{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T14:29:05Z","timestamp":1791296945197,"version":"4.1.0"},"reference-count":92,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2011,9,1]],"date-time":"2011-09-01T00:00:00Z","timestamp":1314835200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2011,9]]},"DOI":"10.1016\/j.bbalip.2011.06.006","type":"journal-article","created":{"date-parts":[[2011,6,24]],"date-time":"2011-06-24T01:43:27Z","timestamp":1308879807000},"page":"498-507","source":"Crossref","is-referenced-by-count":140,"title":["Phytanic acid metabolism in health and disease"],"prefix":"10.1016","volume":"1811","author":[{"given":"Ronald J.A.","family":"Wanders","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasper","family":"Komen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sacha","family":"Ferdinandusse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbalip.2011.06.006_bb0005","first-page":"150","article-title":"Der Abbau aromatischer Fettsa\u00fcren im Tierk\u00f6rper","volume":"6","author":"Knoop","year":"1904","journal-title":"Beitr. Chem. Physiol. Pathol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0010","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/S0021-9258(18)43110-9","article-title":"Acetylation of sulfanilamide by liver homogenates and extracts","volume":"160","author":"Lipmann","year":"1945","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0015","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0021-9258(17)41419-0","article-title":"A common factor in the enzymatic acetylation of sulfanilamide and of choline","volume":"162","author":"Lipmann","year":"1946","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0020","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1042\/bj0280031","article-title":"Researches on fat metabolism II","volume":"28","author":"Verkade","year":"1934","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0025","first-page":"1","article-title":"Heredopathia atactica polyneuritiformis","volume":"Suppl. 38","author":"Refsum","year":"1946","journal-title":"Acta Psychiatr. Scand."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0030","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1515\/bchm2.1963.333.1.133","article-title":"Ueber das Vorkommen der 3,7,11,15-Tetramethylhexadecansaure (Phytans\u00e4ure) in den Cholesterinestern und anderen Lipidfraktionen der Organe bei einem Krankheitsfall unbekanter Genese (Verdacht auf Heredopathia atactica polyneuritiformis, Refsum's syndrome)","volume":"333","author":"Klenk","year":"1963","journal-title":"Hoppe Seylers Z. Physiol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0035","first-page":"73","article-title":"Untersuchungen uber Phytol","volume":"378","author":"Willstaetter","year":"1911","journal-title":"Liebigs Ann."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0040","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1042\/bj0500358","article-title":"The branched chain fatty acids of butterfat. II. Isolation of a multibranched, C20 saturated fatty acid fraction.","volume":"50","author":"Hansen","year":"1952","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0045","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1016\/0006-291X(66)90786-8","article-title":"A pathway for oxidative degradation of phytanic acid in mammals","volume":"25","author":"Mize","year":"1966","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0050","first-page":"178","article-title":"Heredopathia atactica polyneuritiformis (Refum's disease)\u2014a defect in the omega-oxidation mechanism of fatty acids","volume":"17","author":"Eldjarn","year":"1965","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0055","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/0006-291X(65)90328-1","article-title":"Conversion of U-C14-phytol to phytanic acid and its oxidation in heredopathia atactica polyneuritiformis","volume":"19","author":"Steinberg","year":"1965","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0060","doi-asserted-by":"crossref","first-page":"26838","DOI":"10.1074\/jbc.M501861200","article-title":"Characterization of the final step in the conversion of phytol into phytanic acid","volume":"280","author":"van den Brink","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0065","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.ymgme.2004.01.019","article-title":"Identification of fatty aldehyde dehydrogenase in the breakdown of phytol to phytanic acid","volume":"82","author":"van den Brink","year":"2004","journal-title":"Mol. Genet. Metab."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0070","doi-asserted-by":"crossref","first-page":"1752","DOI":"10.1007\/s00018-005-5463-y","article-title":"Phytanic acid: production from phytol, its breakdown and role in human disease","volume":"63","author":"van den Brink","year":"2006","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0075","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1086\/302681","article-title":"The molecular basis of Sjogren\u2013Larsson syndrome: mutation analysis of the fatty aldehyde dehydrogenase gene","volume":"65","author":"Rizzo","year":"1999","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0080","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/0005-2760(85)90027-X","article-title":"In vitro conversion of phytol to phytanic acid in rat liver: subcellular distribution of activity and chemical characterization of intermediates using a new bromination technique","volume":"835","author":"Muralidharan","year":"1985","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0085","doi-asserted-by":"crossref","first-page":"2092","DOI":"10.1016\/j.febslet.2006.03.011","article-title":"Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation","volume":"580","author":"Gloerich","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0090","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/S1388-1981(03)00003-9","article-title":"Phytanic