{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T23:34:52Z","timestamp":1792020892953,"version":"4.4.0"},"reference-count":76,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T00:00:00Z","timestamp":1741046400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.bbadis.2025.167767","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:43:20Z","timestamp":1741128200000},"page":"167767","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Red blood cell proteomic profiling in mild and severe obstructive sleep apnea patients before and after positive airway pressure treatment"],"prefix":"10.1016","volume":"1871","author":[{"given":"Cristina","family":"Valentim-Coelho","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joana","family":"Saraiva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"Os\u00f3rio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00edlia","family":"Antunes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F\u00e1tima","family":"Vaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sofia","family":"Neves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Pinto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"B\u00e1rbara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah","family":"Penque","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2025.167767_bb0005","first-page":"687","article-title":"Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis, lancet","volume":"7","author":"Benjafield","year":"2019","journal-title":"Respir. Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0010","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.3390\/antiox9121184","article-title":"Redox\u2013oligomeric state of peroxiredoxin-2 and glyceraldehyde-3-phosphate dehydrogenase in obstructive sleep apnea red blood cells under positive airway pressure therapy","volume":"9","author":"Valentim-Coelho","year":"2020","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbadis.2025.167767_bb0015","doi-asserted-by":"crossref","DOI":"10.7326\/AITC201912030","article-title":"Obstructive sleep apnea","volume":"171","author":"Patel","year":"2019","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0020","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1186\/s40248-019-0186-3","article-title":"Long term management of obstructive sleep apnea and its comorbidities","volume":"14","author":"Marin-Oto","year":"2019","journal-title":"Multidiscip. Respir. Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0025","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s00408-021-00426-w","article-title":"Evaluation and management of adults with obstructive sleep apnea syndrome","volume":"199","author":"Lee","year":"2021","journal-title":"Lung"},{"key":"10.1016\/j.bbadis.2025.167767_bb0030","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1055\/s-0036-1579546","article-title":"Comorbidities associated with obstructive sleep apnea: a retrospective study","volume":"20","author":"Pinto","year":"2016","journal-title":"Int Arch Otorhinolaryngol"},{"key":"10.1016\/j.bbadis.2025.167767_bb0035","doi-asserted-by":"crossref","first-page":"E1112","DOI":"10.21037\/jtd.2016.09.67","article-title":"When continuous positive airway pressure (CPAP) fails","volume":"8","author":"Virk","year":"2016","journal-title":"J. Thorac. Dis."},{"key":"10.1016\/j.bbadis.2025.167767_bb0040","doi-asserted-by":"crossref","first-page":"159","DOI":"10.2147\/NSS.S164488","article-title":"Use of blood biomarkers to screen for obstructive sleep apnea","volume":"10","author":"Fleming","year":"2018","journal-title":"Nat Sci Sleep"},{"key":"10.1016\/j.bbadis.2025.167767_bb0045","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1080\/14789450.2018.1531710","article-title":"Red blood cells as an organ? How deep omics characterization of the most abundant cell in the human body highlights other systemic metabolic functions beyond oxygen transport","volume":"15","author":"Nemkov","year":"2018","journal-title":"Expert Rev Proteomics"},{"key":"10.1016\/j.bbadis.2025.167767_bb0050","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.3390\/antiox12091736","article-title":"The reactive species interactome in red blood cells: oxidants, antioxidants, and molecular targets","volume":"12","author":"Cortese-Krott","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbadis.2025.167767_bb0055","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.freeradbiomed.2021.03.020","article-title":"Novel perspectives on redox signaling in red blood cells and platelets in cardiovascular disease","volume":"168","author":"Mahdi","year":"2021","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0060","doi-asserted-by":"crossref","first-page":"718","DOI":"10.1089\/ars.2016.6954","article-title":"Red blood cell function and dysfunction: redox