{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T17:41:37Z","timestamp":1774374097619,"version":"3.50.1"},"reference-count":40,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,1]],"date-time":"2025-07-01T00:00:00Z","timestamp":1751328000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - General Subjects"],"published-print":{"date-parts":[[2025,7]]},"DOI":"10.1016\/j.bbagen.2025.130821","type":"journal-article","created":{"date-parts":[[2025,5,16]],"date-time":"2025-05-16T23:12:03Z","timestamp":1747437123000},"page":"130821","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["SLAMF9 aggravates myocardial ischemia reperfusion injury through activating the hippo-yap pathway"],"prefix":"10.1016","volume":"1869","author":[{"given":"Tingting","family":"Liu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiuli","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhua","family":"Fu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Weili","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"9","key":"10.1016\/j.bbagen.2025.130821_bb0005","doi-asserted-by":"crossref","first-page":"e139","DOI":"10.1161\/CIR.0000000000000757","article-title":"Heart disease and stroke statistics-2020 update: a report from the American Heart Association","volume":"141","author":"Virani","year":"2020","journal-title":"Circulation"},{"issue":"8","key":"10.1016\/j.bbagen.2025.130821_bb0010","doi-asserted-by":"crossref","first-page":"e153","DOI":"10.1161\/CIR.0000000000001052","article-title":"Heart disease and stroke statistics-2022 update: a report from the American Heart Association","volume":"145","author":"Tsao","year":"2022","journal-title":"Circulation"},{"issue":"18","key":"10.1016\/j.bbagen.2025.130821_bb0015","doi-asserted-by":"crossref","first-page":"e891","DOI":"10.1161\/CIR.0000000000000670","article-title":"Contemporary diagnosis and management of patients with myocardial infarction in the absence of obstructive coronary artery disease: a scientific statement from the American Heart Association","volume":"139","author":"Tamis-Holland","year":"2019","journal-title":"Circulation"},{"key":"10.1016\/j.bbagen.2025.130821_bb0020","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.ijcard.2015.08.172","article-title":"Worldwide disparities in cardiovascular disease: challenges and solutions","volume":"202","author":"Okwuosa","year":"2016","journal-title":"Int. J. Cardiol."},{"issue":"23","key":"10.1016\/j.bbagen.2025.130821_bb0025","doi-asserted-by":"crossref","first-page":"24270","DOI":"10.18632\/aging.202143","article-title":"Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK\/NLRP3 inflammasome pathway","volume":"12","author":"Zhang","year":"2020","journal-title":"Aging"},{"issue":"10151","key":"10.1016\/j.bbagen.2025.130821_bb0030","doi-asserted-by":"crossref","first-page":"893","DOI":"10.1016\/S0140-6736(18)31996-2","article-title":"Diagnosing myocardial infarction: a highly sensitive issue","volume":"392","author":"Blankenberg","year":"2018","journal-title":"Lancet"},{"issue":"10052","key":"10.1016\/j.bbagen.2025.130821_bb0035","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S0140-6736(16)31739-1","article-title":"Deferred stenting in acute ST elevation myocardial infarction","volume":"388","author":"Isaaz","year":"2016","journal-title":"Lancet"},{"issue":"4","key":"10.1016\/j.bbagen.2025.130821_bb0040","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1089\/mab.2014.0010","article-title":"Development and characterization of domain-specific monoclonal antibodies produced against human SLAMF9","volume":"33","author":"Volkova","year":"2014","journal-title":"Monoclon. Antibodies Immunodiag. Immunother."},{"issue":"2","key":"10.1016\/j.bbagen.2025.130821_bb0045","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s00281-009-0193-0","article-title":"SLAM family receptors and the SLAM-associated protein (SAP) modulate T cell functions","volume":"32","author":"Detre","year":"2010","journal-title":"Semin. Immunopathol."},{"issue":"1","key":"10.1016\/j.bbagen.2025.130821_bb0050","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nri2456","article-title":"SLAM receptors and SAP influence lymphocyte interactions, development and function","volume":"9","author":"Schwartzberg","year":"2009","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbagen.2025.130821_bb0055","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/S0065-2776(08)00004-7","article-title":"The SLAM and SAP gene families control innate and adaptive immune responses","volume":"97","author":"Calpe","year":"2008","journal-title":"Adv. Immunol."},{"issue":"7","key":"10.1016\/j.bbagen.2025.130821_bb0060","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1016\/j.autrev.2018.01.018","article-title":"The SLAM family receptors: potential therapeutic targets for inflammatory and autoimmune diseases","volume":"17","author":"Dragovich","year":"2018","journal-title":"Autoimmun. Rev."