10.2174\/0929867324666170428103848","article-title":"The food-gut human axis: the effects of diet on gut microbiota and metabolome","volume":"26","author":"De Angelis","year":"2019","journal-title":"Curr. Med. Chem."},{"key":"10.1016\/j.bbadis.2024.167579_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2019.104489","article-title":"Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota","volume":"150","author":"Wu","year":"2019","journal-title":"Pharmacol. Res."},{"issue":"13","key":"10.1016\/j.bbadis.2024.167579_bb0120","doi-asserted-by":"crossref","first-page":"5277","DOI":"10.3390\/molecules28135277","article-title":"Protopine alleviates dextran sodium sulfate-induced ulcerative colitis by improving intestinal barrier function and regulating intestinal microbiota","volume":"28","author":"Yue","year":"2023","journal-title":"Molecules"},{"issue":"11","key":"10.1016\/j.bbadis.2024.167579_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2020.e05361","article-title":"Influence of sanguinarine-based phytobiotic supplementation on post necrotic enteritis challenge recovery","volume":"6","author":"Aljumaah","year":"2020","journal-title":"Heliyon"},{"key":"10.1016\/j.bbadis.2024.167579_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2021.153631","article-title":"Dihydroberberine, an isoquinoline alkaloid, exhibits protective effect against dextran sulfate sodium-induced ulcerative colitis in mice","volume":"90","author":"Li","year":"2021","journal-title":"Phytomedicine"},{"issue":"5","key":"10.1016\/j.bbadis.2024.167579_bb0135","doi-asserted-by":"crossref","first-page":"1069","DOI":"10.3390\/nu14051069","article-title":"Taxifolin alleviates DSS-induced ulcerative colitis by acting on gut microbiome to produce butyric acid","volume":"14","author":"Li","year":"2022","journal-title":"Nutrients"},{"key":"10.1016\/j.bbadis.2024.167579_bb0140","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.798052","article-title":"Supplementation with chinese medicinal plant extracts from lonicera hypoglauca and scutellaria baicalensis mitigates colonic inflammation by regulating oxidative stress and gut microbiota in a colitis mouse model","volume":"11","author":"Wan","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"12","key":"10.1016\/j.bbadis.2024.167579_bb0145","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.lfs.2013.01.028","article-title":"Efficacy of drugs used in the treatment of IBD and combinations thereof in acute DSS-induced colitis in mice","volume":"92","author":"Sann","year":"2013","journal-title":"Life Sci."},{"key":"10.1016\/j.bbadis.2024.167579_bb0150","doi-asserted-by":"crossref","first-page":"41427","DOI":"10.1021\/acsomega.3c05159","article-title":"Virofree associates with the modulation of gut microbiomes and alleviation of DSS-induced IBD symptoms in mice","volume":"8","author":"Lin","year":"2023","journal-title":"ACS Omega"},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0155","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1111\/asj.12240","article-title":"Effect of a natural feed additive (Macleaya cordata), containing sanguinarine, on the performance and health status of weaning pigs","volume":"J86","author":"Kantas","year":"2015","journal-title":"Anim. Sci. J."},{"key":"10.1016\/j.bbadis.2024.167579_bb0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2022.114148","article-title":"Dietary lactate supplementation can alleviate DSS-induced colitis in piglets","volume":"158","author":"Wang","year":"2023","journal-title":"Biomed. Pharmacother."},{"issue":"11","key":"10.1016\/j.bbadis.2024.167579_bb0165","doi-asserted-by":"crossref","first-page":"6013","DOI":"10.1016\/j.psj.2020.06.078","article-title":"The posthatch prophylactic use of ceftiofur affects the cecal microbiota similar to the dietary sanguinarine supplementation in broilers","volume":"99","author":"Lemos","year":"2020","journal-title":"Poult. Sci."},{"issue":"20","key":"10.1016\/j.bbadis.2024.167579_bb0170","doi-asserted-by":"crossref","first-page":"2875","DOI":"10.3390\/ani12202875","article-title":"Assessing performance and safety of feeding a standardized Macleaya cordata extract to calves","volume":"12","author":"Matulka","year":"2022","journal-title":"Animals (Basel)"},{"key":"10.1016\/j.bbadis.2024.167579_bb0175","doi-asserted-by":"crossref","DOI":"10.3389\/fvets.2023.1121082","article-title":"Antibacterial activity and mechanism of sanguinarine against Staphylococcus aureus by interfering with the permeability of the cell wall and membrane and inducing bacterial ROS production","volume":"10","author":"Gu","year":"2023","journal-title":"Front. Vet. Sci."