{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T04:08:29Z","timestamp":1790654909618,"version":"4.1.0"},"reference-count":73,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2018,6,11]],"date-time":"2018-06-11T00:00:00Z","timestamp":1528675200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","doi-asserted-by":"publisher","award":["R01HL115153"],"award-info":[{"award-number":["R01HL115153"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","doi-asserted-by":"publisher","award":["R01GM104427"],"award-info":[{"award-number":["R01GM104427"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute of the National Institutes of Health","doi-asserted-by":"publisher","award":["P01HL030086"],"award-info":[{"award-number":["P01HL030086"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006151","name":"Office of Science, Office of Basic Energy Sciences of the U.S. Department of Energy","doi-asserted-by":"publisher","award":["DE-AC02-05CH11231"],"award-info":[{"award-number":["DE-AC02-05CH11231"]}],"id":[{"id":"10.13039\/100006151","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2018,9]]},"DOI":"10.1016\/j.bbalip.2018.06.001","type":"journal-article","created":{"date-parts":[[2018,6,5]],"date-time":"2018-06-05T18:10:17Z","timestamp":1528222217000},"page":"1082-1094","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":28,"title":["Structural basis of the lipid transfer mechanism of phospholipid transfer protein (PLTP)"],"prefix":"10.1016","volume":"1863","author":[{"given":"Meng","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaobo","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John J.","family":"Albers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simona","family":"Vuletic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gang","family":"Ren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbalip.2018.06.001_bb0005","doi-asserted-by":"crossref","first-page":"3645","DOI":"10.1021\/bi962776b","article-title":"Molecular and macromolecular specificity of human plasma phospholipid transfer protein","volume":"36","author":"Rao","year":"1997","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0010","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1016\/S0022-2275(20)34314-5","article-title":"Plasma phospholipid transfer protein enhances transfer and exchange of phospholipids between very low density lipoproteins and high density lipoproteins during lipolysis","volume":"26","author":"Tall","year":"1985","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0015","doi-asserted-by":"crossref","first-page":"4032","DOI":"10.1016\/S0021-9258(18)53575-4","article-title":"Human plasma phospholipid transfer protein causes high density lipoprotein conversion","volume":"268","author":"Jauhiainen","year":"1993","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0020","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/01.hco.0000126979.41946.7e","article-title":"High-density lipoprotein metabolism and progression of atherosclerosis: new insights from the HDL Atherosclerosis Treatment Study","volume":"19","author":"Asztalos","year":"2004","journal-title":"Curr. Opin. Cardiol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0025","doi-asserted-by":"crossref","first-page":"11541","DOI":"10.1074\/jbc.M800117200","article-title":"An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux","volume":"283","author":"Oram","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0030","doi-asserted-by":"crossref","first-page":"1857","DOI":"10.1161\/01.ATV.0000094433.98445.7F","article-title":"High plasma phospholipid transfer protein levels as a risk factor for coronary artery disease","volume":"23","author":"Schlitt","year":"2003","journal-title":"Arterioscl. Throm. Vas."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0035","article-title":"High plasma phospholipid transfer protein (PLTP) levels as a risk factor for coronary artery disease","volume":"106","author":"Bickel","year":"2002","journal-title":"Circulation"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0040","doi-asserted-by":"crossref","DOI":"10.1186\/1743-7075-6-49","article-title":"Plasma PLTP activity is inversely associated with HDL-C levels","volume":"6","author":"Chen","year":"2009","journal-title":"Nutr. Metab."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0045","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1194\/jlr.M800414-JLR200","article-title":"PLTP activity is a risk factor for subsequent cardiovascular events in CAD patients under statin therapy: the AtheroGene Study","volume":"50","author":"Schlitt","year":"2009","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0050","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.atherosclerosis.2007.04.046","article-title":"Low phospholipid transfer protein (PLTP) is a risk factor for peripheral atherosclerosis","volume":"196","author":"Schgoer","year":"2008","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0055","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1161\/01.ATV.0000249721.96666.e5","article-title":"Macrophage phospholipid transfer protein deficiency and ApoE secretion - impact on mouse plasma cholesterol levels and atherosclerosis","volume":"27","author":"Liu","year":"2007","journal-title":"Arterioscl. Throm. Vas."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0060","doi-asserted-by":"crossref","first-page":"9388","DOI":"10.1016\/S0021-9258(17)37120-X","article-title":"Complete cDNA encoding human phospholipid transfer protein from human endothelial cells","volume":"269","author":"Day","year":"1994","journal-title":"J. Biol. Chem."