{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T14:18:54Z","timestamp":1792592334423,"version":"4.5.0"},"reference-count":203,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32270068"],"award-info":[{"award-number":["32270068"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC3602000"],"award-info":[{"award-number":["2022YFC3602000"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.bbadis.2026.168274","type":"journal-article","created":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T23:36:17Z","timestamp":1776900977000},"page":"168274","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Shared pathogenic mechanisms between systemic lupus erythematosus and autoimmune hepatitis: A unified view of autoimmune convergence"],"prefix":"10.1016","volume":"1872","author":[{"given":"Yechen","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengjiao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lanlan","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanfei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lanjuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbadis.2026.168274_bb0005","doi-asserted-by":"crossref","first-page":"2028","DOI":"10.1053\/gast.1997.v112.pm9178696","article-title":"Allelic basis for HLA-encoded susceptibility to type 1 autoimmune hepatitis","volume":"112","author":"Strettell","year":"1997","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbadis.2026.168274_bb0010","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1038\/gene.2014.82","article-title":"HLA-DRB1*03:01 and HLA-DRB1*04:01 modify the presentation and outcome in autoimmune hepatitis type-1","volume":"16","author":"van Gerven","year":"2015","journal-title":"Genes Immun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0015","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1002\/hep.1840130415","article-title":"Susceptibility to autoimmune chronic active hepatitis: human leukocyte antigens DR4 and A1-B8-DR3 are independent risk factors","volume":"13","author":"Donaldson","year":"1991","journal-title":"Hepatol (Baltim Md,)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0020","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/s42003-022-03717-x","article-title":"The lupus susceptibility allele DRB1*03:01 encodes a disease-driving epitope","volume":"5","author":"Miglioranza Scavuzzi","year":"2022","journal-title":"Commun. Biol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0025","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.ajhg.2012.08.026","article-title":"Unraveling multiple MHC gene associations with systemic lupus erythematosus: model choice indicates a role for HLA alleles and non-HLA genes in europeans","volume":"91","author":"Morris","year":"2012","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0030","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1002\/hep.510300412","article-title":"Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis","volume":"30","author":"Cookson","year":"1999","journal-title":"Hepatol (Baltim Md,)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0035","doi-asserted-by":"crossref","first-page":"153","DOI":"10.21037\/atm-20-8036","article-title":"Clinical characteristics and HLA genotypes in Chinese patients with anti-SLA\/LP-positive autoimmune hepatitis","volume":"9","author":"Zhang","year":"2021","journal-title":"Ann. Transl. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0040","doi-asserted-by":"crossref","first-page":"1502","DOI":"10.1016\/0016-5085(93)90157-8","article-title":"Significance of HLA DR4 in type 1 autoimmune hepatitis","volume":"105","author":"Czaja","year":"1993","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbadis.2026.168274_bb0045","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1186\/s12876-015-0360-9","article-title":"Evaluation of the role of HLA-DR antigens in japanese type 1 autoimmune hepatitis","volume":"15","author":"Furumoto","year":"2015","journal-title":"BMC Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0050","doi-asserted-by":"crossref","first-page":"1172","DOI":"10.1093\/rheumatology\/kes427","article-title":"An association analysis of HLA-DRB1 with systemic lupus erythematosus and rheumatoid arthritis in a Japanese population: effects of *09:01 allele on disease phenotypes","volume":"52","author":"Shimane","year":"2013","journal-title":"Rheumatol (oxf Engl)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0055","first-page":"1032","article-title":"HLA-DRB1*0401\/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity","volume":"22","author":"MacGregor","year":"1995","journal-title":"J. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0060","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1053\/j.gastro.2014.04.022","article-title":"Genome-wide association study identifies variants associated with autoimmune hepatitis type 1","volume":"147","author":"de Boer","year":"2014","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbadis.2026.168274_bb0065","doi-asserted-by":"crossref","first-page":"2868","DOI":"10.1093\/hmg\/ddn184","article-title":"A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5","volume":"17","author":"Sigurdsson","year":"2008","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0070","doi-asserted-by":"crossref","first-page":"2403","DOI":"10.1007\/s10067-024-07046-8","article-title":"Genetic polymorphisms in genes involved in the type I interferon system (STAT4 and IRF5): association with asian SLE patients","volume":"43","author":"Liu","year":"2024","journal-title":"Clin. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0075","doi-asserted-by":"crossref","DOI":"10.1038\/srep29770","article-title":"Genetic association of PTPN22 polymorphisms with autoimmune hepatitis and primary biliary cholangitis in Japan","volume":"6","author":"Umemura","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2026.168274_bb0080","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.yexmp.2018.10.001","article-title":"Association of STAT4, TGF\u03b21, SH2B3 and PTPN22 polymorphisms with autoimmune hepatitis","volume":"105","author":"Chaouali","year":"2018","journal-title":"Exp. Mol. Pathol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0085","doi-asserted-by":"crossref","first-page":"66","DOI":"10.11648\/j.iji.20170504.12","article-title":"CTLA-4, ICOS, PD1and PTPN22 gene polymorphisms and susceptibility to autoimmune hepatitis type 1","volume":"5","author":"Del Pilar","year":"2017","journal-title":"Int. J. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0090","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1086\/423790","article-title":"Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE","volume":"75","author":"Kyogoku","year":"2004","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0095","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1016\/j.humimm.2016.04.021","article-title":"PTPN22 polymorphisms, but not R620W, were associated with the genetic susceptibility of systemic lupus erythematosus and rheumatoid arthritis in a Chinese han population","volume":"77","author":"Tang","year":"2016","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0100","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1080\/08916930701510848","article-title":"PTPN22: its role in SLE and autoimmunity","volume":"40","author":"Chung","year":"2007","journal-title":"Autoimmunity"},{"key":"10.1016\/j.bbadis.2026.168274_bb0105","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1136\/ard.2009.115535","article-title":"A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus","volume":"69","author":"Svenungsson","year":"2010","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0110","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0084450","article-title":"Association of STAT4 polymorphism with severe renal insufficiency in lupus