{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T19:26:53Z","timestamp":1792092413343,"version":"4.4.0"},"reference-count":54,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,27]],"date-time":"2025-07-27T00:00:00Z","timestamp":1753574400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100013262","name":"State Key Laboratory of Respiratory Disease","doi-asserted-by":"publisher","award":["SKLRD-OP-202320"],"award-info":[{"award-number":["SKLRD-OP-202320"]}],"id":[{"id":"10.13039\/100013262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013262","name":"State Key Laboratory of Respiratory Disease","doi-asserted-by":"publisher","award":["SKLRD-Z-202416"],"award-info":[{"award-number":["SKLRD-Z-202416"]}],"id":[{"id":"10.13039\/100013262","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022973","name":"Guangzhou Institute of Respiratory Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022973","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82270077"],"award-info":[{"award-number":["82270077"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470065"],"award-info":[{"award-number":["82470065"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bbadis.2025.167992","type":"journal-article","created":{"date-parts":[[2025,7,23]],"date-time":"2025-07-23T06:49:13Z","timestamp":1753253353000},"page":"167992","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Impaired ciliogenesis in small airway epithelial cells involves in the development of idiopathic pulmonary fibrosis"],"prefix":"10.1016","volume":"1871","author":[{"given":"Zhaoni","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangsheng","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianxing","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nanshan","family":"Zhong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3383-0989","authenticated-orcid":false,"given":"Xiao Xiao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2025.167992_bb0005","article-title":"New perspectives on the aberrant alveolar repair of idiopathic pulmonary fibrosis","volume":"8","author":"Wang","year":"2020","journal-title":"Frontiers in Cell and Developmental Biology."},{"issue":"10","key":"10.1016\/j.bbadis.2025.167992_bb0010","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1097\/01.LAB.0000032380.82232.67","article-title":"Abnormal re-epithelialization and lung remodeling in idiopathic pulmonary fibrosis: the role of deltaN-p63","volume":"82","author":"Chilosi","year":"2002","journal-title":"Lab. Investig."},{"issue":"4","key":"10.1016\/j.bbadis.2025.167992_bb0015","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1152\/physrev.00004.2016","article-title":"Idiopathic pulmonary fibrosis: a genetic disease that involves mucociliary dysfunction of the peripheral airways","volume":"96","author":"Evans","year":"2016","journal-title":"Physiol. Rev."},{"issue":"6","key":"10.1016\/j.bbadis.2025.167992_bb0020","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S2213-2600(19)30356-X","article-title":"Small airways pathology in idiopathic pulmonary fibrosis: a retrospective cohort study","volume":"8","author":"Verleden","year":"2020","journal-title":"Lancet Respir. Med."},{"key":"10.1016\/j.bbadis.2025.167992_bb0025","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1164\/rccm.202103-0585OC","article-title":"Small airway reduction and fibrosis is an early pathologic feature of idiopathic pulmonary fibrosis","volume":"204","author":"Ikezoe","year":"2021","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0030","doi-asserted-by":"crossref","first-page":"4566","DOI":"10.1038\/s41467-021-24853-8","article-title":"Pulmonary fibrosis distal airway epithelia are dynamically and structurally dysfunctional","volume":"12","author":"Stancil","year":"2021","journal-title":"Nat. Commun."},{"issue":"654","key":"10.1016\/j.bbadis.2025.167992_bb0035","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abo5254","article-title":"Interleukin-6-dependent epithelial fluidization initiates fibrotic lung remodeling","volume":"14","author":"Stancil","year":"2022","journal-title":"Sci. Transl. Med."