{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T16:59:25Z","timestamp":1761843565884},"reference-count":59,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T00:00:00Z","timestamp":1164931200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":2456,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2006,12]]},"DOI":"10.1016\/j.bbamcr.2006.08.018","type":"journal-article","created":{"date-parts":[[2006,8,27]],"date-time":"2006-08-27T11:06:41Z","timestamp":1156676801000},"page":"1785-1793","source":"Crossref","is-referenced-by-count":42,"title":["Generalised and conditional inactivation of Pex genes in mice"],"prefix":"10.1016","volume":"1763","author":[{"given":"Myriam","family":"Baes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul P.","family":"Van Veldhoven","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2006.08.018_bib1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1146\/annurev.biochem.74.082803.133329","article-title":"Biochemistry of mammalian peroxisomes revisited","volume":"75","author":"Wanders","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib2","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1038\/ng0997-49","article-title":"A mouse model for Zellweger syndrome","volume":"17","author":"Baes","year":"1997","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib3","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1083\/jcb.139.5.1293","article-title":"Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder","volume":"139","author":"Faust","year":"1997","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib4","doi-asserted-by":"crossref","first-page":"5947","DOI":"10.1128\/MCB.23.16.5947-5957.2003","article-title":"Pex13 inactivation in the mouse disrupts peroxisome biogenesis and leads to a Zellweger syndrome phenotype","volume":"23","author":"Maxwell","year":"2003","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib5","series-title":"The Metabolic and Molecular Bases of Inherited Disease","first-page":"3181","article-title":"The peroxisome biogenesis disorders","author":"Gould","year":"2001"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib6","doi-asserted-by":"crossref","first-page":"394","DOI":"10.1002\/cne.10699","article-title":"Abnormal cerebellar histogenesis in Pex2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency","volume":"461","author":"Faust","year":"2003","journal-title":"J. Comp. Neurol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib7","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1242\/jcs.02776","article-title":"Failure of microtubule-mediated peroxisome division and trafficking in disorders with reduced peroxisome abundance","volume":"119","author":"Nguyen","year":"2006","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1002\/jemt.10326","article-title":"Peroxisomal motility and interaction with microtubules","volume":"61","author":"Schrader","year":"2003","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib9","doi-asserted-by":"crossref","first-page":"1477","DOI":"10.1016\/S0002-9440(10)62534-5","article-title":"Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse)","volume":"159","author":"Baumgart","year":"2001","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1128\/MCB.24.1.1-13.2004","article-title":"Disturbed cholesterol homeostasis in a peroxisome-deficient PEX2 knockout mouse model","volume":"24","author":"Kovacs","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib11","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1126\/science.182.4107.62","article-title":"Peroxisomal and mitochondrial defects in the cerebro-hepato-renal syndrome","volume":"182","author":"Goldfischer","year":"1973","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib12","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1203\/00006450-198306000-00018","article-title":"Biochemical studies in the liver and muscle of patients with Zellweger syndrome","volume":"17","author":".Trijbels","year":"1983","journal-title":"Pediatr. Res."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib13","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/0016-5085(80)90931-2","article-title":"Liver in the cerebro-hepato-renal syndrome: defective bile acid synthesis and abnormal mitochondria","volume":"79","author":"Mathis","year":"1980","journal-title":"Gastroenterology"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib14","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1042\/0264-6021:3530673","article-title":"Prenatal and postnatal development of peroxisomal lipid-metabolizing pathways in the mouse","volume":"353","author":"Huyghe","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib15","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.1002\/rcm.1520","article-title":"Mass spectrometric analysis of ceramide perturbations in brain and fibroblasts of mice and human patients with peroxisomal disorders","volume":"18","author":"Pettus","year":"2004","journal-title":"Rapid Commun. Mass. Spectrom."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib16","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/labinvest.3780005","article-title":"Docosahexaenoic acid deficit is not a major pathogenic factor in peroxisome-deficient mice","volume":"80","author":"Janssen","year":"2000","journal-title":"Lab. Invest."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib17","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1016\/S1388-1981(01)00108-1","article-title":"Isoprenoid biosynthesis is not compromised in a Zellweger syndrome mouse model","volume":"1532","author":"Vanhorebeek","year":"2001","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib18","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/S0022-2275(20)30191-7","article-title":"Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis","volume":"43","author":"Hogenboom","year":"2002","journal-title":"J. Lipid Res."