{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T05:36:18Z","timestamp":1792647378112,"version":"4.5.0"},"reference-count":107,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T00:00:00Z","timestamp":1362096000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"crossref","award":["GM034496"],"award-info":[{"award-number":["GM034496"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Cancer Center (CORE) Support Grant","award":["CA21765"],"award-info":[{"award-number":["CA21765"]}]},{"DOI":"10.13039\/100012524","name":"American Lebanese Syrian Associated Charities","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012524","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2013,3]]},"DOI":"10.1016\/j.bbalip.2012.08.018","type":"journal-article","created":{"date-parts":[[2012,8,30]],"date-time":"2012-08-30T00:18:25Z","timestamp":1346285905000},"page":"495-502","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":188,"title":["Phosphatidic acid synthesis in bacteria"],"prefix":"10.1016","volume":"1831","author":[{"given":"Jiangwei","family":"Yao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles O.","family":"Rock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbalip.2012.08.018_bb0005","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1128\/JB.118.2.598-605.1974","article-title":"Mutants of Escherichia coli defective in membrane phospholipid synthesis: mapping of the structural gene for L-glycerol 3-phosphate dehydrogenase","volume":"118","author":"Cronan","year":"1974","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0010","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1099\/00221287-139-2-349","article-title":"The glpP and glpF genes of the glycerol regulon in Bacillus subtilis","volume":"139","author":"Beijer","year":"1993","journal-title":"J. Gen. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0015","doi-asserted-by":"crossref","first-page":"3316","DOI":"10.1016\/S0021-9258(18)93129-7","article-title":"Purification and regulatory properties of the biosynthetic L-glycerol-3-phophate dehydrogenase from Escherichia coli","volume":"244","author":"Kito","year":"1969","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0020","doi-asserted-by":"crossref","first-page":"2896","DOI":"10.1128\/jb.169.6.2896-2898.1987","article-title":"Acylation of glycerol 3-phosphate is the sole pathway of de novo phospholipid synthesis in Escherichia coli","volume":"169","author":"Ray","year":"1987","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0540","doi-asserted-by":"crossref","first-page":"3098","DOI":"10.1016\/S0021-9258(18)93858-5","article-title":"Active transport of L-glycerophosphate in Escherichia coli","volume":"239","author":"Hayashi","year":"1964","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0030","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1128\/JB.109.2.668-677.1972","article-title":"Effect of glycerol deprivation on the phospholipid metabolism of a glycerol auxotroph of Staphylococcus aureus","volume":"109","author":"Ray","year":"1972","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0035","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1128\/JB.144.1.462-464.1980","article-title":"The positional distribution of fatty acids in Escherichia coli phospholipids is not regulated by sn-glycerol 3-phosphate levels","volume":"144","author":"Goelz","year":"1980","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0040","doi-asserted-by":"crossref","first-page":"5899","DOI":"10.1128\/jb.177.20.5899-5905.1995","article-title":"Synthesis of sn-glycerol 3-phosphate, a key precursor of membrane lipids, in Bacillus subtilis","volume":"177","author":"Morbidoni","year":"1995","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0045","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1111\/j.1432-1033.1984.tb07923.x","article-title":"The role of lipoteichoic acid biosynthesis in membrane lipid metabolism of growing Staphylococcus aureus","volume":"138","author":"Koch","year":"1984","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0050","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1128\/JB.154.3.1110-1116.1983","article-title":"Biosynthesis of D-alanyl-lipoteichoic acid: role of diglyceride kinase in the synthesis of phosphatidylglycerol for chain elongation","volume":"154","author":"Taron","year":"1983","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0055","doi-asserted-by":"crossref","first-page":"15869","DOI":"10.1016\/S0021-9258(18)47669-7","article-title":"Purification and characterization of the repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K12","volume":"262","author":"Larson","year":"1987","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0060","doi-asserted-by":"crossref","first-page":"7080","DOI":"10.1128\/jb.178.24.7080-7089.1996","article-title":"Repressor for the sn-glycerol 3-phosphate regulon of Escherichia coli K-12: primary structure and identification of the DNA-binding domain","volume":"178","author":"Zeng","year":"1996","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0065","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1046\/j.1365-2958.1997.3991761.x","article-title":"Catabolite repression by glucose 6-phosphate, gluconate and lactose in Escherichia coli","volume":"24","author":"Hogema","year":"1997","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0070","doi-asserted-by":"crossref","first-page":"2393","DOI":"10.1128\/jb.176.8.2393-2397.1994","article-title":"Characterization of the interaction of the glp repressor of Escherichia coli K-12 with single and tandem glp operator