{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:27:09Z","timestamp":1792189629550,"version":"4.4.0"},"reference-count":40,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023M732655"],"award-info":[{"award-number":["2023M732655"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bbalip.2024.159581","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T17:50:53Z","timestamp":1732125053000},"page":"159581","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Role of USF1 in activating CYBA transcription and influencing NADPH-ROS-mediated oxidative stress and lipid accumulation in non-alcoholic fatty liver disease"],"prefix":"10.1016","volume":"1870","author":[{"given":"Shaohua","family":"Zhuang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinjin","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwei","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanfu","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuanyong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"20","key":"10.1016\/j.bbalip.2024.159581_bb0005","doi-asserted-by":"crossref","DOI":"10.3390\/ijms242015272","article-title":"Gut microbiota patterns in patients with non-alcoholic fatty liver disease: a comprehensive assessment using three analysis methods","volume":"24","author":"Korobeinikova","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.bbalip.2024.159581_bb0010","article-title":"Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis","volume":"1867","author":"Hughey","year":"2022","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbalip.2024.159581_bb0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.molmet.2021.101238","article-title":"Metabolic-associated fatty liver disease and lipoprotein metabolism","volume":"50","author":"Heeren","year":"2021","journal-title":"Mol. Metab."},{"issue":"11","key":"10.1016\/j.bbalip.2024.159581_bb0020","doi-asserted-by":"crossref","first-page":"4877","DOI":"10.1021\/acsabm.3c00612","article-title":"Targeted delivery of celastrol via chondroitin sulfate derived hybrid micelles for alleviating symptoms in nonalcoholic fatty liver disease","volume":"6","author":"Pan","year":"2023","journal-title":"ACS Appl. Bio Mater."},{"key":"10.1016\/j.bbalip.2024.159581_bb0025","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.freeradbiomed.2020.12.449","article-title":"Role of necroptosis in chronic hepatic inflammation and fibrosis in a mouse model of increased oxidative stress","volume":"164","author":"Mohammed","year":"2021","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbalip.2024.159581_bb0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.bmc.2023.117274","article-title":"Identification of a Noxo1 inhibitor by addition of a polyethylene glycol chain","volume":"85","author":"Mokhtarpour","year":"2023","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bbalip.2024.159581_bb0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165821","article-title":"Altered generation pattern of reactive oxygen species triggering DNA and plasma membrane damages to human liver cells treated with arsenite","volume":"900","author":"Zhang","year":"2023","journal-title":"Sci. Total Environ."},{"issue":"5","key":"10.1016\/j.bbalip.2024.159581_bb0040","doi-asserted-by":"crossref","first-page":"1090","DOI":"10.1080\/15548627.2021.1969765","article-title":"Macrophages target listeria monocytogenes by two discrete non-canonical autophagy pathways","volume":"18","author":"Gluschko","year":"2022","journal-title":"Autophagy"},{"issue":"4","key":"10.1016\/j.bbalip.2024.159581_bb0045","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.hbpd.2018.06.005","article-title":"Association between the CYBA and NOX4 genes of NADPH oxidase and its relationship with metabolic syndrome in non-alcoholic fatty liver disease in Brazilian population","volume":"17","author":"Rabelo","year":"2018","journal-title":"Hepatobiliary Pancreat. Dis. Int."},{"issue":"6","key":"10.1016\/j.bbalip.2024.159581_bb0050","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1016\/j.coph.2010.08.004","article-title":"Insulin signaling in fatty acid and fat synthesis: a transcriptional perspective","volume":"10","author":"Wong","year":"2010","journal-title":"Curr. Opin. Pharmacol."},{"issue":"16","key":"10.1016\/j.bbalip.2024.159581_bb0055","doi-asserted-by":"crossref","first-page":"2725","DOI":"10.1002\/1873-3468.13203","article-title":"Upstream stimulating factor 1 suppresses autophagy and hepatic lipid droplet catabolism by activating mTOR","volume":"592","author":"Guo","year":"2018","journal-title":"FEBS Lett."