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib19","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/BF00689761","article-title":"The mechanism of arrest of neuronal migration in the Zellweger malformation: an hypothesis based upon cytoarchitectonic analysis","volume":"41","author":"Evrard","year":"1978","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/BF00686900","article-title":"Cerebro-hepato-renal syndrome of Zellweger: an inherited disorder of neuronal migration","volume":"20","author":"Volpe","year":"1972","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib21","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1111\/j.1750-3639.1998.tb00139.x","article-title":"Peroxisomal disorders: genotype, phenotype, major neuropathologic lesions, and pathogenesis","volume":"8","author":"Powers","year":"1998","journal-title":"Brain Pathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib22","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1093\/jnen\/61.4.368","article-title":"The neuronal migration defect in mice with Zellweger syndrome (Pex5 knockout) is not caused by the inactivity of peroxisomal b-oxidation","volume":"61","author":"Baes","year":"2002","journal-title":"J. Neuropathol. Exp. Neurol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib23","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1002\/ana.20702","article-title":"The clinical and biochemical spectrum of D-bifunctional protein deficiency","volume":"59","author":"Ferdinandusse","year":"2006","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib24","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1523\/JNEUROSCI.18-01-00307.1998","article-title":"Platelet-activating factor receptor stimulation disrupts neuronal migration in vitro","volume":"18","author":"Bix","year":"1998","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib25","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1002\/1531-8249(200009)48:3<336::AID-ANA8>3.0.CO;2-Q","article-title":"Neuronal migration disorder in Zellweger mice is secondary to glutamate receptor dysfunction","volume":"48","author":"Gressens","year":"2000","journal-title":"Ann. Neurol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib26","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1093\/hmg\/ddg191","article-title":"Inactivation of ether lipid biosynthesis causes male infertility, defects in eye development and optic nerve hypoplasia in mice","volume":"12","author":"Rodemer","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib27","doi-asserted-by":"crossref","first-page":"9732","DOI":"10.1523\/JNEUROSCI.23-30-09732.2003","article-title":"Neuronal migration depends on intact peroxisomal function in brain and in extraneuronal tissues","volume":"23","author":"Janssen","year":"2003","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib28","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1007\/s10545-005-7059-y","article-title":"Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain","volume":"28","author":"Faust","year":"2005","journal-title":"J. Inherit. Metab. Dis."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib29","doi-asserted-by":"crossref","first-page":"2255","DOI":"10.1093\/hmg\/ddg236","article-title":"Impaired neuronal migration and endochondral ossification in PEX7 knockout mice: a model for rhizomelic chondrodysplasia punctata","volume":"12","author":"Brites","year":"2003","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib30","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1023\/A:1023957110171","article-title":"Rhizomelic chondrodysplasia punctata, a peroxisomal biogenesis disorder caused by defects in Pex7p, a peroxisomal protein import receptor: a minireview","volume":"24","author":"Purdue","year":"1999","journal-title":"Neurochem. Res."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib31","doi-asserted-by":"crossref","first-page":"5169","DOI":"10.1111\/j.1742-4658.2005.04939.x","article-title":"Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation","volume":"272","author":"Thoms","year":"2005","journal-title":"FEBS J."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib32","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1083\/jcb.200112028","article-title":"PEX11 promotes peroxisome division independently of peroxisome metabolism","volume":"156","author":"Li","year":"2002","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib33","doi-asserted-by":"crossref","first-page":"29607","DOI":"10.1074\/jbc.273.45.29607","article-title":"Expression of PEX11\u03b2 mediates peroxisome proliferation in the absence of extracellular stimuli","volume":"273","author":"Schrader","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib34","doi-asserted-by":"crossref","first-page":"17012","DOI":"10.1074\/jbc.M212031200","article-title":"The dynamin-like GTPase DLP1 is essential for peroxisome division and is recruited to peroxisomes in part by PEX11","volume":"278","author":"Li","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib35","doi-asserted-by":"crossref","first-page":"8226","DOI":"10.1128\/MCB.22.23.8226-8240.2002","article-title":"PEX11\u03b1 is required for peroxisome proliferation in response to 4-phenylbutyrate but is dispensable for peroxisome proliferator-activated receptor alpha-mediated peroxisome proliferation","volume":"22","author":"Li","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib36","doi-asserted-by":"crossref","first-page":"4358","DOI":"10.1128\/MCB.22.12.4358-4365.2002","article-title":"PEX11\u03b2 deficiency is lethal and impairs neuronal migration but does not abrogate peroxisome function","volume":"22","author":"Li","year":"2002","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib37","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1146\/annurev.cellbio.20.082503.103047","article-title":"Cortical neuronal migration mutants suggest separate but intersecting pathways","volume":"20","author":"Bielas","year":"2004","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib38","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1097\/01.wco.0000218228.73678.e1","article-title":"Pathogenesis of migration disorders","volume":"19","author":"Gressens","year":"2006","journal-title":"Curr. Opin. Neurol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib39","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1002\/gene.10068","article-title":"Conditional alleles in mice: practical considerations for tissue-specific knockouts","volume":"32","author":"Kwan","year":"2002","journal-title":"Genesis"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib40","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/gene.10047","article-title":"Generation of Pex5-IoxP mice allowing the conditional elimination of peroxisomes","volume":"32","author":"Baes","year":"2002","journal-title":"Genesis"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib41","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/gene.10044","article-title":"Conditional