{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:54:58Z","timestamp":1791060898981,"version":"4.1.0"},"reference-count":55,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["24JCQNJC02080"],"award-info":[{"award-number":["24JCQNJC02080"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["25JCZDJC00520"],"award-info":[{"award-number":["25JCZDJC00520"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["23JCQNJC00400"],"award-info":[{"award-number":["23JCQNJC00400"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["22JCZDJC00520"],"award-info":[{"award-number":["22JCZDJC00520"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170630"],"award-info":[{"award-number":["82170630"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200938"],"award-info":[{"award-number":["32200938"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82470660"],"award-info":[{"award-number":["82470660"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32171125"],"award-info":[{"award-number":["32171125"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81971331"],"award-info":[{"award-number":["81971331"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.bbadis.2026.168170","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T20:11:40Z","timestamp":1769544700000},"page":"168170","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"title":["ATP6V0d2 alleviates acute liver injury via promoting hepatocyte autophagy"],"prefix":"10.1016","volume":"1872","author":[{"given":"Mengxia","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhemin","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kefei","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuying","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianan","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiajun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2026.168170_bb0005","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.jhep.2023.03.017","article-title":"Global burden of liver disease: 2023 update","volume":"79","author":"Devarbhavi","year":"2023","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0010","doi-asserted-by":"crossref","DOI":"10.1186\/s13054-020-03327-1","article-title":"Gut-liver crosstalk in sepsis-induced liver injury","volume":"24","author":"Sun","year":"2020","journal-title":"Crit. Care"},{"key":"10.1016\/j.bbadis.2026.168170_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2025.168053","article-title":"Curcumin protects against PIICS-induced liver injury by suppressing iron-induced lipid peroxidation: insights from network pharmacology and experimental validation","volume":"1872","author":"Chen","year":"2026","journal-title":"Biochim. Biophys. Acta. Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2026.168170_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2024.167575","article-title":"Isorhapontigenin alleviates acetaminophen-induced liver injury by promoting fatty acid oxidation","volume":"1871","author":"Zha","year":"2025","journal-title":"Biochim. Biophys. Acta. Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2026.168170_bb0025","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1002\/2211-5463.13383","article-title":"The dynamics of cell death patterns and regeneration during acute liver injury in mice","volume":"12","author":"Shao","year":"2022","journal-title":"FEBS Open Bio."},{"key":"10.1016\/j.bbadis.2026.168170_bb0030","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.jhep.2019.10.013","article-title":"Effect of the clinical course of acute-on-chronic liver failure prior to liver transplantation on post-transplant survival","volume":"72","author":"Sundaram","year":"2020","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0035","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1111\/liv.13866","article-title":"Role and mechanisms of autophagy in acetaminophen-induced liver injury","volume":"38","author":"Chao","year":"2018","journal-title":"Liver Int."},{"key":"10.1016\/j.bbadis.2026.168170_bb0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2021.100973","article-title":"Autophagy in liver diseases: a review","volume":"82","author":"Qian","year":"2021","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.bbadis.2026.168170_bb0045","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jhep.2022.03.031","article-title":"Rare ATG7 genetic variants predispose patients to severe fatty liver disease","volume":"77","author":"Baselli","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0050","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1016\/j.jhep.2014.05.033","article-title":"Adiponectin protects against acetaminophen-induced mitochondrial dysfunction and acute liver injury by promoting autophagy in mice","volume":"61","author":"Lin","year":"2014","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellsig.2024.111379","article-title":"Fibroblast growth factor 21 alleviates acetaminophen induced acute liver injury by activating Sirt1 mediated autophagy","volume":"123","author":"Xu","year":"2024","journal-title":"Cell. Signal."