nephritis","volume":"8","author":"Bolin","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2026.168274_bb0115","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000084","article-title":"Specificity of the STAT4 genetic association for severe disease manifestations of systemic lupus erythematosus","volume":"4","author":"Taylor","year":"2008","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0120","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1136\/annrheumdis-2017-212794","article-title":"The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-\u03b3 production in T cells from patients with SLE","volume":"77","author":"Hagberg","year":"2018","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0125","doi-asserted-by":"crossref","first-page":"60933","DOI":"10.18632\/oncotarget.17458","article-title":"Association of STAT4 and PTPN22 polymorphisms and their interactions with type-1 autoimmune hepatitis susceptibility in Chinese Han children","volume":"8","author":"Li","year":"2017","journal-title":"Oncotarget"},{"key":"10.1016\/j.bbadis.2026.168274_bb0130","doi-asserted-by":"crossref","first-page":"7925","DOI":"10.1038\/s41598-019-44524-5","article-title":"Role of deleterious single nucleotide variants in the coding regions of TNFAIP3 for Japanese autoimmune hepatitis with cirrhosis","volume":"9","author":"Higuchi","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2026.168274_bb0135","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.1016\/j.jhep.2023.09.028","article-title":"Deleterious variants in TNFAIP3 are associated with type II and seronegative pediatric autoimmune hepatitis","volume":"80","author":"Pandurangi","year":"2024","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.humimm.2025.111288","article-title":"Association of TNFAIP3 expression and gene polymorphisms with systemic lupus erythematosus susceptibility in the Chinese han population","volume":"86","author":"Yang","year":"2025","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0145","doi-asserted-by":"crossref","first-page":"1105","DOI":"10.1089\/gtmb.2012.0096","article-title":"Associations between TNFAIP3 gene polymorphisms and systemic lupus erythematosus: a meta-analysis","volume":"16","author":"Lee","year":"2012","journal-title":"Genet. Test. Mol. Biomarkers"},{"key":"10.1016\/j.bbadis.2026.168274_bb0150","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.bcp.2009.02.009","article-title":"ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling","volume":"78","author":"Verstrepen","year":"2009","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0155","doi-asserted-by":"crossref","first-page":"R174","DOI":"10.1186\/ar3134","article-title":"Association of TNFAIP3 interacting protein 1, TNIP1 with systemic lupus erythematosus in a Japanese population: a case-control association study","volume":"12","author":"Kawasaki","year":"2010","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0160","doi-asserted-by":"crossref","first-page":"R186","DOI":"10.1186\/ar3514","article-title":"Replicated associations of TNFAIP3, TNIP1 and ETS1 with systemic lupus erythematosus in a southwestern Chinese population","volume":"13","author":"Zhong","year":"2011","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0165","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1038\/ng.468","article-title":"A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus","volume":"41","author":"Gateva","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0170","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/ng.311","article-title":"Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways","volume":"41","author":"Nair","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0175","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1038\/s10038-018-0440-0","article-title":"Association of a single nucleotide polymorphism in TNIP1 with type-1 autoimmune hepatitis in the Japanese population","volume":"63","author":"Oka","year":"2018","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0180","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.gendis.2017.12.006","article-title":"Cytotoxic T lymphocyte antigen-4 gene polymorphisms and susceptibility to type 1 autoimmune hepatitis in the Tunisian population","volume":"5","author":"Chaouali","year":"2018","journal-title":"Genes Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0185","article-title":"HLA and non-HLA gene polymorphisms in autoimmune hepatitis patients of north Indian adults","volume":"13","author":"Ahuja","year":"2022","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0190","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1136\/ard.58.3.193","article-title":"The a-G polymorphism in exon 1 of the CTLA-4 gene is not associated with systemic lupus erythematosus","volume":"58","author":"Heward","year":"1999","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0195","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1136\/jclinpath-2019-206013","article-title":"Role of CTLA4 A49G polymorphism in systemic lupus erythematosus and its geographical distribution","volume":"72","author":"Kailashiya","year":"2019","journal-title":"J. Clin. Pathol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0200","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1038\/jhg.2017.74","article-title":"Association of autoimmune hepatitis with src homology 2 adaptor protein 3 gene polymorphisms in Japanese patients","volume":"62","author":"Umemura","year":"2017","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0205","doi-asserted-by":"crossref","first-page":"1457","DOI":"10.1038\/ng.3434","article-title":"Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus","volume":"47","author":"Bentham","year":"2015","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0210","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1000696","article-title":"High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions","volume":"5","author":"Barcellos","year":"2009","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.0030192","article-title":"Identification of two independent risk factors for lupus within the MHC in United Kingdom families","volume":"3","author":"Fernando","year":"2007","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0220","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.jaut.2016.06.017","article-title":"A child\u2019s HLA-DRB1 genotype increases maternal risk of systemic lupus erythematosus","volume":"74","author":"Cruz","year":"2016","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0225","doi-asserted-by":"crossref","first-page":"9916","DOI":"10.1038\/s41598-022-14116-x","article-title":"Predisposition of HLA-DRB1*04:01\/*15 heterozygous genotypes to Japanese mixed connective tissue disease","volume":"12","author":"Oka","year":"2022","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbadis.2026.168274_bb0230","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/sj.gene.6364252","article-title":"The R620W C\/T polymorphism of the gene PTPN22 is associated with SLE independently of the association of PDCD1","volume":"6","author":"Reddy","year":"2005","journal-title":"Genes Immun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0235","doi-asserted-by":"crossref","first-page":"3349","DOI":"10.2147\/JIR.S309008","article-title":"Genetic polymorphisms in genes involved in the type I interferon system (IFIH1\/MDA-5, TNFAIP3\/A20, and STAT4): association with SLE Risk in Egyptian children and adolescents","volume":"14","author":"Zedan","year":"2021","journal-title":"J. Inflamm. Res."