{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:25:41Z","timestamp":1786735541394,"version":"build-2736575974"},"reference-count":277,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100020884","name":"National Agency for Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020884","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002850","name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["1200178"],"award-info":[{"award-number":["1200178"]}],"id":[{"id":"10.13039\/501100002850","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.bbadis.2025.168059","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T07:57:07Z","timestamp":1758614227000},"page":"168059","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Is tau pathology a relevant factor in neuronal damage induced by alcohol and other drugs?"],"prefix":"10.1016","volume":"1872","author":[{"given":"Margrethe A.","family":"Olesen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s","family":"Anc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo A.","family":"Quintanilla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2025.168059_bb0005","article-title":"It\u2019s all about tau","volume":"175","author":"Tapia-Rojas","year":"2018","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0010","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-023-03434-4","article-title":"Pathological impact of tau proteolytical process on neuronal and mitochondrial function: a crucial role in Alzheimer\u2019s disease","volume":"60","author":"Olesen","year":"2023","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0015","doi-asserted-by":"crossref","DOI":"10.1177\/37.2.2492045","article-title":"Distribution of tau proteins in the normal human central and peripheral nervous system","volume":"37","author":"Trojanowski","year":"1989","journal-title":"J. Histochem. Cytochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.parkreldis.2015.09.020","article-title":"Tauopathies as clinicopathological entities","volume":"22","author":"Irwin","year":"2016","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.bbadis.2025.168059_bb0025","doi-asserted-by":"crossref","DOI":"10.3389\/fneur.2020.590059","article-title":"Much more than a cytoskeletal protein: physiological and pathological functions of the non-microtubule binding region of tau","volume":"11","author":"Brandt","year":"2020","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.tcb.2019.02.007","article-title":"Tau: it\u2019s not what you think","volume":"29","author":"Baas","year":"2019","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/S0021-9258(17)42989-9","article-title":"Phosphorylation affects the ability of tau protein to promote microtubule assembly","volume":"259","author":"Lindwall","year":"1984","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0040","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a006437","article-title":"Developing therapeutic approaches to tau, selected kinases, and related neuronal protein targets","volume":"1","author":"Lee","year":"2011","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0045","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M111.309385","article-title":"\u03b3-Aminobutyric acid type A (GABA A) receptor activation modulates Tau phosphorylation","volume":"287","author":"Nyk\u00e4nen","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0050","article-title":"Abnormal hyperphosphorylation of tau: sites, regulation, and molecular mechanism of neurofibrillary degeneration","volume":"33","author":"Wang","year":"2013","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0055","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M511697200","article-title":"Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation","volume":"281","author":"Ding","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0060","doi-asserted-by":"crossref","DOI":"10.1172\/JCI200420640","article-title":"Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology","volume":"114","author":"Rissman","year":"2004","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2025.168059_bb0065","doi-asserted-by":"crossref","DOI":"10.1007\/s11064-016-1942-9","article-title":"Caspase-3-dependent proteolytic cleavage of tau causes neurofibrillary tangles and results in cognitive impairment during normal aging","volume":"41","author":"Means","year":"2016","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0070","doi-asserted-by":"crossref","DOI":"10.1007\/s00702-004-0221-0","article-title":"Post-translational modifications of tau protein in Alzheimer\u2019s disease","volume":"112","author":"Gong","year":"2005","journal-title":"J. Neural Transm."},{"key":"10.1016\/j.bbadis.2025.168059_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166898","article-title":"Caspase-3 cleaved tau impairs mitochondrial function through the opening of the mitochondrial permeability transition pore","volume":"1870","author":"P\u00e9rez","year":"2024","journal-title":"Biochim. Biophys. Acta Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2015.12.006","article-title":"Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model","volume":"87","author":"Kim","year":"2016","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.freeradbiomed.2025.02.035","article-title":"Cyclophilin D (CypD) ablation prevents neurodegenerative and cognitive damage induced by caspase-3 cleaved tau","author":"Olesen","year":"2025","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0090","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-017-0385-x","article-title":"Caspase-cleaved tau impairs mitochondrial dynamics in Alzheimer\u2019s disease","volume":"55","author":"P\u00e9rez","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0095","article-title":"Mechanism of psychoactive substance-induced cognitive disorders: does tau protein play a role?","volume":"27","author":"YuYe Wnag","year":"2022","journal-title":"Front. Biosci. Landmark"},{"key":"10.1016\/j.bbadis.2025.168059_bb0100","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.121119298","article-title":"Hyperphosphorylation induces self-assembly of \u03c4 into tangles of paired helical filaments\/straight filaments","volume":"98","author":"Alonso","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0105","doi-asserted-by":"crossref","DOI":"10.1186\/s40478-022-01457-x","article-title":"Artificial intelligence-derived neurofibrillary tangle burden is associated with antemortem cognitive impairment","volume":"10","author":"Marx","year":"2022","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb0110","doi-asserted-by":"crossref","DOI":"10.1007\/s12031-020-01613-9","article-title":"Effects of single-dose and long-term ketamine administration on tau phosphorylation\u2013related enzymes GSK-3\u03b2, CDK5, PP2A, and PP2B in the mouse Hippocampus","volume":"70","author":"Li","year":"2020","journal-title":"J. Mol. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0115","doi-asserted-by":"crossref","DOI":"10.1096\/fj.201902135R","article-title":"Tau hyperphosphorylation induced by the anesthetic agent ketamine\/xylazine involved the calmodulin-dependent protein kinase II","volume":"34","author":"Hector","year":"2020","journal-title":"FASEB J."},{"key":"10.1016\/j.bbadis.2025.168059_bb0120","doi-asserted-by":"crossref","DOI":"10.1001\/jamanetworkopen.2019.10319","article-title":"Alcohol consumption and risk of dementia and cognitive decline among older adults with or without mild cognitive impairment","volume":"2","author":"Koch","year":"2019","journal-title":"JAMA Netw. Open"},{"key":"10.1016\/j.bbadis.2025.168059_bb0125","article-title":"Alcohol consumption and risk of dementia: 23 year follow-up of Whitehall II cohort study","volume":"362","author":"Sabia","year":"2018","journal-title":"BMJ (Online)"},{"key":"10.1016\/j.bbadis.2025.168059_bb0130","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21072316","article-title":"Role of alcohol drinking in Alzheimer\u2019s disease, Parkinson\u2019s disease, and amyotrophic lateral sclerosis","volume":"21","author":"Peng","year":"2020","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0135","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26157638","article-title":"Substance abuse and cognitive decline: the critical role of tau protein as a potential biomarker","volume":"26","author":"Rebolledo-P\u00e9rez","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0140","doi-asserted-by":"crossref","DOI":"10.3390\/biology12050752","article-title":"Cocaine destroys gray matter brain cells and accelerates brain aging","volume":"12","author":"Beheshti","year":"2023","journal-title":"Biology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0145","doi-asserted-by":"crossref","first-page":"1729","DOI":"10.1038\/s41386-024-01882-7","article-title":"Cognitive performance as a behavioral phenotype associated with cocaine self-administration in female and male socially housed monkeys","volume":"49","author":"Allen","year":"2024","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0150","doi-asserted-by":"crossref","DOI":"10.1186\/s12883-019-1496-y","article-title":"Dynamic interaction of genetic risk factors and cocaine abuse in the background of Parkinsonism - a case report","volume":"19","author":"Ill\u00e9s","year":"2019","journal-title":"BMC Neurol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0155","article-title":"Impact of prescribed opioid use on development of dementia among patients with chronic non-cancer pain","volume":"14","author":"Oh","year":"2024","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2025.168059_bb0160","doi-asserted-by":"crossref","DOI":"10.1111\/acer.13211","article-title":"Current heavy alcohol consumption is associated with greater cognitive impairment in older adults","volume":"40","author":"Woods","year":"2016","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0165","doi-asserted-by":"crossref","DOI":"10.1126\/scisignal.aba5754","article-title":"Daily alcohol intake triggers aberrant synaptic pruning leading to synapse loss and anxiety-like behavior","volume":"13","author":"Socodato","year":"2020","journal-title":"Sci. Signal."