},{"key":"10.1016\/j.bbadis.2026.168170_bb0060","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-017-09045-z","article-title":"Activation of autophagy attenuates EtOH-LPS-induced hepatic steatosis and injury through MD2 associated TLR4 signaling","volume":"7","author":"Kong","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2026.168170_bb0065","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.bbrc.2016.01.186","article-title":"Group IVA phospholipase A(2) deficiency prevents CCl4-induced hepatic cell death through the enhancement of autophagy","volume":"471","author":"Ishihara","year":"2016","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2026.168170_bb0070","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1007\/978-981-10-7757-9_14","article-title":"The vacuolar ATPase - a nano-scale motor that drives cell biology","volume":"87","author":"Harrison","year":"2018","journal-title":"Subcell. Biochem."},{"key":"10.1016\/j.bbadis.2026.168170_bb0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.molcel.2020.09.029","article-title":"Structures of a complete human V-ATPase reveal mechanisms of its assembly","volume":"80","author":"Wang","year":"2020","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbadis.2026.168170_bb0080","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.pep.2014.03.001","article-title":"Expression, purification and characterization of human vacuolar-type H(+)-ATPase subunit d1 and d2 in Escherichia coli","volume":"98","author":"Lim","year":"2014","journal-title":"Protein Expr. Purif."},{"key":"10.1016\/j.bbadis.2026.168170_bb0085","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/S0378-1119(02)00884-3","article-title":"Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosis","volume":"297","author":"Smith","year":"2002","journal-title":"Gene"},{"issue":"2021","key":"10.1016\/j.bbadis.2026.168170_bb0090","article-title":"Inhibiting ATP6V0D2 aggravates liver ischemia-reperfusion injury by promoting NLRP3 activation via impairing autophagic flux independent of Notch1\/Hes1","author":"Wang","year":"2021","journal-title":"J. Immunol. Res."},{"key":"10.1016\/j.bbadis.2026.168170_bb0095","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1080\/15548627.2019.1569916","article-title":"The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion","volume":"15","author":"Xia","year":"2019","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2026.168170_bb0100","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s13238-019-0636-x","article-title":"Atp6v0d2 mediates leucine-induced mTORC1 activation and polarization of macrophages","volume":"10","author":"Li","year":"2019","journal-title":"Protein Cell"},{"key":"10.1016\/j.bbadis.2026.168170_bb0105","doi-asserted-by":"crossref","first-page":"479","DOI":"10.4168\/aair.2021.13.3.479","article-title":"ATP6V0d2 suppresses alveoli macrophage alternative polarization and allergic asthma via degradation of PU.1","volume":"13","author":"Liu","year":"2021","journal-title":"Allergy Asthma Immunol. Res."},{"key":"10.1016\/j.bbadis.2026.168170_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.cmet.2021.03.006","article-title":"Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation","volume":"33","author":"Shen","year":"2021","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbadis.2026.168170_bb0115","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1038\/s41467-017-00204-4","article-title":"The liver-enriched lnc-LFAR1 promotes liver fibrosis by activating TGF\u03b2 and notch pathways","volume":"8","author":"Zhang","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2026.168170_bb0120","doi-asserted-by":"crossref","DOI":"10.1111\/acel.70212","article-title":"GPR65 functions as a key factor of bone aging and a novel therapeutic target for osteoporosis","volume":"24","author":"Zhang","year":"2025","journal-title":"Aging Cell"},{"key":"10.1016\/j.bbadis.2026.168170_bb0125","doi-asserted-by":"crossref","DOI":"10.1186\/s12967-025-06619-8","article-title":"GPR56 function as a key repressor in hepatocyte pyroptosis and the pathogenesis of liver fibrosis","volume":"23","author":"Shi","year":"2025","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bbadis.2026.168170_bb0130","article-title":"Targeting GPR65 alleviates hepatic inflammation and fibrosis by suppressing the JNK and NF-kappaB pathways","volume":"10","author":"Zhang","year":"2023","journal-title":"Mil. Med. Res."