variants","volume":"176","author":"Zhao","year":"1994","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0075","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1099\/00221287-144-2-449","article-title":"Antiterminator protein GlpP of Bacillus subtilis binds to glpD leader mRNA","volume":"144","author":"Glatz","year":"1998","journal-title":"Microbiology"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0080","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.resmic.2004.05.016","article-title":"Glycerol-3-phosphate transporter of Escherichia coli: structure, function and regulation","volume":"155","author":"Lemieux","year":"2004","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0085","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1046\/j.1365-2958.2000.01759.x","article-title":"Families of transmembrane sugar transport proteins","volume":"35","author":"Saier","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0090","doi-asserted-by":"crossref","first-page":"1054","DOI":"10.1128\/JB.161.3.1054-1058.1985","article-title":"Pi exchange mediated by the GlpT-dependent sn-glycerol-3-phosphate transport system in Escherichia coli","volume":"161","author":"Elvin","year":"1985","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0095","doi-asserted-by":"crossref","first-page":"i43","DOI":"10.1093\/jmicro\/54.suppl_1.i43","article-title":"Crystal structure and mechanism of GlpT, the glycerol-3-phosphate transporter from E. coli","volume":"54","author":"Lemieux","year":"2005","journal-title":"J. Electron Microsc."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0100","doi-asserted-by":"crossref","first-page":"616","DOI":"10.1126\/science.1087619","article-title":"Structure and mechanism of the glycerol-3-phosphate transporter from Escherichia coli","volume":"301","author":"Huang","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0105","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1126\/science.290.5491.481","article-title":"Structure of a glycerol-conducting channel and the basis for its selectivity","volume":"290","author":"Fu","year":"2000","journal-title":"Science"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0110","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S0959-440X(03)00114-3","article-title":"Glycerol facilitator GlpF and the associated aquaporin family of channels","volume":"13","author":"Stroud","year":"2003","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0115","doi-asserted-by":"crossref","first-page":"6122","DOI":"10.1016\/S0021-9258(18)42670-1","article-title":"Structure and regulation of the glpFK operon encoding glycerol diffusion facilitator and glycerol kinase of Escherichia coli K-12","volume":"267","author":"Weissenborn","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0120","doi-asserted-by":"crossref","first-page":"3922","DOI":"10.1016\/S0021-9258(19)43821-0","article-title":"Catalytic and allosteric properties of glycerol kinase from Escherichia coli","volume":"248","author":"Thorner","year":"1973","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0125","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1529\/biophysj.107.115105","article-title":"Diffusion of glycerol through Escherichia coli aquaglyceroporin GlpF","volume":"94","author":"H\u00e9nin","year":"2008","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0130","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1128\/JB.144.1.274-278.1980","article-title":"Substrate specificity and transport properties of the glycerol facilitator of Escherichia coli","volume":"144","author":"Heller","year":"1980","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0135","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1126\/science.153.3737.755","article-title":"Feedback inhibition of glycerol kinase, a catabolic enzyme in Escherichia coli","volume":"153","author":"Zwaig","year":"1966","journal-title":"Science"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0140","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1128\/JB.102.3.753-759.1970","article-title":"Glycerol kinase, the pacemaker for the dissimilation of glycerol in Escherichia coli","volume":"102","author":"Zwaig","year":"1970","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0145","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1128\/JB.90.5.1325-1329.1965","article-title":"Growth stasis by accumulated L-glycerophosphate in Escherichia coli","volume":"90","author":"Cozzarelli","year":"1965","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0150","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1006\/bbrc.2001.2022","article-title":"Forty years of fatty acid biosynthesis","volume":"292","author":"Rock","year":"2002","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0155","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1038\/nrmicro1839","article-title":"Membrane lipid homeostasis in bacteria","volume":"6","author":"Zhang","year":"2008","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0545","series-title":"Escherichia coli and Salmonella typhimurium: Cellular and Molecular Biology","first-page":"474","article-title":"Biosynthesis of membrane lipids","author":"Cronan","year":"1987"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0165","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0021-9258(19)70037-4","article-title":"Phospholipid synthesis in Escherichia coli. Characteristics of fatty acid transfer from acyl\u2013acyl carrier protein to sn-glycerol-3-phosphate","volume":"256","author":"Rock","year":"1981","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0170","doi-asserted-by":"crossref","first-page":"5835","DOI":"10.1016\/S0021-9258(19)41128-9","article-title":"Regulation of membrane lipid synthesis in