},{"key":"10.1016\/j.bbadis.2025.168059_bb0170","doi-asserted-by":"crossref","DOI":"10.1007\/s00210-018-1475-7","article-title":"Microglial IL-1\u03b2 progressively increases with duration of alcohol consumption","volume":"391","author":"Pradier","year":"2018","journal-title":"Naunyn Schmiedeberg's Arch. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2006.06.012","article-title":"Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells","volume":"50","author":"Poon","year":"2007","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bbadis.2025.168059_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2008.07.052","article-title":"Ethanol enhances tau accumulation in neuroblastoma cells that inducibly express tau","volume":"443","author":"Gendron","year":"2008","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb0185","article-title":"Ketamine induces tau hyperphosphorylation at serine 404 in the hippocampus of neonatal rats","volume":"8","author":"Jin","year":"2013","journal-title":"Neural Regen. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0190","article-title":"Alzheimer-like phosphorylation of tau and neurofilament induced by cocaine in vivo","volume":"24","author":"Liu","year":"2003","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.bbadis.2025.168059_bb0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurobiolaging.2015.07.018","article-title":"Heroin abuse exaggerates age-related deposition of hyperphosphorylated tau and p62-positive inclusions","volume":"36","author":"Kovacs","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbadis.2025.168059_bb0200","doi-asserted-by":"crossref","DOI":"10.1111\/j.1365-2990.2005.00670.x","article-title":"Hyperphosphorylated tau and amyloid precursor protein deposition is increased in the brains of young drug abusers","volume":"31","author":"Ramage","year":"2005","journal-title":"Neuropathol. Appl. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2013.08.001","article-title":"Ethanol impairs microtubule formation via interactions at a microtubule associated protein-sensitive site","volume":"47","author":"Smith","year":"2013","journal-title":"Alcohol"},{"key":"10.1016\/j.bbadis.2025.168059_bb0210","doi-asserted-by":"crossref","DOI":"10.3390\/brainsci8090175","article-title":"The loss of \u03b1-and \u03b2-tubulin proteins are a pathological hallmark of chronic alcohol consumption and natural brain ageing","volume":"8","author":"Labisso","year":"2018","journal-title":"Brain Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2022.08.008","article-title":"Tauopathy and alcohol consumption interact to alter locus coeruleus excitatory transmission and excitability in male and female mice","volume":"107","author":"Downs","year":"2023","journal-title":"Alcohol"},{"key":"10.1016\/j.bbadis.2025.168059_bb0220","doi-asserted-by":"crossref","DOI":"10.3390\/ijms25063301","article-title":"TBI and tau loss of function both affect na\u00efve ethanol sensitivity in Drosophila","volume":"25","author":"Hoxha","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/bs.irn.2019.10.017","article-title":"Alcohol drinking exacerbates neural and behavioral pathology in the 3xTg-AD mouse model of Alzheimer\u2019s disease","author":"Hoffman","year":"2019","journal-title":"Int. Rev. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0230","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.884170","article-title":"Adolescent binge alcohol enhances early Alzheimer\u2019s disease pathology in adulthood through proinflammatory neuroimmune activation","volume":"13","author":"Barnett","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0235","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.1999.tb04156.x","article-title":"Cerebrospinal fluid tau protein levels in demented and nondemented alcoholics","volume":"23","author":"Morikawa","year":"1999","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0240","doi-asserted-by":"crossref","DOI":"10.1111\/adb.13232","article-title":"Plasma tau, NfL, GFAP and UCHL1 as candidate biomarkers of alcohol withdrawal-associated brain damage: a pilot study","volume":"27","author":"Clergue-Duval","year":"2022","journal-title":"Addict. Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0245","doi-asserted-by":"crossref","DOI":"10.3233\/JAD-210140","article-title":"Associations of alcohol consumption with cerebrospinal fluid biomarkers of Alzheimer\u2019s disease pathology in cognitively intact older adults: the CABLE study","volume":"82","author":"Wang","year":"2021","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0250","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.72.5.1858","article-title":"A protein factor essential for microtubule assembly","volume":"72","author":"Weingarten","year":"1975","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0255","doi-asserted-by":"crossref","DOI":"10.1002\/cm.21796","article-title":"The discovery of tau protein","volume":"81","author":"Kirschner","year":"2024","journal-title":"Cytoskeleton"},{"key":"10.1016\/j.bbadis.2025.168059_bb0260","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.101.4.1371","article-title":"The distribution central nervous of tau in system the mammalian","volume":"101","author":"Binder","year":"1985","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0265","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2021.105273","article-title":"Tau associated peripheral and central neurodegeneration: identification of an early imaging marker for tauopathy","volume":"151","author":"Marquez","year":"2021","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0270","doi-asserted-by":"crossref","DOI":"10.1091\/mbc.3.10.1141","article-title":"Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau","volume":"3","author":"Drechsel","year":"1992","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbadis.2025.168059_bb0275","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M110.105387","article-title":"Tau potentiates nerve growth factor-induced mitogen-activated protein kinase signaling and neurite initiation without a requirement for microtubule binding","volume":"285","author":"Leugers","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0280","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.4674-06.2007","article-title":"Missorting of tau in neurons causes degeneration of synapses that can be rescued by the kinase MARK2\/Par-1","volume":"27","author":"Thies","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0285","doi-asserted-by":"crossref","DOI":"10.1038\/emboj.2011.376","article-title":"Novel diffusion barrier for axonal retention of tau in neurons and its failure in neurodegeneration","volume":"30","author":"Li","year":"2011","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2025.168059_bb0290","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.0927-07.2007","article-title":"Swimming against the tide: mobility of the microtubule-associated protein tau in neurons","volume":"27","author":"Konzack","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0295","doi-asserted-by":"crossref","DOI":"10.1016\/0896-6273(89)90210-9","article-title":"Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer\u2019s disease","volume":"3","author":"Goedert","year":"1989","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2025.168059_bb0300","doi-asserted-by":"crossref","DOI":"10.1016\/S0165-0173(00)00019-9","article-title":"Tau protein isoforms, phosphorylation and role in neurodegenerative disorders","volume":"33","author":"Bu\u00e9e","year":"2000","journal-title":"Brain Res. Rev."},{"key":"10.1016\/j.bbadis.2025.168059_bb0305","doi-asserted-by":"crossref","DOI":"10.1146\/annurev-pathmechdis-012418-012936","article-title":"Molecular pathogenesis of the tauopathies","volume":"14","author":"G\u00f6tz","year":"2019","journal-title":"Annu. Rev. Pathol.: Mech. Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0310","doi-asserted-by":"crossref","DOI":"10.1021\/bi00158a027","article-title":"Structure and novel exons of the human \u03c4 gene","volume":"31","author":"Andreadis","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0315","doi-asserted-by":"crossref","first-page":"3606","DOI":"10.1002\/alz.13784","article-title":"The six brain-specific TAU isoforms and their role in Alzheimer\u2019s disease and related neurodegenerative dementia syndromes","volume":"20","author":"Buchholz","year":"2024","journal-title":"Alzheimers Dement."},{"key":"10.1016\/j.bbadis.2025.168059_bb0320","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajpath.2013.03.015","article-title":"Neurodegenerative disorder FTDP-17-related tau intron 10 +16C\u2192T mutation increases tau exon 10 splicing and causes tauopathy in transgenic mice","volume":"183","author":"Umeda","year":"2013","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0325","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0010810","article-title":"Three repeat isoforms of tau inhibit assembly of four repeat tau filaments","volume":"5","author":"Adams","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2025.168059_bb0330","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.5492-06.2007","article-title":"The tau N279K exon 10 splicing mutation recapitulates frontotemporal dementia and Parkinsonism linked to chromosome 17 tauopathy in a mouse model","volume":"27","author":"Dawson","year":"2007","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0335","doi-asserted-by":"crossref","DOI":"10.1021\/bi3010818","article-title":"FTDP-17 tau mutations induce distinct effects on aggregation and microtubule interactions","volume":"51","author":"Combs","year":"2012","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0340","doi-asserted-by":"crossref","DOI":"10.1111\/j.1471-4159.2008.05692.x","article-title":"Pathogenic missense MAPT mutations differentially modulate tau aggregation propensity at nucleation and extension steps","volume":"107","author":"Chang","year":"2008","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0345","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.RA119.010178","article-title":"Impaired tau-microtubule interactions are prevalent among pathogenic tau variants arising from missense mutations","volume":"294","author":"Xia","year":"2019","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0350","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M405131200","article-title":"Promotion of hyperphosphorylation by frontotemporal dementia tau