{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T07:51:09Z","timestamp":1793087469396,"version":"4.5.0"},"reference-count":71,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Chang Gung Memorial Hospital Research Funding","award":["CMRPD1B0441-3"],"award-info":[{"award-number":["CMRPD1B0441-3"]}]},{"DOI":"10.13039\/501100001868","name":"National Science Council, Taiwan","doi-asserted-by":"crossref","award":["NSC-101-2320-B182-025-MY3"],"award-info":[{"award-number":["NSC-101-2320-B182-025-MY3"]}],"id":[{"id":"10.13039\/501100001868","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - General Subjects"],"published-print":{"date-parts":[[2014,1]]},"DOI":"10.1016\/j.bbagen.2013.08.008","type":"journal-article","created":{"date-parts":[[2013,8,17]],"date-time":"2013-08-17T06:18:43Z","timestamp":1376720323000},"page":"53-64","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"title":["Adaptive responses to glucose restriction enhance cell survival, antioxidant capability, and autophagy of the protozoan parasite Trichomonas vaginalis"],"prefix":"10.1016","volume":"1840","author":[{"given":"Kuo-Yang","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ywan Margaret","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Kai","family":"Fang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei-Hung","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Chieh","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chuen","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany E.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fu-Man","family":"Ku","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shih-Chieh","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rose","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petrus","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbagen.2013.08.008_bb0005","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.ymgme.2011.11.007","article-title":"Nutritional stress in eukaryotic cells: oxidative species and regulation of survival in time of scarceness","volume":"105","author":"Ferretti","year":"2011","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0010","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1126\/science.1172539","article-title":"Extending healthy life span\u2014from yeast to humans","volume":"328","author":"Fontana","year":"2010","journal-title":"Science"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0015","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.4161\/cc.8.8.8287","article-title":"A molecular mechanism of chronological aging in yeast","volume":"8","author":"Burtner","year":"2009","journal-title":"Cell Cycle"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0020","doi-asserted-by":"crossref","first-page":"1193","DOI":"10.1126\/science.1115535","article-title":"Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients","volume":"310","author":"Kaeberlein","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0025","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1007\/978-1-59745-361-5_8","article-title":"The chronological life span of Saccharomyces cerevisiae","volume":"371","author":"Fabrizio","year":"2007","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0030","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.semcdb.2010.03.009","article-title":"Regulation of macroautophagy in Saccharomyces cerevisiae","volume":"21","author":"Inoue","year":"2010","journal-title":"Semin. Cell Dev. Biol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0035","series-title":"Sexually Transmitted Diseases","first-page":"771","article-title":"Trichomonas vaginalis and trichomoniasis","author":"Hobbs","year":"2008"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0040","first-page":"430","article-title":"Trichomonas vaginalis in the prostate gland","volume":"110","author":"Gardner","year":"1986","journal-title":"Arch. Pathol. Lab. Med."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0045","doi-asserted-by":"crossref","first-page":"698","DOI":"10.1086\/511278","article-title":"Infection with Trichomonas vaginalis increases the risk of HIV-1 acquisition","volume":"195","author":"McClelland","year":"2007","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0050","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1002\/ijc.24144","article-title":"Trichomonosis and subsequent risk of prostate cancer in the Prostate Cancer Prevention Trial","volume":"124","author":"Sutcliffe","year":"2009","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0055","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1146\/annurev.mi.42.100188.002341","article-title":"Energy metabolism of protozoa without mitochondria","volume":"42","author":"Muller","year":"1988","journal-title":"Annu. Rev. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0060","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0166-6851(86)90142-8","article-title":"Anaerobic pyruvate metabolism of Tritrichomonas foetus and Trichomonas vaginalis hydrogenosomes","volume":"20","author":"Steinbuchel","year":"1986","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0065","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.molbiopara.2003.09.004","article-title":"Ambient glucose concentration and gene expression in Plasmodium falciparum","volume":"133","author":"Fang","year":"2004","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0070","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/j.1550-7408.2001.tb00411.x","article-title":"A role for a galactose lectin and its ligands during encystment of Entamoeba","volume":"48","author":"Eichinger","year":"2001","journal-title":"J. Eukaryot. