{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T18:40:58Z","timestamp":1775673658715,"version":"3.50.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100009156","name":"Nantong Science and Technology Bureau","doi-asserted-by":"publisher","award":["JC2020101"],"award-info":[{"award-number":["JC2020101"]}],"id":[{"id":"10.13039\/501100009156","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100009576","name":"Nantong Municipal Commission of Health and Family Planning","doi-asserted-by":"publisher","award":["MA2020019"],"award-info":[{"award-number":["MA2020019"]}],"id":[{"id":"10.13039\/501100009576","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32000841"],"award-info":[{"award-number":["32000841"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32200940"],"award-info":[{"award-number":["32200940"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"published-print":{"date-parts":[[2022,11]]},"DOI":"10.1016\/j.bbagrm.2022.194875","type":"journal-article","created":{"date-parts":[[2022,10,5]],"date-time":"2022-10-05T12:26:27Z","timestamp":1664972787000},"page":"194875","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["Position-dependent effects of hnRNP A1\/A2 in SMN1\/2 exon7 splicing"],"prefix":"10.1016","volume":"1865","author":[{"given":"Jiaying","family":"Qiu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruobing","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengsi","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qingwen","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junjie","family":"Sun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbagrm.2022.194875_bb0005","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1146\/annurev-biochem-013118-111024","article-title":"How is precursor messenger rna spliced by the spliceosome?","volume":"89","author":"Wan","year":"2020","journal-title":"Annu. Rev. Biochem."},{"issue":"7","key":"10.1016\/j.bbagrm.2022.194875_bb0010","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrm.2017.27","article-title":"Alternative splicing as a regulator of development and tissue identity","volume":"18","author":"Baralle","year":"2017","journal-title":"Nat. Rev. Mol. Cell Biol."},{"issue":"12","key":"10.1016\/j.bbagrm.2022.194875_bb0015","doi-asserted-by":"crossref","first-page":"1413","DOI":"10.1038\/ng.259","article-title":"Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing","volume":"40","author":"Pan","year":"2008","journal-title":"Nat. Genet."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0020","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/wrna.100","article-title":"Evolution of Sr protein and Hnrnp splicing regulatory factors","volume":"3","author":"Busch","year":"2012","journal-title":"Wiley Interdiscip. Rev. RNA"},{"issue":"11","key":"10.1016\/j.bbagrm.2022.194875_bb0025","doi-asserted-by":"crossref","first-page":"6307","DOI":"10.1073\/pnas.96.11.6307","article-title":"A single nucleotide in the Smn gene regulates splicing and is responsible for spinal muscular atrophy","volume":"96","author":"Lorson","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbagrm.2022.194875_bb0030","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1146\/annurev-neuro-070918-050501","article-title":"Antisense oligonucleotide therapies for neurodegenerative diseases","volume":"42","author":"Bennett","year":"2019","journal-title":"Annu. Rev. Neurosci."},{"issue":"4","key":"10.1016\/j.bbagrm.2022.194875_bb0035","doi-asserted-by":"crossref","first-page":"834","DOI":"10.1016\/j.ajhg.2008.01.014","article-title":"Antisense masking of an hnrnp A1\/A2 intronic splicing silencer corrects Smn2 splicing in transgenic mice","volume":"82","author":"Hua","year":"2008","journal-title":"Am. J. Hum. Genet."},{"issue":"4","key":"10.1016\/j.bbagrm.2022.194875_bb0040","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.0050073","article-title":"Enhancement of Smn2 exon 7 inclusion by antisense oligonucleotides targeting the exon","volume":"5","author":"Hua","year":"2007","journal-title":"PLoS Biol."