},{"issue":"Suppl","key":"10.1016\/j.bbalip.2018.06.001_bb0065","doi-asserted-by":"crossref","first-page":"S201","DOI":"10.1194\/jlr.R800061-JLR200","article-title":"The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis","volume":"50","author":"Masson","year":"2009","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0070","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1042\/bst0310791","article-title":"Structure of human BPI (bactericidal\/permeability-increasing protein) and implications for related proteins","volume":"31","author":"Beamer","year":"2003","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0075","doi-asserted-by":"crossref","first-page":"29477","DOI":"10.1074\/jbc.M003523200","article-title":"Cholesteryl ester transfer protein and phospholipid transfer protein have nonoverlapping functions in vivo","volume":"275","author":"Kawano","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0080","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1194\/jlr.M056333","article-title":"Modification of CETP function by changing its substrate preference: a new paradigm for CETP drug design","volume":"56","author":"Morton","year":"2015","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0085","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1172\/JCI5578","article-title":"Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels","volume":"103","author":"Jiang","year":"1999","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0090","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1074\/jbc.272.7.3953","article-title":"Evidence that cholesteryl ester transfer protein-mediated reductions in reconstituted high density lipoprotein size involve particle fusion","volume":"272","author":"Rye","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0095","doi-asserted-by":"crossref","first-page":"26898","DOI":"10.1074\/jbc.M010708200","article-title":"The mechanism of the remodeling of high density lipoproteins by phospholipid transfer protein","volume":"276","author":"Settasatian","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0100","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1074\/jbc.272.7.3953","article-title":"Evidence that cholesteryl ester transfer protein-mediated reductions in reconstituted high density lipoprotein size involve particle fusion","volume":"272","author":"Rye","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0105","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1038\/nchembio.796","article-title":"Structural basis of transfer between lipoproteins by cholesteryl ester transfer protein","volume":"8","author":"Zhang","year":"2012","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0110","doi-asserted-by":"crossref","first-page":"8741","DOI":"10.1038\/srep08741","article-title":"HDL surface lipids mediate CETP binding as revealed by electron microscopy and molecular dynamics simulation","volume":"5","author":"Zhang","year":"2015","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0115","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1016\/j.bbalip.2017.09.004","article-title":"Assessing the mechanisms of cholesteryl ester transfer protein inhibitors","volume":"1862","author":"Zhang","year":"2017","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0120","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jsb.2016.02.016","article-title":"Cholesteryl ester transfer between lipoproteins does not require a ternary tunnel complex with CETP","volume":"194","author":"Lauer","year":"2016","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0125","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1016\/S0022-2275(20)33516-1","article-title":"Structure and phospholipid transfer activity of human PLTP: analysis by molecular modeling and site-directed mutagenesis","volume":"40","author":"Huuskonen","year":"1999","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0130","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1016\/S0959-440X(98)80118-8","article-title":"The implications of the structure of the bactericidal\/permeability-increasing protein on the lipid-transfer function of the cholesteryl ester transfer protein","volume":"8","author":"Bruce","year":"1998","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0135","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1002\/pro.5560070408","article-title":"The BPI\/LBP family of proteins: a structural analysis of conserved regions","volume":"7","author":"Beamer","year":"1998","journal-title":"Protein Sci."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0140","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1038\/nsmb1197","article-title":"Crystal structure of cholesteryl ester transfer protein reveals a long tunnel and four bound lipid molecules","volume":"14","author":"Qiu","year":"2007","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0145","doi-asserted-by":"crossref","first-page":"1328","DOI":"10.1016\/S0022-2275(20)38039-1","article-title":"Kinetics of plasma protein-catalyzed exchange of phosphatidylcholine and cholesteryl ester between plasma lipoproteins","volume":"23","author":"Ihm","year":"1982","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0150","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0022-2275(20)39830-8","article-title":"Kinetic studies of the transfer of esterified cholesterol between human plasma low and high density lipoproteins","volume":"21","author":"Barter","year":"1980","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0155","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1073\/pnas.0908004107","article-title":"Model of human low-density lipoprotein and bound receptor based on cryoEM","volume":"107","author":"Ren","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0160","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1194\/jlr.M070375","article-title":"Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography1","volume":"57","author":"Yu","year":"2016","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0165","doi-asserted-by":"crossref","first-page":"1827","DOI":"10.1016\/S0022-2275(20)34899-9","article-title":"Structural heterogeneity of apoB-containing serum lipoproteins visualized using cryo-electron microscopy","volume":"40","author":"van Antwerpen","year":"1999","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0170","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1194\/jlr.D010959","article-title":"Morphology and structure of lipoproteins revealed by an optimized negative-staining protocol of electron microscopy","volume":"52","author":"Zhang","year":"2011","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0175","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1002\/pro.101","article-title":"Apolipoprotein AI tertiary structures determine stability and phospholipid-binding activity of discoidal high-density lipoprotein particles of different sizes","volume":"18","author":"Chen","year":"2009","journal-title":"Protein Sci."