{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T22:45:05Z","timestamp":1791326705520,"version":"4.3.1"},"reference-count":36,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2013,8,22]],"date-time":"2013-08-22T00:00:00Z","timestamp":1377129600000},"content-version":"vor","delay-in-days":2394,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.bbamcr.2006.09.031","type":"journal-article","created":{"date-parts":[[2006,10,4]],"date-time":"2006-10-04T11:50:52Z","timestamp":1159962652000},"page":"192-200","source":"Crossref","is-referenced-by-count":40,"title":["CFTR surface expression and chloride currents are decreased by inhibitors of N-WASP and actin polymerization"],"prefix":"10.1016","volume":"1773","author":[{"given":"Radhika","family":"Ganeshan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Nowotarski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anke","family":"Di","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deborah J.","family":"Nelson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin L.","family":"Kirk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2006.09.031_bib1","doi-asserted-by":"crossref","first-page":"5192","DOI":"10.1073\/pnas.91.11.5192","article-title":"Rapid endocytosis of the cystic fibrosis transmembrane conductance regulator chloride channel","volume":"91","author":"Prince","year":"1994","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"Pt 2","key":"10.1016\/j.bbamcr.2006.09.031_bib2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1042\/bj3280353","article-title":"Constitutive internalization of cystic fibrosis transmembrane conductance regulator occurs via clathrin-dependent endocytosis and is regulated by protein phosphorylation","volume":"328","author":"Lukacs","year":"1997","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib3","doi-asserted-by":"crossref","first-page":"8296","DOI":"10.1016\/S0021-9258(17)37192-2","article-title":"Biochemical and biophysical identification of cystic fibrosis transmembrane conductance regulator chloride channels as components of endocytic clathrin-coated vesicles","volume":"269","author":"Bradbury","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib4","doi-asserted-by":"crossref","first-page":"46251","DOI":"10.1074\/jbc.M104545200","article-title":"Mu 2 binding directs the cystic fibrosis transmembrane conductance regulator to the clathrin-mediated endocytic pathway","volume":"276","author":"Weixel","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib5","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/0264-6021:3540561","article-title":"Multiple endocytic signals in the C-terminal tail of the cystic fibrosis transmembrane conductance regulator","volume":"354","author":"Hu","year":"2001","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib6","doi-asserted-by":"crossref","first-page":"C1009","DOI":"10.1152\/ajpcell.00140.2003","article-title":"Rme-1 regulates the recycling of the cystic fibrosis transmembrane conductance regulator","volume":"285","author":"Picciano","year":"2003","journal-title":"Am. J. Physiol.: Cell Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib7","doi-asserted-by":"crossref","first-page":"C375","DOI":"10.1152\/ajpcell.2000.279.2.C375","article-title":"Forskolin-induced apical membrane insertion of virally expressed, epitope-tagged CFTR in polarized MDCK cells","volume":"279","author":"Howard","year":"2000","journal-title":"Am. J. Physiol.: Cell Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib8","doi-asserted-by":"crossref","first-page":"F111","DOI":"10.1083\/jcb.150.5.F111","article-title":"Molecular links between endocytosis and the actin cytoskeleton","volume":"150","author":"Qualmann","year":"2000","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib9","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1078\/0171-9335-00356","article-title":"Neural Wiskott Aldrich Syndrome Protein (N-WASP) and the Arp2\/3 complex are recruited to sites of clathrin-mediated endocytosis in cultured fibroblasts","volume":"83","author":"Merrifield","year":"2004","journal-title":"Eur. J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib10","doi-asserted-by":"crossref","first-page":"20332","DOI":"10.1074\/jbc.272.33.20332","article-title":"The actin cytoskeleton is required for receptor-mediated endocytosis in mammalian cells","volume":"272","author":"Lamaze","year":"1997","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib11","doi-asserted-by":"crossref","first-page":"C97","DOI":"10.1152\/ajpcell.1998.274.1.C97","article-title":"State of actin in gastric parietal cells","volume":"274","author":"Forte","year":"1998","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib12","doi-asserted-by":"crossref","first-page":"6382","DOI":"10.1016\/S0021-9258(19)39337-8","article-title":"Selective modulation of the endocytic uptake of ricin and fluid phase markers without alteration in transferrin endocytosis","volume":"265","author":"Sandvig","year":"1990","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib13","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1034\/j.1600-0854.2000.010208.x","article-title":"Actin assembly plays a variable, but not obligatory role in receptor-mediated endocytosis in mammalian cells","volume":"1","author":"Fujimoto","year":"2000","journal-title":"Traffic"},{"key":"10.1016\/j.bbamcr.2006.09.031_bib14","doi-asserted-by":"crossref","first-page":"38025","DOI":"10.1074\/jbc.M403141200","article-title":"Myosin VI regulates endocytosis of the cystic fibrosis transmembrane conductance regulator","volume":"279","author":"Swiatecka-Urban","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib15","doi-asserted-by":"crossref","first-page":"C1552","DOI":"10.1152\/ajpcell.1995.268.6.C1552","article-title":"cAMP-independent regulation of CFTR by the actin cytoskeleton","volume":"268","author":"Prat","year":"1995","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib16","doi-asserted-by":"crossref","first-page":"C1160","DOI":"10.1152\/ajpcell.1999.277.6.C1160","article-title":"Actin filament organization is required for proper cAMP-dependent activation of