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0075","doi-asserted-by":"crossref","first-page":"e1247","DOI":"10.1371\/journal.pntd.0001247","article-title":"Glucose starvation boosts Entamoeba histolytica virulence","volume":"5","author":"Tovy","year":"2011","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0080","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1111\/cmi.12036","article-title":"Identification of dihydropyrimidine dehydrogenase as a virulence factor essential for the survival of Entamoeba histolytica in glucose-poor environments","volume":"15","author":"Baumel-Alterzon","year":"2013","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0085","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1111\/j.1550-7408.1995.tb01579.x","article-title":"YI-S, a casein-free medium for axenic cultivation of Entamoeba histolytica, related Entamoeba, Giardia intestinalis and Trichomonas vaginalis","volume":"42","author":"Diamond","year":"1995","journal-title":"J. Eukaryot. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0090","doi-asserted-by":"crossref","first-page":"127","DOI":"10.4161\/auto.7.2.13310","article-title":"Autophagy in protists","volume":"7","author":"Duszenko","year":"2011","journal-title":"Autophagy"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0095","doi-asserted-by":"crossref","first-page":"11384","DOI":"10.1074\/jbc.M512307200","article-title":"Endosome sorting and autophagy are essential for differentiation and virulence of Leishmania major","volume":"281","author":"Besteiro","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0100","doi-asserted-by":"crossref","first-page":"3454","DOI":"10.1074\/jbc.M708474200","article-title":"Autophagy is involved in nutritional stress response and differentiation in Trypanosoma cruzi","volume":"283","author":"Alvarez","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0105","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1128\/IAI.00636-07","article-title":"Autophagy during proliferation and encystation in the protozoan parasite Entamoeba invadens","volume":"76","author":"Picazarri","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0110","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1099\/mic.0.033944-0","article-title":"Autophagy is involved in starvation response and cell death in Blastocystis","volume":"156","author":"Yin","year":"2010","journal-title":"Microbiology"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0115","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1111\/j.1462-5822.2012.01795.x","article-title":"A role of autophagy in Trypanosoma brucei cell death","volume":"14","author":"Li","year":"2012","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0120","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1462-5822.2011.01745.x","article-title":"Autophagy is a cell death mechanism in Toxoplasma gondii","volume":"14","author":"Ghosh","year":"2012","journal-title":"Cell. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0125","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/nmeth1156","article-title":"Next-generation sequencing transforms today's biology","volume":"5","author":"Schuster","year":"2008","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0130","doi-asserted-by":"crossref","first-page":"1683","DOI":"10.1007\/s00436-009-1616-5","article-title":"Malate dehydrogenase is negatively regulated by miR-1 in Trichomonas vaginalis","volume":"105","author":"Lin","year":"2009","journal-title":"Parasitol. Res."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0135","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1186\/1471-2164-12-600","article-title":"De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes","volume":"12","author":"Barrero","year":"2011","journal-title":"BMC Genomics"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0140","doi-asserted-by":"crossref","first-page":"D526","DOI":"10.1093\/nar\/gkn631","article-title":"GiardiaDB and TrichDB: integrated genomic resources for the eukaryotic protist pathogens Giardia lamblia and Trichomonas vaginalis","volume":"37","author":"Aurrecoechea","year":"2009","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0145","doi-asserted-by":"crossref","first-page":"D986","DOI":"10.1093\/nar\/gkq995","article-title":"The Autophagy Database: an all-inclusive information resource on autophagy that provides nourishment for research","volume":"39","author":"Homma","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0150","doi-asserted-by":"crossref","first-page":"3389","DOI":"10.1093\/nar\/25.17.3389","article-title":"Gapped BLAST and PSI-BLAST: a new generation of protein database search programs","volume":"25","author":"Altschul","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0155","doi-asserted-by":"crossref","first-page":"D225","DOI":"10.1093\/nar\/gkq1189","article-title":"CDD: a Conserved Domain Database for the functional annotation of proteins","volume":"39","author":"Marchler-Bauer","year":"2011","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0160","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1186\/1476-4598-10-72","article-title":"Selective anticancer activity of a hexapeptide with sequence homology to a non-kinase domain of Cyclin Dependent Kinase 4","volume":"10","author":"Warenius","year":"2011","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0165","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00418-011-0869-0","article-title":"Proteasome inhibition by quercetin triggers macroautophagy and blocks mTOR activity","volume":"137","author":"Klappan","year":"2012","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0170","doi-asserted-by":"crossref","first-page":"e27485","DOI":"10.1371\/journal.pone.0027485","article-title":"Autophagy in human embryonic stem cells","volume":"6","author":"Tra","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0175","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/cyto.a.20896","article-title":"Quantifying