{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T10:07:38Z","timestamp":1760954858099},"reference-count":21,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2006,9,1]],"date-time":"2006-09-01T00:00:00Z","timestamp":1157068800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2006,9]]},"DOI":"10.1016\/j.bbalip.2006.07.006","type":"journal-article","created":{"date-parts":[[2006,7,22]],"date-time":"2006-07-22T11:17:05Z","timestamp":1153567025000},"page":"1100-1106","source":"Crossref","is-referenced-by-count":6,"title":["Role of leucine zipper motif in apoE3 N-terminal domain lipid binding activity"],"prefix":"10.1016","volume":"1761","author":[{"given":"Taichi","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert O.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbalip.2006.07.006_bib1","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0065-3233(08)60642-7","article-title":"Apolipoprotein E: structure\u2013function relationships","volume":"45","author":"Weisgraber","year":"1994","journal-title":"Adv. Protein Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib2","doi-asserted-by":"crossref","first-page":"6249","DOI":"10.1016\/S0021-9258(18)68779-4","article-title":"Human apolipoprotein E3 in aqueous solution. II. Properties of the amino- and carboxyl-terminal domains","volume":"263","author":"Aggerbeck","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib3","doi-asserted-by":"crossref","first-page":"6240","DOI":"10.1016\/S0021-9258(18)68778-2","article-title":"Human apolipoprotein E3 in aqueous solution. I. Evidence for two structural domains","volume":"263","author":"Wetterau","year":"1988","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib4","doi-asserted-by":"crossref","first-page":"12341","DOI":"10.1016\/S0021-9258(17)44180-9","article-title":"The receptor-binding domain of human apolipoprotein E. Binding of apolipoprotein E fragments","volume":"258","author":"Innerarity","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib5","doi-asserted-by":"crossref","first-page":"16375","DOI":"10.1016\/S0021-9258(17)36247-6","article-title":"Behavior of human apolipoprotein E in aqueous solutions and at interfaces","volume":"260","author":"Yokoyama","year":"1985","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib6","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1126\/science.2063194","article-title":"Three-dimensional structure of the LDL receptor-binding domain of human apolipoprotein E","volume":"252","author":"Wilson","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.bbalip.2006.07.006_bib7","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1016\/S0022-2275(20)42621-5","article-title":"Apolipoprotein E distribution among human plasma lipoproteins: role of the cysteine-arginine interchange at residue 112","volume":"31","author":"Weisgraber","year":"1990","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2006.07.006_bib8","doi-asserted-by":"crossref","first-page":"15745","DOI":"10.1016\/S0021-9258(18)82318-3","article-title":"Discrete carboxyl-terminal segments of apolipoprotein E mediate lipoprotein association and protein oligomerization","volume":"268","author":"Westerlund","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib9","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/S1388-1981(99)00176-6","article-title":"The molecular basis of exchangeable apolipoprotein function","volume":"1483","author":"Narayanaswami","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2006.07.006_bib10","doi-asserted-by":"crossref","first-page":"37853","DOI":"10.1074\/jbc.M102953200","article-title":"Lipid association-induced N- and C-terminal domain reorganization in human apolipoprotein E3","volume":"276","author":"Narayanaswami","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib11","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1139\/o97-007","article-title":"Bacterial overexpression, isotope enrichment and NMR analysis of the N-terminal domain of human apolipoprotein E","volume":"75","author":"Fisher","year":"1997","journal-title":"Biochem. Cell. Biol."},{"key":"10.1016\/j.bbalip.2006.07.006_bib12","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1016\/S0022-2836(65)80111-5","article-title":"The interaction of a naphthalene dye with apomyoglobin. A fluorescent probe for non polar binding sites","volume":"13","author":"Stryer","year":"1965","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbalip.2006.07.006_bib13","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1194\/jlr.D600001-JLR200","article-title":"Characterization of low-density lipoprotein receptor ligand interactions by fluorescence resonance energy transfer","volume":"47","author":"Yamamoto","year":"2006","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2006.07.006_bib14","doi-asserted-by":"crossref","first-page":"3728","DOI":"10.1046\/j.1432-1327.2001.02282.x","article-title":"Modulation of the lipid binding properties of the N-terminal domain of human apolipoprotein E3","volume":"268","author":"Weers","year":"2001","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib15","doi-asserted-by":"crossref","first-page":"21804","DOI":"10.1074\/jbc.274.31.21804","article-title":"Interaction of an exchangeable apolipoprotein with phospholipid vesicles and lipoprotein particles. Role of leucines 32, 34 and 95 in Locusta migratoria apolipophorin III","volume":"274","author":"Weers","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib16","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/j.1742-4658.2005.05089.x","article-title":"Replacement of helix 1\u2032 enhances the lipid binding activity of apoE3 N-terminal domain","volume":"273","author":"Redmond","year":"2006","journal-title":"FEBS J."},{"key":"10.1016\/j.bbalip.2006.07.006_bib17","doi-asserted-by":"crossref","first-page":"25825","DOI":"10.1074\/jbc.273.40.25825","article-title":"The LDL receptor active conformation of apolipoprotein E. Helix organization in N-terminal domain-phospholipid disc particles","volume":"273","author":"Raussens","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib18","doi-asserted-by":"crossref","first-page":"33601","DOI":"10.1074\/jbc.M002643200","article-title":"The lipid associated conformation of the receptor binding domain of human apolipoprotein E","volume":"275","author":"Fisher","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib19","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0014-5793(93)81730-N","article-title":"Prevention of phospholipase-C induced aggregation of low density lipoprotein by amphipathic apolipoproteins","volume":"316","author":"Liu","year":"1993","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbalip.2006.07.006_bib20","doi-asserted-by":"crossref","first-page":"40949","DOI":"10.1074\/jbc.M106337200","article-title":"Lipid binding-induced conformational change in human apolipoprotein E. Evidence for two lipid-bound states on spherical particles","volume":"276","author":"Saito","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2006.07.006_bib21","doi-asserted-by":"crossref","first-page":"14273","DOI":"10.1074\/jbc.M313318200","article-title":"Helix orientation of the functional domains in apolipoprotein E in discoidal high density lipoprotein particles","volume":"279","author":"Narayanaswami","year":"2004","journal-title":"J. Biol. Chem."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198106001983?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198106001983?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,30]],"date-time":"2021-07-30T05:00:11Z","timestamp":1627621211000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198106001983"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,9]]},"references-count":21,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2006,9]]}},"alternative-id":["S1388198106001983"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2006.07.006","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2006,9]]}}}