Escherichia coli. Accumulation of free fatty acids of abnormal length during inhibition of phospholipid synthesis","volume":"250","author":"Cronan","year":"1975","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0175","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1016\/S0021-9258(19)85692-2","article-title":"\u03b2-Ketoacyl\u2013acyl carrier protein synthase II of Escherichia coli. Evidence for function in the thermal regulation of fatty acid synthesis","volume":"255","author":"Garwin","year":"1980","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0180","doi-asserted-by":"crossref","first-page":"10008","DOI":"10.1021\/bi060842w","article-title":"The soluble acyl\u2013acyl carrier protein synthetase of Vibrio harveyi B392 is a member of the medium chain acyl-CoA synthetase family","volume":"45","author":"Jiang","year":"2006","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0185","doi-asserted-by":"crossref","first-page":"15378","DOI":"10.1073\/pnas.1109208108","article-title":"Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors","volume":"108","author":"Parsons","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0190","doi-asserted-by":"crossref","first-page":"765","DOI":"10.1016\/j.molcel.2006.06.030","article-title":"Acyl-phosphates initiate membrane phospholipid synthesis in gram-positive pathogens","volume":"23","author":"Lu","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0195","doi-asserted-by":"crossref","first-page":"11339","DOI":"10.1074\/jbc.M700374200","article-title":"Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase","volume":"282","author":"Lu","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0200","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/S0021-9258(17)41438-4","article-title":"Synthesis and properties of the acyl phosphates of some higher fatty acids","volume":"162","author":"Lehninger","year":"1945","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0205","series-title":"Crystal structure of fatty acid\/phospholipid synthesis protein PlsX from Enterococcus faecalis","author":"Kim","year":"2008"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0210","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/prot.20541","article-title":"Structural analysis of a set of proteins resulting from a bacterial genomics project","volume":"60","author":"Badger","year":"2005","journal-title":"Proteins: Struct. Funct. Bioinform."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0215","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.1128\/JB.00602-07","article-title":"Coupling of fatty acid and phospholipid synthesis in Bacillus subtilis","volume":"189","author":"Paoletti","year":"2007","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0220","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/1471-2180-7-69","article-title":"Involvement of the YneS\/YgiH and PlsX proteins in phospholipid biosynthesis in both Bacillus subtilis and Escherichia coli","volume":"7","author":"Yoshimura","year":"2007","journal-title":"BMC Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0225","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1128\/JB.160.2.711-717.1984","article-title":"sn-Glycerol-3-phosphate auxotrophy of plsB strains of Escherichia coli: evidence that a second mutation, plsX, is required","volume":"160","author":"Larson","year":"1984","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0230","doi-asserted-by":"crossref","first-page":"14339","DOI":"10.1073\/pnas.2036282100","article-title":"Comprehensive transposon mutant library of Pseudomonas aeruginosa","volume":"100","author":"Jacobs","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0235","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1128\/MMBR.67.3.454-472.2003","article-title":"Transmembrane movement of exogenous long-chain fatty acids: proteins, enzymes, and vectorial esterification","volume":"67","author":"Black","year":"2003","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0240","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1046\/j.1365-2958.1998.00917.x","article-title":"FadR, transcriptional co-ordination of metabolic expediency","volume":"29","author":"Cronan","year":"1998","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0245","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1016\/S0163-7827(98)00022-8","article-title":"Molecular inroads into the regulation and metabolism of fatty acids, lessons from bacteria","volume":"38","author":"DiRusso","year":"1999","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0250","doi-asserted-by":"crossref","first-page":"5180","DOI":"10.1074\/jbc.M606831200","article-title":"Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation","volume":"282","author":"Matsuoka","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0255","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1128\/JB.183.4.1499-1503.2001","article-title":"Inhibition of Eschericia coli acetyl coenzyme A carboxylase by acyl\u2013acyl carrier protein","volume":"183","author":"Davis","year":"2001","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0260","doi-asserted-by":"crossref","first-page":"10996","DOI":"10.1074\/jbc.271.18.10996","article-title":"Inhibition of \u03b2-ketoacyl\u2013acyl carrier protein synthase III (FabH) by acyl\u2013acyl carrier protein in Escherichia coli","volume":"271","author":"Heath","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0265","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1111\/j.1365-2958.2005.04951.x","article-title":"Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae","volume":"59","author":"Lu","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0270","doi-asserted-by":"crossref","first-page":"15364","DOI":"10.1074\/jbc.C109.002410","article-title":"Acyl\u2013acyl