},{"issue":"8","key":"10.1016\/j.bbagrm.2022.194875_bb0045","article-title":"Hnrnp a\/B proteins: an encyclopedic assessment of their roles in homeostasis and disease","volume":"10","author":"Thibault","year":"2021","journal-title":"Biology (Basel)"},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0050","doi-asserted-by":"crossref","DOI":"10.1002\/wrna.1612","article-title":"The roles of Hnrnp A2\/B1 in Rna biology and disease","volume":"12","author":"Liu","year":"2021","journal-title":"Wiley Interdiscip. Rev. RNA"},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0055","doi-asserted-by":"crossref","first-page":"187","DOI":"10.3906\/biy-2010-29","article-title":"Compensatory expression regulation of highly homologous proteins Hnrnpa1 and Hnrnpa2","volume":"45","author":"Chang","year":"2021","journal-title":"Turk. J. Biol."},{"issue":"5","key":"10.1016\/j.bbagrm.2022.194875_bb0060","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1002\/j.1460-2075.1994.tb06369.x","article-title":"Rna binding specificity of hnrnp A1: significance of hnrnp A1 high-affinity binding sites in pre-mrna splicing","volume":"13","author":"Burd","year":"1994","journal-title":"EMBO J."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0065","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/nar\/gkab1280","article-title":"Systematic characterization of short intronic splicing-regulatory elements in Smn2 pre-mrna","volume":"50","author":"Gao","year":"2022","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagrm.2022.194875_bb0070","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s12915-016-0279-9","article-title":"Global identification of hnrnp A1 binding sites for sso-based splicing modulation","volume":"14","author":"Bruun","year":"2016","journal-title":"BMC Biol."},{"issue":"11","key":"10.1016\/j.bbagrm.2022.194875_bb0075","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1017\/S1355838202023075","article-title":"Hnrnp A1 controls Hiv-1 mrna splicing through cooperative binding to intron and exon splicing silencers in the context of a conserved secondary structure","volume":"8","author":"Damgaard","year":"2002","journal-title":"RNA"},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0080","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1086\/498853","article-title":"Determinants of exon 7 splicing in the spinal muscular atrophy genes, Smn1 and Smn2","volume":"78","author":"Cartegni","year":"2006","journal-title":"Am. J. Hum. Genet."},{"issue":"9","key":"10.1016\/j.bbagrm.2022.194875_bb0085","doi-asserted-by":"crossref","first-page":"3426","DOI":"10.1073\/pnas.0700343104","article-title":"An intronic element contributes to splicing repression in spinal muscular atrophy","volume":"104","author":"Kashima","year":"2007","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0090","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1002\/humu.21419","article-title":"Smn2 exon 7 splicing is inhibited by binding of hnrnp A1 to a common ess motif that spans the 3' splice site","volume":"32","author":"Doktor","year":"2011","journal-title":"Hum. Mutat."},{"issue":"14","key":"10.1016\/j.bbagrm.2022.194875_bb0095","doi-asserted-by":"crossref","first-page":"2768","DOI":"10.1093\/hmg\/ddx166","article-title":"A-44g transition in Smn2 intron 6 protects patients with spinal muscular atrophy","volume":"26","author":"Wu","year":"2017","journal-title":"Hum. Mol. Genet."},{"issue":"6","key":"10.1016\/j.bbagrm.2022.194875_bb0100","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1038\/s41573-021-00162-z","article-title":"Antisense technology: an overview and prospectus","volume":"20","author":"Crooke","year":"2021","journal-title":"Nat. Rev. Drug Discov."},{"issue":"12","key":"10.1016\/j.bbagrm.2022.194875_bb0105","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1080\/15476286.2019.1659080","article-title":"Modulation of Pdcd1 exon 3 splicing","volume":"16","author":"Sun","year":"2019","journal-title":"RNA Biol."},{"issue":"7457","key":"10.1016\/j.bbagrm.2022.194875_bb0110","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1038\/nature12311","article-title":"A compendium of rna-binding motifs for decoding gene regulation","volume":"499","author":"Ray","year":"2013","journal-title":"Nature"},{"issue":"13","key":"10.1016\/j.bbagrm.2022.194875_bb0115","doi-asserted-by":"crossref","first-page":"3568","DOI":"10.1093\/nar\/gkg616","article-title":"Esefinder: a web resource to identify exonic splicing enhancers","volume":"31","author":"Cartegni","year":"2003","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbagrm.2022.194875_bb0120","doi-asserted-by":"crossref","DOI":"10.3389\/fmolb.2021.659610","article-title":"A comprehensive analysis of the role of hnrnp A1 function and dysfunction in the pathogenesis of neurodegenerative disease","volume":"8","author":"Clarke","year":"2021","journal-title":"Front. Mol. Biosci."