{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T02:24:53Z","timestamp":1779157493988,"version":"3.51.4"},"reference-count":49,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Basic Research Program of China","doi-asserted-by":"crossref","award":["2013CB966802"],"award-info":[{"award-number":["2013CB966802"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31370762"],"award-info":[{"award-number":["31370762"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81372218"],"award-info":[{"award-number":["81372218"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"National Key Technology R&D Program of China","award":["2015BAI08B03"],"award-info":[{"award-number":["2015BAI08B03"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"published-print":{"date-parts":[[2017,8]]},"DOI":"10.1016\/j.bbagrm.2017.05.003","type":"journal-article","created":{"date-parts":[[2017,5,13]],"date-time":"2017-05-13T15:16:05Z","timestamp":1494688565000},"page":"885-893","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Coordinated regulation of IFITM1, 2 and 3 genes by an IFN-responsive enhancer through long-range chromatin interactions"],"prefix":"10.1016","volume":"1860","author":[{"given":"Ping","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Lei","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Long","family":"Shen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"De-Jian","family":"Xie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiang-Yuan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chao","family":"He","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Hu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbagrm.2017.05.003_bb0005","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/nri3787","article-title":"Type I interferons in infectious disease","volume":"15","author":"McNab","year":"2015","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0010","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1146\/annurev-immunol-032713-120231","article-title":"Interferon-stimulated genes: a complex web of host defenses","volume":"32","author":"Schneider","year":"2014","journal-title":"Annu. Rev. Immunol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0015","doi-asserted-by":"crossref","first-page":"e1002337","DOI":"10.1371\/journal.ppat.1002337","article-title":"IFITM3 inhibits influenza A virus infection by preventing cytosolic entry","volume":"7","author":"Feeley","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0020","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.1016\/j.cell.2009.12.017","article-title":"The IFITM proteins mediate cellular resistance to influenza A H1N1 virus, West Nile virus, and dengue virus","volume":"139","author":"Brass","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0025","doi-asserted-by":"crossref","first-page":"e1001258","DOI":"10.1371\/journal.ppat.1001258","article-title":"Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus","volume":"7","author":"Huang","year":"2011","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0030","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1038\/nri3344","article-title":"The broad-spectrum antiviral functions of IFIT and IFITM proteins","volume":"13","author":"Diamond","year":"2013","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0035","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1146\/annurev-virology-031413-085537","article-title":"IFITM-family proteins: the cell's first line of antiviral defense","volume":"1","author":"Bailey","year":"2014","journal-title":"Annu. Rev. Virol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0040","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nature10921","article-title":"IFITM3 restricts the morbidity and mortality associated with influenza","volume":"484","author":"Everitt","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0045","doi-asserted-by":"crossref","first-page":"1418","DOI":"10.1038\/ncomms2433","article-title":"Interferon-induced transmembrane protein-3 genetic variant rs12252-C is associated with severe influenza in Chinese individuals","volume":"4","author":"Zhang","year":"2013","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0050","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1073\/pnas.1321748111","article-title":"Early hypercytokinemia is associated with interferon-induced transmembrane protein-3 dysfunction and predictive of fatal H7N9 infection","volume":"111","author":"Wang","year":"2014","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0055","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1093\/infdis\/jit468","article-title":"IFITM3 and susceptibility to respiratory viral infections in the community","volume":"209","author":"Mills","year":"2014","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0060","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1016\/j.devcel.2005.10.010","article-title":"IFITM\/Mil\/fragilis family proteins IFITM1 and IFITM3 play distinct roles in mouse primordial germ cell homing and repulsion","volume":"9","author":"Tanaka","year":"2005","journal-title":"Dev. Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0065","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1089\/jir.2006.26.462","article-title":"Differential gene induction by type I and type II interferons and their combination","volume":"26","author":"Sanda","year":"2006","journal-title":"J. Interf. Cytokine Res."