inactivation of the peroxisome biogenesis Pex13 gene by Cre-IoxP excision","volume":"32","author":"Bjorkman","year":"2002","journal-title":"Genesis"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib42","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1074\/jbc.274.1.305","article-title":"Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic \u03b2 cell-specific gene knock-outs using Cre recombinase","volume":"274","author":"Postic","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib43","doi-asserted-by":"crossref","first-page":"868","DOI":"10.1002\/hep.20628","article-title":"Absence of peroxisomes in hepatocytes causes mitochondrial and ER abnormalities","volume":"41","author":"Dirkx","year":"2005","journal-title":"Hepatology"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib44","first-page":"90","article-title":"The testis in adreno-leukodystrophy","volume":"102","author":"Powers","year":"1981","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib45","series-title":"The Metabolic and Molecular Bases of Inherited Disease","first-page":"3257","article-title":"X-linked adrenoleukodystrophy","author":"Moser","year":"2001"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib46","doi-asserted-by":"crossref","first-page":"2474","DOI":"10.1093\/humrep\/13.9.2474","article-title":"Rapid decline of fertility in a case of adrenoleukodystrophy","volume":"13","author":"Aversa","year":"1998","journal-title":"Hum. Reprod."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib47","doi-asserted-by":"crossref","first-page":"24698","DOI":"10.1074\/jbc.271.40.24698","article-title":"Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene","volume":"271","author":"Fan","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib48","doi-asserted-by":"crossref","first-page":"2228","DOI":"10.1210\/en.2005-1571","article-title":"Peroxisomal multifunctional protein 2 is essential for lipid homeostasis in Sertoli cells and for male fertility in mice","volume":"147","author":"Huyghe","year":"2006","journal-title":"Endocrinology"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib49","first-page":"1","article-title":"Peroxisomes are present in murine spermatogonia and disappear during the course of spermatogenesis","volume":"30","author":"L\u00fcers","year":"2005","journal-title":"Histochem. Cell Biol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib50","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1002\/gene.10100","article-title":"Sertoli and granulosa cell-specific Cre recombinase activity in transgenic mice","volume":"33","author":"Lecureuil","year":"2002","journal-title":"Genesis"},{"key":"10.1016\/j.bbamcr.2006.08.018_bib51","doi-asserted-by":"crossref","first-page":"15775","DOI":"10.1074\/jbc.274.22.15775","article-title":"Absence of spontaneous peroxisome proliferation in enoyl-CoA hydratase\/L-3-hydroxyacyl-CoA dehydrogenase-deficient mouse liver","volume":"274","author":"Qi","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib52","doi-asserted-by":"crossref","first-page":"16329","DOI":"10.1074\/jbc.M001994200","article-title":"Inactivation of the peroxisomal multifunctional protein-2 in mice impedes the degradation of not only 2-methyl branched fatty acids and bile acid intermediates but also of very long chain fatty acids","volume":"275","author":"Baes","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib53","doi-asserted-by":"crossref","first-page":"1321","DOI":"10.2353\/ajpath.2006.041220","article-title":"Peroxisomal multifunctional protein-2 deficiency causes motor deficits and glial lesions in the adult CNS","volume":"168","author":"Huyghe","year":"2006","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib54","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.1101\/gad.12.8.1189","article-title":"Defective peroxisomal catabolism of branched fatty acyl coenzyme A in mice lacking the sterol carrier protein-2\/sterol carrier protein-x gene function","volume":"12","author":"Seedorf","year":"1998","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib55","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1093\/hmg\/ddh107","article-title":"A mouse model for a-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietay methyl-branched lipids","volume":"13","author":"Savolainen","year":"2004","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib56","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1002\/(SICI)1097-4547(19971201)50:5<829::AID-JNR19>3.0.CO;2-W","article-title":"Targeted inactivation of the X-linked adrenoleukodystrophy gene in mice","volume":"50","author":"Forss-Petter","year":"1997","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib57","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1006\/bbrc.1997.6340","article-title":"Adrenoleukodystrophy protein-deficient mice represent abnormality of very long chain fatty acid metabolism","volume":"232","author":"Kobayashi","year":"1997","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib58","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1093\/hmg\/11.5.499","article-title":"Late onset neurological phenotype of the X-ALD gene inactivation in mice: a mouse model for adrenomyeloneuropathy","volume":"11","author":"Pujol","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2006.08.018_bib59","doi-asserted-by":"crossref","first-page":"3565","DOI":"10.1093\/hmg\/ddi384","article-title":"Inactivation of the peroxisomal ABCD2 transporter in the mouse leads to late-onset ataxia involving mitochondria, Golgi and endoplasmic reticulum damage","volume":"14","author":"Ferrer","year":"2005","journal-title":"Hum. Mol. Genet."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488906002321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488906002321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,7,31]],"date-time":"2021-07-31T21:37:38Z","timestamp":1627767458000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488906002321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12]]},"references-count":59,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2006,12]]}},"alternative-id":["S0167488906002321"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2006.08.018","relation":{},"ISSN":["0167-4889"],"issn-type":[{"type":"print","value":"0167-4889"}],"subject":[],"published":{"date-parts":[[2006,12]]}}}