},{"issue":"7","key":"10.1016\/j.bbagen.2025.130821_bb0065","first-page":"608","article-title":"Periplaneta americana extract promotes infectious diabetic ulcers wound healing by downregulation of LINC01133\/SLAMF9","volume":"22","author":"Yang","year":"2024","journal-title":"Chin. J. Nat. Med."},{"issue":"2","key":"10.1016\/j.bbagen.2025.130821_bb0070","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1038\/s41423-018-0191-z","article-title":"Combined deficiency of SLAMF8 and SLAMF9 prevents endotoxin-induced liver inflammation by downregulating TLR4 expression on macrophages","volume":"17","author":"Zeng","year":"2020","journal-title":"Cell. Mol. Immunol."},{"issue":"4","key":"10.1016\/j.bbagen.2025.130821_bb0075","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1111\/imm.13169","article-title":"Signalling lymphocyte activation molecule family member 9 is found on select subsets of antigen-presenting cells and promotes resistance to Salmonella infection","volume":"159","author":"Wilson","year":"2020","journal-title":"Immunology"},{"issue":"1","key":"10.1016\/j.bbagen.2025.130821_bb0080","first-page":"H233","article-title":"Resistin promotes cardiac homing of mesenchymal stem cells and functional recovery after myocardial ischemia-reperfusion via the ERK1\/2-MMP-9 pathway","volume":"316","author":"He","year":"2019","journal-title":"Am. J. Phys. Heart Circ. Phys."},{"issue":"3","key":"10.1016\/j.bbagen.2025.130821_bb0085","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1161\/CIRCRESAHA.113.300929","article-title":"Prolyl hydroxylase domain protein 2 silencing enhances the survival and paracrine function of transplanted adipose-derived stem cells in infarcted myocardium","volume":"113","author":"Wang","year":"2013","journal-title":"Circ. Res."},{"issue":"1","key":"10.1016\/j.bbagen.2025.130821_bb0090","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/s41590-018-0249-1","article-title":"DEL-1 promotes macrophage efferocytosis and clearance of inflammation","volume":"20","author":"Kourtzelis","year":"2019","journal-title":"Nat. Immunol."},{"key":"10.1016\/j.bbagen.2025.130821_bb0095","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1146\/annurev-immunol-030409-101302","article-title":"SLAM family receptors and SAP adaptors in immunity","volume":"29","author":"Cannons","year":"2011","journal-title":"Annu. Rev. Immunol."},{"issue":"10332","key":"10.1016\/j.bbagen.2025.130821_bb0100","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/S0140-6736(21)02391-6","article-title":"Acute coronary syndromes","volume":"399","author":"Bergmark","year":"2022","journal-title":"Lancet"},{"issue":"11","key":"10.1016\/j.bbagen.2025.130821_bb0105","first-page":"6279","article-title":"MicroRNA-147 inhibits myocardial inflammation and apoptosis following myocardial infarction via targeting HIPK2","volume":"24","author":"Wu","year":"2020","journal-title":"Eur. Rev. Med. Pharmacol. Sci."},{"issue":"3","key":"10.1016\/j.bbagen.2025.130821_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.xpro.2021.100772","article-title":"Preclinical model of type 1 diabetes and myocardial ischemia\/reperfusion injury in conscious rabbits-demonstration of cardioprotection with rapamycin","volume":"2","author":"Samidurai","year":"2021","journal-title":"STAR Protoc."},{"issue":"1","key":"10.1016\/j.bbagen.2025.130821_bb0115","article-title":"The prognostic and immune significance of SLAMF9 in pan-cancer and validation of its role in colorectal cancer","volume":"14","author":"Zhao","year":"2024","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.bbagen.2025.130821_bb0120","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1002\/cyto.a.24469","article-title":"A simplified method for separating renal MPCs using SLAMF9","volume":"99","author":"Mikulin","year":"2021","journal-title":"Cytomet. Part A"},{"key":"10.1016\/j.bbagen.2025.130821_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2023.175569","article-title":"Idebenone attenuates ferroptosis by inhibiting excessive autophagy via the ROS-AMPK-mTOR pathway to preserve cardiac function after myocardial infarction","volume":"943","author":"Li","year":"2023","journal-title":"Eur. J. Pharmacol."},{"issue":"7","key":"10.1016\/j.bbagen.2025.130821_bb0130","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.1161\/ATVBAHA.111.224915","article-title":"Mechanisms of cell death in heart disease","volume":"32","author":"Konstantinidis","year":"2012","journal-title":"Arterioscler. Thromb. Vasc. Biol."},{"key":"10.1016\/j.bbagen.2025.130821_bb0135","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1146\/annurev.pathmechdis.3.121806.151456","article-title":"The inflammatory response to cell death","volume":"3","author":"Rock","year":"2008","journal-title":"Annu. Rev. Pathol."