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0040","doi-asserted-by":"crossref","first-page":"5637","DOI":"10.1038\/s41467-022-33193-0","article-title":"Airway basal cells show a dedifferentiated KRT17high phenotype and promote fibrosis in idiopathic pulmonary fibrosis","volume":"13","author":"Jaeger","year":"2022","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2025.167992_bb0045","doi-asserted-by":"crossref","first-page":"1576","DOI":"10.1056\/NEJMc1013504","article-title":"A variant in the promoter of MUC5B and idiopathic pulmonary fibrosis","volume":"364","author":"Zhang","year":"2011","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.bbadis.2025.167992_bb0050","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1136\/thoraxjnl-2012-201786","article-title":"Mucin 5B promoter polymorphism is associated with idiopathic pulmonary fibrosis but not with development of lung fibrosis in systemic sclerosis or sarcoidosis","volume":"68","author":"Stock","year":"2013","journal-title":"Thorax"},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0055","doi-asserted-by":"crossref","first-page":"5363","DOI":"10.1038\/s41467-018-07768-9","article-title":"Muc5b overexpression causes mucociliary dysfunction and enhances lung fibrosis in mice","volume":"9","author":"Hancock","year":"2018","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.14336\/AD.2021.0730","article-title":"Irreversibility of pulmonary fibrosis","volume":"13","author":"Yu","year":"2022","journal-title":"Aging Dis."},{"issue":"5","key":"10.1016\/j.bbadis.2025.167992_bb0065","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1034\/j.1399-3003.1999.13e39.x","article-title":"Regulation of mucociliary clearance in health and disease","volume":"13","author":"Houtmeyers","year":"1999","journal-title":"Eur. Respir. J."},{"key":"10.1016\/j.bbadis.2025.167992_bb0070","article-title":"Abnormal airway mucus secretion induced by virus infection","volume":"12","author":"Li","year":"2021","journal-title":"Front. Immunol."},{"issue":"58","key":"10.1016\/j.bbadis.2025.167992_bb0075","doi-asserted-by":"crossref","first-page":"3503","DOI":"10.1183\/13993003\/erj.44.Suppl_58.P3503","article-title":"Mucus production, lung inflammation and functional decay in IPF","volume":"44","author":"Turato","year":"2014","journal-title":"Eur. Respir. J."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0080","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1165\/rcmb.2022-0252OC","article-title":"Epithelial endoplasmic reticulum stress enhances the risk of muc5b-associated lung fibrosis","volume":"68","author":"Dobrinskikh","year":"2023","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbadis.2025.167992_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.810842","article-title":"Mucus hypersecretion and ciliary impairment in conducting airway contribute to alveolar mucus plugging in idiopathic pulmonary fibrosis","volume":"9","author":"Peng","year":"2022","journal-title":"Front. Cell Dev. Biol."},{"issue":"12","key":"10.1016\/j.bbadis.2025.167992_bb0090","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1136\/thoraxjnl-2012-202943","article-title":"Expression of cilium-associated genes defines novel molecular subtypes of idiopathic pulmonary fibrosis","volume":"68","author":"Yang","year":"2013","journal-title":"Thorax"},{"issue":"2","key":"10.1016\/j.bbadis.2025.167992_bb0095","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1165\/rcmb.2021-0554OC","article-title":"Aberrant multiciliogenesis in idiopathic pulmonary fibrosis","volume":"67","author":"Kim","year":"2022","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"issue":"22","key":"10.1016\/j.bbadis.2025.167992_bb0100","doi-asserted-by":"crossref","first-page":"2093","DOI":"10.1056\/NEJMoa1401739","article-title":"Randomized trial of acetylcysteine in idiopathic pulmonary fibrosis","volume":"370","author":"Idiopathic Pulmonary Fibrosis Clinical Research Network","year":"2014","journal-title":"N. Engl. J. Med."},{"issue":"5","key":"10.1016\/j.bbadis.2025.167992_bb0105","doi-asserted-by":"crossref","first-page":"e44","DOI":"10.1164\/rccm.201807-1255ST","article-title":"Diagnosis of idiopathic pulmonary fibrosis. An official ATS\/ERS\/JRS\/ALAT clinical practice guideline","volume":"198","author":"Raghu","year":"2018","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0110","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1038\/s41392-023-01511-7","article-title":"Dicoumarol is an effective post-exposure prophylactic for SARS-CoV-2 Omicron infection in human airway epithelium","volume":"8","author":"Peng","year":"2023","journal-title":"Signal Transduct. Target. Ther."},{"issue":"12","key":"10.1016\/j.bbadis.2025.167992_bb0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2021.166204","article-title":"Iron deposition-induced ferroptosis in alveolar type II cells promotes the development of pulmonary fibrosis","volume":"1867","author":"Cheng","year":"2021","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0120","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/S1383-5718(99)00080-7","article-title":"Enhancement of bleomycin-induced micronucleus formation in V79 cells as a rapid and sensitive screen for non-covalent DNA-binding compounds","volume":"444","author":"Snyder","year":"1999","journal-title":"Mutat. Res."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0125","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1038\/s41392-024-02011-y","article-title":"Overexpression of STX11 alleviates pulmonary fibrosis by inhibiting fibroblast activation via the PI3K\/AKT\/mTOR pathway","volume":"9","author":"Huang","year":"2024","journal-title":"Signal Transduct. Target. Ther."