{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T15:26:17Z","timestamp":1771514777629,"version":"3.50.1"},"reference-count":46,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,9,1]],"date-time":"2024-09-01T00:00:00Z","timestamp":1725148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,6,16]],"date-time":"2024-06-16T00:00:00Z","timestamp":1718496000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007065","name":"University of Salerno","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"published-print":{"date-parts":[[2024,9]]},"DOI":"10.1016\/j.bbagrm.2024.195048","type":"journal-article","created":{"date-parts":[[2024,6,15]],"date-time":"2024-06-15T16:01:48Z","timestamp":1718467308000},"page":"195048","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["H3K56 acetylation affects Candida albicans morphology and secreted soluble factors interacting with the host"],"prefix":"10.1016","volume":"1867","author":[{"given":"Marisa","family":"Conte","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Eletto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martina","family":"Pannetta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Esposito","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Chiara","family":"Monti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elva","family":"Morretta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Tessarz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Silvana","family":"Morello","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra","family":"Tosco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amalia","family":"Porta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0005","doi-asserted-by":"crossref","first-page":"119","DOI":"10.4161\/viru.22913","article-title":"Candida albicans pathogenicity mechanisms","volume":"4","author":"Mayer","year":"2013","journal-title":"Virulence"},{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0010","doi-asserted-by":"crossref","first-page":"79","DOI":"10.3390\/jof7020079","article-title":"Candida albicans-the virulence factors and clinical manifestations of infection","volume":"7","author":"Talapko","year":"2021","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.bbagrm.2024.195048_bb0015","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.833655","article-title":"Genetic screening of Candida albicans inactivation mutants identifies new genes involved in macrophage-fungal cell interactions","volume":"13","author":"Godoy","year":"2022","journal-title":"Front. Microbiol."},{"issue":"6","key":"10.1016\/j.bbagrm.2024.195048_bb0020","doi-asserted-by":"crossref","first-page":"1642","DOI":"10.1172\/JCI27114","article-title":"Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors","volume":"116","author":"Netea","year":"2006","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbagrm.2024.195048_bb0025","first-page":"102","article-title":"Role of cell wall polysaccharides during recognition of Candida albicans by the innate immune system","volume":"1","author":"Perez-Garcia","year":"2011","journal-title":"J Glycobiology"},{"issue":"6","key":"10.1016\/j.bbagrm.2024.195048_bb0030","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.01874-14","article-title":"Candida albicans hypha formation and mannan masking of \u03b2-glucan inhibit macrophage phagosome maturation","volume":"5","author":"Bain","year":"2014","journal-title":"mBio"},{"issue":"1","key":"10.1016\/j.bbagrm.2024.195048_bb0035","doi-asserted-by":"crossref","first-page":"4260","DOI":"10.1038\/s41467-018-06607-1","article-title":"The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes","volume":"9","author":"Kasper","year":"2018","journal-title":"Nat Commun."},{"issue":"6","key":"10.1016\/j.bbagrm.2024.195048_bb0040","doi-asserted-by":"crossref","first-page":"2132","DOI":"10.1096\/fj.12-214353","article-title":"Candida albicans secreted aspartic proteases 4-6 induce apoptosis of epithelial cells by a novel Trojan horse mechanism","volume":"27","author":"Wu","year":"2013","journal-title":"FASEB J."},{"issue":"7","key":"10.1016\/j.bbagrm.2024.195048_bb0045","doi-asserted-by":"crossref","first-page":"2982","DOI":"10.1128\/AEM.67.7.2982-2992.2001","article-title":"Quorum sensing in the dimorphic fungus Candida albicans is mediated by farnesol","volume":"67","author":"Hornby","year":"2001","journal-title":"Appl. Environ. Microbiol."