mutations","volume":"279","author":"Alonso","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0355","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.01558","article-title":"Tau phosphorylation in neuronal cell function and dysfunction","volume":"117","author":"Johnson","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0360","doi-asserted-by":"crossref","DOI":"10.1007\/s00401-010-0716-8","article-title":"Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo","volume":"120","author":"Cowan","year":"2010","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0365","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-020-02034-w","article-title":"Hyperphosphorylation renders tau prone to aggregate and to cause cell death","volume":"57","author":"Liu","year":"2020","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0370","doi-asserted-by":"crossref","DOI":"10.1186\/1750-1326-2-12","article-title":"Tau phosphorylation by GSK-3\u00df promotes tangle-like filament morphology","volume":"2","author":"Rankin","year":"2007","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.bbadis.2025.168059_bb0375","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M107182200","article-title":"Glycogen synthase kinase-3\u03b2 is complexed with tau protein in brain microtubules","volume":"277","author":"Sun","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0380","series-title":"GSK3\u03b2 Phosphorylation Catalyzes the Aggregation of Tau Into Alzheimer's Disease-like Amyloid Strain","author":"Chakraborty","year":"2023"},{"key":"10.1016\/j.bbadis.2025.168059_bb0385","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2006.10.011","article-title":"Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats","volume":"1772","author":"Wen","year":"2007","journal-title":"Biochim. Biophys. Acta Mol. basis Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0390","doi-asserted-by":"crossref","DOI":"10.1038\/sj.emboj.7600441","article-title":"A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons","volume":"24","author":"Zheng","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2025.168059_bb0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.tibs.2003.12.004","article-title":"The glamour and gloom of glycogen synthase kinase-3","volume":"29","author":"Jope","year":"2004","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0400","doi-asserted-by":"crossref","DOI":"10.3390\/cells10040721","article-title":"GSK-3 and tau: a key duet in Alzheimer\u2019s disease","volume":"10","author":"Sayas","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2025.168059_bb0405","doi-asserted-by":"crossref","DOI":"10.1111\/j.1471-4159.2004.02155.x","article-title":"Primed phosphorylation of tau at Thr231 by glycogen synthase kinase 3\u03b2 (GSK3\u03b2) plays a critical role in regulating tau\u2019s ability to bind and stabilize microtubules","volume":"88","author":"Cho","year":"2004","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0410","doi-asserted-by":"crossref","DOI":"10.1093\/emboj\/20.1.27","article-title":"Decreased nuclear \u03b2-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3\u03b2 conditional transgenic mice","volume":"20","author":"Lucas","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.bbadis.2025.168059_bb0415","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2007.10.064","article-title":"Amyloid-beta-induced neurotoxicity is reduced by inhibition of glycogen synthase kinase-3","volume":"1188","author":"Koh","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0420","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-015-9138-x","article-title":"Role of Wnt signaling in central nervous system injury","volume":"53","author":"Lambert","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0425","doi-asserted-by":"crossref","DOI":"10.1046\/j.1471-4159.2002.01269.x","article-title":"Spatial learning deficit in transgenic mice that conditionally over-express GSK-3\u03b2 in the brain but do not form tau filaments","volume":"83","author":"Hern\u00e1ndez","year":"2002","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0430","doi-asserted-by":"crossref","DOI":"10.1038\/mp.2013.4","article-title":"GSK-3\u03b2 overexpression causes reversible alterations on postsynaptic densities and dendritic morphology of hippocampal granule neurons in vivo","volume":"18","author":"Llorens-Mart\u00edn","year":"2013","journal-title":"Mol. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0435","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2008.02.019","article-title":"Involvement of cyclin-dependent kinase 5 in 2,5-hexanedione-induced neuropathy","volume":"248","author":"Wang","year":"2008","journal-title":"Toxicology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0440","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2011.06.020","article-title":"Twice switched at birth: cell cycle-independent roles of the \u201cneuron-specific\u201d cyclin-dependent kinase 5 (Cdk5) in non-neuronal cells","volume":"23","author":"Liebl","year":"2011","journal-title":"Cell. Signal."},{"key":"10.1016\/j.bbadis.2025.168059_bb0445","doi-asserted-by":"crossref","DOI":"10.1016\/S0896-6273(03)00627-5","article-title":"Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles","volume":"40","author":"Cruz","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2025.168059_bb0450","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.0806078105","article-title":"Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology","volume":"105","author":"Meyer","year":"2008","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0455","doi-asserted-by":"crossref","DOI":"10.1016\/j.pneurobio.2020.101906","article-title":"Dual-specificity phosphatases in mental and neurological disorders","volume":"198","author":"An","year":"2021","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0460","article-title":"Dephosphorylation of Alzheimer paired helical filaments by protein phosphatase-2A and -2B","volume":"270","author":"Wang","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0465","doi-asserted-by":"crossref","DOI":"10.1111\/j.1460-9568.2006.05226.x","article-title":"Kinases and phosphatases and tau sites involved in Alzheimer neurofibrillary degeneration","volume":"25","author":"Wang","year":"2007","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0470","article-title":"The carboxy-terminal fragment of inhibitor-2 of protein phosphatase-2A induces Alzheimer disease pathology and cognitive impairment","volume":"24","author":"Wang","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.bbadis.2025.168059_bb0475","doi-asserted-by":"crossref","DOI":"10.1016\/j.etap.2021.103611","article-title":"An update in toxicology of ageing","volume":"84","author":"Rackova","year":"2021","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0480","doi-asserted-by":"crossref","DOI":"10.1038\/35079077","article-title":"Single cocaine exposure in vivo induces long-term potentiation in dopamine neurons","volume":"411","author":"Ungless","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2025.168059_bb0485","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.2002.tb02551.x","article-title":"Effects of combined systemic alcohol and central nicotine administration into ventral tegmental area on dopamine release in the nucleus accumbens","volume":"26","author":"Tizabi","year":"2002","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0490","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainresbull.2016.09.002","article-title":"Specialized roles of neurofilament proteins in synapses: relevance to neuropsychiatric disorders","volume":"126","author":"Yuan","year":"2016","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bbadis.2025.168059_bb0495","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.85.14.5274","article-title":"Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats","volume":"85","author":"Di Chiara","year":"1988","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0500","doi-asserted-by":"crossref","DOI":"10.1111\/ejn.13248","article-title":"Amphetamine elevates nucleus accumbens dopamine via an action potential-dependent mechanism that is modulated by endocannabinoids","volume":"43","author":"Covey","year":"2016","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0505","doi-asserted-by":"crossref","DOI":"10.1002\/syn.10095","article-title":"Repeated ventral tegmental area amphetamine administration alters dopamine D1 receptor signaling in the nucleus accumbens","volume":"45","author":"Hu","year":"2002","journal-title":"Synapse"},{"key":"10.1016\/j.bbadis.2025.168059_bb0510","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2021.794544","article-title":"Alterations in excitatory and inhibitory synaptic development within the mesolimbic dopamine pathway in a mouse model of prenatal drug exposure","volume":"9","author":"Boggess","year":"2021","journal-title":"Front. Pediatr."},{"key":"10.1016\/j.bbadis.2025.168059_bb0515","doi-asserted-by":"crossref","DOI":"10.1016\/S0893-133X(01)00299-8","article-title":"Cocaine and amphetamine depress striatal GABAergic synaptic transmission through D2 dopamine receptors","volume":"26","author":"Centonze","year":"2002","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0520","doi-asserted-by":"crossref","DOI":"10.1093\/cercor\/bhaa331","article-title":"3D synaptic organization of the rat CA1 and alterations induced by cocaine self-administration","volume":"31","author":"Blazquez-Llorca","year":"2021","journal-title":"Cereb. Cortex"},{"key":"10.1016\/j.bbadis.2025.168059_bb0525","doi-asserted-by":"crossref","DOI":"10.1016\/j.phrs.2024.107143","article-title":"IUPHAR-review: targeting the cytoskeleton as a therapeutic approach to substance use disorders","volume":"202","author":"Pandey","year":"2024","journal-title":"Pharmacol. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0530","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.12-06-02165.1992","article-title":"Neurofilament proteins and the mesolimbic dopamine system: common regulation by chronic morphine and chronic cocaine in the rat ventral tegmental area","volume":"12","author":"Beitner-Johnson","year":"1992","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0535","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2003.10.006","article-title":"Neurofilament proteins and cAMP pathway in brains of \u03bc-, \u03b4- or \u03ba-opioid receptor gene knock-out mice: effects of chronic morphine administration","volume":"46","author":"Garc\u00eda-Sevilla","year":"2004","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0540","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.1993.tb00803.x","article-title":"Alcohol-preferring and nonpreferring rats display different levels of neurofilament proteins in the ventral tegmental area","volume":"17","author":"Guitart","year":"1993","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0545","doi-asserted-by":"crossref","DOI":"10.1002\/syn.890210403","article-title":"Biochemical actions of chronic ethanol exposure in the mesolimbic dopamine system","volume":"21","author":"Ortiz","year":"1995","journal-title":"Synapse"},{"key":"10.1016\/j.bbadis.2025.168059_bb0550","doi-asserted-by":"crossref","DOI":"10.1038\/sj.npp.1300095","article-title":"Downregulation of neuronal cdk5\/p35 in opioid addicts and opiate-treated rats: relation to neurofilamentphosphorylation","volume":"28","author":"Ferrer-Alc\u00f3n","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0555","doi-asserted-by":"crossref","DOI":"10.1017\/S1461145706007061","article-title":"Calpain- and caspase-mediated \u03b1II-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure","volume":"10","author":"Warren","year":"2007","journal-title":"Int. J. Neuropsychopharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0560","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1016\/j.freeradbiomed.2024.03.017","article-title":"Mitochondria-tau association promotes cognitive decline and hippocampal bioenergetic deficits during the aging","volume":"217","author":"Olesen","year":"2024","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0565","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.23-06-02488.2003","article-title":"Striatal cell type-specific overexpression of \u0394FosB enhances incentive for cocaine","volume":"23","author":"Colby","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0570","doi-asserted-by":"crossref","DOI":"10.1038\/nn1143","article-title":"Regulation of gene expression and cocaine reward by CREB and \u0394FosB","volume":"6","author":"McClung","year":"2003","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0575","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.4132-05.2006","article-title":"Cocaine increases actin cycling: effects in the reinstatement model of drug seeking","volume":"26","author":"Toda","year":"2006","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0580","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.5638-08.2009","article-title":"Altered dendritic spine plasticity in cocaine-withdrawn rats","volume":"29","author":"Shen","year":"2009","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0585","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M113.483487","article-title":"Methamphetamine-induced occludin endocytosis is mediated by the Arp2\/3 complex-regulated actin rearrangement","volume":"288","author":"Park","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0590","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2018.12.144","article-title":"Methamphetamine reduces expressions of tight junction proteins, rearranges F-actin cytoskeleton and increases the blood brain barrier permeability via the RhoA\/ROCK-dependent pathway","volume":"509","author":"Xue","year":"2019","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb0595","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-019-12122-8","article-title":"A novel role for the actin-binding protein drebrin in regulating opiate addiction","volume":"10","author":"Martin","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb0600","article-title":"Inhibition of actin polymerization in the NAc shell inhibits morphine-induced CPP by disrupting its reconsolidation","volume":"5","author":"Li","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2025.168059_bb0605","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a006247","article-title":"Biochemistry and cell biology of Tau protein in neurofibrillary degeneration","volume":"2","author":"Mandelkow","year":"2012","journal-title":"Cold Spring Harb. Perspect. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0610","doi-asserted-by":"crossref","DOI":"10.1001\/jama.287.9.1123","article-title":"Cognitive functioning of long-term heavy cannabis users seeking treatment","volume":"287","author":"Solowij","year":"2002","journal-title":"JAMA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0615","article-title":"Induction of hyperphosphorylated tau in primary rat cortical neuron cultures mediated by oxidative stress and glycogen synthase kinase-3","volume":"6","author":"Lovell","year":"2004","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0620","doi-asserted-by":"crossref","DOI":"10.1161\/01.STR.0000105929.88691.8E","article-title":"Alcohol intake and cerebral abnormalities on magnetic resonance imaging in a community-based population of middle-aged adults: the atherosclerosis risk in communities (ARIC) study","volume":"35","author":"Ding","year":"2004","journal-title":"Stroke"},{"key":"10.1016\/j.bbadis.2025.168059_bb0625","doi-asserted-by":"crossref","DOI":"10.1046\/j.1532-5415.2001.49085.x","article-title":"Alcohol abuse, cognitive impairment, and mortality among older people","volume":"49","author":"Thomas","year":"2001","journal-title":"J. Am. Geriatr. Soc."},{"key":"10.1016\/j.bbadis.2025.168059_bb0630","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2019.00288","article-title":"Effect of alcohol on hippocampal-dependent plasticity and behavior: role of glutamatergic synaptic transmission","volume":"13","author":"Mira","year":"2020","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0635","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2010.01.061","article-title":"The effects of alcoholism on the human basolateral amygdala","volume":"167","author":"Kryger","year":"2010","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2025.168059_bb0640","doi-asserted-by":"crossref","DOI":"10.1093\/alcalc\/agn100","article-title":"Biochemical and neurotransmitter changes implicated in alcohol-induced brain damage in chronic or \u201cbinge drinking\u201d alcohol abuse","volume":"44","author":"Ward","year":"2009","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0645","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2005.06.002","article-title":"Involvement of P2 receptors in the growth and survival of neurons in the CNS","volume":"109","author":"Franke","year":"2006","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbadis.2025.168059_bb0650","article-title":"Alcohol and Alzheimer\u2019s disease-does alcohol dependence contribute to beta-amyloid deposition, neuroinflammation and neurodegeneration in Alzheimer\u2019s disease?","volume":"52","author":"Venkataraman","year":"2017","journal-title":"Alcohol Alcohol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0655","article-title":"Alcohol use disorder and dementia: a review","volume":"44","author":"Zahr","year":"2024","journal-title":"Alcohol Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0660","doi-asserted-by":"crossref","DOI":"10.3233\/JAD-215508","article-title":"Chronic alcohol exposure alters gene expression and neurodegeneration pathways in the brain of adult mice","volume":"86","author":"Liu","year":"2022","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0665","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.0550-18.2018","article-title":"Alcohol consumption during adolescence in a mouse model of binge drinking alters the intrinsic excitability and function of the prefrontal cortex through a reduction in the hyperpolarization-activated cation current","volume":"38","author":"Salling","year":"2018","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0670","doi-asserted-by":"crossref","DOI":"10.3389\/fnbeh.2022.886634","article-title":"Chronic ethanol causes persistent increases in Alzheimer\u2019s tau pathology in female 3xTg-AD mice: a potential role for lysosomal impairment","volume":"16","author":"Tucker","year":"2022","journal-title":"Front. Behav. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0675","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbi.2023.12.034","article-title":"Binge ethanol exposure in advanced age elevates neuroinflammation and early indicators of neurodegeneration and cognitive impairment in female mice","volume":"116","author":"Anton","year":"2024","journal-title":"Brain Behav. Immun."},{"key":"10.1016\/j.bbadis.2025.168059_bb0680","doi-asserted-by":"crossref","DOI":"10.1038\/s41386-018-0202-x","article-title":"Glycogen synthase kinase 3 beta regulates ethanol consumption and is a risk factor for alcohol dependence","volume":"43","author":"van der Vaart","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0685","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-018-21341-w","article-title":"Binge alcohol exposure causes neurobehavioral deficits and GSK3\u03b2 activation in the hippocampus of adolescent rats","volume":"8","author":"Ji","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2025.168059_bb0690","doi-asserted-by":"crossref","DOI":"10.1111\/adb.70044","article-title":"A selective GSK3\u03b2 inhibitor, Tideglusib, decreases intermittent access and binge ethanol self-administration in C57BL\/6J mice","volume":"30","author":"Gottlieb","year":"2025","journal-title":"Addict. Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0695","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.2006.00160.x","article-title":"Neuroadaptations of Cdk5 in cholinergic interneurons of the nucleus accumbens and prefrontal cortex of inbred alcohol-preferring rats following voluntary alcohol drinking","volume":"30","author":"Camp","year":"2006","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0700","doi-asserted-by":"crossref","DOI":"10.1016\/S0304-3940(01)02011-0","article-title":"Ethanol induced changes in cyclin-dependent kinase-5 activity and its activators, P35, P67 (Munc-18) in rat brain","volume":"308","author":"Rajgopal","year":"2001","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb0705","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2022.07.007","article-title":"Ethanol sustains phosphorylated tau protein in the cultured neonatal rat hippocampus: implications for fetal alcohol spectrum disorders","volume":"103","author":"Bailey","year":"2022","journal-title":"Alcohol"},{"key":"10.1016\/j.bbadis.2025.168059_bb0710","doi-asserted-by":"crossref","DOI":"10.1111\/acer.15061","article-title":"Fetal alcohol exposure impairs learning and memory functions and elevates levels of various biochemical markers of Alzheimer\u2019s disease in the brain of 12-month-old rats","volume":"47","author":"Chaudhary","year":"2023","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0715","doi-asserted-by":"crossref","DOI":"10.1007\/s11064-009-0116-4","article-title":"Tau phosphorylation and cleavage in ethanol-induced neurodegeneration in the developing mouse brain","volume":"35","author":"Saito","year":"2010","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0720","doi-asserted-by":"crossref","DOI":"10.1038\/s41386-018-0181-y","article-title":"CB1R regulates CDK5 signaling and epigenetically controls Rac1 expression contributing to neurobehavioral abnormalities in mice postnatally exposed to ethanol","volume":"44","author":"Joshi","year":"2019","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0725","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0098080","article-title":"Ethanol-induced transcriptional activation of Programmed Cell Death 4 (Pdcd4) is mediated by GSK-3\u03b2 signaling in rat cortical neuroblasts","volume":"9","author":"Riar","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2025.168059_bb0730","doi-asserted-by":"crossref","DOI":"10.1017\/S0033291719001788","article-title":"Comorbidity of substance misuse with anxiety-related and depressive disorders: a genetically informative population study of 3 million individuals in Sweden","volume":"50","author":"Virtanen","year":"2020","journal-title":"Psychol. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0735","doi-asserted-by":"crossref","DOI":"10.1177\/00207640241232321","article-title":"Substance use and its association with mental health among Swiss medical students: a cross-sectional study","volume":"70","author":"Gaume","year":"2024","journal-title":"Int. J. Soc. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0740","article-title":"A systematic review of the cost-effectiveness of perampanel in the treatment of epilepsy","volume":"38","author":"Linh","year":"2022","journal-title":"VNU J. Sci. Med. Pharm. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0745","doi-asserted-by":"crossref","DOI":"10.1186\/s13722-020-0181-1","article-title":"Substance use disorders and risk of suicide in a general US population: a case control study","volume":"15","author":"Lynch","year":"2020","journal-title":"Addict. Sci. Clin. Pract."},{"key":"10.1016\/j.bbadis.2025.168059_bb0750","doi-asserted-by":"crossref","DOI":"10.1007\/s12640-025-00729-3","article-title":"Cannabidiol-induced autophagy ameliorates Tau protein clearance","volume":"43","author":"Vrechi","year":"2025","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0755","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxlet.2019.08.023","article-title":"Long-term ketamine administration causes tau protein phosphorylation and Tau protein-dependent AMPA receptor reduction in the hippocampus of mice","volume":"315","author":"Li","year":"2019","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb0760","article-title":"The pharmacological basis of opioids","volume":"12","author":"Ghelardini","year":"2015","journal-title":"Clin. Cases Miner. Bone Metab."},{"key":"10.1016\/j.bbadis.2025.168059_bb0765","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.0133-14.2014","article-title":"Endogenous opioid-induced neuroplasticity of dopaminergic neurons in the ventral tegmental area influences natural and opiate reward","volume":"34","author":"Pitchers","year":"2014","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0770","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuron.2011.10.012","article-title":"Role for mTOR signaling and neuronal activity in morphine-induced adaptations in ventral tegmental area dopamine neurons","volume":"72","author":"Mazei-Robison","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.bbadis.2025.168059_bb0775","doi-asserted-by":"crossref","DOI":"10.1038\/nn1812","article-title":"IRS2-Akt pathway in midbrain dopamine neurons regulates behavioral and cellular responses to opiates","volume":"10","author":"Russo","year":"2007","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0780","doi-asserted-by":"crossref","DOI":"10.3233\/JAD-170414","article-title":"Associations between use of specific analgesics and concentrations of amyloid-\u03b2 42 or phospho-tau in regions of human cerebral cortex","volume":"61","author":"Flanagan","year":"2017","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0785","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2012.09.040","article-title":"Effect of c-Jun N-terminal kinase (JNK)\/p38 mitogen-activated protein kinase (p38 MAPK) in morphine-induced tau protein hyperphosphorylation","volume":"237","author":"Cao","year":"2013","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0790","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-012-2666-4","article-title":"Neuropsychological effects associated with recreational cocaine use","volume":"222","author":"Soar","year":"2012","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0795","doi-asserted-by":"crossref","DOI":"10.1016\/S0740-5472(01)00192-1","article-title":"Cocaine dependence: a disease of the brain\u2019s reward centers","volume":"21","author":"Dackis","year":"2001","journal-title":"J. Subst. Abus. Treat."},{"key":"10.1016\/j.bbadis.2025.168059_bb0800","doi-asserted-by":"crossref","DOI":"10.1097\/ADM.0000000000000066","article-title":"Cocaine and cognition: a systematic quantitative review","volume":"8","author":"Potvin","year":"2014","journal-title":"J. Addict. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0805","doi-asserted-by":"crossref","DOI":"10.1038\/sj.npp.1300604","article-title":"Enhanced Cdk5 activity and p35 translocation in the ventral striatum of acute and chronic methamphetamine-treated rats","volume":"30","author":"Chen","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0810","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.2848-20.2021","article-title":"4R tau modulates cocaine-associated memory through adult dorsal hippocampal neurogenesis","volume":"41","author":"Li","year":"2021","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0815","article-title":"The Src-kinase Fyn is required for cocaine-associated memory through regulation of tau","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0820","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M112.401240","article-title":"Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation","volume":"287","author":"Mondrag\u00f3n-Rodr\u00edguez","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb0825","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2019.146556","article-title":"Of mice and men on MDMA: a translational comparison of the neuropsychobiological effects of 3,4-methylenedioxymethamphetamine (\u2018Ecstasy\u2019)","volume":"1727","author":"Aguilar","year":"2020","journal-title":"Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0830","doi-asserted-by":"crossref","DOI":"10.1007\/s00204-014-1209-7","article-title":"MDMA impairs mitochondrial neuronal trafficking in a Tau- and Mitofusin2\/Drp1-dependent manner","volume":"88","author":"Barbosa","year":"2014","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0835","doi-asserted-by":"crossref","DOI":"10.1177\/0269881119855987","article-title":"Effects of MDMA on neuroplasticity, amyloid burden and phospho-tau expression in APPswe\/PS1dE9 mice","volume":"33","author":"Abad","year":"2019","journal-title":"J. Psychopharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0840","doi-asserted-by":"crossref","DOI":"10.1007\/s00204-018-2226-8","article-title":"Aged rats are more vulnerable than adolescents to \u201cecstasy\u201d-induced toxicity","volume":"92","author":"Feio-Azevedo","year":"2018","journal-title":"Arch. Toxicol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0845","doi-asserted-by":"crossref","DOI":"10.1016\/j.euroneuro.2017.08.425","article-title":"Discrete memory impairments in largely pure chronic users of MDMA","volume":"27","author":"Wunderli","year":"2017","journal-title":"Eur. Neuropsychopharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0850","doi-asserted-by":"crossref","DOI":"10.1038\/s41386-018-0065-1","article-title":"Cognitive deficit in methamphetamine users relative to childhood academic performance: link to cortical thickness","volume":"43","author":"Dean","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0855","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2009.02.021","article-title":"Methamphetamine- and trauma-induced brain injuries: comparative cellular and molecular neurobiological substrates","volume":"66","author":"Gold","year":"2009","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0860","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-016-4283-0","article-title":"Chronic methamphetamine self-administration alters cognitive flexibility in male rats","volume":"233","author":"Cox","year":"2016","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0865","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbr.2016.12.010","article-title":"Effects of chronic methamphetamine on psychomotor and cognitive functions and dopamine signaling in the brain","volume":"320","author":"Thanos","year":"2017","journal-title":"Behav. Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0870","doi-asserted-by":"crossref","DOI":"10.1007\/s10339-017-0839-0","article-title":"Effect of three different regimens of repeated methamphetamine on rats\u2019 cognitive performance","volume":"19","author":"Seyedhosseini Tamijani","year":"2018","journal-title":"Cogn. Process."