regulation, nitric oxide metabolism, anemia","volume":"26","author":"Kuhn","year":"2017","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbadis.2025.167767_bb0065","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/j.bbadis.2016.11.019","article-title":"Evening and morning peroxiredoxin-2 redox\/oligomeric state changes in obstructive sleep apnea red blood cells: correlation with polysomnographic and metabolic parameters","volume":"1863","author":"Feliciano","year":"2017","journal-title":"Biochim. Biophys. Acta (BBA) - Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2025.167767_bb0070","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.dib.2017.01.005","article-title":"Evening and morning alterations in Obstructive Sleep Apnea red blood cell proteome","volume":"11","author":"Feliciano","year":"2017","journal-title":"Data Brief"},{"key":"10.1016\/j.bbadis.2025.167767_bb0075","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.sleep.2014.11.014","article-title":"Overview of proteomics studies in obstructive sleep apnea","volume":"16","author":"Feliciano","year":"2015","journal-title":"Sleep Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0080","doi-asserted-by":"crossref","first-page":"1367","DOI":"10.1038\/nbt.1511","article-title":"MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification","volume":"26","author":"Cox","year":"2008","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0085","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nmeth.3901","article-title":"The Perseus computational platform for comprehensive analysis of (prote)omics data","volume":"13","author":"Tyanova","year":"2016","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbadis.2025.167767_bb0090","doi-asserted-by":"crossref","first-page":"W216","DOI":"10.1093\/nar\/gkac194","article-title":"DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)","volume":"50","author":"Sherman","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbadis.2025.167767_bb0095","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v082.i13","article-title":"lmerTest package: tests in linear mixed effects models","volume":"82","author":"Kuznetsova","year":"2017","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.bbadis.2025.167767_bb0100","doi-asserted-by":"crossref","DOI":"10.18637\/jss.v067.i01","article-title":"Fitting linear mixed-effects models using lme4","volume":"67","author":"Bates","year":"2015","journal-title":"J. Stat. Softw."},{"key":"10.1016\/j.bbadis.2025.167767_bb0105","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1080\/00031305.1980.10483031","article-title":"Population marginal means in the linear model: an alternative to least squares means","volume":"34","author":"Searle","year":"1980","journal-title":"Am. Stat."},{"key":"10.1016\/j.bbadis.2025.167767_bb0110","first-page":"626","article-title":"Rectangular confidence regions for the means of multivariate normal distributions","volume":"62","author":"Sidak","year":"1967","journal-title":"J. Am. Stat. Assoc."},{"key":"10.1016\/j.bbadis.2025.167767_bb0115","series-title":"ggplot2","author":"Wickham","year":"2016"},{"key":"10.1016\/j.bbadis.2025.167767_bb0120","doi-asserted-by":"crossref","first-page":"1686","DOI":"10.21105\/joss.01686","article-title":"Welcome to the Tidyverse","volume":"4","author":"Wickham","year":"2019","journal-title":"J Open Source Softw"},{"key":"10.1016\/j.bbadis.2025.167767_bb0125","author":"Wickham"},{"key":"10.1016\/j.bbadis.2025.167767_bb0130","doi-asserted-by":"crossref","first-page":"3379","DOI":"10.3390\/ijms20143379","article-title":"Cellular responses to proteasome inhibition: molecular mechanisms and beyond","volume":"20","author":"Albornoz","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.167767_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.104862","article-title":"\u0397igh-resolution structure of mammalian PI31\u201320S proteasome complex reveals mechanism of proteasome inhibition","volume":"299","author":"Hsu","year":"2023","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.167767_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.111103","article-title":"The protein organization of a red blood cell","volume":"40","author":"Sae-Lee","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbadis.2025.167767_bb0145","doi-asserted-by":"crossref","first-page":"277","DOI":"10.3390\/jcm10020277","article-title":"Oxidative stress and inflammation biomarker expression in obstructive sleep apnea patients","volume":"10","author":"Maniaci","year":"2021","journal-title":"J. Clin. Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0150","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/9681595","article-title":"Oxidative stress markers among obstructive sleep apnea patients","volume":"2021","author":"Stanek","year":"2021","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbadis.2025.167767_bb0155","doi-asserted-by":"crossref","first-page":"3159","DOI":"10.1096\/fj.09-130666","article-title":"Hypoxia limits antioxidant capacity in red blood cells by altering glycolytic pathway dominance","volume":"23","author":"Rogers","year":"2009","journal-title":"FASEB J."},{"key":"10.1016\/j.bbadis.2025.167767_bb0160","first-page":"535","article-title":"Purinergic control of red blood cell metabolism: novel strategies to improve red cell storage quality","volume":"15","author":"Sun","year":"2017","journal-title":"Blood Transfus."},{"key":"10.1016\/j.bbadis.2025.167767_bb0165","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/j.molcel.2015.06.017","article-title":"Acute activation of oxidative pentose phosphate pathway as first-line response to oxidative stress in human skin cells","volume":"59","author":"Kuehne","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbadis.2025.167767_bb0170","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1016\/j.molcel.2015.08.002","article-title":"Metabolic remodeling in times of stress: who shoots faster than his shadow?","volume":"59","author":"Dick","year":"2015","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbadis.2025.167767_bb0175","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/s42255-023-00781-3","article-title":"The GAPDH redox switch safeguards reductive capacity and enables survival of stressed tumour cells","volume":"5","author":"Talwar","year":"2023","journal-title":"Nat. Metab."},{"key":"10.1016\/j.bbadis.2025.167767_bb0180","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.semcdb.2015.08.004","article-title":"Pyruvate kinase: function, regulation and role in cancer","volume":"43","author":"Israelsen","year":"2015","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0185","doi-asserted-by":"crossref","first-page":"2577","DOI":"10.1007\/s00018-013-1539-2","article-title":"Regulation of pyruvate metabolism and human disease","volume":"71","author":"Gray","year":"2014","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbadis.2025.167767_bb0190","doi-asserted-by":"crossref","first-page":"4034","DOI":"10.1182\/blood-2005-04-1622","article-title":"The energy-less red blood cell is lost: erythrocyte enzyme abnormalities of glycolysis","volume":"106","author":"van Wijk","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.bbadis.2025.167767_bb0195","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/sbr.12078","article-title":"Metabolic dysfunction in obstructive sleep apnea: a critical examination of underlying mechanisms","volume":"13","author":"Mesarwi","year":"2015","journal-title":"Sleep Biol. Rhythms"},{"key":"10.1016\/j.bbadis.2025.167767_bb0200","doi-asserted-by":"crossref","first-page":"279","DOI":"10.5664\/jcsm.9628","article-title":"OSA and cardiorespiratory fitness: a review","volume":"18","author":"Powell","year":"2022","journal-title":"J. Clin. Sleep Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0205","doi-asserted-by":"crossref","first-page":"3883","DOI":"10.1021\/acs.jproteome.6b00733","article-title":"AltitudeOmics: red blood cell metabolic adaptation to high altitude hypoxia","volume":"15","author":"D\u2019Alessandro","year":"2016","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbadis.2025.167767_bb0210","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1017\/S1755254010000176","article-title":"The lactate paradox: a review","volume":"7","author":"Bartlett","year":"2010","journal-title":"Comp Exerc Physiol"},{"key":"10.1016\/j.bbadis.2025.167767_bb0215","doi-asserted-by":"crossref","first-page":"3981","DOI":"10.7150\/ijbs.63556","article-title":"Enolase 1, a moonlighting protein, as a potential target for cancer treatment","volume":"17","author":"Qiao","year":"2021","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bbadis.2025.167767_bb0220","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1513\/AnnalsATS.202108-960OC","article-title":"Obstructive sleep apnea and lung cancer: a systematic review and meta-analysis","volume":"19","author":"Cheong","year":"2022","journal-title":"Ann. Am. Thorac. Soc."},{"key":"10.1016\/j.bbadis.2025.167767_bb0225","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.130232","article-title":"Inhibition of triosephosphate isomerase by phosphoenolpyruvate in the feedback-regulation of glycolysis","volume":"4","author":"Gr\u00fcning","year":"2014","journal-title":"Open Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0230","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1096\/fj.00-0823hyp","article-title":"NAD(P)H, a directly operating antioxidant?","volume":"15","author":"Kirsch","year":"2001","journal-title":"FASEB J."