acid alpha-oxidation, new insights into an old problem: a review","volume":"1631","author":"Wanders","year":"2003","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0095","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/BF02537036","article-title":"Very long chain fatty acids in higher animals\u2014a review","volume":"30","author":"Poulos","year":"1995","journal-title":"Lipids"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0100","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/0003-9861(92)90565-E","article-title":"Alpha-oxidation of 3-methyl-substituted fatty acids in rat liver","volume":"296","author":"Huang","year":"1992","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0105","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/0005-2760(93)90239-6","article-title":"Studies on phytanic acid alpha-oxidation in rat liver and cultured human skin fibroblasts","volume":"1167","author":"Wanders","year":"1993","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0110","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1042\/bj2920457","article-title":"Formic acid is a product of the alpha-oxidation of fatty acids by human skin fibroblasts: deficiency of formic acid production in peroxisome-deficient fibroblasts","volume":"292","author":"Poulos","year":"1993","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0115","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1016\/0005-2760(94)90075-2","article-title":"Phytanic acid must be activated to phytanoyl-CoA prior to its alpha-oxidation in rat liver peroxisomes","volume":"1214","author":"Watkins","year":"1994","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0120","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1111\/j.1432-1033.1996.0674h.x","article-title":"Alpha-oxidation of 3-methyl-substituted fatty acids in rat liver. Production of formic acid instead of CO2, cofactor requirements, subcellular localization and formation of a 2-hydroxy-3-methylacyl-CoA intermediate","volume":"240","author":"Croes","year":"1996","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0125","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1006\/bbrc.1996.1781","article-title":"Phytanoyl-CoA hydroxylase is present in human liver, located in peroxisomes, and deficient in Zellweger syndrome: direct, unequivocal evidence for the new, revised pathway of phytanic acid alpha-oxidation in humans","volume":"229","author":"Jansen","year":"1996","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0130","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1111\/j.1432-1033.1995.545zz.x","article-title":"Phytanic acid alpha-oxidation in rat liver peroxisomes. Production of alpha-hydroxyphytanoyl-CoA and formate is enhanced by dioxygenase cofactors","volume":"232","author":"Mihalik","year":"1995","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0135","doi-asserted-by":"crossref","first-page":"1958","DOI":"10.1194\/jlr.E400002-JLR200","article-title":"Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family","volume":"45","author":"Mashek","year":"2004","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0140","doi-asserted-by":"crossref","first-page":"1773","DOI":"10.1074\/jbc.R700037200","article-title":"Very long-chain acyl-CoA synthetases","volume":"283","author":"Watkins","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0145","doi-asserted-by":"crossref","first-page":"24674","DOI":"10.1074\/jbc.M102036200","article-title":"Acyl-CoA synthetase isoforms 1, 4, and 5 are present in different subcellular membranes in rat liver and can be inhibited independently","volume":"276","author":"Lewin","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0150","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1006\/bbrc.1999.0510","article-title":"Human very-long-chain acyl-CoA synthetase: cloning, topography, and relevance to branched-chain fatty acid metabolism","volume":"257","author":"Steinberg","year":"1999","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0155","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1093\/hmg\/ddg126","article-title":"A very long-chain acyl-CoA synthetase-deficient mouse and its relevance to X-linked adrenoleukodystrophy","volume":"12","author":"Heinzer","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0160","doi-asserted-by":"crossref","first-page":"2244","DOI":"10.1016\/S0022-2275(20)32099-X","article-title":"Phytanoyl-CoA hydroxylase from rat liver. Protein purification and cDNA cloning with implications for the subcellular localization of phytanic acid alpha-oxidation","volume":"40","author":"Jansen","year":"1999","journal-title":"J. Lipid. Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0165","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1038\/sj.emboj.7601525","article-title":"Novel peroxisomal protease Tysnd1 processes PTS1- and PTS2-containing enzymes involved in beta-oxidation of fatty acids","volume":"26","author":"Kurochkin","year":"2007","journal-title":"EMBO J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0170","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S1074-5521(02)00139-4","article-title":"Utilization of sterol carrier protein-2 by phytanoyl-CoA 2-hydroxylase in the peroxisomal alpha oxidation of phytanic acid","volume":"9","author":"Mukherji","year":"2002","journal-title":"Chem. Biol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0175","doi-asserted-by":"crossref","first-page":"10039","DOI":"10.1073\/pnas.96.18.10039","article-title":"Purification, molecular cloning, and expression of 2-hydroxyphytanoyl-CoA lyase, a peroxisomal thiamine pyrophosphate-dependent enzyme that catalyzes the carbon\u2013carbon bond cleavage during alpha-oxidation of 3-methyl-branched fatty acids","volume":"96","author":"Foulon","year":"1999","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0180","doi-asserted-by":"crossref","first-page":"176","DOI":"10.1016\/S1388-1981(99)00126-2","article-title":"Phytanic