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0070","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1038\/nri1604","article-title":"Mechanisms of type-I- and type-II-interferon-mediated signalling","volume":"5","author":"Platanias","year":"2005","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0075","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/ncb855","article-title":"Chromatin-remodelling factor BRG1 selectively activates a subset of interferon-alpha-inducible genes","volume":"4","author":"Huang","year":"2002","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0080","doi-asserted-by":"crossref","first-page":"6471","DOI":"10.1128\/MCB.22.18.6471-6479.2002","article-title":"Maximal induction of a subset of interferon target genes requires the chromatin-remodeling activity of the BAF complex","volume":"22","author":"Liu","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0085","doi-asserted-by":"crossref","first-page":"4476","DOI":"10.1128\/MCB.24.10.4476-4486.2004","article-title":"The chromatin-remodeling BAF complex mediates cellular antiviral activities by promoter priming","volume":"24","author":"Cui","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0090","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1016\/j.febslet.2007.12.033","article-title":"Transcriptional enhancer factor 1 (TEF-1\/TEAD1) mediates activation of IFITM3 gene by BRGl","volume":"582","author":"Cuddapah","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0095","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1038\/nature12753","article-title":"Topology of mammalian developmental enhancers and their regulatory landscapes","volume":"502","author":"Laat","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0100","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/S1074-7613(03)00179-1","article-title":"Regulation of the Th2 cytokine locus by a locus control region","volume":"19","author":"Lee","year":"2003","journal-title":"Immunity"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0105","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1016\/0092-8674(95)90136-1","article-title":"Virus induction of human IFN-\u03b2 gene assembly of an enhanceosome","volume":"83","author":"Thanos","year":"1995","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0110","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.tig.2015.11.004","article-title":"Enhanced identification of transcriptional enhancers provides mechanistic insights into diseases","volume":"32","author":"Murakawa","year":"2016","journal-title":"Trends Genet."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0115","doi-asserted-by":"crossref","DOI":"10.1093\/oxfordjournals.aje.a118408","article-title":"A simple method of estimating fifty percent endpoints","volume":"27","author":"Reed","year":"1938","journal-title":"Am. J. Epidemiol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0120","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.bbamcr.2014.12.002","article-title":"Involvement of aberrant miR-139\/Jun feedback loop in human gastric cancer","volume":"1853","author":"Zhang","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0125","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1126\/science.1067799","article-title":"Capturing chromosome conformation","volume":"295","author":"Dekker","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0130","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/nature08451","article-title":"Genomic views of distant-acting enhancers","volume":"461","author":"Visel","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0135","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.cell.2011.12.014","article-title":"Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation","volume":"148","author":"Li","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0140","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1146\/annurev-genom-090711-163723","article-title":"Characterization of enhancer function from genome-wide analyses","volume":"13","author":"Maston","year":"2012","journal-title":"Genomics Hum. Genet."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0145","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/j.molcel.2014.06.015","article-title":"Enhancer function: mechanistic and genome-wide insights come together","volume":"55","author":"Plank","year":"2014","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0150","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1038\/nature11245","article-title":"Architecture of the human regulatory network derived from ENCODE data","volume":"489","author":"Gerstein","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0155","doi-asserted-by":"crossref","first-page":"417","DOI":"10.1111\/j.1432-1033.1991.tb16139.x","article-title":"Molecular analysis of a human interferon-inducible gene family","volume":"199","author":"Lewin","year":"1991","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0160","doi-asserted-by":"crossref","first-page":"5096","DOI":"10.1128\/MCB.02454-05","article-title":"Active chromatin hub of the mouse alpha-globin locus forms in a transcription factory of clustered housekeeping genes","volume":"26","author":"Zhou","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0165","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/S1097-2765(02)00781-5","article-title":"Looping and interaction between hypersensitive sites in the active \u03b2-globin locus","volume":"10","author":"Tolhuis","year":"2002","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0170","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/nature11279","article-title":"The