carrier protein regulates transcription of fatty acid biosynthetic genes via the FabT repressor in Streptococcus pneumoniae","volume":"284","author":"Jerga","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0275","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1016\/S1534-5807(03)00123-0","article-title":"FapR, a bacterial transcription factor involved in global regulation of membrane lipid biosynthesis","volume":"4","author":"Schujman","year":"2003","journal-title":"Dev. Cell"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0280","doi-asserted-by":"crossref","first-page":"34880","DOI":"10.1074\/jbc.M109.068239","article-title":"Transcriptional regulation of membrane lipid homeostasis in Escherichia coli","volume":"284","author":"Zhu","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0285","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1073\/pnas.58.3.1168","article-title":"On the enzymatic synthesis of unsaturated fatty acids in Escherichia coli","volume":"58","author":"Kass","year":"1967","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0290","doi-asserted-by":"crossref","first-page":"29526","DOI":"10.1074\/jbc.M109.023440","article-title":"Escherichia coli unsaturated fatty acid synthesis","volume":"284","author":"Feng","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0295","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1365-2958.2007.05934.x","article-title":"A Pseudomonas aeruginosa transcription factor that senses fatty acid structure","volume":"66","author":"Zhang","year":"2007","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0300","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1111\/j.1365-2958.2006.05088.x","article-title":"Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa","volume":"60","author":"Zhu","year":"2006","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0305","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1128\/JB.00404-09","article-title":"DesT coordinates the expression of anaerobic and aerobic pathways for unsaturated fatty acid biosynthesis in Pseudomonas aeruginosa","volume":"192","author":"Subramanian","year":"2010","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0310","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1038\/nsmb.1847","article-title":"Transcriptional regulation of membrane lipid homeostasis","volume":"17","author":"Miller","year":"2010","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0315","doi-asserted-by":"crossref","first-page":"1867","DOI":"10.1194\/jlr.R800005-JLR200","article-title":"Acyltransferases in bacterial glycerophospholipid synthesis","volume":"49","author":"Zhang","year":"2008","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0320","doi-asserted-by":"crossref","first-page":"7153","DOI":"10.1016\/S0021-9258(19)40922-8","article-title":"Mutants of Escherichia coli defective in membrane phospholipid synthesis. Phenotypic suppression of sn-glycerol-3-phosphate acyltransferase Km mutants by loss of feedback inhibition of the biosynthetic sn-glycerol-3-phosphate dehydrogenase","volume":"250","author":"Bell","year":"1975","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0325","doi-asserted-by":"crossref","first-page":"7147","DOI":"10.1016\/S0021-9258(19)40921-6","article-title":"Mutants of Escherichia coli defective in membrane phospholipid synthesis: properties of wild type and Km defective sn-glycerol-3-phosphate acyltransfersae activities","volume":"250","author":"Bell","year":"1975","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0330","doi-asserted-by":"crossref","first-page":"10856","DOI":"10.1016\/S0021-9258(17)44354-7","article-title":"The DNA sequences encoding plsB and dgk loci of Escherichia coli","volume":"258","author":"Lightner","year":"1983","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0335","doi-asserted-by":"crossref","first-page":"9413","DOI":"10.1016\/S0021-9258(19)70578-X","article-title":"Membrane phospholipid synthesis in Escherichia coli: cloning of a structural gene (plsB) of the sn-glycerol-3-phosphate acyltransferase","volume":"255","author":"Lightner","year":"1980","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0340","doi-asserted-by":"crossref","first-page":"11151","DOI":"10.1016\/S0021-9258(19)68570-4","article-title":"Membrane phospholipid synthesis in Escherichia coli: purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase","volume":"256","author":"Green","year":"1981","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0345","doi-asserted-by":"crossref","first-page":"5764","DOI":"10.1021\/bi982805d","article-title":"Analysis of amino acid motifs diagnostic for the sn-glycerol-3-phosphate acyltransferase reaction","volume":"38","author":"Lewin","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0350","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0163-7827(03)00051-1","article-title":"Enzymes of triacylglycerol synthesis and their regulation","volume":"43","author":"Coleman","year":"2004","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0355","doi-asserted-by":"crossref","first-page":"1425","DOI":"10.1128\/JB.180.6.1425-1430.1998","article-title":"A conserved histidine is essential for glycerolipid acyltransferase catalysis","volume":"180","author":"Heath","year":"1998","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0360","doi-asserted-by":"crossref","first-page":"2161","DOI":"10.1007\/s00018-005-5160-x","article-title":"The catalytic triad of serine