},{"key":"10.1016\/j.bbadis.2025.167767_bb0235","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/brv.12140","article-title":"The return of metabolism: biochemistry and physiology of the pentose phosphate pathway","volume":"90","author":"Stincone","year":"2015","journal-title":"Biol. Rev."},{"key":"10.1016\/j.bbadis.2025.167767_bb0240","doi-asserted-by":"crossref","DOI":"10.1111\/apha.14081","article-title":"Erythrocyte metabolism","volume":"240","author":"Chatzinikolaou","year":"2024","journal-title":"Acta Physiol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0245","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.2298\/VSP161030041C","article-title":"Impact of severity of obstructive sleep apnea (OSA) and body composition on redox status in OSA patients","volume":"75","author":"Cekerevac","year":"2018","journal-title":"Vojnosanit. Pregl."},{"key":"10.1016\/j.bbadis.2025.167767_bb0250","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/8857906","article-title":"Downregulated recycling process but not de novo synthesis of glutathione limits antioxidant capacity of erythrocytes in hypoxia","volume":"2020","author":"Wang","year":"2020","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.bbadis.2025.167767_bb0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.redox.2022.102535","article-title":"Hemoglobin is an oxygen-dependent glutathione buffer adapting the intracellular reduced glutathione levels to oxygen availability","volume":"58","author":"Fenk","year":"2022","journal-title":"Redox Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0260","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2021.763933","article-title":"Influence of high hemoglobin-oxygen affinity on humans during hypoxia","volume":"12","author":"Webb","year":"2022","journal-title":"Front. Physiol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0265","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1161\/CIRCULATIONAHA.116.021311","article-title":"Beneficial role of erythrocyte adenosine A2B receptor\u2013mediated AMP-activated protein kinase activation in high-altitude hypoxia","volume":"134","author":"Liu","year":"2016","journal-title":"Circulation"},{"key":"10.1016\/j.bbadis.2025.167767_bb0270","doi-asserted-by":"crossref","DOI":"10.1242\/jeb.185470","article-title":"Allosteric mechanisms underlying the adaptive increase in hemoglobin-oxygen affinity of the bar-headed goose","author":"Jendroszek","year":"2018","journal-title":"J. Exp. Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0275","series-title":"Compr Physiol","first-page":"1463","article-title":"Oxygen transport by hemoglobin","author":"Mairb\u00e4url","year":"2012"},{"key":"10.1016\/j.bbadis.2025.167767_bb0280","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.5665\/sleep.4814","article-title":"Increased carbonic anhydrase activity is associated with sleep apnea severity and related hypoxemia","volume":"38","author":"Wang","year":"2015","journal-title":"Sleep"},{"key":"10.1016\/j.bbadis.2025.167767_bb0285","doi-asserted-by":"crossref","DOI":"10.1111\/jsr.12956","article-title":"Carbonic anhydrase, obstructive sleep apnea and hypertension: effects of intervention","volume":"29","author":"Hoff","year":"2020","journal-title":"J. Sleep Res."},{"key":"10.1016\/j.bbadis.2025.167767_bb0290","doi-asserted-by":"crossref","DOI":"10.4067\/S0716-97602000000300006","article-title":"Carbonic anhydrase activity in the red blood cells of sea level and high altitude natives","volume":"33","author":"Gamboa","year":"2000","journal-title":"Biol. Res."},{"key":"10.1016\/j.bbadis.2025.167767_bb0295","doi-asserted-by":"crossref","first-page":"2485","DOI":"10.1002\/med.21713","article-title":"Progress in the development of human carbonic anhydrase inhibitors and their pharmacological applications: where are we today?","volume":"40","author":"Mishra","year":"2020","journal-title":"Med. Res. Rev."},{"key":"10.1016\/j.bbadis.2025.167767_bb0300","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/s41392-023-01496-3","article-title":"Pathophysiological mechanisms and therapeutic approaches in obstructive sleep apnea syndrome","volume":"8","author":"Lv","year":"2023","journal-title":"Sig. Transduct. Target. Ther."},{"key":"10.1016\/j.bbadis.2025.167767_bb0305","doi-asserted-by":"crossref","first-page":"3764","DOI":"10.3390\/cancers12123764","article-title":"Ubiquitination and ubiquitin-like modifications in multiple myeloma: biology and therapy","volume":"12","author":"Wirth","year":"2020","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.bbadis.2025.167767_bb0310","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2022.890121","article-title":"Association between neddylation and immune response","volume":"10","author":"Zhu","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0315","series-title":"A Mass Spectrometry-Based Strategy for Mapping Modification Sites for the Ubiquitin-Like Modifier NEDD8","first-page":"137","author":"Oliveira","year":"2023"},{"key":"10.1016\/j.bbadis.2025.167767_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108635","article-title":"Proteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation","volume":"34","author":"Lobato-Gil","year":"2021","journal-title":"Cell Rep."