acid alpha-oxidation: identification of 2-hydroxyphytanoyl-CoA lyase in rat liver and its localisation in peroxisomes","volume":"1440","author":"Jansen","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0185","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1006\/bbrc.2001.4835","article-title":"Identification of pristanal dehydrogenase activity in peroxisomes: conclusive evidence that the complete phytanic acid alpha-oxidation pathway is localized in peroxisomes","volume":"283","author":"Jansen","year":"2001","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0190","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0014-5793(98)00574-2","article-title":"Involvement of microsomal fatty aldehyde dehydrogenase in the alpha-oxidation of phytanic acid","volume":"429","author":"Verhoeven","year":"1998","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0195","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1042\/BST0350865","article-title":"Peroxisomes, Refsum's disease and the alpha- and omega-oxidation of phytanic acid","volume":"35","author":"Wanders","year":"2007","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0200","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1194\/jlr.R005959","article-title":"Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism","volume":"51","author":"Van Veldhoven","year":"2010","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0205","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/0005-2760(92)90056-2","article-title":"Characteristics and subcellular localization of pristanoyl-CoA synthetase in rat liver","volume":"1125","author":"Wanders","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0210","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1093\/oxfordjournals.jbchem.a021279","article-title":"Purification and properties of rat liver peroxisomal very-long-chain acyl-CoA synthetase","volume":"119","author":"Uchida","year":"1996","journal-title":"J. Biochem. (Tokyo)"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0215","doi-asserted-by":"crossref","first-page":"30360","DOI":"10.1074\/jbc.271.48.30360","article-title":"Molecular cloning of cDNA encoding rat very long-chain acyl-CoA synthetase","volume":"271","author":"Uchiyama","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0220","doi-asserted-by":"crossref","first-page":"24771","DOI":"10.1074\/jbc.M203295200","article-title":"Participation of two members of the very long-chain acyl-CoA synthetase family in bile acid synthesis and recycling","volume":"277","author":"Mihalik","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0225","doi-asserted-by":"crossref","first-page":"20573","DOI":"10.1074\/jbc.M700568200","article-title":"Fatty acid transport protein 4 is the principal very long chain fatty acyl-CoA synthetase in skin fibroblasts","volume":"282","author":"Jia","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0230","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/S0022-2275(20)34204-8","article-title":"Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts","volume":"39","author":"Verhoeven","year":"1998","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0235","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1096\/fj.06-6042com","article-title":"Analysis of the mouse and human acyl-CoA thioesterase (ACOT) gene clusters shows that convergent, functional evolution results in a reduced number of human peroxisomal ACOTs","volume":"20","author":"Hunt","year":"2006","journal-title":"FASEB J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0240","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1016\/S0014-5793(97)00856-9","article-title":"Formation of a 2-methyl-branched fatty aldehyde during peroxisomal alpha-oxidation","volume":"412","author":"Croes","year":"1997","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0245","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1152\/physrev.1966.46.2.323","article-title":"Peroxisomes (microbodies and related particles)","volume":"46","author":"De Duve","year":"1966","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0250","doi-asserted-by":"crossref","first-page":"482","DOI":"10.1083\/jcb.37.2.482","article-title":"The large-scale separation of peroxisomes, mitochondria, and lysosomes from the livers of rats injected with triton WR-1339. Improved isolation procedures, automated analysis, biochemical and morphological properties of fractions","volume":"37","author":"Leighton","year":"1968","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0255","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1083\/jcb.78.2.349","article-title":"Isolation of rat liver lysosomes by isopycnic centrifugation in a metrizamide gradient","volume":"78","author":"Wattiaux","year":"1978","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0260","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1016\/0003-2697(85)90250-7","article-title":"Purification of peroxisomes from livers of normal and clofibrate-treated mice","volume":"148","author":"Crane","year":"1985","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0265","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1111\/j.1432-1033.1985.tb08920.x","article-title":"Isolation and characterization of peroxisomes from the liver of normal untreated rats","volume":"149","author":"Volkl","year":"1985","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0270","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0003-2697(86)90323-4","article-title":"A rapid method for the isolation of peroxisomes from rat liver","volume":"159","author":"Ghosh","year":"1986","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0275","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1006\/abio.1994.1351","article-title":"The preparation of subcellular organelles from mouse liver in self-generated gradients