peptidases","volume":"62","author":"Polg\u00e1r","year":"2005","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0365","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/S0969-2126(01)00595-0","article-title":"Analysis of the structure, substrate specificity, and mechanism of squash glycerol-3-phosphate (1)-acyltransferase","volume":"9","author":"Turnbull","year":"2001","journal-title":"Structure"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0370","doi-asserted-by":"crossref","first-page":"1260","DOI":"10.1111\/j.1365-2958.2011.07641.x","article-title":"Antagonistic regulation of dgkA and plsB genes of phospholipid synthesis by multiple stress responses in Escherichia coli","volume":"80","author":"Wahl","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0375","doi-asserted-by":"crossref","first-page":"26584","DOI":"10.1016\/S0021-9258(18)47234-1","article-title":"Guanosine tetraphosphate inhibition of fatty acid and phospholipid synthesis in Escherichia coli is relieved by overexpression of glycerol-3-phosphate acyltransferase (plsB)","volume":"269","author":"Heath","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0380","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1016\/S0021-9258(18)53775-3","article-title":"Guanosine tetraphosphate inhibits protein synthesis in vivo","volume":"268","author":"Svitil","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0550","first-page":"1458","article-title":"The stringent response","volume":"vol. 2","author":"Cashel","year":"1996"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0390","doi-asserted-by":"crossref","first-page":"e2","DOI":"10.1371\/journal.pbio.0040002","article-title":"Conserved and variable functions of the \u03c3E stress response in related genomes","volume":"4","author":"Rhodius","year":"2005","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0395","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/0968-0004(90)90281-F","article-title":"The P-loop\u2014a common motif in ATP- and GTP-binding proteins","volume":"15","author":"Saraste","year":"1990","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0400","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1002\/cmdc.200800218","article-title":"Novel acyl phosphate mimics that target PlsY, an essential acyltransferase in gram-positive bacteria","volume":"3","author":"Grimes","year":"2008","journal-title":"ChemMedChem"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0405","doi-asserted-by":"crossref","first-page":"4678","DOI":"10.1073\/pnas.0730515100","article-title":"Essential Bacillus subtilis genes","volume":"100","author":"Kobayashi","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0410","doi-asserted-by":"crossref","first-page":"17215","DOI":"10.1016\/S0021-9258(17)44891-5","article-title":"Characterization of Escherichia coli cells deficient in 1-acyl-sn-glycerol-3-phosphate acyltransferase activity","volume":"265","author":"Coleman","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0415","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1007\/BF00280009","article-title":"Characterization of the Escherichia coli gene for 1-acyl-sn-glycerol-3-phosphate acyltransferase (plsC)","volume":"232","author":"Coleman","year":"1992","journal-title":"Mol. Gen. Genet."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0420","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1046\/j.1365-2958.1999.01404.x","article-title":"Multiple lysophosphatidic acid acyltransferases in Neisseria meningitidis","volume":"32","author":"Shih","year":"1999","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0425","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1111\/j.1365-2958.1995.mmi_18030401.x","article-title":"Membrane glycerophospholipid biosynthesis in Neisseria meningitidis and Neisseria gonorrhoeae: identification, characterization, and mutagenesis of a lysophosphatidic acid acyltransferase","volume":"18","author":"Swartley","year":"1995","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0430","doi-asserted-by":"crossref","first-page":"3071","DOI":"10.1099\/mic.0.27958-0","article-title":"Identification of two lysophosphatidic acid acyltransferase genes with overlapping function in Pseudomonas fluorescens","volume":"151","author":"Cullinane","year":"2005","journal-title":"Microbiology"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0435","doi-asserted-by":"crossref","first-page":"8564","DOI":"10.1128\/JB.01121-07","article-title":"Rhodobacter capsulatus OlsA is a bifunctional enzyme active in both ornithine lipid and phosphatidic acid biosynthesis","volume":"189","author":"Agun-Sunar","year":"2007","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0440","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/0005-2736(78)90157-8","article-title":"An estimate of the minimum amount of fluid lipid required for the growth of Escherichia coli","volume":"512","author":"Jackson","year":"1978","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0445","doi-asserted-by":"crossref","first-page":"4250","DOI":"10.1016\/S0021-9258(17)40257-2","article-title":"Relation of turnover of membrane phospholipids to synthesis of membrane-derived oligosaccharides of Escherichia coli","volume":"252","author":"Schulman","year":"1977","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0450","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1073\/pnas.79.4.1092","article-title":"Osmotic regulation and biosynthesis of membrane-derived oligosaccharides in Escherichia coli","volume":"79","author":"Kennedy","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0455","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1128\/JB.137.2.860-868.1979","article-title":"Diglyceride kinase mutants of Escherichia coli: inner membrane association of 