},{"key":"10.1016\/j.bbadis.2025.168059_bb0875","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2018.07.002","article-title":"Involvement of insulin signalling pathway in methamphetamine-induced hyperphosphorylation of Tau","volume":"408","author":"Xu","year":"2018","journal-title":"Toxicology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0880","doi-asserted-by":"crossref","DOI":"10.2131\/jts.44.493","article-title":"Methamphetamine exposure upregulates the amyloid precursor protein and hyperphosphorylated tau expression: the roles of insulin signaling in sh-sy5y cell line","volume":"44","author":"Chen","year":"2019","journal-title":"J. Toxicol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0885","doi-asserted-by":"crossref","DOI":"10.1093\/toxsci\/kfx093","article-title":"Insulin resistance disrupts the interaction between AKT and the NMDA receptor and the inactivation of the CaMKIV\/CREB pathway in minimal hepatic encephalopathy","volume":"159","author":"Ding","year":"2017","journal-title":"Toxicol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0890","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-022-02122-6","article-title":"Insulin signaling as a therapeutic mechanism of lithium in bipolar disorder","volume":"12","author":"Campbell","year":"2022","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb0895","doi-asserted-by":"crossref","DOI":"10.1111\/j.1460-9568.2006.04859.x","article-title":"Signalling mechanisms mediated by the phosphoinositide 3-kinase\/Akt cascade in synaptic plasticity and memory in the rat","volume":"23","author":"Horwood","year":"2006","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0900","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2018.05.050","article-title":"The profile of cognitive impairments in chronic ketamine users","volume":"266","author":"Ke","year":"2018","journal-title":"Psychiatry Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0905","doi-asserted-by":"crossref","DOI":"10.1093\/brain\/awq131","article-title":"Frontal white matter abnormalities following chronic ketamine use: a diffusion tensor imaging study","volume":"133","author":"Liao","year":"2010","journal-title":"Brain"},{"key":"10.1016\/j.bbadis.2025.168059_bb0910","article-title":"Long-term neurocognitive dysfunction in offspring via NGF\/ERK\/CREB signaling pathway caused by ketamine exposure during the second trimester of pregnancy in rats","volume":"8","author":"Li","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.bbadis.2025.168059_bb0915","doi-asserted-by":"crossref","DOI":"10.1186\/s40001-023-01443-6","article-title":"The synthetic cannabinoids menace: a review of health risks and toxicity","volume":"29","author":"Alzu\u2019bi","year":"2024","journal-title":"Eur. J. Med. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0920","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.87.5.1932","article-title":"Cannabinoid receptor localization in brain","volume":"87","author":"Herkenham","year":"1990","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbadis.2025.168059_bb0925","doi-asserted-by":"crossref","DOI":"10.1007\/s11920-016-0694-1","article-title":"Adverse effects of synthetic cannabinoids: management of acute toxicity and withdrawal","volume":"18","author":"Cooper","year":"2016","journal-title":"Curr. Psychiatry Rep."},{"key":"10.1016\/j.bbadis.2025.168059_bb0930","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1097\/MAJ.0000000000000466","article-title":"Synthetic cannabinoids","volume":"350","author":"Mills","year":"2015","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.bbadis.2025.168059_bb0935","doi-asserted-by":"crossref","DOI":"10.1016\/j.tips.2015.02.008","article-title":"Endocannabinoid signaling at the periphery: 50 years after THC","volume":"36","author":"Maccarrone","year":"2015","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0940","doi-asserted-by":"crossref","DOI":"10.1053\/j.gastro.2004.12.050","article-title":"Antifibrogenic role of the cannabinoid receptor CB2 in the liver","volume":"128","author":"Julien","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0945","doi-asserted-by":"crossref","DOI":"10.1189\/jlb.3HI1214-584R","article-title":"Human lung-resident macrophages express CB1 and CB2 receptors whose activation inhibits the release of angiogenic and lymphangiogenic factors","volume":"99","author":"Staiano","year":"2016","journal-title":"J. Leukoc. Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0950","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2004.01.039","article-title":"Cannabinoids reduce cAMP levels in the striatum of freely moving rats: an in vivo microdialysis study","volume":"1005","author":"Wade","year":"2004","journal-title":"Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb0955","doi-asserted-by":"crossref","DOI":"10.1016\/j.nbd.2022.105670","article-title":"Synaptic changes induced by cannabinoid drugs and cannabis use disorder","volume":"167","author":"Augustin","year":"2022","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb0960","doi-asserted-by":"crossref","DOI":"10.1007\/s00414-013-0864-1","article-title":"Driving under the influence of synthetic cannabinoids (\u201cSpice\u201d): a case series","volume":"128","author":"Musshoff","year":"2014","journal-title":"Int. J. Legal Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb0965","doi-asserted-by":"crossref","DOI":"10.1007\/s00213-017-4546-4","article-title":"The effects of synthetic cannabinoids on executive function","volume":"234","author":"Cohen","year":"2017","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0970","doi-asserted-by":"crossref","DOI":"10.1002\/hipo.20554","article-title":"Changes in hippocampal morphology and neuroplasticity induced by adolescent THC treatment are associated with cognitive impairment in adulthood","volume":"19","author":"Rubino","year":"2009","journal-title":"Hippocampus"},{"key":"10.1016\/j.bbadis.2025.168059_bb0975","doi-asserted-by":"crossref","DOI":"10.1038\/sj.bjp.0703413","article-title":"D2 dopamine receptors enable \u03949-tetrahydrocannabinol induced memory impairment and reduction of hippocampal extracellular acetylcholine concentration","volume":"130","author":"Nava","year":"2000","journal-title":"Br. J. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0980","doi-asserted-by":"crossref","DOI":"10.1038\/npp.2017.126","article-title":"Endocannabinoid regulation of reward and reinforcement through interaction with dopamine and endogenous opioid signaling","volume":"43","author":"Wenzel","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb0985","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2023.114384","article-title":"Endocannabinoid regulation of hippocampus-dependent memory","volume":"364","author":"Figueiredo","year":"2023","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbadis.2025.168059_bb0990","doi-asserted-by":"crossref","DOI":"10.1016\/j.autneu.2010.06.001","article-title":"Retrograde release of endocannabinoids inhibits presynaptic GABA release to second-order baroreceptive neurons in NTS","volume":"158","author":"Chen","year":"2010","journal-title":"Auton. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb0995","doi-asserted-by":"crossref","DOI":"10.1523\/JNEUROSCI.0736-10.2010","article-title":"Dopaminergic modulation of endocannabinoid-mediated plasticity at GABAergic synapses in the prefrontal cortex","volume":"30","author":"Chiu","year":"2010","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1000","doi-asserted-by":"crossref","DOI":"10.1093\/ijnp\/pyu024","article-title":"Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex","volume":"18","author":"Blanco","year":"2015","journal-title":"Int. J. Neuropsychopharmacol."},{"issue":"MAR","key":"10.1016\/j.bbadis.2025.168059_bb1005","article-title":"Cannabinoids for treatment of Alzheimer\u2019s disease: moving toward the clinic","volume":"5","author":"Aso","year":"2014","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1010","doi-asserted-by":"crossref","DOI":"10.3233\/JAD-2012-111862","article-title":"CB1 agonist ACEA protects neurons and reduces the cognitive impairment of A\u03b2PP\/PS1 mice","volume":"30","author":"Aso","year":"2012","journal-title":"J. Alzheimers Dis."},{"key":"10.1016\/j.bbadis.2025.168059_bb1015","doi-asserted-by":"crossref","DOI":"10.1016\/j.neulet.2006.06.012","article-title":"CB1 receptor selective activation inhibits \u03b2-amyloid-induced iNOS protein expression in C6 cells and subsequently blunts tau protein hyperphosphorylation in co-cultured neurons","volume":"404","author":"Esposito","year":"2006","journal-title":"Neurosci. Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb1020","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2018.11.058","article-title":"Cannabinoid type 2 receptor agonist JWH-133, attenuates Okadaic acid induced spatial memory impairment and neurodegeneration in rats","volume":"217","author":"\u00c7ak\u0131r","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1025","doi-asserted-by":"crossref","DOI":"10.1186\/s40478-021-01196-5","article-title":"Cannabinoid receptor CB2 ablation protects against TAU induced neurodegeneration","volume":"9","author":"Gal\u00e1n-Ganga","year":"2021","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb1030","doi-asserted-by":"crossref","DOI":"10.3390\/cells10123521","article-title":"Cannabidiol inhibits tau aggregation in vitro","volume":"10","author":"Alali","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2025.168059_bb1035","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2018.00441","article-title":"Contribution of Tau pathology to mitochondrial impairment in neurodegeneration","volume":"12","author":"P\u00e9rez","year":"2018","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1040","doi-asserted-by":"crossref","DOI":"10.1111\/jnc.15975","article-title":"Site-specific phosphorylation of tau impacts mitochondrial function and response to stressors","volume":"168","author":"Isei","year":"2024","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1045","doi-asserted-by":"crossref","DOI":"10.1042\/NS20200008","article-title":"Mechanisms and roles of mitochondrial localisation and dynamics in neuronal function","volume":"4","author":"Seager","year":"2020","journal-title":"Neuronal Signal"},{"key":"10.1016\/j.bbadis.2025.168059_bb1050","doi-asserted-by":"crossref","DOI":"10.1016\/j.mcn.2023.103861","article-title":"Cyclosporine a (CsA) prevents synaptic impairment caused by truncated tau by caspase-3","volume":"125","author":"Tapia-Monsalves","year":"2023","journal-title":"Mol. Cell. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1055","doi-asserted-by":"crossref","DOI":"10.1046\/j.1471-4159.2000.0751681.x","article-title":"Mitochondrial dysfunction in cybrid lines expressing mitochondrial genes from patients with progressive supranuclear palsy","volume":"75","author":"Swerdlow","year":"2000","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1060","doi-asserted-by":"crossref","DOI":"10.1046\/j.1471-4159.1994.62041631.x","article-title":"Rapid communication muscle mitochondrial ATP production in progressive supranuclear palsy","volume":"62","author":"Monte","year":"1994","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1065","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuint.2025.105991","article-title":"Sulforaphane prevents cognitive decline and mitochondrial failure induced by hippocampal expression of caspase-3 cleaved tau","volume":"187","author":"Villavicencio-Tejo","year":"2025","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bbadis.2025.168059_bb1070","doi-asserted-by":"crossref","DOI":"10.3390\/antiox11030515","article-title":"Activation of the Nrf2 pathway prevents mitochondrial dysfunction induced by caspase-3 cleaved tau: implications for Alzheimer\u2019s disease","volume":"11","author":"Villavicencio-Tejo","year":"2022","journal-title":"Antioxidants"},{"key":"10.1016\/j.bbadis.2025.168059_bb1075","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M808908200","article-title":"Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease","volume":"284","author":"Quintanilla","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1080","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2020.00175","article-title":"Truncated tau induces mitochondrial transport failure through the impairment of TRAK2 protein and bioenergetics decline in neuronal cells","volume":"14","author":"Quintanilla","year":"2020","journal-title":"Front. Cell. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1085","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.260993","article-title":"Aggregation-prone tau impairs mitochondrial import, which affects organelle morphology and neuronal complexity","volume":"136","author":"Needs","year":"2023","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1090","doi-asserted-by":"crossref","DOI":"10.1093\/hmg\/dds072","article-title":"Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer\u2019s disease neurons: implications for mitochondrial dysfunction and neuronal damage","volume":"21","author":"Manczak","year":"2012","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbadis.2025.168059_bb1095","doi-asserted-by":"crossref","DOI":"10.1002\/bdr2.1172","article-title":"Alcohol consumption during adolescence: a link between mitochondrial damage and ethanol brain intoxication","volume":"109","author":"Tapia-Rojas","year":"2017","journal-title":"Birth Defects Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb1100","doi-asserted-by":"crossref","DOI":"10.1016\/j.drugalcdep.2019.107628","article-title":"Alcohol impairs hippocampal function: from NMDA receptor synaptic transmission to mitochondrial function","volume":"205","author":"Mira","year":"2019","journal-title":"Drug Alcohol Depend."},{"key":"10.1016\/j.bbadis.2025.168059_bb1105","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2019.03.018","article-title":"Adolescence binge alcohol consumption induces hippocampal mitochondrial impairment that persists during the adulthood","volume":"406","author":"Tapia-Rojas","year":"2019","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2025.168059_bb1110","series-title":"Mitochondrial Intoxication","article-title":"The effects of alcohol abuse against the mitochondria: functional consequences for liver, muscle, and the brain","author":"Olesen","year":"2022"},{"key":"10.1016\/j.bbadis.2025.168059_bb1115","doi-asserted-by":"crossref","DOI":"10.1038\/s41398-024-02748-8","article-title":"Synaptic and mitochondrial mechanisms behind alcohol-induced imbalance of excitatory\/inhibitory synaptic activity and associated cognitive and behavioral abnormalities","volume":"14","author":"Arzua","year":"2024","journal-title":"Transl. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb1120","doi-asserted-by":"crossref","DOI":"10.1111\/j.1530-0277.1996.tb01141.x","article-title":"Binge ethanol-induced brain damage in rats: effect of inhibitors of nitric oxide synthase","volume":"20","author":"Zou","year":"1996","journal-title":"Alcohol. Clin. Exp. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb1125","doi-asserted-by":"crossref","DOI":"10.1007\/s10068-018-0472-4","article-title":"Protective effect of Carthamus tinctorius L. seed on oxidative stress and cognitive impairment induced by chronic alcohol consumption in mice","volume":"27","author":"Choi","year":"2018","journal-title":"Food Sci. Biotechnol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1130","doi-asserted-by":"crossref","DOI":"10.1186\/1742-2094-9-5","article-title":"NADPH oxidase and reactive oxygen species contribute to alcohol-induced microglial activation and neurodegeneration","volume":"9","author":"Qin","year":"2012","journal-title":"J. Neuroinflammation"},{"key":"10.1016\/j.bbadis.2025.168059_bb1135","doi-asserted-by":"crossref","DOI":"10.1016\/j.alcohol.2009.10.003","article-title":"Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence","volume":"44","author":"Guerri","year":"2010","journal-title":"Alcohol"},{"key":"10.1016\/j.bbadis.2025.168059_bb1140","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.108100","article-title":"NADPH oxidase contributes to oxidative damage and mitochondrial impairment induced by acute ethanol treatment in rat hippocampal neurons","volume":"171","author":"P\u00e9rez","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb1145","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-018-1268-5","article-title":"Adolescent binge alcohol exposure affects the brain function through mitochondrial impairment","volume":"55","author":"Tapia-Rojas","year":"2018","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1150","doi-asserted-by":"crossref","DOI":"10.1007\/s12035-022-03008-w","article-title":"Cdk5 promotes mitochondrial fission via Drp1 phosphorylation at S616 in chronic ethanol exposure\u2013induced cognitive impairment","volume":"59","author":"Liu","year":"2022","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1155","doi-asserted-by":"crossref","DOI":"10.1021\/tx300395w","article-title":"Mitochondrial permeability transition pore inhibitors prevent ethanol-induced neuronal death in mice","volume":"26","author":"Lamarche","year":"2013","journal-title":"Chem. Res. Toxicol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1160","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2015.07.012","article-title":"Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum","volume":"304","author":"Karadayian","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2025.168059_bb1165","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2020.561173","article-title":"Chronic alcohol exposure induces aberrant mitochondrial morphology and inhibits respiratory capacity in the medial prefrontal cortex of mice","volume":"14","author":"Shang","year":"2020","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1170","doi-asserted-by":"crossref","DOI":"10.1152\/physrev.1999.79.4.1127","article-title":"Mitochondrial transport of cations: channels, exchangers, and permeability transition","volume":"79","author":"Bernardi","year":"1999","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbadis.2025.168059_bb1175","article-title":"Inhibition by cyclosporin A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress","volume":"255","author":"Crompton","year":"1988","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbadis.2025.168059_bb1180","doi-asserted-by":"crossref","DOI":"10.1016\/j.yjmcc.2009.02.021","article-title":"What is the mitochondrial permeability transition pore?","volume":"46","author":"Halestrap","year":"2009","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1185","doi-asserted-by":"crossref","DOI":"10.1038\/s41418-023-01187-0","article-title":"Identity, structure, and function of the mitochondrial permeability transition pore: controversies, consensus, recent advances, and future directions","volume":"30","author":"Bernardi","year":"2023","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbadis.2025.168059_bb1190","doi-asserted-by":"crossref","DOI":"10.1016\/j.ydbio.2017.04.018","article-title":"Development or disease: duality of the mitochondrial permeability transition pore","volume":"426","author":"P\u00e9rez","year":"2017","journal-title":"Dev. Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1195","doi-asserted-by":"crossref","DOI":"10.1007\/s12311-014-0598-8","article-title":"Alcohol withdrawal and cerebellar mitochondria","volume":"14","author":"Jung","year":"2015","journal-title":"Cerebellum"},{"key":"10.1016\/j.bbadis.2025.168059_bb1200","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroscience.2020.05.005","article-title":"Stimulation of melanocortin receptor-4 (MC4R) prevents mitochondrial damage induced by binge ethanol protocol in adolescent rat hippocampus","volume":"438","author":"Torres","year":"2020","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbadis.2025.168059_bb1205","doi-asserted-by":"crossref","DOI":"10.1007\/s12640-020-00204-1","article-title":"Activation of the melanocortin-4 receptor prevents oxidative damage and mitochondrial dysfunction in cultured hippocampal neurons exposed to ethanol","volume":"38","author":"Quintanilla","year":"2020","journal-title":"Neurotox. Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb1210","doi-asserted-by":"crossref","DOI":"10.1038\/nn1455","article-title":"Anatomy and regulation of the central melanocortin system","volume":"8","author":"Cone","year":"2005","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1215","doi-asserted-by":"crossref","DOI":"10.1038\/s41574-023-00855-y","article-title":"Targeting the central melanocortin system for the treatment of metabolic disorders","volume":"19","author":"Sweeney","year":"2023","journal-title":"Nat. Rev. Endocrinol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1220","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0019107","article-title":"Role of hypothalamic melanocortin system in adaptation of food intake to food protein increase in mice","volume":"6","author":"Pillot","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2025.168059_bb1225","doi-asserted-by":"crossref","DOI":"10.1016\/j.expneurol.2021.113795","article-title":"Neurotoxicity of methamphetamine: main effects and mechanisms","volume":"344","author":"Jayanthi","year":"2021","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1230","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0005546","article-title":"Mitochondrial fragmentation is involved in methamphetamine-induced cell death in rat hippocampal neural progenitor cells","volume":"4","author":"Tian","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2025.168059_bb1235","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23168926","article-title":"Alterations of mitochondrial structure in methamphetamine toxicity","volume":"23","author":"Lenzi","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1240","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-021-04301-9","article-title":"Mitochondrial function influences expression of methamphetamine-induced behavioral sensitization","volume":"11","author":"Calma","year":"2021","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2025.168059_bb1245","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuro.2019.09.001","article-title":"Repeated exposure of cocaine alters mitochondrial dynamics in mouse neuroblastoma Neuro2a","volume":"75","author":"Funakoshi","year":"2019","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.bbadis.2025.168059_bb1250","doi-asserted-by":"crossref","DOI":"10.3390\/ijms26052131","article-title":"Cocaine differentially affects mitochondrial function depending on exposure time","volume":"26","author":"Wattad","year":"2025","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1255","article-title":"The role of mitochondria in cocaine addiction","volume":"478","author":"Thornton","year":"2021","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbadis.2025.168059_bb1260","doi-asserted-by":"crossref","DOI":"10.1080\/15548627.2019.1607686","article-title":"Mitigation of cocaine-mediated mitochondrial damage, defective mitophagy and microglial activation by superoxide dismutase mimetics","volume":"16","author":"Thangaraj","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2025.168059_bb1265","doi-asserted-by":"crossref","DOI":"10.1186\/s13041-021-00800-y","article-title":"Cocaine-induced neuron subtype mitochondrial dynamics through Egr3 transcriptional regulation","volume":"14","author":"Cole","year":"2021","journal-title":"Mol. Brain"},{"key":"10.1016\/j.bbadis.2025.168059_bb1270","doi-asserted-by":"crossref","DOI":"10.1172\/JCI171995","article-title":"Targeting mitochondrial dynamics of morphine-responsive dopaminergic neurons ameliorates opiate withdrawal","volume":"134","author":"Jiang","year":"2024","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2025.168059_bb1275","doi-asserted-by":"crossref","DOI":"10.1016\/j.toxlet.2014.09.002","article-title":"Cannabinoid-induced changes in respiration of brain mitochondria","volume":"231","author":"Fi\u0161ar","year":"2014","journal-title":"Toxicol. Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb1280","article-title":"Cannabidiol impairs brain mitochondrial metabolism and neuronal integrity","volume":"8","author":"Drummond-Main","year":"2023","journal-title":"Cannabis Cannabinoid Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb1285","doi-asserted-by":"crossref","DOI":"10.1016\/S0305-7372(03)00081-1","article-title":"The proteasome: structure, function, and role in the cell","volume":"29","author":"Adams","year":"2003","journal-title":"Cancer Treat. Rev."},{"key":"10.1016\/j.bbadis.2025.168059_bb1290","doi-asserted-by":"crossref","DOI":"10.1016\/j.chembiol.2021.04.003","article-title":"The proteasome and its role in the nervous system","volume":"28","author":"T\u00fcrker","year":"2021","journal-title":"Cell Chem. Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1295","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurobiolaging.2017.12.001","article-title":"Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner","volume":"63","author":"Tang","year":"2018","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbadis.2025.168059_bb1300","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbrc.2014.10.066","article-title":"NDP52 associates with phosphorylated tau in brains of an Alzheimer disease mouse model","volume":"454","author":"Kim","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb1305","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms4496","article-title":"Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52","volume":"5","author":"Jo","year":"2014","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2025.168059_bb1310","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.106.5.1583","article-title":"Regulation of microtubule protein levels during cellular morphogenesis in nerve growth factor-treated PC12 cells","volume":"106","author":"Drubin","year":"1988","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbadis.2025.168059_bb1315","article-title":"Phosphorylation inhibits turnover of the tau protein by the proteasome: influence of RCAN1 and oxidative stress","volume":"400","author":"Poppek","year":"2006","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbadis.2025.168059_bb1320","doi-asserted-by":"crossref","DOI":"10.1016\/j.febslet.2007.02.065","article-title":"Effects of tau phosphorylation on proteasome activity","volume":"581","author":"Ren","year":"2007","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbadis.2025.168059_bb1325","doi-asserted-by":"crossref","DOI":"10.1038\/nm.4011","article-title":"Tau-driven 26S proteasome impairment and cognitive dysfunction can be prevented early in disease by activating cAMP-PKA signaling","volume":"22","author":"Myeku","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbadis.2025.168059_bb1330","doi-asserted-by":"crossref","DOI":"10.1016\/j.abb.2010.05.008","article-title":"Tau protein degradation is catalyzed by the ATP\/ubiquitin-independent 20S proteasome under normal cell conditions","volume":"500","author":"Grune","year":"2010","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbadis.2025.168059_bb1335","doi-asserted-by":"crossref","DOI":"10.1016\/j.neurobiolaging.2014.08.012","article-title":"BAG3 facilitates the clearance of endogenous tau in primary neurons","volume":"36","author":"Lei","year":"2015","journal-title":"Neurobiol. Aging"},{"key":"10.1016\/j.bbadis.2025.168059_bb1340","doi-asserted-by":"crossref","DOI":"10.1016\/j.arr.2020.101078","article-title":"Ubiquitin biology in neurodegenerative disorders: from impairment to therapeutic strategies","volume":"61","author":"Kumar","year":"2020","journal-title":"Ageing Res. Rev."},{"key":"10.1016\/j.bbadis.2025.168059_bb1345","doi-asserted-by":"crossref","DOI":"10.1038\/npp.2015.156","article-title":"Response of the ubiquitin-proteasome system to memory retrieval after extended-access cocaine or saline self-administration","volume":"40","author":"Werner","year":"2015","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.bbadis.2025.168059_bb1350","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopsych.2018.07.013","article-title":"E3 ubiquitin-protein ligase SMURF1 in the nucleus Accumbens mediates cocaine seeking","volume":"84","author":"Werner","year":"2018","journal-title":"Biol. Psychiatry"},{"key":"10.1016\/j.bbadis.2025.168059_bb1355","doi-asserted-by":"crossref","DOI":"10.1111\/j.1471-4159.2010.07147.x","article-title":"Methamphetamine oxidatively damages parkin and decreases the activity of 26S proteasome in vivo","volume":"116","author":"Moszczynska","year":"2011","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1360","doi-asserted-by":"crossref","DOI":"10.1016\/j.molbrainres.2004.09.018","article-title":"Proteomic analysis of phosphotyrosyl proteins in morphine-dependent rat brains","volume":"133","author":"Kim","year":"2005","journal-title":"Mol. Brain Res."},{"key":"10.1016\/j.bbadis.2025.168059_bb1365","doi-asserted-by":"crossref","DOI":"10.3390\/molecules27238321","article-title":"Effects of different opioid drugs on oxidative status and proteasome activity in SH-SY5Y cells","volume":"27","author":"Rullo","year":"2022","journal-title":"Molecules"},{"key":"10.1016\/j.bbadis.2025.168059_bb1370","doi-asserted-by":"crossref","DOI":"10.1074\/jbc.M800809200","article-title":"Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation","volume":"283","author":"Yang","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbadis.2025.168059_bb1375","doi-asserted-by":"crossref","DOI":"10.1186\/1477-5956-4-23","article-title":"Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis","volume":"4","author":"Neasta","year":"2006","journal-title":"Proteome Sci."},{"key":"10.1016\/j.bbadis.2025.168059_bb1380","doi-asserted-by":"crossref","DOI":"10.1016\/j.pain.2008.09.028","article-title":"Inhibition of the ubiquitin-proteasome activity prevents glutamate transporter degradation and morphine tolerance","volume":"140","author":"Yang","year":"2008","journal-title":"Pain"},{"key":"10.1016\/j.bbadis.2025.168059_bb1385","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.2922","article-title":"The roles of ubiquitin\u2013proteasome system and regulator of G protein signaling 4 in behavioral sensitization induced by a single morphine exposure","volume":"13","author":"Wang","year":"2023","journal-title":"Brain Behav."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925004077?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443925004077?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T06:14:28Z","timestamp":1773123268000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443925004077"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":277,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S0925443925004077"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.168059","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Is tau pathology a relevant factor in neuronal damage induced by alcohol and other drugs?","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2025.168059","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"168059"}}