},{"key":"10.1016\/j.bbadis.2026.168170_bb0135","doi-asserted-by":"crossref","DOI":"10.1186\/s11658-023-00492-3","article-title":"LncRNA Helf promotes hepatic inflammation and fibrosis by interacting with PTBP1 to facilitate PIK3R5 mRNA stabilization","volume":"28","author":"Han","year":"2023","journal-title":"Cell. Mol. Biol. Lett."},{"key":"10.1016\/j.bbadis.2026.168170_bb0140","doi-asserted-by":"crossref","DOI":"10.1186\/s12916-022-02523-w","article-title":"LncRNA Airn maintains LSEC differentiation to alleviate liver fibrosis via the KLF2-eNOS-sGC pathway","volume":"20","author":"Chen","year":"2022","journal-title":"BMC Med."},{"key":"10.1016\/j.bbadis.2026.168170_bb0145","article-title":"Silencing lncRNA Lfar1 alleviates the classical activation and pyoptosis of macrophage in hepatic fibrosis","volume":"11","author":"Zhang","year":"2020","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bbadis.2026.168170_bb0150","doi-asserted-by":"crossref","DOI":"10.1136\/egastro-2024-100115","article-title":"Mechanistic role of long non-coding RNAs in the pathogenesis of metabolic dysfunction-associated steatotic liver disease and fibrosis","volume":"2","author":"Wade","year":"2024","journal-title":"eGastroenterology"},{"key":"10.1016\/j.bbadis.2026.168170_bb0155","doi-asserted-by":"crossref","DOI":"10.1136\/egastro-2023-100020","article-title":"Recent insights into the pathogenesis and therapeutic targets of chronic liver diseases","volume":"1","author":"Wen","year":"2023","journal-title":"eGastroenterology"},{"key":"10.1016\/j.bbadis.2026.168170_bb0160","doi-asserted-by":"crossref","DOI":"10.1038\/s41572-019-0105-0","article-title":"Drug-induced liver injury","volume":"5","author":"Andrade","year":"2019","journal-title":"Nat. Rev. Dis. Primers."},{"key":"10.1016\/j.bbadis.2026.168170_bb0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2025.167748","article-title":"Hepatic microRNA-320 restrains ferroptosis to mitigate acute-on-chronic alcohol-induced liver injury","volume":"1871","author":"Li","year":"2025","journal-title":"Biochim. Biophys. Acta. Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2026.168170_bb0170","doi-asserted-by":"crossref","DOI":"10.59717\/j.xinn-med.2024.100064","article-title":"New-onset age of metabolic-associated fatty liver disease and incident cardiovascular diseases: findings from prospective cohort","volume":"2","author":"Zheng","year":"2024","journal-title":"Innov. Med."},{"key":"10.1016\/j.bbadis.2026.168170_bb0175","doi-asserted-by":"crossref","first-page":"869","DOI":"10.1016\/S0140-6736(19)31894-X","article-title":"Acute liver failure","volume":"394","author":"Stravitz","year":"2019","journal-title":"Lancet"},{"key":"10.1016\/j.bbadis.2026.168170_bb0180","doi-asserted-by":"crossref","DOI":"10.1002\/ctm2.392","article-title":"A novel RANKL-targeted flavonoid glycoside prevents osteoporosis through inhibiting NFATc1 and reactive oxygen species","volume":"11","author":"Hong","year":"2021","journal-title":"Clin. Transl. Med."},{"key":"10.1016\/j.bbadis.2026.168170_bb0185","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.12955","article-title":"The calcium channel TRPV6 is a novel regulator of RANKL-induced osteoclastic differentiation and bone absorption activity through the IGF-PI3K-AKT pathway","volume":"54","author":"Ma","year":"2021","journal-title":"Cell Prolif."},{"key":"10.1016\/j.bbadis.2026.168170_bb0190","doi-asserted-by":"crossref","DOI":"10.3390\/biom12020256","article-title":"Effect on osteoclast differentiation and ER stress downregulation by amygdalin and RANKL binding interaction","volume":"12","author":"Trang","year":"2022","journal-title":"Biomolecules"},{"key":"10.1016\/j.bbadis.2026.168170_bb0195","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1095\/biolreprod.105.043752","article-title":"Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymis","volume":"74","author":"Pietrement","year":"2006","journal-title":"Biol. Reprod."},{"key":"10.1016\/j.bbadis.2026.168170_bb0200","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1165\/rcmb.2020-0349OC","article-title":"V-type ATPase mediates airway surface liquid acidification in pig small airway epithelial cells","volume":"65","author":"Li","year":"2021","journal-title":"Am. J. Respir. Cell Mol. Biol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2025.115088","article-title":"Macrophages Atp6v0d2 regulates XBP1-mediated cholesterol metabolism to suppress metabolic dysfunction-associated steatohepatitis progression","volume":"161","author":"Wang","year":"2025","journal-title":"Int. Immunopharmacol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0210","doi-asserted-by":"crossref","DOI":"10.1136\/egastro-2023-100024","article-title":"Macrophages