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Interact."},{"issue":"4","key":"10.1016\/j.bbagen.2024.130559_bb0780","doi-asserted-by":"crossref","first-page":"405","DOI":"10.1097\/NEN.0b013e3181d709eb","article-title":"Curcumin labeling of neuronal fibrillar tau inclusions in human brain samples","volume":"69","author":"Mohorko","year":"2010","journal-title":"J. Neuropathol. Exp. 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Agric. Food Chem."},{"issue":"6","key":"10.1016\/j.bbagen.2024.130559_bb0800","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1021\/mp700113r","article-title":"Bioavailability of curcumin: problems and promises","volume":"4","author":"Anand","year":"2007","journal-title":"Mol. Pharm."},{"key":"10.1016\/j.bbagen.2024.130559_bb0850","doi-asserted-by":"crossref","DOI":"10.1016\/j.brainres.2019.146325","article-title":"Neuroprotective effects of curcumin lipid-core nanocapsules in a model Alzheimer\u2019s disease induced by \u03b2-amyloid 1-42 peptide in aged female mice","volume":"1721","author":"Giacomeli","year":"2019","journal-title":"Brain Res."},{"issue":"3","key":"10.1016\/j.bbagen.2024.130559_bb0855","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0032616","article-title":"Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer\u2019s disease","volume":"7","author":"Mathew","year":"2012","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bbagen.2024.130559_bb0835","doi-asserted-by":"crossref","first-page":"671","DOI":"10.3233\/JAD-190083","article-title":"Neuroprotective potential of curcumin-loaded nanostructured lipid carrier in an animal model of Alzheimer\u2019s disease: behavioral and biochemical evidence","volume":"69","author":"Sadegh Malvajerd","year":"2019","journal-title":"J. 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Sci."},{"issue":"1","key":"10.1016\/j.bbagen.2024.130559_bb0895","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1021\/nn405077y","article-title":"Curcumin-loaded nanoparticles potently induce adult neurogenesis and reverse cognitive deficits in Alzheimer\u2019s disease model via canonical Wnt\/\u03b2-catenin pathway","volume":"8","author":"Tiwari","year":"2014","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.bbagen.2024.130559_bb0900","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3233\/JAD-2012-112141","article-title":"Neuronal uptake and neuroprotective effect of curcumin-loaded PLGA nanoparticles on the human SK-N-SH cell line","volume":"30","author":"Doggui","year":"2012","journal-title":"J. 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