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0125","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1261\/rna.030486.111","article-title":"Mechanisms of activation and repression by the alternative splicing factors Rbfox1\/2","volume":"18","author":"Sun","year":"2012","journal-title":"RNA"},{"issue":"4","key":"10.1016\/j.bbagrm.2022.194875_bb0130","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1038\/ng854","article-title":"Disruption of an Sf2\/Asf-dependent exonic splicing enhancer in Smn2 causes spinal muscular atrophy in the absence of Smn1","volume":"30","author":"Cartegni","year":"2002","journal-title":"Nat. Genet."},{"issue":"4","key":"10.1016\/j.bbagrm.2022.194875_bb0135","doi-asserted-by":"crossref","first-page":"1333","DOI":"10.1128\/MCB.26.4.1333-1346.2006","article-title":"Splicing of a critical exon of human survival motor neuron is regulated by a unique silencer element located in the last intron","volume":"26","author":"Singh","year":"2006","journal-title":"Mol. Cell. Biol."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0140","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1006\/excr.1995.1366","article-title":"Cell type-specific expression of hnrnp proteins","volume":"221","author":"Kamma","year":"1995","journal-title":"Exp. Cell Res."},{"issue":"1\u20132","key":"10.1016\/j.bbagrm.2022.194875_bb0145","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1007\/s11010-016-2904-x","article-title":"Hnrnpa1 autoregulates its own mrna expression to remain non-cytotoxic","volume":"427","author":"Suzuki","year":"2017","journal-title":"Mol. Cell. Biochem."},{"issue":"6","key":"10.1016\/j.bbagrm.2022.194875_bb0150","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0350-21.2021","article-title":"Knock-down of heterogeneous nuclear ribonucleoprotein A1 results in neurite damage, altered stress granule biology, and cellular toxicity in differentiated neuronal cells","volume":"8","author":"Anees","year":"2021","journal-title":"eNeuro"},{"issue":"6","key":"10.1016\/j.bbagrm.2022.194875_bb0155","doi-asserted-by":"crossref","first-page":"4496","DOI":"10.1002\/jcp.30167","article-title":"Alternative splicing transitions associate with emerging atrophy phenotype during denervation-induced skeletal muscle atrophy","volume":"236","author":"Qiu","year":"2021","journal-title":"J. Cell. Physiol."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0160","doi-asserted-by":"crossref","DOI":"10.1098\/rsob.160303","article-title":"Muscle developmental defects in heterogeneous nuclear ribonucleoprotein A1 knockout mice","volume":"7","author":"Liu","year":"2017","journal-title":"Open Biol."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0165","doi-asserted-by":"crossref","first-page":"8640","DOI":"10.1038\/s41598-019-44714-1","article-title":"Functional roles of Hnrnpa2\/B1 regulated by Mettl3 in mammalian embryonic development","volume":"9","author":"Kwon","year":"2019","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0170","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.celrep.2012.02.001","article-title":"Integrative genome-wide analysis reveals cooperative regulation of alternative splicing by hnrnp proteins","volume":"1","author":"Huelga","year":"2012","journal-title":"Cell Rep."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0175","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1261\/rna.037044.112","article-title":"Position-dependent splicing activation and repression by sr and hnrnp proteins rely on common mechanisms","volume":"19","author":"Erkelenz","year":"2013","journal-title":"RNA"},{"issue":"10","key":"10.1016\/j.bbagrm.2022.194875_bb0180","doi-asserted-by":"crossref","first-page":"1389","DOI":"10.1261\/rna.075135.120","article-title":"Allosteric regulation of U1 snrnp by splicing regulatory proteins controls spliceosomal assembly","volume":"26","author":"Shenasa","year":"2020","journal-title":"RNA"},{"issue":"6","key":"10.1016\/j.bbagrm.2022.194875_bb0185","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1080\/15476286.2016.1176663","article-title":"Position-dependent activity of Celf2 in the regulation of splicing and implications for signal-responsive regulation in T cells","volume":"13","author":"Ajith","year":"2016","journal-title":"RNA Biol."