},{"issue":"9","key":"10.1016\/j.bbagrm.2024.195048_bb0050","doi-asserted-by":"crossref","first-page":"294","DOI":"10.15698\/mic2017.09.589","article-title":"Farnesol inhibits translation to limit growth and filamentation in C. albicans and S. cerevisiae","volume":"4","author":"Egbe","year":"2017","journal-title":"Microb Cell."},{"issue":"11","key":"10.1016\/j.bbagrm.2024.195048_bb0055","doi-asserted-by":"crossref","first-page":"5459","DOI":"10.1128\/AEM.68.11.5459-5463.2002","article-title":"Inhibition of Candida albicans biofilm formation by farnesol, a quorum-sensing molecule","volume":"68","author":"Ramage","year":"2002","journal-title":"Appl. Environ. Microbiol."},{"issue":"5","key":"10.1016\/j.bbagrm.2024.195048_bb0060","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02347-19","article-title":"Remasking of Candida albicans \u03b2-glucan in response to environmental pH is regulated by quorum sensing","volume":"10","author":"Cottier","year":"2019","journal-title":"mBio"},{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0065","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00143-15","article-title":"The fungal quorum-sensing molecule farnesol activates innate immune cells but suppresses cellular adaptive immunity","volume":"6","author":"Leonhardt","year":"2015","journal-title":"mBio"},{"issue":"10","key":"10.1016\/j.bbagrm.2024.195048_bb0070","doi-asserted-by":"crossref","first-page":"3857","DOI":"10.1128\/IAI.00886-15","article-title":"Candida albicans quorum sensing molecules stimulate mouse macrophage migration","volume":"83","author":"Hargarten","year":"2015","journal-title":"Infect. Immun."},{"issue":"12","key":"10.1016\/j.bbagrm.2024.195048_bb0075","doi-asserted-by":"crossref","first-page":"1611","DOI":"10.3390\/cells8121611","article-title":"Farnesol, a quorum-sensing molecule of Candida albicans triggers the release of neutrophil extracellular traps","volume":"8","author":"Zawrotniak","year":"2019","journal-title":"Cells"},{"issue":"6","key":"10.1016\/j.bbagrm.2024.195048_bb0080","doi-asserted-by":"crossref","DOI":"10.1128\/mbio.02605-22","article-title":"Nature of \u03b2-1,3-glucan-exposing features on Candida albicans cell wall and their modulation","volume":"13","author":"de Assis","year":"2022","journal-title":"mBio"},{"issue":"13","key":"10.1016\/j.bbagrm.2024.195048_bb0085","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.cub.2006.06.023","article-title":"The sirtuins hst3 and Hst4p preserve genome integrity by controlling histone h3 lysine 56 deacetylation","volume":"16","author":"Celic","year":"2006","journal-title":"Curr. Biol."},{"issue":"7","key":"10.1016\/j.bbagrm.2024.195048_bb0090","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/nm.2175","article-title":"Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy","volume":"16","author":"Wurtele","year":"2010","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbagrm.2024.195048_bb0095","doi-asserted-by":"crossref","first-page":"1031814","DOI":"10.3389\/fcimb.2022.1031814","article-title":"Effects of Hst3p inhibition in Candida albicans: a genome-wide H3K56 acetylation analysis","volume":"12","author":"Conte","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"10","key":"10.1016\/j.bbagrm.2024.195048_bb0100","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202152435","article-title":"Nhp2 is a reader of H2AQ105me and part of a network integrating metabolism with rRNA synthesis","volume":"22","author":"Mawer","year":"2021","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbagrm.2024.195048_bb0105","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1186\/1756-0500-7-312","article-title":"A method for generating highly multiplexed ChIP-seq libraries","volume":"7","author":"Ford","year":"2014","journal-title":"BMC. Res. Notes"},{"key":"10.1016\/j.bbagrm.2024.195048_bb0110","author":"Iqbal","year":"2021","journal-title":"Flaski"},{"issue":"W1","key":"10.1016\/j.bbagrm.2024.195048_bb0115","doi-asserted-by":"crossref","first-page":"W537","DOI":"10.1093\/nar\/gky379","article-title":"The galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update","volume":"46","author":"Afgan","year":"2018","journal-title":"Nucleic Acids Res."