colocalization by correlation: the Pearson correlation coefficient is superior to the Mander's overlap coefficient","volume":"77","author":"Adler","year":"2010","journal-title":"Cytometry A"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0180","doi-asserted-by":"crossref","first-page":"3900","DOI":"10.1128\/IAI.00611-12","article-title":"Comparative transcriptomic and proteomic analyses of Trichomonas vaginalis following adherence to fibronectin","volume":"80","author":"Huang","year":"2012","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0185","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1097\/01.AOG.0000246800.38892.fc","article-title":"Glucose in vaginal secretions before and after oral glucose tolerance testing in women with and without recurrent vulvovaginal candidiasis","volume":"108","author":"Ehrstrom","year":"2006","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0190","doi-asserted-by":"crossref","first-page":"48","DOI":"10.4103\/0253-7184.55490","article-title":"Cytolytic vaginosis: a review","volume":"30","author":"Surexh","year":"2009","journal-title":"Indian J. Sex Transm. Dis."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0195","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1007\/s00018-007-6470-y","article-title":"Ruminations on dietary restriction and aging","volume":"64","author":"Kennedy","year":"2007","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0200","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/nature08981","article-title":"Lessons on longevity from budding yeast","volume":"464","author":"Kaeberlein","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0205","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1128\/CMR.17.4.783-793.2004","article-title":"Treatment of infections caused by metronidazole-resistant Trichomonas vaginalis","volume":"17","author":"Cudmore","year":"2004","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0210","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1093\/gbe\/evs078","article-title":"Transcriptomic Identification of iron-regulated and iron-independent gene copies within the heavily duplicated Trichomonas vaginalis genome","volume":"4","author":"Horvathova","year":"2012","journal-title":"Genome Biol. Evol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0215","doi-asserted-by":"crossref","first-page":"E3278","DOI":"10.1073\/pnas.1209823109","article-title":"Plasmodium falciparum responds to amino acid starvation by entering into a hibernatory state","volume":"109","author":"Babbitt","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0220","doi-asserted-by":"crossref","first-page":"15123","DOI":"10.1073\/pnas.1004432107","article-title":"Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity","volume":"107","author":"Mesquita","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0225","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/j.cmet.2007.08.011","article-title":"Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress","volume":"6","author":"Schulz","year":"2007","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0230","doi-asserted-by":"crossref","first-page":"E1089","DOI":"10.1073\/pnas.1101494108","article-title":"Survival of starving yeast is correlated with oxidative stress response and nonrespiratory mitochondrial function","volume":"108","author":"Petti","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0235","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1126\/science.1132894","article-title":"Draft genome sequence of the sexually transmitted pathogen Trichomonas vaginalis","volume":"315","author":"Carlton","year":"2007","journal-title":"Science"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0240","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1016\/j.ijpara.2011.10.001","article-title":"The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria, yet complex compared with mitosomes","volume":"41","author":"Schneider","year":"2011","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0245","doi-asserted-by":"crossref","first-page":"5249","DOI":"10.1074\/jbc.M304359200","article-title":"The amitochondriate eukaryote Trichomonas vaginalis contains a divergent thioredoxin-linked peroxiredoxin antioxidant system","volume":"279","author":"Coombs","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0250","doi-asserted-by":"crossref","first-page":"B109","DOI":"10.1093\/gerona\/57.3.B109","article-title":"Multiple stressors in Caenorhabditis elegans induce stress hormesis and extended longevity","volume":"57","author":"Cypser","year":"2002","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0255","first-page":"1","article-title":"The role of hormesis in life extension by dietary restriction","volume":"35","author":"Masoro","year":"2007","journal-title":"Interdiscip. Top. Gerontol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0260","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1111\/j.1749-6632.2001.tb05633.x","article-title":"Stress resistance by caloric restriction for longevity","volume":"928","author":"Yu","year":"2001","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0265","first-page":"125","article-title":"Inhibition of Candida albicans by Lactobacillus acidophilus: evidence for the involvement of a peroxidase system","volume":"80","author":"Fitzsimmons","year":"1994","journal-title":"Microbios"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0270","doi-asserted-by":"crossref","first-page":"7169","DOI":"10.1128\/IAI.70.12.7169-7171.2002","article-title":"Inhibition of Neisseria gonorrhoeae by Lactobacillus species that are commonly isolated from the female genital tract","volume":"70","author":"St Amant","year":"2002","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0275","doi-asserted-by":"crossref","first-page":"2703","DOI":"10.1128\/IAI.00157-09","article-title":"Glyceraldehyde-3-phosphate dehydrogenase is a surface-associated, fibronectin-binding protein of Trichomonas vaginalis","volume":"77","author":"Lama","year":"2009","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0280","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1128\/IAI.01352-07","article-title":"Immunogenic and plasminogen-binding surface-associated alpha-enolase of Trichomonas vaginalis","volume":"76","author":"Mundodi","year":"2008","journal-title":"Infect. Immun."