},{"key":"10.1016\/j.bbadis.2025.167767_bb0325","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/s12943-020-01262-x","article-title":"The role of ubiquitination and deubiquitination in cancer metabolism","volume":"19","author":"Sun","year":"2020","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bbadis.2025.167767_bb0330","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1146\/annurev.biochem.67.1.425","article-title":"The ubiquitin system","volume":"67","author":"Hershko","year":"1998","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbadis.2025.167767_bb0335","doi-asserted-by":"crossref","first-page":"32","DOI":"10.3390\/biomedicines8020032","article-title":"Basic biology of hypoxic responses mediated by the transcription factor HIFs and its implication for medicine","volume":"8","author":"Hirota","year":"2020","journal-title":"Biomedicines"},{"key":"10.1016\/j.bbadis.2025.167767_bb0340","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.mam.2016.05.001","article-title":"Degradation of oxidized proteins by the proteasome: distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways","volume":"50","author":"Raynes","year":"2016","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0345","doi-asserted-by":"crossref","first-page":"862","DOI":"10.3390\/biom4030862","article-title":"Regulating the 20S proteasome ubiquitin-independent degradation pathway","volume":"4","author":"Ben-Nissan","year":"2014","journal-title":"Biomolecules"},{"key":"10.1016\/j.bbadis.2025.167767_bb0350","doi-asserted-by":"crossref","first-page":"3622","DOI":"10.1167\/iovs.07-1559","article-title":"The proteasome: a target of oxidative damage in cultured human retina pigment epithelial cells","volume":"49","author":"Zhang","year":"2008","journal-title":"Investigative Opthalmology & Visual Science"},{"key":"10.1016\/j.bbadis.2025.167767_bb0355","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3109\/10409238.2016.1172554","article-title":"The immunoproteasome in oxidative stress, aging, and disease","volume":"51","author":"Johnston-Carey","year":"2016","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.bbadis.2025.167767_bb0360","series-title":"Macromolecular Protein Complexes III: Structure and Function. Subcellular Biochemistry","first-page":"1","article-title":"Structure, dynamics and function of the 26S proteasome","author":"Mao","year":"2021"},{"key":"10.1016\/j.bbadis.2025.167767_bb0365","doi-asserted-by":"crossref","first-page":"6173","DOI":"10.1038\/s41467-021-26427-0","article-title":"The 20S as a stand-alone proteasome in cells can degrade the ubiquitin tag","volume":"12","author":"Sahu","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2025.167767_bb0370","doi-asserted-by":"crossref","first-page":"6963","DOI":"10.1074\/jbc.M110.188706","article-title":"Hypoxia-inducible factor \u03b1 subunit stabilization by NEDD8 conjugation is reactive oxygen species-dependent","volume":"286","author":"Ryu","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.167767_bb0375","doi-asserted-by":"crossref","first-page":"263","DOI":"10.5664\/jcsm.26794","article-title":"Mild obstructive sleep apnea syndrome should not be treated","volume":"3","author":"Littner","year":"2007","journal-title":"J. Clin. Sleep Med."},{"key":"10.1016\/j.bbadis.2025.167767_bb0380","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2024.105052","article-title":"May continuous positive airway pressure (CPAP) treatment be detrimental in obstructive sleep apnea?","volume":"101","author":"Castrogiovanni","year":"2024","journal-title":"EBioMedicine"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925001127?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925001127?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T12:32:50Z","timestamp":1749558770000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443925001127"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":76,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025,6]]}},"alternative-id":["S0925443925001127"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.167767","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Red blood cell proteomic profiling in mild and severe obstructive sleep apnea patients before and after positive airway pressure treatment","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.167767","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167767"}}