},{"issue":"5","key":"10.1016\/j.bbadis.2025.167992_bb0130","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.867","article-title":"Induction of connective tissue growth factor accounts for the inability of glucocorticoid suppression on pulmonary fibrosis","volume":"12","author":"Wang","year":"2022","journal-title":"Clin. Transl. Med."},{"issue":"4","key":"10.1016\/j.bbadis.2025.167992_bb0135","doi-asserted-by":"crossref","first-page":"507","DOI":"10.2144\/000112729","article-title":"Standardized quantification of pulmonary fibrosis in histological samples","volume":"44","author":"H\u00fcbner","year":"2008","journal-title":"Biotechniques"},{"issue":"10082","key":"10.1016\/j.bbadis.2025.167992_bb0140","doi-asserted-by":"crossref","first-page":"1941","DOI":"10.1016\/S0140-6736(17)30866-8","article-title":"Idiopathic pulmonary fibrosis","volume":"389","author":"Richeldi","year":"2017","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.bbadis.2025.167992_bb0145","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/j.pccm.2024.04.001","article-title":"Cell\u2013cell interactions and communication dynamics in lung fibrosis","volume":"2","author":"Xie","year":"2024","journal-title":"Chin Med J Pulm Crit Care Med."},{"issue":"2","key":"10.1016\/j.bbadis.2025.167992_bb0150","first-page":"L152","article-title":"Murine models of pulmonary fibrosis","volume":"294","author":"Moore","year":"2008","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"issue":"6","key":"10.1016\/j.bbadis.2025.167992_bb0155","first-page":"L771","article-title":"Notch signaling inactivation by small molecule \u03b3-secretase inhibitors restores the multiciliated cell population in the airway epithelium","volume":"324","author":"Vladar","year":"2023","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0160","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1038\/s41467-023-36743-2","article-title":"Mucociliary Wnt signaling promotes cilia biogenesis and beating","volume":"14","author":"Seidl","year":"2023","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0165","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.ajpath.2011.03.016","article-title":"\u03b2-Catenin dosage is a critical determinant of tracheal basal cell fate determination","volume":"179","author":"Brechbuhl","year":"2011","journal-title":"Am. J. Pathol."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0170","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1093\/molbev\/mst176","article-title":"Hedgehog signaling requires motile cilia in the sea urchin","volume":"31","author":"Warner","year":"2014","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.bbadis.2025.167992_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2019.11.033","article-title":"Airway epithelial cell differentiation relies on deficient Hedgehog signalling in COPD","volume":"51","author":"Belgacemi","year":"2020","journal-title":"EBioMedicine"},{"issue":"3","key":"10.1016\/j.bbadis.2025.167992_bb0180","doi-asserted-by":"crossref","first-page":"400","DOI":"10.15252\/embr.201540882","article-title":"GemC1 controls multiciliogenesis in the airway epithelium","volume":"17","author":"Arbi","year":"2016","journal-title":"EMBO Rep."},{"issue":"7","key":"10.1016\/j.bbadis.2025.167992_bb0185","doi-asserted-by":"crossref","first-page":"1318","DOI":"10.1016\/j.ajhg.2021.05.002","article-title":"Mutations in TP73 cause impaired mucociliary clearance and lissencephaly","volume":"108","author":"Wallmeier","year":"2021","journal-title":"Am. J. Hum. Genet."},{"issue":"20","key":"10.1016\/j.bbadis.2025.167992_bb0190","doi-asserted-by":"crossref","first-page":"4277","DOI":"10.1242\/dev.094102","article-title":"Myb promotes centriole amplification and later steps of the multiciliogenesis program","volume":"140","author":"Tan","year":"2013","journal-title":"Development"},{"issue":"8","key":"10.1016\/j.bbadis.2025.167992_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.jbc.2023.104964","article-title":"Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63","volume":"299","author":"Li","year":"2023","journal-title":"J. Biol. Chem."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0200","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.ydbio.2006.02.038","article-title":"Sox17 influences the differentiation of respiratory epithelial cells","volume":"294","author":"Park","year":"2006","journal-title":"Dev. Biol."},{"issue":"5","key":"10.1016\/j.bbadis.2025.167992_bb0205","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/S0002-9440(10)64271-X","article-title":"Wnt signaling and pulmonary fibrosis","volume":"162","author":"Morrisey","year":"2003","journal-title":"Am. J. Pathol."