},{"issue":"4","key":"10.1016\/j.bbalip.2024.159581_bb0060","doi-asserted-by":"crossref","first-page":"525","DOI":"10.2337\/dbi18-0032","article-title":"Epigenetic regulation of hepatic lipogenesis: role in hepatosteatosis and diabetes","volume":"69","author":"Viscarra","year":"2020","journal-title":"Diabetes"},{"issue":"1","key":"10.1016\/j.bbalip.2024.159581_bb0065","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1186\/s12967-022-03540-2","article-title":"Reducing VEGFB accelerates NAFLD and insulin resistance in mice via inhibiting AMPK signaling pathway","volume":"20","author":"Li","year":"2022","journal-title":"J. Transl. Med."},{"key":"10.1016\/j.bbalip.2024.159581_bb0070","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/j.freeradbiomed.2017.09.016","article-title":"Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4\/NOX1-mediated regulation of superoxide","volume":"113","author":"Long","year":"2017","journal-title":"Free Radic. Biol. Med."},{"issue":"4","key":"10.1016\/j.bbalip.2024.159581_bb0075","article-title":"Identification of hub genes and biological mechanisms associated with non-alcoholic fatty liver disease and triple-negative breast cancer","volume":"13","author":"Zhu","year":"2023","journal-title":"Life (Basel)"},{"issue":"6","key":"10.1016\/j.bbalip.2024.159581_bb0080","doi-asserted-by":"crossref","first-page":"3626","DOI":"10.1007\/s12035-015-9294-z","article-title":"PPAR-gamma ameliorates neuronal apoptosis and ischemic brain injury via suppressing NF-kappaB-driven p22phox transcription","volume":"53","author":"Wu","year":"2016","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.bbalip.2024.159581_bb0085","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2022.899731","article-title":"Parathyroid hormone alleviates non-alcoholic liver steatosis via activating the hepatic cAMP\/PKA\/CREB pathway","volume":"13","author":"Feng","year":"2022","journal-title":"Front. Endocrinol. (Lausanne)"},{"issue":"3","key":"10.1016\/j.bbalip.2024.159581_bb0090","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1016\/j.celrep.2013.02.009","article-title":"Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis","volume":"3","author":"Jin","year":"2013","journal-title":"Cell Rep."},{"issue":"2","key":"10.1016\/j.bbalip.2024.159581_bb0095","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1097\/ICO.0000000000003111","article-title":"Cryopreserved amniotic membrane using the TissueTuck technique: a sutureless approach for pterygium surgery","volume":"42","author":"Desai","year":"2023","journal-title":"Cornea"},{"issue":"4","key":"10.1016\/j.bbalip.2024.159581_bb0100","first-page":"1905","article-title":"MicroRNA-199a-3p attenuates hepatic lipogenesis by targeting Sp1","volume":"9","author":"Cheng","year":"2017","journal-title":"Am. J. Transl. Res."},{"issue":"1","key":"10.1016\/j.bbalip.2024.159581_bb0105","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1186\/s12929-014-0087-x","article-title":"Flavonoid ingredients of Ginkgo biloba leaf extract regulate lipid metabolism through Sp1-mediated carnitine palmitoyltranferase 1A up-regulation","volume":"21","author":"Wei","year":"2014","journal-title":"J. Biomed. Sci."},{"key":"10.1016\/j.bbalip.2024.159581_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.bcp.2021.114420","article-title":"Prenatal dexamethasone exposure induces nonalcoholic fatty liver disease in male rat offspring via the miR-122\/YY1\/ACE2-MAS1 pathway","volume":"185","author":"Liu","year":"2021","journal-title":"Biochem. Pharmacol."},{"issue":"9","key":"10.1016\/j.bbalip.2024.159581_bb0115","doi-asserted-by":"crossref","first-page":"13033","DOI":"10.1096\/fj.202000546R","article-title":"Betulinic acid improves nonalcoholic fatty liver disease through YY1\/FAS signaling pathway","volume":"34","author":"Mu","year":"2020","journal-title":"FASEB J."},{"issue":"1","key":"10.1016\/j.bbalip.2024.159581_bb0120","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1038\/s41467-018-03072-8","article-title":"Ultraconserved element uc.372 drives hepatic lipid accumulation by suppressing miR-195\/miR4668 maturation","volume":"9","author":"Guo","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbalip.2024.159581_bb0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbi.2020.109199","article-title":"High fat diet-triggered non-alcoholic fatty liver disease: a review of proposed mechanisms","volume":"330","author":"Lian","year":"2020","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.bbalip.2024.159581_bb0130","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2021.704704","article-title":"Comprehensive analysis of NAFLD and the therapeutic target identified","volume":"9","author":"Wen","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"7","key":"10.1016\/j.bbalip.2024.159581_bb0135","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1002\/humu.21029","article-title":"Three common polymorphisms in the CYBA gene form a haplotype associated with decreased ROS generation","volume":"30","author":"Bedard","year":"2009","journal-title":"Hum. Mutat."