},{"issue":"5","key":"10.1016\/j.bbadis.2024.167579_bb0180","doi-asserted-by":"crossref","first-page":"1073","DOI":"10.3390\/foods12051073","article-title":"Blackcurrant alleviates dextran sulfate sodium (DSS)-induced colitis in mice","volume":"12","author":"Moon","year":"2023","journal-title":"Foods"},{"issue":"7152","key":"10.1016\/j.bbadis.2024.167579_bb0185","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/nature06005","article-title":"Unravelling the pathogenesis of inflammatory bowel disease","volume":"448","author":"Xavier","year":"2007","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.bbadis.2024.167579_bb0190","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.taap.2013.01.009","article-title":"Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice","volume":"267","author":"Niu","year":"2013","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2022.154217","article-title":"Berberine regulates short-chain fatty acid metabolism and alleviates the colitis-associated colorectal tumorigenesis through remodeling intestinal flora","volume":"102","author":"Yan","year":"2022","journal-title":"Phytomedicine"},{"key":"10.1016\/j.bbadis.2024.167579_bb0200","doi-asserted-by":"crossref","unstructured":"Meng Y.Y., Liu Y., Hu Z.F., Zhang Y., Ni J., Ma Z.G., et al. Sanguinarine attenuates lipopolysaccharide-induced inflammation and apoptosis by inhibiting the TLR4\/NF-\u03baB pathway in H9c2 cardiomyocytes. Curr. Med. Sci. 38(2), 204\u2013211. doi:https:\/\/doi.org\/10.1007\/s11596-018-1867-4.","DOI":"10.1007\/s11596-018-1867-4"},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0205","doi-asserted-by":"crossref","DOI":"10.1111\/asj.13357","article-title":"Regulation of the intestinal barrier by nutrients: the role of tight junctions","volume":"91","author":"Suzuki","year":"2020","journal-title":"Anim. Sci. J."},{"key":"10.1016\/j.bbadis.2024.167579_bb0210","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.phrs.2017.04.017","article-title":"Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism","volume":"121","author":"Qu","year":"2017","journal-title":"Pharmacol. Res."},{"issue":"3","key":"10.1016\/j.bbadis.2024.167579_bb0215","doi-asserted-by":"crossref","first-page":"151","DOI":"10.5625\/lar.2016.32.3.151","article-title":"Fermented pueraria lobata extract ameliorates dextran sulfate sodium-induced colitis by reducing pro-inflammatory cytokines and recovering intestinal barrier function","volume":"32","author":"Choi","year":"2016","journal-title":"Lab. Anim. Res."},{"issue":"1","key":"10.1016\/j.bbadis.2024.167579_bb0220","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1093\/ibd\/izy281","article-title":"Bacteroides the taiotaomicron ameliorates colon inflammation in preclinical models of crohn\u2019s disease","volume":"25","author":"Delday","year":"2019","journal-title":"Inflamm. Bowel Dis."},{"issue":"4","key":"10.1016\/j.bbadis.2024.167579_bb0225","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1080\/19490976.2018.1560753","article-title":"Bacteroides ovatus ATCC 8483 monotherapy is superior to traditional fecal transplant and multi-strain bacteriotherapy in a murine colitis model","volume":"10","author":"Ihekweazu","year":"2019","journal-title":"Gut Microbes"},{"key":"10.1016\/j.bbadis.2024.167579_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.934695","article-title":"Akkermansia muciniphila and gut immune system: a good friendship that attenuates inflammatory bowel disease, obesity, and diabetes","volume":"13","author":"Rodrigues","year":"2022","journal-title":"Front. Immunol."},{"issue":"47","key":"10.1016\/j.bbadis.2024.167579_bb0235","doi-asserted-by":"crossref","first-page":"14864","DOI":"10.1021\/acs.jafc.2c06417","article-title":"Fucoidan ameliorated dextran sulfate sodium-induced ulcerative colitis by modulating gut microbiota and bile acid metabolism","volume":"70","author":"Liu","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbadis.2024.167579_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2023.112630","article-title":"Alleviative effects of natural plant polysaccharides against DSS-induced ulcerative colitis via inhibiting inflammation and modulating gut microbiota","volume":"167","author":"Lu","year":"2023","journal-title":"Food Res. Int."