of iodixanol","volume":"220","author":"Graham","year":"1994","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0280","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1006\/abio.1996.0194","article-title":"Iodixanol (Optiprep), an improved density gradient medium for the iso-osmotic isolation of rat liver peroxisomes","volume":"237","author":"Van Veldhoven","year":"1996","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0285","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1083\/jcb.26.1.219","article-title":"Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, d-amino acid oxidase, and catalase","volume":"26","author":"Baudhuin","year":"1965","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0290","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1007\/BF01869724","article-title":"Large cation-selective pores from rat liver peroxisomal membranes incorporated to planar lipid bilayers","volume":"94","author":"Labarca","year":"1986","journal-title":"J. Membr. Biol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0295","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0005-2736(89)90302-7","article-title":"Single-channel analysis of a large conductance channel in peroxisomes from rat liver","volume":"984","author":"Lemmens","year":"1989","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0300","doi-asserted-by":"crossref","first-page":"17559","DOI":"10.1074\/jbc.270.29.17559","article-title":"The membrane of leaf peroxisomes contains a porin-like channel","volume":"270","author":"Reumann","year":"1995","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0305","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1042\/bst0240754","article-title":"A specific porin is involved in the malate shuttle of leaf peroxisomes","volume":"24","author":"Reumann","year":"1996","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0310","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1046\/j.1432-1327.1998.2510359.x","article-title":"Permeability properties of the porin of spinach leaf peroxisomes","volume":"251","author":"Reumann","year":"1998","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0315","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1111\/j.1432-1033.1993.tb18353.x","article-title":"Permeability properties of peroxisomes in digitonin-permeabilized rat hepatocytes. Evidence for free permeability towards a variety of substrates","volume":"218","author":"Verleur","year":"1993","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0320","doi-asserted-by":"crossref","first-page":"1135","DOI":"10.1016\/0006-291X(90)90511-K","article-title":"Latency of the peroxisomal enzyme acyl-CoA: dihydroxyacetonephosphate acyltransferase in digitonin-permeabilized fibroblasts: the effect of ATP and ATPase inhibitors","volume":"170","author":"Wolvetang","year":"1990","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0325","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1016\/0167-4889(91)90074-8","article-title":"Factors influencing the latency of the peroxisomal enzyme dihydroxyacetone-phosphate acyltransferase (DHAP-AT) in permeabilized human skin fibroblasts","volume":"1095","author":"Wolvetang","year":"1991","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0330","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/0925-4439(93)90024-U","article-title":"Studies on mitochondrial oxidative phosphorylation in permeabilized human skin fibroblasts: application to mitochondrial encephalomyopathies","volume":"1181","author":"Wanders","year":"1993","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0335","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.bbalip.2003.12.010","article-title":"Functions and biosynthesis of plasmalogens in health and disease","volume":"1636","author":"Brites","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0340","doi-asserted-by":"crossref","first-page":"3480","DOI":"10.1002\/j.1460-2075.1995.tb07354.x","article-title":"The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions","volume":"14","author":"van Roermund","year":"1995","journal-title":"EMBO J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0345","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1093\/emboj\/17.3.677","article-title":"Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions","volume":"17","author":"van Roermund","year":"1998","journal-title":"EMBO J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0350","doi-asserted-by":"crossref","first-page":"3846","DOI":"10.1074\/jbc.271.7.3846","article-title":"l-Lactate dehydrogenase A4- and A3B isoforms are bona fide peroxisomal enzymes in rat liver. Evidence for involvement in intraperoxisomal NADH reoxidation","volume":"271","author":"Baumgart","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0355","doi-asserted-by":"crossref","first-page":"C1623","DOI":"10.1152\/ajpcell.00142.2004","article-title":"The behavior of peroxisomes in vitro: mammalian peroxisomes are osmotically sensitive particles","volume":"287","author":"Antonenkov","year":"2004","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0360","doi-asserted-by":"crossref","first-page":"5633","DOI":"10.1242\/jcs.01485","article-title":"The rat liver peroxisomal membrane forms a permeability barrier for cofactors but not for small metabolites in vitro","volume":"117","author":"Antonenkov","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0365","doi-asserted-by":"crossref","first-page":"2886","DOI":"10.1007\/s00018-005-5233-x","article-title":"Solute traffic across mammalian peroxisomal membrane\u2014single channel conductance monitoring reveals pore-forming activities in peroxisomes","volume":"62","author":"Antonenkov","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0370","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1111\/j.1742-4658.2009.06903.x","article-title":"Channel-forming activities of peroxisomal membrane proteins from the