},{"issue":"4","key":"10.1016\/j.bbalip.2024.159581_bb0140","doi-asserted-by":"crossref","first-page":"1675","DOI":"10.1007\/s00464-017-5846-9","article-title":"How bariatric surgery affects liver volume and fat density in NAFLD patients","volume":"32","author":"Luo","year":"2018","journal-title":"Surg. Endosc."},{"issue":"2","key":"10.1016\/j.bbalip.2024.159581_bb0145","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1007\/s00431-021-04243-4","article-title":"Vitamin D and nonalcoholic fatty liver disease in children: a randomized controlled clinical trial","volume":"181","author":"El Amrousy","year":"2022","journal-title":"Eur. J. Pediatr."},{"key":"10.1016\/j.bbalip.2024.159581_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.metabol.2019.153994","article-title":"Fibroblast growth factor 21 in non-alcoholic fatty liver disease","volume":"101","author":"Tucker","year":"2019","journal-title":"Metabolism"},{"issue":"5","key":"10.1016\/j.bbalip.2024.159581_bb0155","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1007\/s40265-020-01278-z","article-title":"Glucokinase activators for type 2 diabetes: challenges and future developments","volume":"80","author":"Toulis","year":"2020","journal-title":"Drugs"},{"issue":"5","key":"10.1016\/j.bbalip.2024.159581_bb0160","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1177\/1708538120922700","article-title":"Potential genes and pathways along with immune cells infiltration in the progression of atherosclerosis identified via microarray gene expression dataset re-analysis","volume":"28","author":"Xu","year":"2020","journal-title":"Vascular"},{"key":"10.1016\/j.bbalip.2024.159581_bb0165","doi-asserted-by":"crossref","DOI":"10.1155\/2018\/7019573","article-title":"Treatment of NASH with antioxidant therapy: beneficial effect of red cabbage on type 2 diabetic rats","volume":"2018","author":"Dal","year":"2018","journal-title":"Oxid. Med. Cell. Longev."},{"issue":"21","key":"10.1016\/j.bbalip.2024.159581_bb0170","doi-asserted-by":"crossref","first-page":"5414","DOI":"10.1111\/jcmm.17564","article-title":"Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function of HF rats induced by isoproterenol via suppressing NADPH\/ROS\/ER stress","volume":"26","author":"Ni","year":"2022","journal-title":"J. Cell. Mol. Med."},{"key":"10.1016\/j.bbalip.2024.159581_bb0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.trim.2021.101434","article-title":"Diphenyleneiodonium ameliorates acute liver rejection during transplantation by inhibiting neutrophil extracellular traps formation in vivo","volume":"68","author":"Liu","year":"2021","journal-title":"Transpl. Immunol."},{"issue":"1","key":"10.1016\/j.bbalip.2024.159581_bb0180","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1186\/s10020-024-00798-8","article-title":"USF1 transcriptionally activates USP14 to drive atherosclerosis by promoting EndMT through NLRC5\/Smad2\/3 axis","volume":"30","author":"Zhang","year":"2024","journal-title":"Mol. Med."},{"key":"10.1016\/j.bbalip.2024.159581_bb0185","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.730813","article-title":"Proteomic and biological analysis of the effects of metformin senomorphics on the mesenchymal stromal cells","volume":"9","author":"Acar","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"issue":"5","key":"10.1016\/j.bbalip.2024.159581_bb0190","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1093\/cvr\/cvac193","article-title":"Endothelial PTP4A1 mitigates vascular inflammation via USF1\/A20 axis-mediated NF-kappaB inactivation","volume":"119","author":"Cho","year":"2023","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbalip.2024.159581_bb0195","article-title":"Effects of USF1 SNPs and SNP-environment interactions on serum lipid profiles and the risk of early-onset coronary artery disease in the Chinese population","volume":"9","author":"Zheng","year":"2022","journal-title":"Front. Cardiovasc. Med."},{"issue":"1","key":"10.1016\/j.bbalip.2024.159581_bb0200","article-title":"Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease","volume":"11","author":"Ma","year":"2021","journal-title":"Antioxidants (Basel)"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198124001318?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198124001318?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T01:03:43Z","timestamp":1738458223000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198124001318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["S1388198124001318"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2024.159581","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Role of USF1 in activating CYBA transcription and influencing NADPH-ROS-mediated oxidative stress and lipid accumulation in non-alcoholic fatty liver disease","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbalip.2024.159581","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"159581"}}