},{"key":"10.1016\/j.bbadis.2026.168274_bb0240","first-page":"10","article-title":"Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese","author":"W","year":"2009","journal-title":"Genes Immun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0245","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0111991","article-title":"A multilocus genetic study in a cohort of Italian SLE patients confirms the association with STAT4 gene and describes a new association with HCP5 gene","volume":"9","author":"Ciccacci","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2026.168274_bb0250","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0071382","article-title":"Association of STAT4 polymorphisms with susceptibility to type-1 autoimmune hepatitis in the Japanese population","volume":"8","author":"Migita","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2026.168274_bb0255","doi-asserted-by":"crossref","first-page":"570","DOI":"10.46497\/ArchRheumatol.2022.8769","article-title":"Association of <em>TNFAIP3<\/em> gene polymorphism (<em>rs5029939<\/em>) with susceptibility and clinical phenotype of systemic lupus erythematosus","volume":"36","author":"Gaballah","year":"2021","journal-title":"Arch. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0260","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1038\/ejhg.2012.277","article-title":"Genes identified in Asian SLE GWASs are also associated with SLE in Caucasian populations","volume":"21","author":"Wang","year":"2013","journal-title":"Eur. J. Hum. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0265","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1038\/ng.472","article-title":"Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus","volume":"41","author":"Han","year":"2009","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbadis.2026.168274_bb0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.autrev.2024.103648","article-title":"Immunopathogenesis of systemic lupus erythematosus: an update","volume":"23","author":"Arnaud","year":"2024","journal-title":"Autoimmun. Rev."},{"key":"10.1016\/j.bbadis.2026.168274_bb0275","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1038\/73152","article-title":"Disruption of positive selection of thymocytes causes autoimmunity","volume":"6","author":"Kretz-Rommel","year":"2000","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0280","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/0092-8674(87)90568-X","volume":"49","author":"Kappler","year":"1987","journal-title":"Cell"},{"key":"10.1016\/j.bbadis.2026.168274_bb0285","doi-asserted-by":"crossref","first-page":"703","DOI":"10.1084\/jem.20042251","article-title":"Defective B cell tolerance checkpoints in systemic lupus erythematosus","volume":"201","author":"Yurasov","year":"2005","journal-title":"J. Exp. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0290","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.coi.2008.09.001","article-title":"B-cell tolerance checkpoints in health and autoimmunity","volume":"20","author":"Meffre","year":"2008","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0295","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1159\/000444471","article-title":"The pathogenesis of autoimmune liver disease","volume":"34","author":"Arndtz","year":"2016","journal-title":"Dig. Dis. (Basel Switz)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0300","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1007\/s00281-022-00952-6","article-title":"Tolerance and autoimmunity in the liver","volume":"44","author":"Schramm","year":"2022","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0305","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1172\/JCI65414","article-title":"Medullary thymic epithelial cell depletion leads to autoimmune hepatitis","volume":"123","author":"Bonito","year":"2013","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2026.168274_bb0310","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1002\/hep.27639","article-title":"Autoimmune hepatitis in a murine autoimmune polyendocrine syndrome type 1 model is directed against multiple autoantigens","volume":"61","author":"Hardtke-Wolenski","year":"2015","journal-title":"Hepatol. (Baltim Md.)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0315","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1093\/intimm\/dxn044","article-title":"Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE)","volume":"20","author":"Bonelli","year":"2008","journal-title":"Int. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0320","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.jaut.2006.06.005","article-title":"Regulatory T cells in patients with systemic lupus erythematosus","volume":"27","author":"Alvarado-S\u00e1nchez","year":"2006","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2021.102619","article-title":"Regulatory T cells in autoimmune hepatitis: an updated overview","volume":"119","author":"Longhi","year":"2021","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0330","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S1471-4906(01)01888-9","article-title":"PD-1: an inhibitory immunoreceptor involved in peripheral tolerance","volume":"22","author":"Nishimura","year":"2001","journal-title":"Trends Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0335","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1007\/s10875-006-9048-9","article-title":"Programmed death-1 gene polymorphisms in patients with systemic lupus erythematosus in Taiwan","volume":"26","author":"Wang","year":"2006","journal-title":"J. Clin. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0340","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1002\/art.24227","article-title":"Genetic, immunologic, and immunohistochemical analysis of the programmed death 1\/programmed death ligand 1 pathway in human systemic lupus erythematosus","volume":"60","author":"Bertsias","year":"2009","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbadis.2026.168274_bb0345","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1038\/nri727","article-title":"The B7-CD28 superfamily","volume":"2","author":"Sharpe","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0350","doi-asserted-by":"crossref","first-page":"256","DOI":"10.5114\/ceh.2019.87642","article-title":"Hepatic expression of programmed death-1 (PD-1) and its ligand, PD-L1, in children with autoimmune hepatitis: relation to treatment response","volume":"5","author":"Agina","year":"2019","journal-title":"Clin. Exp. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0355","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1111\/j.1572-0241.2006.00948.x","article-title":"Expression of PD-1, PD-L1, and PD-L2 in the liver in autoimmune liver diseases","volume":"102","author":"Mataki","year":"2007","journal-title":"Am. J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0360","doi-asserted-by":"crossref","first-page":"232","DOI":"10.2174\/1386207322666190402160455","article-title":"Expression and significance of Th17 cells and related factors in patients with autoimmune hepatitis","volume":"22","author":"An","year":"2019","journal-title":"CCHTS"},{"key":"10.1016\/j.bbadis.2026.168274_bb0365","doi-asserted-by":"crossref","first-page":"1472","DOI":"10.1002\/art.24499","article-title":"Th17 and natural treg cell population dynamics in systemic lupus erythematosus","volume":"60","author":"Yang","year":"2009","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbadis.2026.168274_bb0370","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/BOR.0b013e32833c62b0","article-title":"Interleukin-17-producing T cells in lupus","volume":"22","author":"Crisp\u00edn","year":"2010","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0375","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.clim.2008.01.019","article-title":"Hyperproduction of IL-23 and IL-17 in patients with systemic lupus erythematosus: implications for Th17-mediated inflammation in auto-immunity","volume":"127","author":"Wong","year":"2008","journal-title":"Clin. Immunol. (Orlando Fla,)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0380","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1177\/0961203310389100","article-title":"IL-17-producing T cells in lupus nephritis","volume":"20","author":"Apostolidis","year":"2011","journal-title":"Lupus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0385","doi-asserted-by":"crossref","DOI":"10.1155\/2012\/823085","article-title":"Balance between regulatory T and Th17 cells in systemic lupus erythematosus: the old and the new","volume":"2012","author":"Alunno","year":"2012","journal-title":"Clin. Dev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0390","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1177\/0961203312457718","article-title":"The potential role of Th17 cells and Th17-related cytokines in the pathogenesis of lupus nephritis","volume":"21","author":"Chen","year":"2012","journal-title":"Lupus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0395","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1080\/1744666X.2019.1593141","article-title":"The role of IL-17 in systemic lupus erythematosus and its potential as a therapeutic target","volume":"15","author":"Koga","year":"2019","journal-title":"Expert Rev. Clin. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0400","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.clim.2014.05.004","article-title":"Emerging role of IL-17 and Th17 cells in systemic lupus erythematosus","volume":"154","author":"Martin","year":"2014","journal-title":"Clin. Immunol. (Orlando Fla)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0405","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1002\/hep.26583","article-title":"Dysfunctional CD39(POS) regulatory T cells and aberrant control of T-helper type 17 cells in autoimmune hepatitis","volume":"59","author":"Grant","year":"2014","journal-title":"Hepatol. (Baltim Md)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0410","article-title":"Interleukin-17 contributes to the pathogenesis of autoimmune hepatitis through inducing hepatic interleukin-6 expression","volume":"6","author":"Zhao","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbadis.2026.168274_bb0415","doi-asserted-by":"crossref","first-page":"1835","DOI":"10.4049\/jimmunol.1203013","article-title":"IL-17A plays a critical role in the pathogenesis of liver fibrosis through hepatic stellate cell activation","volume":"191","author":"Tan","year":"2013","journal-title":"J. Immunol. (Baltim Md: 1950)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0420","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/607073","article-title":"T helper 17 cells in autoimmune liver diseases","volume":"2013","author":"Abe","year":"2013","journal-title":"Clin. Dev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0425","doi-asserted-by":"crossref","first-page":"1406","DOI":"10.1002\/2211-5463.13148","article-title":"Tim-3 suppresses autoimmune hepatitis via the p38\/MKP-1 pathway in Th17 cells","volume":"11","author":"Wu","year":"2021","journal-title":"FEBS Open Bio"},{"key":"10.1016\/j.bbadis.2026.168274_bb0430","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1111\/j.0300-9475.2004.01370.x","article-title":"Decreased CD4+CD25+ T cells in peripheral blood of patients with systemic lupus erythematosus","volume":"59","author":"Liu","year":"2004","journal-title":"Scand. J. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0435","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1186\/1471-2172-10-5","article-title":"Low frequency of CD4+CD25+ Treg in SLE patients: a heritable trait associated with CTLA4 and TGFbeta gene variants","volume":"10","author":"Barreto","year":"2009","journal-title":"BMC Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0440","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1038\/nri3823","article-title":"The promise of low-dose interleukin-2 therapy for autoimmune and inflammatory diseases","volume":"15","author":"Klatzmann","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0445","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.jhep.2004.03.008","article-title":"Impairment of CD4(+)CD25(+) regulatory T-cells in autoimmune liver disease","volume":"41","author":"Longhi","year":"2004","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0450","doi-asserted-by":"crossref","first-page":"4484","DOI":"10.4049\/jimmunol.176.7.4484","article-title":"Functional study of CD4+CD25+ regulatory T cells in health and autoimmune hepatitis","volume":"176","author":"Longhi","year":"2006","journal-title":"J. Immunol. (Baltim Md,: 1950)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0455","doi-asserted-by":"crossref","first-page":"7163","DOI":"10.7150\/thno.44960","article-title":"Kupffer cells promote T-cell hepatitis by producing CXCL10 and limiting liver sinusoidal endothelial cell permeability","volume":"10","author":"Dai","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.bbadis.2026.168274_bb0460","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.4049\/jimmunol.0901216","article-title":"Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver","volume":"184","author":"Oo","year":"2010","journal-title":"J. Immunol. (Baltim MD: 1950)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0465","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1002\/hep.31739","article-title":"The clinical significance of hepatic CD69+ CD103+ CD8+ resident-memory T cells in autoimmune hepatitis","volume":"74","author":"You","year":"2021","journal-title":"Hepatol (Baltim Md)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0470","doi-asserted-by":"crossref","first-page":"1738","DOI":"10.1007\/s10495-024-01970-5","article-title":"IRG1\/itaconate inhibits proliferation and promotes apoptosis of CD69+CD103+CD8+ tissue-resident memory T cells in autoimmune hepatitis by regulating the JAK3\/STAT3\/P53 signalling pathway","volume":"29","author":"Zhou","year":"2024","journal-title":"Apoptosis: Int. J. Program Cell Death"},{"key":"10.1016\/j.bbadis.2026.168274_bb0475","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1177\/09612033211017218","article-title":"Expression pattern of tissue-resident memory T cells in cutaneous lupus erythematosus","volume":"30","author":"Gu","year":"2021","journal-title":"Lupus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0480","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2022.102811","article-title":"Skin CD4+ trm cells distinguish acute cutaneous lupus erythematosus from localized discoid lupus erythematosus\/subacute cutaneous lupus erythematosus and other skin diseases","volume":"128","author":"Zhao","year":"2022","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0485","doi-asserted-by":"crossref","DOI":"10.1126\/sciimmunol.aba4163","article-title":"Pathogen-induced tissue-resident memory TH17 (TRM17) cells amplify autoimmune kidney disease","volume":"5","author":"Krebs","year":"2020","journal-title":"Sci. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0490","doi-asserted-by":"crossref","first-page":"7712","DOI":"10.1038\/s41467-023-43427-4","article-title":"Stepwise differentiation of follicular helper T cells reveals distinct developmental and functional states","volume":"14","author":"Podest\u00e0","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0495","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.cellimm.2015.01.014","article-title":"Increased frequency of circulating follicular helper T cells in lupus patients is associated with autoantibody production in a CD40L-dependent manner","volume":"295","author":"Xu","year":"2015","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0500","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1002\/art.39020","article-title":"Circulating follicular helper-like T cells in systemic lupus erythematosus: association with disease activity","volume":"67","author":"Choi","year":"2015","journal-title":"Arthritis Rheumatol. (hob NJ)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0505","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2021.104420","article-title":"Distinct roles of ICOS and CD40L in human T-B cell adhesion and antibody