clear out necrotic liver lesions: a new magic trick revealed","volume":"1","author":"Rodrigues","year":"2023","journal-title":"eGastroenterology"},{"key":"10.1016\/j.bbadis.2026.168170_bb0215","doi-asserted-by":"crossref","DOI":"10.3390\/cells8010016","article-title":"Relevance of autophagy in parenchymal and non-parenchymal liver cells for health and disease","volume":"8","author":"Weiskirchen","year":"2019","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2026.168170_bb0220","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/cr.2013.168","article-title":"The machinery of macroautophagy","volume":"24","author":"Feng","year":"2014","journal-title":"Cell Res."},{"key":"10.1016\/j.bbadis.2026.168170_bb0225","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1038\/s41583-022-00588-3","article-title":"Macroautophagy in CNS health and disease","volume":"23","author":"Griffey","year":"2022","journal-title":"Nat. Rev. Neurosci."},{"key":"10.1016\/j.bbadis.2026.168170_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.bbadis.2023.166824","article-title":"Metastatic outgrowth via the two-way interplay of autophagy and metabolism","volume":"1870","author":"Behrooz","year":"2024","journal-title":"Biochim. Biophys. Acta. Mol. Basis Dis."},{"key":"10.1016\/j.bbadis.2026.168170_bb0235","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1016\/j.jhep.2021.10.014","article-title":"Hepatocytic p62 suppresses ductular reaction and tumorigenesis in mouse livers with mTORC1 activation and defective autophagy","volume":"76","author":"Chao","year":"2022","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0240","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.trecan.2021.05.003","article-title":"Autophagy regulates stress responses, metabolism, and anticancer immunity","volume":"7","author":"E. White","year":"2021","journal-title":"Trends Cancer"},{"key":"10.1016\/j.bbadis.2026.168170_bb0245","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1080\/15548627.2019.1628538","article-title":"PLA2G4A\/cPLA2-mediated lysosomal membrane damage leads to inhibition of autophagy and neurodegeneration after brain trauma","volume":"16","author":"Sarkar","year":"2020","journal-title":"Autophagy"},{"key":"10.1016\/j.bbadis.2026.168170_bb0250","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/cmi.2015.97","article-title":"Hepatocytes: a key cell type for innate immunity","volume":"13","author":"Zhou","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.bbadis.2026.168170_bb0255","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1161\/CIRCRESAHA.116.303791","article-title":"Therapeutic targeting of autophagy: potential and concerns in treating cardiovascular disease","volume":"116","author":"Orogo","year":"2015","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbadis.2026.168170_bb0260","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1038\/nature07383","article-title":"Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production","volume":"456","author":"Saitoh","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.bbadis.2026.168170_bb0265","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/j.cmet.2006.01.011","article-title":"Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62","volume":"3","author":"Rodriguez","year":"2006","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbadis.2026.168170_bb0270","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1007\/s13238-015-0195-8","article-title":"Atg7 in development and disease: panacea or Pandora\u2019s box?","volume":"6","author":"Xiong","year":"2015","journal-title":"Protein Cell"},{"key":"10.1016\/j.bbadis.2026.168170_bb0275","doi-asserted-by":"crossref","first-page":"2549","DOI":"10.1080\/15548627.2020.1834711","article-title":"TXNIP\/VDUP1 attenuates steatohepatitis via autophagy and fatty acid oxidation","volume":"17","author":"Park","year":"2021","journal-title":"Autophagy"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443926000189?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443926000189?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T20:20:57Z","timestamp":1791058857000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443926000189"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":55,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4]]}},"alternative-id":["S0925443926000189"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2026.168170","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"ATP6V0d2 alleviates acute liver injury via promoting hepatocyte autophagy","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2026.168170","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"168170"}}