yeast Saccharomyces cerevisiae","volume":"276","author":"Grunau","year":"2009","journal-title":"FEBS J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0375","doi-asserted-by":"crossref","first-page":"e5090","DOI":"10.1371\/journal.pone.0005090","article-title":"Pxmp2 is a channel-forming protein in mammalian peroxisomal membrane","volume":"4","author":"Rokka","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0380","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1016\/S0006-291X(02)02663-3","article-title":"Identification of human PMP34 as a peroxisomal ATP transporter","volume":"299","author":"Visser","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0385","doi-asserted-by":"crossref","first-page":"4201","DOI":"10.1096\/fj.08-110866","article-title":"The human peroxisomal ABC half transporter ALDP functions as a homodimer and accepts acyl-CoA esters","volume":"22","author":"van Roermund","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0390","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1007\/s00424-003-1099-7","article-title":"The mitochondrial transporter family (SLC25): physiological and pathological implications","volume":"447","author":"Palmieri","year":"2004","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0395","doi-asserted-by":"crossref","first-page":"5049","DOI":"10.1093\/emboj\/20.18.5049","article-title":"Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter","volume":"20","author":"Palmieri","year":"2001","journal-title":"EMBO J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0400","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1146\/annurev.biochem.74.082803.133329","article-title":"Biochemistry of mammalian peroxisomes revisited","volume":"75","author":"Wanders","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0405","series-title":"Fasting Fuel Homeostasis Triggered by Defective Phytanic and Pristanic Acids Metabolism in the 70kDa Peroxisomal Membrane Protein (PMP70) Deficient Mice","first-page":"65","author":"Jimenez-Sanchez","year":"2000"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0410","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0140-6736(82)91780-9","article-title":"3-Methyladipate excretion in Refsum's disease","volume":"319","author":"Brenton","year":"1982","journal-title":"Lancet"},{"key":"10.1016\/j.bbalip.2011.06.006_bb0415","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1093\/clinchem\/29.3.434","article-title":"2,6-Dimethyloctanedioic acid\u2014a metabolite of phytanic acid in Refsum's disease","volume":"29","author":"Greter","year":"1983","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0420","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1194\/jlr.M300121-JLR200","article-title":"Metabolism of phytanic acid and 3-methyl-adipic acid excretion in patients with adult Refsum disease","volume":"44","author":"Wierzbicki","year":"2003","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0425","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1194\/jlr.M400064-JLR200","article-title":"Omega-hydroxylation of phytanic acid in rat liver microsomes: implications for Refsum disease","volume":"45","author":"Komen","year":"2004","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0430","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/j.ymgme.2005.02.005","article-title":"Characterization of phytanic acid omega-hydroxylation in human liver microsomes","volume":"85","author":"Komen","year":"2005","journal-title":"Mol. Gen. Metab."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0435","doi-asserted-by":"crossref","first-page":"3794","DOI":"10.1016\/j.febslet.2006.05.069","article-title":"Identification of the cytochrome P450 enzymes responsible for the omega-hydroxylation of phytanic acid","volume":"580","author":"Komen","year":"2006","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0440","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1042\/bj2940173","article-title":"Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs","volume":"294","author":"Bell","year":"1993","journal-title":"Biochem. J."},{"issue":"Pt 3","key":"10.1016\/j.bbalip.2011.06.006_bb0445","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1042\/bj3250741","article-title":"A novel murine P-450 gene, Cyp4a14, is part of a cluster of Cyp4a and Cyp4b, but not of CYP4F, genes in mouse and humans","volume":"325","author":"Heng","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0450","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1042\/BJ20061328","article-title":"Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation","volume":"403","author":"Muller","year":"2007","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0455","doi-asserted-by":"crossref","first-page":"17712","DOI":"10.1073\/pnas.0806066105","article-title":"Ataxia with loss of Purkinje cells in a mouse model for Refsum disease","volume":"105","author":"Ferdinandusse","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bbalip.2011.06.006_bb0460","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1046\/j.1432-1327.1999.00772.x","article-title":"The four murine peroxisomal ABC-transporter genes differ in constitutive, inducible and developmental expression","volume":"265","author":"Berger","year":"1999","journal-title":"Eur. J. Biochem."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198111000886?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198111000886?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,11,26]],"date-time":"2021-11-26T09:16:08Z","timestamp":1637918168000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198111000886"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,9]]},"references-count":92,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2011,9]]}},"alternative-id":["S1388198111000886"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2011.06.006","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2011,9]]}}}