production","volume":"368","author":"Liu","year":"2021","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0510","doi-asserted-by":"crossref","DOI":"10.1016\/j.humimm.2025.111258","article-title":"The imbalance of follicular helper T cells and follicular regulatory T cells is involved in renal injury in active lupus nephritis","volume":"86","author":"Jiang","year":"2025","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0515","doi-asserted-by":"crossref","first-page":"2063","DOI":"10.1172\/JCI118643","article-title":"Hyperexpression of CD40 ligand by B and T cells in human lupus and its role in pathogenic autoantibody production","volume":"97","author":"Desai-Mehta","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2026.168274_bb0520","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1172\/JCI118855","article-title":"Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes","volume":"98","author":"Koshy","year":"1996","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbadis.2026.168274_bb0525","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41392-025-02168-0","article-title":"Systemic lupus erythematosus: updated insights on the pathogenesis, diagnosis, prevention and therapeutics","volume":"10","author":"Dai","year":"2025","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0530","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1111\/liv.12245","article-title":"Tfh and plasma cells are correlated with hypergammaglobulinaemia in patients with autoimmune hepatitis","volume":"34","author":"Ma","year":"2014","journal-title":"Liver Int: Off J Int Assoc Study Liver"},{"issue":"1322\u20131333","key":"10.1016\/j.bbadis.2026.168274_bb0535","first-page":"e1","article-title":"Dysregulated generation of follicular helper T cells in the spleen triggers fatal autoimmune hepatitis in mice","volume":"140","author":"Aoki","year":"2011","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbadis.2026.168274_bb0540","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.jmii.2019.06.007","article-title":"Exploration the significance of tfh and related molecules on C57BL\/6 mice model of experimental autoimmune hepatitis","volume":"54","author":"Ma","year":"2021","journal-title":"J Microbiol Immunol Infect = Wei Mian Yu Gan Ran Za Zhi"},{"key":"10.1016\/j.bbadis.2026.168274_bb0545","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1186\/s40064-016-2512-y","article-title":"Interleukin-21 plays a critical role in the pathogenesis and severity of type I autoimmune hepatitis","volume":"5","author":"Abe","year":"2016","journal-title":"Springerplus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0550","doi-asserted-by":"crossref","first-page":"3948","DOI":"10.1111\/jcmm.14997","article-title":"Dysregulated TFR and TFH cells correlate with B-cell differentiation and antibody production in autoimmune hepatitis","volume":"24","author":"Liang","year":"2020","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0555","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.immuni.2007.12.004","article-title":"Sites and stages of autoreactive B cell activation and regulation","volume":"28","author":"Shlomchik","year":"2008","journal-title":"Immunity"},{"key":"10.1016\/j.bbadis.2026.168274_bb0560","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1038\/ni0901-764","article-title":"Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity","volume":"2","author":"Lipsky","year":"2001","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0565","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1038\/nrneph.2015.33","article-title":"Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis","volume":"11","author":"Mohan","year":"2015","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0570","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.952304","article-title":"B cells in systemic lupus erythematosus: targets of new therapies and surveillance tools","volume":"9","author":"Parodis","year":"2022","journal-title":"Front. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0575","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1111\/imr.12810","article-title":"BAFF inhibition in SLE-is tolerance restored?","volume":"292","author":"Jackson","year":"2019","journal-title":"Immunol. Rev."},{"key":"10.1016\/j.bbadis.2026.168274_bb0580","doi-asserted-by":"crossref","first-page":"R6","DOI":"10.1186\/ar1855","article-title":"B lymphocyte stimulator (BLyS) isoforms in systemic lupus erythematosus: disease activity correlates better with blood leukocyte BLyS mRNA levels than with plasma BLyS protein levels","volume":"8","author":"Collins","year":"2006","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0585","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1038\/nri3795","article-title":"The generation of antibody-secreting plasma cells","volume":"15","author":"Nutt","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0590","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1186\/s13075-015-0551-3","article-title":"Long-lived plasma cells are early and constantly generated in New Zealand black\/New Zealand white F1 mice and their therapeutic depletion requires a combined targeting of autoreactive plasma cells and their precursors","volume":"17","author":"Taddeo","year":"2015","journal-title":"Arthritis Res. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0595","article-title":"Research progress on regulatory B cells in systemic lupus erythematosus","volume":"2019","author":"Wang","year":"2019","journal-title":"Biomed. Res. Int."},{"key":"10.1016\/j.bbadis.2026.168274_bb0600","doi-asserted-by":"crossref","first-page":"2110","DOI":"10.4049\/jimmunol.1900488","article-title":"CD24hiCD38hi and CD24hiCD27+ human regulatory B cells display common and distinct functional characteristics","volume":"203","author":"Hasan","year":"2019","journal-title":"J. Immunol. (Baltim MD,: 1950)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0605","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1016\/j.humimm.2007.03.010","article-title":"Elevated serum BAFF levels in patients with autoimmune hepatitis","volume":"68","author":"Migita","year":"2007","journal-title":"Hum. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0610","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000003194","article-title":"B-cell activating factor belonging to the tumor necrosis factor family and interferon-\u03b3-inducible protein-10 in autoimmune hepatitis","volume":"95","author":"Nishikawa","year":"2016","journal-title":"Medicine (Baltimore)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0615","article-title":"B-cell activating factor and IL-21 levels predict treatment response in autoimmune hepatitis","volume":"4","author":"Biewenga","year":"2022","journal-title":"JHEP Rep: Innov. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0620","article-title":"IL-15-producing splenic B cells play pathogenic roles in the development of autoimmune hepatitis","volume":"5","author":"Fujimori","year":"2023","journal-title":"JHEP Rep: Innov. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0625","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1055\/s-0039-1688751","article-title":"The contribution of B cells in autoimmune liver diseases","volume":"39","author":"Taylor","year":"2019","journal-title":"Semin. Liver Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0630","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1007\/s00281-022-00937-5","article-title":"B cells in autoimmune hepatitis: bystanders or central players?","volume":"44","author":"Schulthei\u00df","year":"2022","journal-title":"Semin. Immunopathol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0635","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1007\/s12016-021-08888-9","article-title":"Autoimmune hepatitis: serum autoantibodies in clinical practice","volume":"63","author":"Terziroli Beretta-Piccoli","year":"2022","journal-title":"Clin. Rev. Allergy Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0640","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1093208","article-title":"Toll-like receptors 7 and 9 regulate the proliferation and differentiation of B cells in systemic lupus erythematosus","volume":"14","author":"Wen","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0645","doi-asserted-by":"crossref","first-page":"1012","DOI":"10.1177\/0961203310371161","article-title":"The interferon-alpha signature of systemic lupus erythematosus","volume":"19","author":"Obermoser","year":"2010","journal-title":"Lupus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0650","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.coi.2020.10.014","article-title":"Type I interferon in the pathogenesis of systemic lupus erythematosus","volume":"67","author":"Postal","year":"2020","journal-title":"Curr. Opin. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0655","doi-asserted-by":"crossref","DOI":"10.7717\/peerj.14871","article-title":"The imbalance of liver resident macrophages polarization promotes chronic autoimmune hepatitis development in mice","volume":"11","author":"Chi","year":"2023","journal-title":"PeerJ"},{"key":"10.1016\/j.bbadis.2026.168274_bb0660","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2174\/1566524022666220106154111","article-title":"Cyclosporine ameliorates silica-induced autoimmune hepatitis in rat model by altering the expression of toll-like receptor-4, interleukin-2, and tumor necrosis factor-\u03b1","volume":"23","author":"Mohammed","year":"2023","journal-title":"Curr. Mol. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0665","doi-asserted-by":"crossref","first-page":"5988","DOI":"10.3748\/wjg.v29.i45.5988","article-title":"Pien tze huang alleviates concanavalin a-induced autoimmune hepatitis by regulating intestinal microbiota and memory regulatory T cells","volume":"29","author":"Zeng","year":"2023","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0670","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.molimm.2020.05.014","article-title":"Hepatocytes paradoxically affect intrahepatic IFN-\u03b3 production in autoimmune hepatitis due to gal-9 expression and TLR2\/4 ligand release","volume":"123","author":"Mo","year":"2020","journal-title":"Mol. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0675","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1038\/s41577-019-0165-0","article-title":"The NLRP3 inflammasome: molecular activation and regulation to therapeutics","volume":"19","author":"Swanson","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0680","doi-asserted-by":"crossref","first-page":"1840","DOI":"10.1002\/art.40166","article-title":"Enhanced inflammasome activity in systemic lupus erythematosus is mediated via type I interferon-induced up-regulation of interferon regulatory factor 1","volume":"69","author":"Liu","year":"2017","journal-title":"Arthritis Rheumatol. (hob NJ)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0685","doi-asserted-by":"crossref","first-page":"1636","DOI":"10.1002\/art.40155","article-title":"Podocyte activation of NLRP3 inflammasomes contributes to the development of proteinuria in lupus nephritis","volume":"69","author":"Fu","year":"2017","journal-title":"Arthritis Rheumatol. (hob NJ)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0690","doi-asserted-by":"crossref","first-page":"1139","DOI":"10.1186\/s12967-024-05951-9","article-title":"Novel approach to alleviate lupus nephritis: targeting the NLRP3 inflammasome in CD8+CD69+CD103+ TRM cells","volume":"22","author":"Lai","year":"2024","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0695","doi-asserted-by":"crossref","DOI":"10.1016\/j.jaut.2025.103411","article-title":"Neutrophil extracellular traps induce trophoblasts pyroptosis via enhancing NLRP3 lactylation in SLE pregnancies","volume":"153","author":"Hu","year":"2025","journal-title":"J. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0700","doi-asserted-by":"crossref","first-page":"758","DOI":"10.3389\/fimmu.2018.00758","article-title":"NOD-like receptor protein 3 inflammasome-dependent IL-1\u03b2 accelerated ConA-induced hepatitis","volume":"9","author":"Luan","year":"2018","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0705","doi-asserted-by":"crossref","first-page":"2677","DOI":"10.1002\/art.34473","article-title":"Derivation and validation of the systemic lupus international collaborating clinics classification criteria for systemic lupus erythematosus","volume":"64","author":"Petri","year":"2012","journal-title":"Arthritis Rheum."},{"key":"10.1016\/j.bbadis.2026.168274_bb0710","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1002\/art.40930","article-title":"2019 European League Against Rheumatism\/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus","volume":"71","author":"Aringer","year":"2019","journal-title":"Arthritis Rheumatol. (hob NJ)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0715","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.jped.2018.04.007","article-title":"Autoimmune hepatitis in 828 brazilian children and adolescents: clinical and laboratory findings, histological profile, treatments, and outcomes","volume":"95","author":"Porta","year":"2019","journal-title":"J. Pediatr."},{"key":"10.1016\/j.bbadis.2026.168274_bb0720","article-title":"The complement system in liver diseases: evidence-based approach and therapeutic options","volume":"2","author":"Lung","year":"2019","journal-title":"J. Transl. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0725","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41584-023-01071-8","article-title":"The gut microbiome in systemic lupus erythematosus: lessons from rheumatic fever","volume":"20","author":"Silverman","year":"2024","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0730","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01548-14","article-title":"Intestinal dysbiosis associated with systemic lupus erythematosus","volume":"5","author":"Hevia","year":"2014","journal-title":"Mbio"},{"key":"10.1016\/j.bbadis.2026.168274_bb0735","doi-asserted-by":"crossref","first-page":"7551","DOI":"10.1128\/AEM.02676-14","article-title":"Dynamics of gut microbiota in autoimmune lupus","volume":"80","author":"Zhang","year":"2014","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0740","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1186\/s13099-016-0146-9","article-title":"Alterations of the gut microbiome in chinese patients with systemic lupus erythematosus","volume":"8","author":"He","year":"2016","journal-title":"Gut Pathogens"},{"key":"10.1016\/j.bbadis.2026.168274_bb0745","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/art.41511","article-title":"An autoimmunogenic and proinflammatory profile defined by the gut microbiota of patients with untreated systemic lupus erythematosus","volume":"73","author":"Chen","year":"2021","journal-title":"Arthritis Rheumatol. (hob NJ)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0750","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1337223","article-title":"The significance of gut microbiota in the etiology of autoimmune hepatitis: a narrative review","volume":"14","author":"Sun","year":"2024","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0755","doi-asserted-by":"crossref","first-page":"71","DOI":"10.5387\/fms.2019-21","article-title":"Gut and oral microbiota in autoimmune liver disease","volume":"65","author":"Abe","year":"2020","journal-title":"Fukushima J. Med. Sci."