},{"issue":"8","key":"10.1016\/j.bbagrm.2024.195048_bb0120","doi-asserted-by":"crossref","first-page":"2628","DOI":"10.1093\/bioinformatics\/btz931","article-title":"ShinyGO: a graphical gene-set enrichment tool for animals and plants","volume":"36","author":"Ge","year":"2020","journal-title":"Bioinformatics"},{"key":"10.1016\/j.bbagrm.2024.195048_bb0125","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2022.855229","article-title":"EFG1, everyone\u2019s favorite gene in Candida albicans: a comprehensive literature review","volume":"12","author":"Glazier","year":"2022","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"8","key":"10.1016\/j.bbagrm.2024.195048_bb0130","doi-asserted-by":"crossref","first-page":"1845","DOI":"10.1038\/sj.emboj.7600195","article-title":"Hgc1, a novel hypha-specific G1 cyclin-related protein regulates Candida albicans hyphal morphogenesis","volume":"23","author":"Zheng","year":"2004","journal-title":"EMBO J."},{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0135","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00206-20","article-title":"Ahr1 and Tup1 contribute to the transcriptional control of virulence-associated genes in Candida albicans","volume":"11","author":"Ruben","year":"2020","journal-title":"mBio"},{"key":"10.1016\/j.bbagrm.2024.195048_bb0140","doi-asserted-by":"crossref","first-page":"86","DOI":"10.3389\/fmicb.2019.00086","article-title":"Overproduction of phospholipids by the Kennedy pathway leads to Hypervirulence in Candida albicans","volume":"10","author":"Tams","year":"2019","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.bbagrm.2024.195048_bb0145","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/0378-1119(87)90027-8","article-title":"Peroxisomal acyl-coenzyme A oxidase multigene family of the yeast Candida tropicalis; nucleotide sequence of a third gene and its protein product","volume":"58","author":"Okazaki","year":"1987","journal-title":"Gene"},{"issue":"32","key":"10.1016\/j.bbagrm.2024.195048_bb0150","doi-asserted-by":"crossref","first-page":"24335","DOI":"10.1074\/jbc.M109.094250","article-title":"Contributions of carnitine acetyltransferases to intracellular acetyl unit transport in Candida albicans","volume":"285","author":"Strijbis","year":"2010","journal-title":"J. Biol. Chem."},{"issue":"4","key":"10.1016\/j.bbagrm.2024.195048_bb0155","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1128\/EC.00017-08","article-title":"Carnitine-dependent transport of acetyl coenzyme A in Candida albicans is essential for growth on nonfermentable carbon sources and contributes to biofilm formation","volume":"7","author":"Strijbis","year":"2008","journal-title":"Eukaryot. Cell"},{"issue":"10","key":"10.1016\/j.bbagrm.2024.195048_bb0160","doi-asserted-by":"crossref","first-page":"1733","DOI":"10.1128\/EC.00253-08","article-title":"Role of acetyl coenzyme A synthesis and breakdown in alternative carbon source utilization in Candida albicans","volume":"7","author":"Carman","year":"2008","journal-title":"Eukaryot. Cell"},{"issue":"11","key":"10.1016\/j.bbagrm.2024.195048_bb0165","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.3390\/cancers14112643","article-title":"A histone deacetylase inhibitor induces acetyl-CoA depletion leading to lethal metabolic stress in RAS-pathway activated cells","volume":"14","author":"Basseville","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"3","key":"10.1016\/j.bbagrm.2024.195048_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0033362","article-title":"Evaluation of the role of Candida albicans agglutinin-like sequence (Als) proteins in human oral epithelial cell interactions","volume":"7","author":"Murciano","year":"2012","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0175","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/mmi.14727","article-title":"The zinc cluster transcription factor Czf1 regulates cell wall architecture and integrity in Candida albicans","volume":"116","author":"Mottola","year":"2021","journal-title":"Mol. Microbiol."