},{"issue":"42","key":"10.1016\/j.bbadis.2024.167579_bb0245","doi-asserted-by":"crossref","first-page":"15604","DOI":"10.1021\/acs.jafc.3c04220","article-title":"Walnut protein peptides ameliorate DSS-induced ulcerative colitis damage in mice: An in silico analysis and in vivo investigation","volume":"71","author":"Hong","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbadis.2024.167579_bb0250","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.728929","article-title":"Pulsatilla chinensis saponins ameliorate inflammation and DSS-induced ulcerative colitis in rats by regulating the composition and diversity of intestinal flora","volume":"11","author":"Liu","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"9","key":"10.1016\/j.bbadis.2024.167579_bb0255","doi-asserted-by":"crossref","first-page":"7817","DOI":"10.1039\/D0FO01418D","article-title":"Grape seed proanthocyanidin extract ameliorates dextran sulfate sodium-induced colitis through intestinal barrier improvement, oxidative stress reduction, and inflammatory cytokines and gut microbiota modulation","volume":"11","author":"Sheng","year":"2020","journal-title":"Food Funct."},{"key":"10.1016\/j.bbadis.2024.167579_bb0260","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3389\/fimmu.2019.00277","article-title":"Short chain fatty acids (SCFAs)-mediated gut epithelial and immune regulation and its relevance for inflammatory bowel diseases","volume":"10","author":"Parada","year":"2019","journal-title":"Front. Immunol."},{"issue":"3","key":"10.1016\/j.bbadis.2024.167579_bb0265","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1080\/19490976.2015.1134082","article-title":"Formation of short chain fatty acids by the gut microbiota and their impact on human metabolism","volume":"7","author":"Morrison","year":"2016","journal-title":"Gut Microbes"},{"issue":"Pt 1","key":"10.1016\/j.bbadis.2024.167579_bb0270","article-title":"Sporisorium reilianum polysaccharides improve DSS-induced ulcerative colitis by regulating intestinal barrier function and metabolites","volume":"265","author":"Liu","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"8","key":"10.1016\/j.bbadis.2024.167579_bb0275","doi-asserted-by":"crossref","first-page":"4109","DOI":"10.1039\/D4FO00835A","article-title":"Riboflavin ameliorates intestinal inflammation via immune modulation and alterations of gut microbiota homeostasis in DSS-colitis C57BL\/6 mice","volume":"15","author":"Zhang","year":"2024","journal-title":"Food Funct."},{"issue":"7","key":"10.1016\/j.bbadis.2024.167579_bb0280","doi-asserted-by":"crossref","first-page":"2241","DOI":"10.1021\/acs.jafc.1c07568","article-title":"Hydroxytyrosol alleviates dextran sulfate sodium-induced colitis by modulating inflammatory responses, intestinal barrier, and microbiome","volume":"70","author":"Wang","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bbadis.2024.167579_bb0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2022.109097","article-title":"Natural shikonin and acetyl-shikonin improve intestinal microbial and protein composition to alleviate colitis-associated colorectal cancer","volume":"111","author":"Lin","year":"2022","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bbadis.2024.167579_bb0290","article-title":"Macleaya cordata extract improves growth performance, immune responses and anti-inflammatory capacity in neonatal piglets","volume":"293","author":"Han","year":"2022","journal-title":"Vet. Microbiol."},{"issue":"19","key":"10.1016\/j.bbadis.2024.167579_bb0295","doi-asserted-by":"crossref","first-page":"10171","DOI":"10.1039\/D2FO02303B","article-title":"Lactobacillus plantarum HNU082 alleviates dextran sulfate sodium-induced ulcerative colitis in mice through regulating gut microbiome","volume":"13","author":"Wu","year":"2022","journal-title":"Food Funct."},{"key":"10.1016\/j.bbadis.2024.167579_bb0300","article-title":"Prebiotics for induction and maintenance of remission in ulcerative colitis","volume":"3(3):CD015084","author":"Sinopoulou","year":"2024","journal-title":"Cochrane Database Syst. Rev."},{"issue":"16","key":"10.1016\/j.bbadis.2024.167579_bb0305","doi-asserted-by":"crossref","first-page":"2100","DOI":"10.2174\/1871520621666210126091512","article-title":"Sanguinarine: a double-edged sword of anticancer and carcinogenesis and its future application prospect","volume":"21","author":"Lou","year":"2021","journal-title":"Anti Cancer Agents Med. Chem."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924005738?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443924005738?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T05:05:36Z","timestamp":1769922336000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443924005738"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":61,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2]]}},"alternative-id":["S0925443924005738"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167579","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Sanguinarine chloride hydrate mitigates colitis symptoms in mice through the regulation of the intestinal microbiome and metabolism of short-chain fatty acids","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2024.167579","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167579"}}