},{"key":"10.1016\/j.bbadis.2026.168274_bb0760","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1136\/gutjnl-2018-317836","article-title":"Alterations of gut microbiome in autoimmune hepatitis","volume":"69","author":"Wei","year":"2020","journal-title":"Gut"},{"key":"10.1016\/j.bbadis.2026.168274_bb0765","first-page":"5153","article-title":"Abnormal intestinal permeability and microbiota in patients with autoimmune hepatitis","volume":"8","author":"Lin","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0770","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1111\/apt.15754","article-title":"A disease-specific decline of the relative abundance of bifidobacterium in patients with autoimmune hepatitis","volume":"51","author":"Liwinski","year":"2020","journal-title":"Aliment. Pharmacol. Ther."},{"key":"10.1016\/j.bbadis.2026.168274_bb0775","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.chom.2018.11.009","article-title":"A diet-sensitive commensal lactobacillus strain mediates TLR7-dependent systemic autoimmunity","volume":"25","author":"Zegarra-Ruiz","year":"2019","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbadis.2026.168274_bb0780","doi-asserted-by":"crossref","DOI":"10.1016\/j.cellimm.2022.104575","article-title":"Methyl butyrate attenuates concanavalin a-induced autoimmune hepatitis by inhibiting Th1-cell activation and homing to the liver","volume":"378","author":"Yang","year":"2022","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0785","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1002\/hep4.1742","article-title":"Hepatic adenosine triphosphate reduction through the short-chain fatty acids-peroxisome proliferator-activated receptor \u03b3-uncoupling protein 2 axis alleviates immune-mediated acute hepatitis in inulin-supplemented mice","volume":"5","author":"Yamaguchi","year":"2021","journal-title":"Hepatol. Commun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0790","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.cellimm.2018.03.003","article-title":"High fiber dietary and sodium butyrate attenuate experimental autoimmune hepatitis through regulation of immune regulatory cells and intestinal barrier","volume":"328","author":"Hu","year":"2018","journal-title":"Cell. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0795","article-title":"Short-chain fatty acids from gut microbiota restore Th17\/treg balance in rheumatoid arthritis: mechanisms and therapeutic potential","volume":"11","author":"Pang","year":"2025","journal-title":"J. Transl. Autoimmun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0800","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/j.bbrc.2017.03.071","article-title":"Short-chain fatty acids, GPR41 and GPR43 ligands, inhibit TNF-\u03b1-induced MCP-1 expression by modulating p38 and JNK signaling pathways in human renal cortical epithelial cells","volume":"486","author":"Kobayashi","year":"2017","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbadis.2026.168274_bb0805","doi-asserted-by":"crossref","DOI":"10.1016\/j.clim.2024.110235","article-title":"Targeted metabolomics combined with machine learning to identify and validate new biomarkers for early SLE diagnosis and disease activity","volume":"264","author":"Liang","year":"2024","journal-title":"Clin. Immunol. (Orlando Fla,)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0810","doi-asserted-by":"crossref","first-page":"2138","DOI":"10.3389\/fimmu.2020.02138","article-title":"Fecal metabolites were altered, identified as biomarkers and correlated with disease activity in patients with systemic lupus erythematosus in a GC-MS-based metabolomics study","volume":"11","author":"Yan","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0815","doi-asserted-by":"crossref","first-page":"5764","DOI":"10.3748\/wjg.v28.i39.5764","article-title":"Serum metabolic profiling of targeted bile acids reveals potentially novel biomarkers for primary biliary cholangitis and autoimmune hepatitis","volume":"28","author":"Ma","year":"2022","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0820","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nrgastro.2017.119","article-title":"Bile acid-microbiota crosstalk in gastrointestinal inflammation and carcinogenesis","volume":"15","author":"Jia","year":"2018","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0825","doi-asserted-by":"crossref","DOI":"10.1177\/1178646919868978","article-title":"The plasma [kynurenine]\/[tryptophan] ratio and indoleamine 2,3-dioxygenase: time for appraisal","volume":"12","author":"Badawy","year":"2019","journal-title":"Int, J, Tryptophan Res: IJTR"},{"key":"10.1016\/j.bbadis.2026.168274_bb0830","doi-asserted-by":"crossref","DOI":"10.1155\/2020\/9706140","article-title":"Tryptophan metabolism, regulatory T cells, and inflammatory bowel disease: a mini review","volume":"2020","author":"Ding","year":"2020","journal-title":"Mediat. Inflamm."},{"key":"10.1016\/j.bbadis.2026.168274_bb0835","doi-asserted-by":"crossref","DOI":"10.1136\/lupus-2022-000808","article-title":"Associations between circulating interferon and kynurenine\/tryptophan pathway metabolites: support for a novel potential mechanism for cognitive dysfunction in SLE","volume":"9","author":"Anderson","year":"2022","journal-title":"Lupus Sci. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0840","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1007\/s12026-019-9068-1","article-title":"Tryptophan-kynurenine profile in pediatric autoimmune hepatitis","volume":"67","author":"Lytton","year":"2019","journal-title":"Immunol. Res."},{"key":"10.1016\/j.bbadis.2026.168274_bb0845","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1007\/s00018-014-1762-5","article-title":"Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling","volume":"72","author":"P\u0142\u00f3ciennikowska","year":"2015","journal-title":"Cell. Mol. Life Sci: CMLS"},{"key":"10.1016\/j.bbadis.2026.168274_bb0850","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1002\/acr2.11664","article-title":"Racial differences in plasma microbial translocation and plasma microbiome, implications in systemic lupus erythematosus disease pathogenesis","volume":"6","author":"Wen","year":"2024","journal-title":"ACR Open Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0855","doi-asserted-by":"crossref","DOI":"10.1002\/mco2.610","article-title":"Lipopolysaccharide released from gut activates pyroptosis of macrophages via caspase 11-gasdermin D pathway in systemic lupus erythematosus","volume":"5","author":"Xin","year":"2024","journal-title":"Medcomm"},{"key":"10.1016\/j.bbadis.2026.168274_bb0860","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1007\/s12072-010-9219-x","article-title":"The role of lipopolysaccharide\/toll-like receptor 4 signaling in chronic liver diseases","volume":"4","author":"Soares","year":"2010","journal-title":"Hepatol. Int."},{"key":"10.1016\/j.bbadis.2026.168274_bb0865","doi-asserted-by":"crossref","first-page":"S101","DOI":"10.1016\/j.jhep.2015.03.005","article-title":"Autoimmune hepatitis--update 2015","volume":"62","author":"Manns","year":"2015","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0870","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/j.bpg.2011.09.009","article-title":"Pathogenesis of autoimmune hepatitis","volume":"25","author":"Liberal","year":"2011","journal-title":"Best Pract. Res. Clin. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0875","doi-asserted-by":"crossref","first-page":"2111","DOI":"10.1056\/NEJMra1100359","article-title":"Systemic lupus erythematosus","volume":"365","author":"Tsokos","year":"2011","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0880","doi-asserted-by":"crossref","first-page":"929","DOI":"10.1056\/NEJMra071297","article-title":"Systemic lupus erythematosus","volume":"358","author":"Rahman","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0885","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1146\/annurev.immunol.021908.132629","article-title":"The liver as a lymphoid organ","volume":"27","author":"Crispe","year":"2009","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0890","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/cmi.2016.5","article-title":"Immunological functions of liver sinusoidal endothelial cells","volume":"13","author":"Knolle","year":"2016","journal-title":"Cell. Mol. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0895","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1097\/BOR.0b013e3283562c3e","article-title":"Type I IFN system in the development and manifestations of SLE","volume":"24","author":"Elkon","year":"2012","journal-title":"Curr. Opin. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0900","doi-asserted-by":"crossref","first-page":"5459","DOI":"10.4049\/jimmunol.1002795","article-title":"Type I interferon in the pathogenesis of lupus","volume":"192","author":"Crow","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0905","doi-asserted-by":"crossref","first-page":"1044","DOI":"10.1016\/j.jhep.2012.07.008","article-title":"CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver","volume":"57","author":"Oo","year":"2012","journal-title":"J. Hepatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0910","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nrrheum.2012.58","article-title":"Follicular helper T cells in immunity and systemic autoimmunity","volume":"8","author":"Craft","year":"2012","journal-title":"Nat. Rev. Rheumatol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0915","article-title":"Autoimmune hepatitis and systemic lupus erythematosus overlap syndrome: a case report and literature review","volume":"16","author":"Kheyami","year":"2024","journal-title":"Cureus"},{"key":"10.1016\/j.bbadis.2026.168274_bb0920","doi-asserted-by":"crossref","first-page":"12662","DOI":"10.3748\/wjg.v20.i35.12662","article-title":"Association of autoimmune hepatitis and systemic lupus erythematodes: a case series and review of the literature","volume":"20","author":"Beisel","year":"2014","journal-title":"World J. Gastroenterol."},{"issue":"Suppl. 2","key":"10.1016\/j.bbadis.2026.168274_bb0925","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1159\/000440707","article-title":"Association of extrahepatic manifestations with autoimmune hepatitis","volume":"33","author":"Wong","year":"2015","journal-title":"Dig. Dis. (Basel Switz)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0930","doi-asserted-by":"crossref","first-page":"1232","DOI":"10.1080\/00365520802130183","article-title":"Epidemiology and the initial presentation of autoimmune hepatitis in Sweden: a nationwide study","volume":"43","author":"Werner","year":"2008","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0935","doi-asserted-by":"crossref","first-page":"1862","DOI":"10.3748\/wjg.v11.i12.1862","article-title":"Genetic distinctions between autoimmune hepatitis in Italy and North America","volume":"11","author":"Muratori","year":"2005","journal-title":"World J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0940","first-page":"1945","article-title":"Clinical features of japanese elderly patients with type 1 autoimmune hepatitis","volume":"46","author":"Miyake","year":"2007","journal-title":"Intern. Med. (Tokyo Jpn)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0945","doi-asserted-by":"crossref","first-page":"732","DOI":"10.3109\/00365521.2011.558114","article-title":"Autoimmune liver disease in patients with systemic lupus erythematosus: a retrospective analysis of 147 cases","volume":"46","author":"Efe","year":"2011","journal-title":"Scand. J. Gastroenterol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0950","first-page":"258","article-title":"Autoimmune hepatitis accompanied by systemic lupus erythematosus","volume":"43","author":"Tojo","year":"2004","journal-title":"Intern. Med. (Tokyo Jpn)"},{"key":"10.1016\/j.bbadis.2026.168274_bb0955","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1136\/ard-2022-222501","article-title":"Low-dose interleukin-2 therapy in active systemic lupus erythematosus (LUPIL-2): a multicentre, double-blind, randomised and placebo-controlled phase II trial","volume":"81","author":"Humrich","year":"2022","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb0960","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1038\/nm.4148","article-title":"Low-dose interleukin-2 treatment selectively modulates CD4+ T cell subsets in patients with systemic lupus erythematosus","volume":"22","author":"He","year":"2016","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb0965","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/S0140-6736(10)61354-2","article-title":"Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial","volume":"377","author":"Navarra","year":"2011","journal-title":"Lancet"},{"key":"10.1016\/j.bbadis.2026.168274_bb0970","first-page":"11","article-title":"Changes in gut microbiota and systemic inflammation after synbiotic supplementation in patients with systemic lupus erythematosus: a randomized, double-blind, placebo-controlled trial","author":"A","year":"2022","journal-title":"Cells"},{"key":"10.1016\/j.bbadis.2026.168274_bb0975","first-page":"9","article-title":"Fecal microbiota transplantation regulates TFH\/TFR cell imbalance via TLR\/MyD88 pathway in experimental autoimmune hepatitis","author":"L","year":"2023","journal-title":"Heliyon"},{"key":"10.1016\/j.bbadis.2026.168274_bb0980","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.02288-17","article-title":"Gut microbiota in human systemic lupus erythematosus and a mouse model of lupus","volume":"84","author":"Luo","year":"2018","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0985","first-page":"11","article-title":"Microbiome and metabolome analyses reveal the disruption of lipid metabolism in systemic lupus erythematosus","author":"J","year":"2020","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0990","first-page":"10","article-title":"Fecal microbiomes distinguish patients with autoimmune hepatitis from healthy individuals","author":"J","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.bbadis.2026.168274_bb0995","first-page":"78","article-title":"Lupus nephritis is linked to disease-activity associated expansions and immunity to a gut commensal","author":"D","year":"2019","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb1000","first-page":"9","article-title":"Gut microbiota in systemic lupus erythematosus and correlation with diet and clinical manifestations","author":"X","year":"2022","journal-title":"Front. Med."},{"key":"10.1016\/j.bbadis.2026.168274_bb1005","doi-asserted-by":"crossref","first-page":"1575","DOI":"10.1136\/annrheumdis-2021-220687","article-title":"Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in japanese","volume":"80","author":"Tomofuji","year":"2021","journal-title":"Ann. Rheum. Dis."},{"key":"10.1016\/j.bbadis.2026.168274_bb1010","first-page":"8","article-title":"Autoimmune hepatitis: shifts in gut microbiota and metabolic pathways among egyptian patients","author":"Nm","year":"2020","journal-title":"Microorganisms"},{"key":"10.1016\/j.bbadis.2026.168274_bb1015","article-title":"Disordered intestinal microbes are associated with the activity of Systemic Lupus Erythematosus","volume":"133","author":"Y","year":"2019","journal-title":"Clin. Sci. (lond Engl\u00a0: 1979)"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443926001377?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0925443926001377?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T09:23:22Z","timestamp":1783157002000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0925443926001377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":203,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S0925443926001377"],"URL":"https:\/\/doi.org\/10.1016\/j.bbadis.2026.168274","relation":{},"ISSN":["0925-4439"],"issn-type":[{"value":"0925-4439","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Shared pathogenic mechanisms between systemic lupus erythematosus and autoimmune hepatitis: A unified view of autoimmune convergence","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbadis.2026.168274","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"168274"}}