},{"issue":"9","key":"10.1016\/j.bbagrm.2024.195048_bb0180","doi-asserted-by":"crossref","first-page":"1281","DOI":"10.1128\/EC.00311-12","article-title":"Candida albicans Czf1 and Efg1 coordinate the response to farnesol during quorum sensing, white-opaque thermal dimorphism, and cell death","volume":"12","author":"Langford","year":"2013","journal-title":"Eukaryot. Cell"},{"issue":"3","key":"10.1016\/j.bbagrm.2024.195048_bb0185","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0058613","article-title":"A core filamentation response network in Candida albicans is restricted to eight genes","volume":"8","author":"Martin","year":"2013","journal-title":"PloS One"},{"issue":"34","key":"10.1016\/j.bbagrm.2024.195048_bb0190","doi-asserted-by":"crossref","first-page":"12813","DOI":"10.1073\/pnas.0605270103","article-title":"Bistable expression of WOR1, a master regulator of white-opaque switching in Candida albicans","volume":"103","author":"Huang","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.bbagrm.2024.195048_bb0195","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0191194","article-title":"Accessibility and contribution to glucan masking of natural and genetically tagged versions of yeast wall protein 1 of Candida albicans","volume":"13","author":"Granger","year":"2018","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.bbagrm.2024.195048_bb0200","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1574-6968.2000.tb09235.x","article-title":"Cellular actin is affected by interaction with Candida albicans","volume":"189","author":"Tsarfaty","year":"2000","journal-title":"FEMS Microbiol. Lett."},{"issue":"3","key":"10.1016\/j.bbagrm.2024.195048_bb0205","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/13693780701837157","article-title":"Candida albicans metabolite affects the cytoskeleton and phagocytic activity of murine macrophages","volume":"46","author":"Schindler","year":"2008","journal-title":"Med. Mycol."},{"issue":"8","key":"10.1016\/j.bbagrm.2024.195048_bb0210","doi-asserted-by":"crossref","first-page":"4938","DOI":"10.1128\/AEM.71.8.4938-4940.2005","article-title":"Farnesol concentrations required to block germ tube formation in Candida albicans in the presence and absence of serum","volume":"71","author":"Mosel","year":"2005","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bbagrm.2024.195048_bb0215","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.2217\/fmb-2019-0343","article-title":"Histone acetylation\/deacetylation in Candida albicans and their potential as antifungal targets","volume":"15","author":"Su","year":"2020","journal-title":"Future Microbiol."},{"issue":"7","key":"10.1016\/j.bbagrm.2024.195048_bb0220","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0966-842X(01)02094-7","article-title":"Virulence factors of Candida albicans","volume":"9","author":"Calderone","year":"2001","journal-title":"Trends Microbiol."},{"issue":"5","key":"10.1016\/j.bbagrm.2024.195048_bb0225","doi-asserted-by":"crossref","first-page":"392","DOI":"10.3390\/jof7050392","article-title":"Candida albicans\/macrophage biointerface on human and porcine decellularized adipose matrices","volume":"7","author":"Cicu\u00e9ndez","year":"2021","journal-title":"J Fungi (Basel)."},{"key":"10.1016\/j.bbagrm.2024.195048_bb0230","doi-asserted-by":"crossref","first-page":"4006","DOI":"10.1128\/IAI.00397-07","article-title":"Exogenous farnesol interferes with the normal progression of cytokine expression during candidiasis in a mouse model","volume":"75","author":"Navarathna","year":"2007","journal-title":"Infect. Immun."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939924000440?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1874939924000440?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,10,6]],"date-time":"2024-10-06T12:38:28Z","timestamp":1728218308000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1874939924000440"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":46,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2024,9]]}},"alternative-id":["S1874939924000440"],"URL":"https:\/\/doi.org\/10.1016\/j.bbagrm.2024.195048","relation":{},"ISSN":["1874-9399"],"issn-type":[{"value":"1874-9399","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"H3K56 acetylation affects Candida albicans morphology and secreted soluble factors interacting with the host","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbagrm.2024.195048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"195048"}}