},{"issue":"11","key":"10.1016\/j.bbadis.2025.167992_bb0210","first-page":"L978","article-title":"Role of Sonic Hedgehog in idiopathic pulmonary fibrosis","volume":"303","author":"Bola\u00f1os","year":"2012","journal-title":"Am. J. Phys. Lung Cell. Mol. Phys."},{"issue":"1","key":"10.1016\/j.bbadis.2025.167992_bb0215","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/cdd.2017.178","article-title":"Non-oncogenic roles of TAp73: from multiciliogenesis to metabolism","volume":"25","author":"Nemajerova","year":"2018","journal-title":"Cell Death Differ."},{"issue":"8","key":"10.1016\/j.bbadis.2025.167992_bb0220","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1089\/omi.2023.0072","article-title":"Idiopathic pulmonary fibrosis molecular substrates revealed by competing endogenous RNA regulatory networks","volume":"27","author":"Kircali","year":"2023","journal-title":"OMICS"},{"issue":"17","key":"10.1016\/j.bbadis.2025.167992_bb0225","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.122490","article-title":"MEG3 is increased in idiopathic pulmonary fibrosis and regulates epithelial cell differentiation","volume":"3","author":"Gokey","year":"2018","journal-title":"JCI Insight"},{"key":"10.1016\/j.bbadis.2025.167992_bb0230","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.rmed.2018.12.015","article-title":"Inflammation and immunity in IPF pathogenesis and treatment","volume":"147","author":"Heukels","year":"2019","journal-title":"Respir. Med."},{"issue":"3","key":"10.1016\/j.bbadis.2025.167992_bb0235","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1016\/j.virs.2022.04.008","article-title":"FoxJ1 inhibits African swine fever virus replication and viral S273R protein decreases the expression of FoxJ1 to impair its antiviral effect","volume":"37","author":"Ma","year":"2022","journal-title":"Virol. Sin."},{"key":"10.1016\/j.bbadis.2025.167992_bb0240","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms14532","article-title":"Cellular senescence mediates fibrotic pulmonary disease","volume":"8","author":"Schafer","year":"2017","journal-title":"Nat. Commun."},{"issue":"6","key":"10.1016\/j.bbadis.2025.167992_bb0245","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1164\/rccm.202004-1274OC","article-title":"Senescence of alveolar type 2 cells drives progressive pulmonary fibrosis","volume":"203","author":"Yao","year":"2021","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"3","key":"10.1016\/j.bbadis.2025.167992_bb0250","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1164\/rccm.201210-1843CI","article-title":"Chronic bronchitis and chronic obstructive pulmonary disease","volume":"187","author":"Kim","year":"2013","journal-title":"Am. J. Respir. Crit. Care Med."},{"issue":"2","key":"10.1016\/j.bbadis.2025.167992_bb0255","doi-asserted-by":"crossref","DOI":"10.1183\/13993003.01699-2018","article-title":"Idiopathic pulmonary fibrosis: unmasking cryptogenic environmental factors","volume":"53","author":"Sack","year":"2019","journal-title":"Eur. Respir. J."},{"issue":"6097","key":"10.1016\/j.bbadis.2025.167992_bb0260","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1126\/science.1223012","article-title":"A periciliary brush promotes the lung health by separating the mucus layer from airway epithelia","volume":"337","author":"Button","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbadis.2025.167992_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2025.108360","article-title":"Discovery of novel selective HDAC6 inhibitors via a scaffold hopping approach for the treatment of idiopathic pulmonary fibrosis (IPF) in vitro and in vivo","volume":"159","author":"Quan","year":"2025","journal-title":"Bioorg. Chem."},{"issue":"7","key":"10.1016\/j.bbadis.2025.167992_bb0270","doi-asserted-by":"crossref","first-page":"2259","DOI":"10.1158\/0008-5472.CAN-12-2938","article-title":"Hdac6 inhibition restores ciliary expression and decreases tumor growth","volume":"73","author":"Gradilone","year":"2013","journal-title":"Cancer Res."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925003400?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925003400?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:10:03Z","timestamp":1778551803000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443925003400"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":54,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,11]]}},"alternative-id":["S0925443925003400"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.167992","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Impaired ciliogenesis in small airway epithelial cells involves in the development of idiopathic pulmonary fibrosis","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.167992","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"167992"}}