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MMBR.62.1.1-34.1998","article-title":"Major facilitator superfamily","volume":"62","author":"Pao","year":"1998","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0290","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0166-6851(96)02616-3","article-title":"The contribution of the arginine dihydrolase pathway to energy metabolism by Trichomonas vaginalis","volume":"78","author":"Yarlett","year":"1996","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0295","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/0166-6851(86)90080-0","article-title":"Aminotransferase activities in Trichomonas vaginalis","volume":"21","author":"Lowe","year":"1986","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0300","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1016\/j.neuint.2011.03.024","article-title":"From pancreatic islets to central nervous system, the importance of glutamate dehydrogenase for the control of energy homeostasis","volume":"59","author":"Karaca","year":"2011","journal-title":"Neurochem. Int."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0305","first-page":"F493","article-title":"Newer aspects of glutamine\/glutamate metabolism: the role of acute pH changes","volume":"277","author":"Nissim","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0310","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.cell.2006.06.057","article-title":"SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells","volume":"126","author":"Haigis","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0315","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/j.molbiopara.2010.04.002","article-title":"Susceptibility of Plasmodium falciparum to glutamate dehydrogenase inhibitors\u2014a possible new antimalarial target","volume":"172","author":"Aparicio","year":"2010","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0320","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0248-4900(99)80039-2","article-title":"Hydrogenosome autophagy: an ultrastructural and cytochemical study","volume":"91","author":"Benchimol","year":"1999","journal-title":"Biol. Cell"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0325","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.molbiopara.2011.02.003","article-title":"Autophagy in parasitic protists: unique features and drug targets","volume":"177","author":"Brennand","year":"2011","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0330","series-title":"Anaerobic Parasitic Protozoa: Genomics and Molecular Biology","first-page":"45","article-title":"The genome of Trichomonas vaginalis","author":"Carlton","year":"2010"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0335","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1111\/j.1365-2958.2006.05274.x","article-title":"Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana","volume":"61","author":"Williams","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0340","doi-asserted-by":"crossref","first-page":"17636","DOI":"10.1074\/jbc.M212467200","article-title":"Macroautophagy is required for multicellular development of the social amoeba Dictyostelium discoideum","volume":"278","author":"Otto","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0345","doi-asserted-by":"crossref","first-page":"e1002416","DOI":"10.1371\/journal.ppat.1002416","article-title":"Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites","volume":"7","author":"Besteiro","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbagen.2013.08.008_bb0350","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.4161\/auto.21028","article-title":"A novel image-based cytometry method for autophagy detection in living cells","volume":"8","author":"Chan","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.bbagen.2013.08.008_bb0355","doi-asserted-by":"crossref","first-page":"3619","DOI":"10.1242\/jcs.114.20.3619","article-title":"A novel assay to study autophagy: regulation of autophagosome vacuole size by amino acid deprivation","volume":"114","author":"Munafo","year":"2001","journal-title":"J. Cell Sci."}],"container-title":["Biochimica et Biophysica Acta (BBA) - General Subjects"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304416513003528?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304416513003528?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T01:51:19Z","timestamp":1646358679000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304416513003528"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,1]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2014,1]]}},"alternative-id":["S0304416513003528"],"URL":"https:\/\/doi.org\/10.1016\/j.bbagen.2013.08.008","relation":{},"ISSN":["0304-4165"],"issn-type":[{"value":"0304-4165","type":"print"}],"subject":[],"published":{"date-parts":[[2014,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Adaptive responses to glucose restriction enhance cell survival, antioxidant capability, and autophagy of the protozoan parasite Trichomonas vaginalis","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - General Subjects","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbagen.2013.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}