long-range interaction landscape of gene promoters","volume":"489","author":"Sanyal","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0175","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/nature12644","article-title":"A high-resolution map of the three-dimensional chromatin interactome in human cells","volume":"503","author":"Jin","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0180","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.cell.2011.10.023","article-title":"A regulatory archipelago controls Hox genes transcription in digits","volume":"147","author":"Montavon","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0185","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1101\/gad.1371305","article-title":"Global changes in STAT target selection and transcription regulation upon interferon treatments","volume":"19","author":"Stephen","year":"2005","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0190","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1101\/gr.5574907","article-title":"Mapping the chromosomal targets of STAT1 by Sequence Tag Analysis of Genomic Enrichment (STAGE)","volume":"17","author":"Bhinge","year":"2007","journal-title":"Genome Res."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0195","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1038\/nmeth1068","article-title":"Genome-wide profiles of STAT1 DNA association using chromatin immunoprecipitation and massively parallel sequencing","volume":"4","author":"Robertson","year":"2007","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0200","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.cell.2008.05.052","article-title":"Virus infection induces NF-\u03baB-dependent interchromosomal associations mediating monoallelic IFN-\u03b2 gene expression","volume":"134","author":"Apostolou","year":"2008","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0205","doi-asserted-by":"crossref","first-page":"12537","DOI":"10.1093\/nar\/gku1018","article-title":"A novel virus-inducible enhancer of the interferon-beta gene with tightly linked promoter and enhancer activities","volume":"42","author":"Banerjee","year":"2014","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0210","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/gtc.12316","article-title":"Distal regulatory element of the STAT1 gene potentially mediates positive feedback control of STAT1 expression","volume":"21","author":"Yuasa","year":"2016","journal-title":"Genes Cells"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0215","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1023\/A:1024922626726","article-title":"Spatial organization of gene expression: the active chromatin hub","volume":"11","author":"De","year":"2003","journal-title":"Chromosom. Res."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0220","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1038\/nature13417","article-title":"Enhancer loops appear stable during development and are associated with paused polymerase","volume":"512","author":"Ghavi-Helm","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0225","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.15252\/embr.201642198","article-title":"Capture-C reveals preformed chromatin interactions between HIF-binding sites and distant promoters","volume":"17","author":"Platt","year":"2016","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0230","doi-asserted-by":"crossref","first-page":"5810","DOI":"10.1093\/nar\/gkv506","article-title":"Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated by HIF-independent chromatin looping","volume":"43","author":"Schorg","year":"2015","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0235","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1016\/j.cell.2013.04.053","article-title":"Architectural protein subclasses shape 3D organization of genomes during lineage commitment","volume":"153","author":"Phillips-Cremins","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0240","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.cell.2014.09.033","article-title":"Enhancer interaction networks as a means for singular olfactory receptor expression","volume":"159","author":"Markenscoff-Papadimitriou","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.bbagrm.2017.05.003_bb0245","doi-asserted-by":"crossref","first-page":"e1005992","DOI":"10.1371\/journal.pgen.1005992","article-title":"Long-range chromosome interactions mediated by cohesin shape circadian gene expression","volume":"12","author":"Xu","year":"2016","journal-title":"PLoS Genet."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939917300299?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939917300299?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T22:08:34Z","timestamp":1589753314000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874939917300299"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8]]},"references-count":49,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2017,8]]}},"alternative-id":["S1874939917300299"],"URL":"https:\/\/doi.org\/10.1016\/j.bbagrm.2017.05.003","relation":{},"ISSN":["1874-9399"],"issn-type":[{"value":"1874-9399","type":"print"}],"subject":[],"published":{"date-parts":[[2017,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Coordinated regulation of IFITM1, 2 and 3 genes by an IFN-responsive enhancer through long-range chromatin interactions","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbagrm.2017.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}