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0180","doi-asserted-by":"crossref","first-page":"12176","DOI":"10.1073\/pnas.0803626105","article-title":"Structure of apolipoprotein A-I in spherical high density lipoproteins of different sizes","volume":"105","author":"Silva","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0185","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1194\/jlr.D002493","article-title":"An optimized negative-staining protocol of electron microscopy for apoE4 POPC lipoprotein","volume":"51","author":"Zhang","year":"2010","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0190","doi-asserted-by":"crossref","first-page":"2150","DOI":"10.1016\/j.bbagen.2012.09.016","article-title":"Optimized negative-staining electron microscopy for lipoprotein studies","volume":"1830","author":"Zhang","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0195","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1038\/srep01089","article-title":"Peptide-conjugation induced conformational changes in human IgG1 observed by optimized negative-staining and individual-particle electron tomography","volume":"3","author":"Tong","year":"2013","journal-title":"Sci. Rep. Uk"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0200","article-title":"Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography","volume":"7","author":"Zhang","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0205","first-page":"e51087","article-title":"Optimized negative staining: a high-throughput protocol for examining small and asymmetric protein structure by electron microscopy","author":"Rames","year":"2014","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0210","article-title":"IPET and FETR: experimental approach for studying molecular structure dynamics by cryo-electron tomography of a single-molecule structure","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0215","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1006\/jsbi.1999.4174","article-title":"EMAN: semiautomated software for high-resolution single-particle reconstructions","volume":"128","author":"Ludtke","year":"1999","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0220","doi-asserted-by":"crossref","first-page":"5908","DOI":"10.1074\/jbc.M008420200","article-title":"A hydrophobic cluster at the surface of the human plasma phospholipid transfer protein is critical for activity on high density lipoproteins","volume":"276","author":"Desrumaux","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0225","doi-asserted-by":"crossref","first-page":"11541","DOI":"10.1074\/jbc.M800117200","article-title":"An amphipathic helical region of the N-terminal barrel of phospholipid transfer protein is critical for ABCA1-dependent cholesterol efflux","volume":"283","author":"Oram","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0230","doi-asserted-by":"crossref","first-page":"19462","DOI":"10.1074\/jbc.M116.744623","article-title":"Structural plasticity of cholesteryl ester transfer protein assists the lipid transfer activity","volume":"291","author":"Chirasani","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0235","doi-asserted-by":"crossref","first-page":"1605","DOI":"10.1002\/jcc.20084","article-title":"UCSF chimera\u2013a visualization system for exploratory research and analysis","volume":"25","author":"Pettersen","year":"2004","journal-title":"J. Comput. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0240","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1006\/bbrc.1998.9162","article-title":"Remodeling of HDL by phospholipid transfer protein: demonstration of particle fusion by 1H NMR spectroscopy","volume":"249","author":"Korhonen","year":"1998","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0245","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1016\/0005-2760(82)90271-5","article-title":"Transfer of [14C]phosphatidylcholine between liposomes and human plasma high density lipoprotein. Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay","volume":"712","author":"Damen","year":"1982","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0250","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/0005-2760(96)00082-3","article-title":"Plasma phospholipid mass transfer rate: relationship to plasma phospholipid and cholesteryl ester transfer activities and lipid parameters","volume":"1303","author":"Cheung","year":"1996","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0255","doi-asserted-by":"crossref","first-page":"1651","DOI":"10.1016\/S0022-2275(20)31998-2","article-title":"Distribution of phospholipid transfer protein in human plasma: presence of two forms of phospholipid transfer protein, one catalytically active and the other inactive","volume":"41","author":"Oka","year":"2000","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0260","doi-asserted-by":"crossref","first-page":"2303","DOI":"10.1194\/jlr.M400250-JLR200","article-title":"Active and low-active forms of serum phospholipid transfer protein in a normal Finnish population sample","volume":"45","author":"Janis","year":"2004","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0265","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.bbalip.2011.02.001","article-title":"Different phospholipid transfer protein complexes contribute to the variation in plasma PLTP specific activity","volume":"1811","author":"Cheung","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0270","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1016\/S0022-2275(20)34211-5","article-title":"Binding of phospholipid transfer protein (PLTP) to apolipoproteins A-I and A-II: location of a PLTP binding domain in the amino terminal region of apoA-I","volume":"39","author":"Pussinen","year":"1998","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb8000","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/S0022-2275(20)37271-0","article-title":"ApoA-II\/apoA-I molar ratio in the HDL particle influences phospholipid transfer protein-mediated HDL interconversion","volume":"38","author":"Pussinen","year":"1997","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb9000","first-page":"347","article-title":"Displacement of the Human Apoprotein A-I by the Human Apoprotein A-II from Complexes of (Apoprotein A-I)-Phosphatidylcholine-Cholesterol","volume":"117","author":"Rosseneu","year":"1981","journal-title":"FEBS J."