{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T07:06:06Z","timestamp":1784185566576,"version":"3.55.0"},"reference-count":22,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,10]],"date-time":"2026-06-10T00:00:00Z","timestamp":1781049600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004281","name":"National Science Centre Poland","doi-asserted-by":"publisher","award":["2023\/51\/D\/ST4\/01686"],"award-info":[{"award-number":["2023\/51\/D\/ST4\/01686"]}],"id":[{"id":"10.13039\/501100004281","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.bbalip.2026.159756","type":"journal-article","created":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T00:13:24Z","timestamp":1781136804000},"page":"159756","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lipid droplet isolation as a novel platform for spectroscopic investigation of cargo modifications"],"prefix":"10.1016","volume":"1871","author":[{"given":"Karolina","family":"Chrab\u0105szcz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Panek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarzyna","family":"Pogoda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbalip.2026.159756_bb0005","doi-asserted-by":"crossref","first-page":"2610","DOI":"10.1111\/j.1742-4658.2012.08644.x","article-title":"Lipid metabolism in cancer","volume":"279","author":"Santos","year":"2012","journal-title":"FEBS J."},{"key":"10.1016\/j.bbalip.2026.159756_bb0010","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a040576","article-title":"Lipid metabolism","volume":"13","author":"Chandel","year":"2021","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.bbalip.2026.159756_bb0015","doi-asserted-by":"crossref","first-page":"1909","DOI":"10.1007\/s00018-018-2765-4","article-title":"Lipids in the cell: organisation regulates function","volume":"75","author":"Santos","year":"2018","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbalip.2026.159756_bb0020","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72943","article-title":"Lipid droplets and ferritin heavy chain: a devilish liaison in human cancer cell radioresistance","volume":"10","author":"Tirinato","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.bbalip.2026.159756_bb0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.jpha.2024.101136","article-title":"Raman analysis of lipids in cells: current applications and future prospects","volume":"15","author":"Zhou","year":"2025","journal-title":"J. Pharm. Anal."},{"key":"10.1016\/j.bbalip.2026.159756_bb0030","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.addr.2020.07.013","article-title":"Lipids and cancer: emerging roles in pathogenesis, diagnosis and therapeutic intervention","volume":"159","author":"Butler","year":"2020","journal-title":"Adv. Drug Deliv. Rev."},{"key":"10.1016\/j.bbalip.2026.159756_bb0035","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2024.1470269","article-title":"Lipidome analyses reveal radiation induced remodeling of glycerophospholipid unsaturation in lung tumor","volume":"15","author":"He","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bbalip.2026.159756_bb0040","doi-asserted-by":"crossref","DOI":"10.1186\/s13008-024-00116-y","article-title":"Cancer radioresistance is characterized by a differential lipid droplet content along the cell cycle","volume":"19","author":"Pagliari","year":"2024","journal-title":"Cell Div"},{"key":"10.1016\/j.bbalip.2026.159756_bb0045","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s42003-021-02679-w","article-title":"Raman microscopy-based quantification of the physical properties of intracellular lipids","volume":"4","author":"Uematsu","year":"2021","journal-title":"Commun. Biol."},{"issue":"1","key":"10.1016\/j.bbalip.2026.159756_bb0050","doi-asserted-by":"crossref","first-page":"9130","DOI":"10.1038\/s41467-025-64604-7","article-title":"Subcellular mass spectrometry imaging of lipids and nucleotides using transmission geometry ambient laser desorption and plasma ionisation","volume":"16","author":"Young","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbalip.2026.159756_bb0055","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1007\/978-1-4939-9488-5_17","article-title":"Detection and quantification of lipid droplets in differentiated human podocytes","volume":"1996","author":"Mallela","year":"2019","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bbalip.2026.159756_bb0060","doi-asserted-by":"crossref","first-page":"16374","DOI":"10.1021\/acs.analchem.5c02035","article-title":"The Raman map of the human cell","volume":"97","author":"Nowakowska","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bbalip.2026.159756_bb0065","article-title":"Spectrolipidomics of glial cell lines: a deuterated probe for semiquantitative monitoring of cannabidiol-induced cholesterol modulation","author":"Chrabaszcz","year":"2026","journal-title":"BioRxiv"},{"key":"10.1016\/j.bbalip.2026.159756_bb0070","article-title":"Lipid droplets in prostate cancer cells and effect of irradiation studied by Raman microspectroscopy","volume":"1865","author":"Roman","year":"2020","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbalip.2026.159756_bb0075","doi-asserted-by":"crossref","DOI":"10.1021\/acssensors.4c01455","article-title":"Sensing biomolecules associated with cells\u2019 radiosusceptibility by advanced micro- and nanospectroscopy techniques","author":"Chrab\u0105szcz","year":"2024","journal-title":"ACS Sens."},{"key":"10.1016\/j.bbalip.2026.159756_bb0080","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.ceb.2008.05.009","article-title":"Cell biology of lipid droplets","volume":"20","author":"Thiele","year":"2008","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.bbalip.2026.159756_bb0085","doi-asserted-by":"crossref","DOI":"10.1021\/acs.jpcb.5c05981","article-title":"Spectroscopic active probes for investigation of lipid transformation in cells and membranes","author":"Chrab\u0105szcz","year":"2026","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bbalip.2026.159756_bb0090","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1002\/jrs.4607","article-title":"Raman spectroscopy of lipids: a review","volume":"46","author":"Czamara","year":"2015","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.bbalip.2026.159756_bb0095","article-title":"Cell lipid droplet heterogeneity and altered biophysical properties induced by cell stress and metabolic imbalance","volume":"1868","author":"Ventura","year":"2023","journal-title":"Biochim. Biophys. Acta Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbalip.2026.159756_bb0100","doi-asserted-by":"crossref","first-page":"1694","DOI":"10.1039\/C2MB05485J","article-title":"The lipid composition of isolated cytoplasmic lipid droplets from a human cancer cell line, BE(2)M17","volume":"8","author":"Pan","year":"2012","journal-title":"Mol. BioSyst."},{"key":"10.1016\/j.bbalip.2026.159756_bb0105","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1155\/2006\/738186","article-title":"Biomedical applications of Raman and infrared spectroscopy to diagnose tissues","volume":"20","author":"Krafft","year":"2006","journal-title":"J. Spectrosc."},{"key":"10.1016\/j.bbalip.2026.159756_bb0110","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1021\/acschemneuro.2c00040","article-title":"Differential interaction of cannabidiol with biomembranes dependent on cholesterol concentration","volume":"13","author":"Perez","year":"2022","journal-title":"ACS Chem. Neurosci."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198126000429?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1388198126000429?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T06:32:51Z","timestamp":1784183571000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1388198126000429"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1388198126000429"],"URL":"https:\/\/doi.org\/10.1016\/j.bbalip.2026.159756","relation":{},"ISSN":["1388-1981"],"issn-type":[{"value":"1388-1981","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lipid droplet isolation as a novel platform for spectroscopic investigation of cargo modifications","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbalip.2026.159756","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"159756"}}