},{"issue":"7","key":"10.1016\/j.bbagrm.2022.194875_bb0190","doi-asserted-by":"crossref","first-page":"4015","DOI":"10.1093\/nar\/gkt097","article-title":"Position-dependent and neuron-specific splicing regulation by the celf family rna-binding protein Unc-75 in caenorhabditis elegans","volume":"41","author":"Kuroyanagi","year":"2013","journal-title":"Nucleic Acids Res."},{"issue":"21","key":"10.1016\/j.bbagrm.2022.194875_bb0195","doi-asserted-by":"crossref","first-page":"12455","DOI":"10.1093\/nar\/gkx901","article-title":"A mechanism underlying position-specific regulation of alternative splicing","volume":"45","author":"Hamid","year":"2017","journal-title":"Nucleic Acids Res."},{"issue":"9","key":"10.1016\/j.bbagrm.2022.194875_bb0200","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.1038\/nsmb.1881","article-title":"Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by ptb","volume":"17","author":"Llorian","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"issue":"4","key":"10.1016\/j.bbagrm.2022.194875_bb0205","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1038\/nn.2778","article-title":"Characterizing the rna targets and position-dependent splicing regulation by Tdp-43","volume":"14","author":"Tollervey","year":"2011","journal-title":"Nat. Neurosci."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0210","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1172\/JCI120279","article-title":"Splicing factor Srsf1 promotes gliomagenesis via oncogenic splice-switching of Myo1b","volume":"129","author":"Zhou","year":"2019","journal-title":"J. Clin. Invest."},{"issue":"20","key":"10.1016\/j.bbagrm.2022.194875_bb0215","doi-asserted-by":"crossref","first-page":"5620","DOI":"10.1128\/MCB.01678-08","article-title":"Cooperative-binding and splicing-repressive properties of hnrnp A1","volume":"29","author":"Okunola","year":"2009","journal-title":"Mol. Cell. Biol."},{"issue":"9","key":"10.1016\/j.bbagrm.2022.194875_bb0220","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1101\/gad.13.9.1102","article-title":"Crystal structure of the two-rrm domain of hnrnp A1 (Up1) complexed with single-stranded telomeric DNA","volume":"13","author":"Ding","year":"1999","journal-title":"Genes Dev."},{"issue":"5","key":"10.1016\/j.bbagrm.2022.194875_bb0225","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1016\/j.molcel.2012.12.025","article-title":"Hnrnp L and hnrnp A1 induce extended U1 snrna interactions with an exon to repress spliceosome assembly","volume":"49","author":"Chiou","year":"2013","journal-title":"Mol. Cell"},{"issue":"3","key":"10.1016\/j.bbagrm.2022.194875_bb0230","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1016\/j.molcel.2011.11.033","article-title":"Hnrnp A1 proofreads 3' splice site recognition by U2af","volume":"45","author":"Tavanez","year":"2012","journal-title":"Mol. Cell"},{"issue":"5","key":"10.1016\/j.bbagrm.2022.194875_bb0235","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1101\/gr.229062.117","article-title":"Hnrnpa1 promotes recognition of splice site decoys by U2af2 in vivo","volume":"28","author":"Howard","year":"2018","journal-title":"Genome Res."},{"issue":"7","key":"10.1016\/j.bbagrm.2022.194875_bb0240","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1016\/j.cell.2008.10.046","article-title":"Dynamic regulation of alternative splicing by silencers that modulate 5' splice site competition","volume":"135","author":"Yu","year":"2008","journal-title":"Cell"},{"issue":"3","key":"10.1016\/j.bbagrm.2022.194875_bb0245","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1002\/humu.24149","article-title":"Identification of Srsf10 as a regulator of Smn2 iss-N1","volume":"42","author":"Frederiksen","year":"2021","journal-title":"Hum. Mutat."