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0285","doi-asserted-by":"crossref","first-page":"1312","DOI":"10.1021\/bi0621866","article-title":"Interfacial and lipid transfer properties of human phospholipid transfer protein: implications for the transfer mechanism of phospholipids","volume":"46","author":"Setala","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0290","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.bbalip.2011.06.013","article-title":"Role of plasma phospholipid transfer protein in lipid and lipoprotein metabolism","volume":"1821","author":"Albers","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0295","doi-asserted-by":"crossref","first-page":"1879","DOI":"10.1194\/jlr.M070375","article-title":"Polyhedral 3D structure of human plasma very low density lipoproteins by individual particle cryo-electron tomography","volume":"57","author":"Yu","year":"2016","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0300","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/0005-2760(95)00091-P","article-title":"Functional expression of human and mouse plasma phospholipid transfer protein: effect of recombinant and plasma PLTP on HDL subspecies","volume":"1258","author":"Albers","year":"1995","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0305","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/j.bbapap.2011.04.004","article-title":"Impact of site-specific N-glycosylation on cellular secretion, activity and specific activity of the plasma phospholipid transfer protein","volume":"1814","author":"Albers","year":"2011","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0310","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/s12265-011-9340-9","article-title":"Comparison of lipoprotein separation and lipid analysis methodologies for human and cynomolgus monkey plasma samples","volume":"5","author":"Han","year":"2012","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0315","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1373\/clinchem.2007.100586","article-title":"Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis","volume":"54","author":"Caulfield","year":"2008","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0320","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1251\/bpo70","article-title":"Negative staining and image classification - powerful tools in modern electron microscopy","volume":"6","author":"Ohi","year":"2004","journal-title":"Biol. Proced. Online"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0325","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jsb.2006.05.004","article-title":"FREALIGN: high-resolution refinement of single particle structures","volume":"157","author":"Grigorieff","year":"2007","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0330","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1006\/jsbi.1996.0030","article-title":"SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields","volume":"116","author":"Frank","year":"1996","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0335","article-title":"Fully mechanically controlled automated electron microscopic tomography","volume":"6","author":"Liu","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0340","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1006\/jsbi.1996.0013","article-title":"Computer visualization of three-dimensional image data using IMOD","volume":"116","author":"Kremer","year":"1996","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0345","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jsb.2006.05.004","article-title":"FREALIGN: high-resolution refinement of single particle structures","volume":"157","author":"Grigorieff","year":"2007","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0350","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.ultramic.2006.02.004","article-title":"CTF determination and correction in electron cryotomography","volume":"106","author":"Fernandez","year":"2006","journal-title":"Ultramicroscopy"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0355","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jsb.2006.05.009","article-title":"EMAN2: an extensible image processing suite for electron microscopy","volume":"157","author":"Tang","year":"2007","journal-title":"J. Struct. Biol."},{"key":"10.1016\/j.bbalip.2018.06.001_bb0360","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1038\/386088a0","article-title":"Determination of the fold of the core protein of hepatitis B virus by electron cryomicroscopy","volume":"386","author":"Bottcher","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbalip.2018.06.001_bb0365","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1107\/S0907444900005163","article-title":"The protein content in crystals and packing coefficients in different space groups","volume":"56","author":"Andersson","year":"2000","journal-title":"Acta Crystallogr. D Biol. Crystallogr."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198118301227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198118301227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T09:59:31Z","timestamp":1761386371000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198118301227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,9]]},"references-count":73,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9]]}},"alternative-id":["S1388198118301227"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2018.06.001","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2018,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Structural basis of the lipid transfer mechanism of phospholipid transfer protein (PLTP)","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbalip.2018.06.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}]}}