1,2-diglyceride and its relation to synthesis of membrane-derived oligosaccharides","volume":"137","author":"Raetz","year":"1979","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0460","doi-asserted-by":"crossref","first-page":"3882","DOI":"10.1016\/S0021-9258(17)34773-7","article-title":"Neutral lipid accumulation in the membranes of Escherichia coli mutants lacking diglyceride kinase","volume":"253","author":"Raetz","year":"1978","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0465","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1126\/science.1171716","article-title":"Solution nuclear magnetic resonance structure of membrane-integral diacylglycerol kinase","volume":"324","author":"Van Horn","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0470","doi-asserted-by":"crossref","first-page":"1084","DOI":"10.1128\/JB.01092-07","article-title":"Transcription profiling of the stringent response in Escherichia coli","volume":"190","author":"Durfee","year":"2008","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0475","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1271\/bbb.68.1758","article-title":"A genome-wide view of the Escherichia coli BasS-BasR two-component system implicated in iron-responses","volume":"68","author":"Hagiwara","year":"2004","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0480","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1146\/annurev-biophys-050511-102330","article-title":"Prokaryotic diacylglycerol kinase and undecaprenol kinase","volume":"41","author":"Van Horn","year":"2011","journal-title":"Annu. Rev. Biophys."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0485","doi-asserted-by":"crossref","first-page":"21738","DOI":"10.1074\/jbc.M703536200","article-title":"Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis","volume":"282","author":"Jerga","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0490","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.str.2008.03.019","article-title":"Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases","volume":"16","author":"Miller","year":"2008","journal-title":"Structure"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0495","doi-asserted-by":"crossref","first-page":"7246","DOI":"10.1074\/jbc.M805962200","article-title":"Molecular determinants for interfacial binding and conformational change in a soluble diacylglycerol kinase","volume":"284","author":"Jerga","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0500","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1016\/0923-2508(90)90075-2","article-title":"Antibacterial activity of phenolic compounds and aromatic alcohols","volume":"141","author":"Lucchini","year":"1990","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0505","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1016\/0923-2508(90)90074-Z","article-title":"Antibacterial activity of phenethyl alcohol and resulting membrane alterations","volume":"141","author":"Corre","year":"1990","journal-title":"Res. Microbiol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0510","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/0005-2736(92)90202-W","article-title":"Effects of temperature variation and phenethyl alcohol addition on acyl chain order and lipid organization in Escherichia coli derived membrane systems. A 2H- and 31P-NMR study","volume":"1105","author":"Killian","year":"1992","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0515","doi-asserted-by":"crossref","first-page":"1359","DOI":"10.1128\/JB.127.3.1359-1369.1976","article-title":"Effects of phenethyl alcohol on Bacillus and Streptococcus","volume":"127","author":"Silva","year":"1976","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0520","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1128\/JB.109.1.162-168.1972","article-title":"Effects of phenethyl alcohol on phospholipid metabolism in Escherichia coli","volume":"109","author":"Nunn","year":"1972","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0525","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1021\/bi00625a008","article-title":"Fatty acid synthesis in Escherichia coli is indirectly inhibited by phenethyl alcohol","volume":"16","author":"Nunn","year":"1977","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbalip.2012.08.018_bb0530","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1128\/JB.130.2.620-628.1977","article-title":"Phenethyl alcohol inhibition of sn-glycerol 3-phosphate acylation in Escherichia coli","volume":"130","author":"Nunn","year":"1977","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bbalip.2012.08.018_bb0535","doi-asserted-by":"crossref","first-page":"4985","DOI":"10.1016\/j.bmc.2012.06.029","article-title":"Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria","volume":"20","author":"Cherian","year":"2012","journal-title":"Bioorg. Med. Chem."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198112001898?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198112001898?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,1,27]],"date-time":"2022-01-27T17:05:14Z","timestamp":1643303114000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198112001898"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":107,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2013,3]]}},"alternative-id":["S1388198112001898"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2012.08.018","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2013,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Phosphatidic acid synthesis in bacteria","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbalip.2012.08.018","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}