},{"key":"10.1016\/j.bbagen.2025.130821_bb0140","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.pharmthera.2018.01.001","article-title":"Inflammation following acute myocardial infarction: multiple players, dynamic roles, and novel therapeutic opportunities","volume":"186","author":"Ong","year":"2018","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bbagen.2025.130821_bb0145","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.addr.2019.05.011","article-title":"Cardiac fibrosis - a short review of causes and therapeutic strategies","volume":"146","author":"Hinderer","year":"2019","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"7","key":"10.1016\/j.bbagen.2025.130821_bb0150","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/s41419-020-02777-3","article-title":"Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload","volume":"11","author":"Wang","year":"2020","journal-title":"Cell Death Dis."},{"issue":"1","key":"10.1016\/j.bbagen.2025.130821_bb0155","doi-asserted-by":"crossref","first-page":"4452","DOI":"10.1038\/s41467-021-24736-y","article-title":"S-nitrosylation-mediated coupling of G-protein alpha-2 with CXCR5 induces Hippo\/YAP-dependent diabetes-accelerated atherosclerosis","volume":"12","author":"Chao","year":"2021","journal-title":"Nat. Commun."},{"issue":"8","key":"10.1016\/j.bbagen.2025.130821_bb0160","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1161\/CIRCRESAHA.116.303311","article-title":"The hippo pathway in heart development, regeneration, and diseases","volume":"116","author":"Zhou","year":"2015","journal-title":"Circ. Res."},{"issue":"23","key":"10.1016\/j.bbagen.2025.130821_bb0165","doi-asserted-by":"crossref","first-page":"4683","DOI":"10.1242\/dev.102798","article-title":"Hippo signaling impedes adult heart regeneration","volume":"140","author":"Heallen","year":"2013","journal-title":"Development (Cambridge, England)"},{"issue":"5","key":"10.1016\/j.bbagen.2025.130821_bb0170","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1007\/s10863-021-09910-7","article-title":"FoxO4 negatively modulates USP10 transcription to aggravate the apoptosis and oxidative stress of hypoxia\/reoxygenation-induced cardiomyocytes by regulating the Hippo\/YAP pathway","volume":"53","author":"Huang","year":"2021","journal-title":"J. Bioenerg. Biomembr."},{"issue":"3","key":"10.1016\/j.bbagen.2025.130821_bb0175","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/10799893.2020.1726954","article-title":"MST1-Hippo pathway regulates inflammation response following myocardial infarction through inhibiting HO-1 signaling pathway","volume":"40","author":"Tian","year":"2020","journal-title":"J. Recept. Signal Transduct. Res."},{"issue":"5","key":"10.1016\/j.bbagen.2025.130821_bb0180","doi-asserted-by":"crossref","DOI":"10.1111\/cpr.13221","article-title":"FGF6 promotes cardiac repair after myocardial infarction by inhibiting the Hippo pathway","volume":"55","author":"Hu","year":"2022","journal-title":"Cell Prolif."},{"key":"10.1016\/j.bbagen.2025.130821_bb0185","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2024.1463465","article-title":"Lats-IN-1 protects cardiac function and promotes regeneration after myocardial infarction by targeting the hippo pathway","volume":"15","author":"Shen","year":"2024","journal-title":"Front. Pharmacol."},{"issue":"10","key":"10.1016\/j.bbagen.2025.130821_bb0190","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1038\/s41419-018-1011-1","article-title":"The novel immunoglobulin super family receptor SLAMF9 identified in TAM of murine and human melanoma influences pro-inflammatory cytokine secretion and migration","volume":"9","author":"Dollt","year":"2018","journal-title":"Cell Death Dis."},{"issue":"6","key":"10.1016\/j.bbagen.2025.130821_bb0195","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/jop.12317","article-title":"LATS2 induced by TNF-alpha and inhibited cell proliferation and invasion by phosphorylating YAP in oral squamous cell carcinoma","volume":"44","author":"Dong","year":"2015","journal-title":"J. Oral Pathol. Med."},{"issue":"9","key":"10.1016\/j.bbagen.2025.130821_bb0200","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20092346","article-title":"The cross-talk between the TNF-\u03b1 and RASSF-hippo signalling pathways","volume":"20","author":"Oceandy","year":"2019","journal-title":"Int. J. Mol. Sci."}],"container-title":["Biochimica et Biophysica Acta (BBA) - General Subjects"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304416525000662?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0304416525000662?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T00:02:35Z","timestamp":1750204955000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0304416525000662"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":40,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,7]]}},"alternative-id":["S0304416525000662"],"URL":"https:\/\/doi.org\/10.1016\/j.bbagen.2025.130821","relation":{},"ISSN":["0304-4165"],"issn-type":[{"value":"0304-4165","type":"print"}],"subject":[],"published":{"date-parts":[[2025,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SLAMF9 aggravates myocardial ischemia reperfusion injury through activating the hippo-yap pathway","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - General Subjects","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbagen.2025.130821","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"130821"}}