},{"issue":"2","key":"10.1016\/j.bbagrm.2022.194875_bb0250","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1101\/gad.209759.112","article-title":"Pick one, but be quick: 5' splice sites and the problems of too many choices","volume":"27","author":"Roca","year":"2013","journal-title":"Genes Dev."},{"issue":"3","key":"10.1016\/j.bbagrm.2022.194875_bb0255","doi-asserted-by":"crossref","first-page":"1211","DOI":"10.1074\/jbc.R700035200","article-title":"Combinatorial control of exon recognition","volume":"283","author":"Hertel","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"32","key":"10.1016\/j.bbagrm.2022.194875_bb0260","doi-asserted-by":"crossref","first-page":"9926","DOI":"10.1073\/pnas.1500639112","article-title":"Splicing inhibition of U2af65 leads to alternative exon skipping","volume":"112","author":"Cho","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"48","key":"10.1016\/j.bbagrm.2022.194875_bb0265","doi-asserted-by":"crossref","first-page":"45476","DOI":"10.1074\/jbc.M107632200","article-title":"Modulation of survival motor neuron pre-mrna splicing by inhibition of alternative 3' splice site pairing","volume":"276","author":"Lim","year":"2001","journal-title":"J. Biol. Chem."},{"issue":"43","key":"10.1016\/j.bbagrm.2022.194875_bb0270","doi-asserted-by":"crossref","first-page":"33641","DOI":"10.1074\/jbc.M005597200","article-title":"An intronic downstream enhancer promotes 3' splice site usage of a neural cell-specific exon","volume":"275","author":"Guo","year":"2000","journal-title":"J. Biol. Chem."},{"issue":"3","key":"10.1016\/j.bbagrm.2022.194875_bb0275","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1261\/rna.7261206","article-title":"Distal regulation of alternative splicing by splicing enhancer in equine Beta-casein intron 1","volume":"12","author":"Lenasi","year":"2006","journal-title":"RNA"},{"issue":"17","key":"10.1016\/j.bbagrm.2022.194875_bb0280","doi-asserted-by":"crossref","first-page":"8144","DOI":"10.1093\/nar\/gkt609","article-title":"An intronic structure enabled by a long-distance interaction serves as a novel target for splicing correction in spinal muscular atrophy","volume":"41","author":"Singh","year":"2013","journal-title":"Nucleic Acids Res."},{"issue":"11\u201312","key":"10.1016\/j.bbagrm.2022.194875_bb0285","article-title":"How rna structure dictates the usage of a critical exon of spinal muscular atrophy gene","volume":"1862","author":"Singh","year":"2019","journal-title":"Biochim. Biophys. Acta, Gene Regul. Mech."},{"issue":"20","key":"10.1016\/j.bbagrm.2022.194875_bb0290","doi-asserted-by":"crossref","first-page":"5464","DOI":"10.1093\/hmg\/ddu271","article-title":"Pmd patient mutations reveal a long-distance intronic interaction that regulates Plp1\/Dm20 alternative splicing","volume":"23","author":"Taube","year":"2014","journal-title":"Hum. Mol. Genet."},{"issue":"1","key":"10.1016\/j.bbagrm.2022.194875_bb0295","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1093\/nar\/gkaa1208","article-title":"Multiple competing rna structures dynamically control alternative splicing in the human Ate1 gene","volume":"49","author":"Kalinina","year":"2021","journal-title":"Nucleic Acids Res."},{"issue":"12","key":"10.1016\/j.bbagrm.2022.194875_bb0300","doi-asserted-by":"crossref","first-page":"1434","DOI":"10.1038\/nsmb.2699","article-title":"Rbfox proteins regulate alternative mrna splicing through evolutionarily conserved rna bridges","volume":"20","author":"Lovci","year":"2013","journal-title":"Nat. Struct. Mol. Biol."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939922000906?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939922000906?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T13:31:25Z","timestamp":1761744685000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874939922000906"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":60,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,11]]}},"alternative-id":["S1874939922000906"],"URL":"https:\/\/doi.org\/10.1016\/j.bbagrm.2022.194875","relation":{},"ISSN":["1874-9399"],"issn-type":[{"value":"1874-9399","type":"print"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Position-dependent effects of hnRNP A1\/A2 in SMN1\/2 exon7 splicing","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbagrm.2022.194875","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"194875"}}