CFTR","volume":"277","author":"Prat","year":"1999","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib17","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1038\/nsmb796","article-title":"Chemical inhibition of N-WASP by stabilization of a native autoinhibited conformation","volume":"11","author":"Peterson","year":"2004","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib18","doi-asserted-by":"crossref","first-page":"2636","DOI":"10.1091\/mbc.E05-01-0043","article-title":"Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex","volume":"16","author":"Ivanov","year":"2005","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbamcr.2006.09.031_bib19","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0076-6879(06)06021-6","article-title":"Biochemical properties and inhibitors of (N-)WASP","volume":"406","author":"Leung","year":"2006","journal-title":"Methods Enzymol"},{"key":"10.1016\/j.bbamcr.2006.09.031_bib20","doi-asserted-by":"crossref","first-page":"3103","DOI":"10.1242\/jcs.02444","article-title":"N-WASP deficiency impairs EGF internalization and actin assembly at clathrin-coated pits","volume":"118","author":"Benesch","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib21","doi-asserted-by":"crossref","first-page":"49331","DOI":"10.1074\/jbc.M109657200","article-title":"Insulin stimulates actin comet tails on intracellular GLUT4-containing compartments in differentiated 3T3L1 adipocytes","volume":"276","author":"Kanzaki","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib22","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1074\/jbc.M108280200","article-title":"A phosphatidylinositol 3-kinase-independent insulin signaling pathway to N-WASP\/Arp2\/3\/F-actin required for GLUT4 glucose transporter recycling","volume":"277","author":"Jiang","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib23","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1242\/jcs.00890","article-title":"Trafficking of beta2-adrenergic receptors: insulin and beta-agonists regulate internalization by distinct cytoskeletal pathways","volume":"117","author":"Shumay","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib24","doi-asserted-by":"crossref","first-page":"29102","DOI":"10.1074\/jbc.274.41.29102","article-title":"Association of cystic fibrosis transmembrane conductance regulator and protein phosphatase 2C","volume":"274","author":"Zhu","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib25","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1038\/36882","article-title":"Regulation of CFTR chloride channels by syntaxin and Munc18 isoforms","volume":"390","author":"Naren","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2006.09.031_bib26","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1007\/BF00656997","article-title":"Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches","volume":"391","author":"Hamill","year":"1981","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib27","first-page":"323","article-title":"Analysis of CFTR endocytosis by cell surface biotinylation","volume":"70","author":"Weixel","year":"2002","journal-title":"Methods Mol. Med."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib28","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1085\/jgp.200409115","article-title":"Reversible silencing of CFTR chloride channels by glutathionylation","volume":"125","author":"Wang","year":"2005","journal-title":"J. Gen. Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib29","doi-asserted-by":"crossref","first-page":"42936","DOI":"10.1074\/jbc.M406493200","article-title":"ExoS Rho GTPase-activating protein activity stimulates reorganization of the actin cytoskeleton through Rho GTPase guanine nucleotide disassociation inhibitor","volume":"279","author":"Sun","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib30","doi-asserted-by":"crossref","first-page":"C862","DOI":"10.1152\/ajpcell.00108.2005","article-title":"Pseudomonas aeruginosa inhibits endocytic recycling of CFTR in polarized human airway epithelial cells","volume":"290","author":"Swiatecka-Urban","year":"2006","journal-title":"Am. J. Physiol.: Cell Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib31","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1007\/s00249-001-0188-9","article-title":"Evidence for direct interaction between actin and the cystic fibrosis transmembrane conductance regulator","volume":"30","author":"Chasan","year":"2002","journal-title":"Eur. Biophys. J."},{"issue":"Pt 3","key":"10.1016\/j.bbamcr.2006.09.031_bib32","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1113\/jphysiol.1995.sp021088","article-title":"The actin filament disrupter cytochalasin D activates the recombinant cystic fibrosis transmembrane conductance regulator Cl\u2212 channel in mouse 3T3 fibroblasts","volume":"489","author":"Fischer","year":"1995","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib33","doi-asserted-by":"crossref","first-page":"19797","DOI":"10.1074\/jbc.273.31.19797","article-title":"An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton","volume":"273","author":"Short","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib34","doi-asserted-by":"crossref","first-page":"29539","DOI":"10.1074\/jbc.M004961200","article-title":"E3KARP mediates the association of ezrin and protein kinase A with the cystic fibrosis transmembrane conductance regulator in airway cells","volume":"275","author":"Sun","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib35","doi-asserted-by":"crossref","first-page":"5494","DOI":"10.1074\/jbc.M312445200","article-title":"Increased diffusional mobility of CFTR at the plasma membrane after deletion of its C-terminal PDZ binding motif","volume":"279","author":"Haggie","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2006.09.031_bib36","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.1073\/pnas.98.3.1261","article-title":"Contribution of cytoskeleton to the internalization of AMPA receptors","volume":"98","author":"Zhou","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488906003132?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488906003132?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,1]],"date-time":"2021-08-01T20:05:49Z","timestamp":1627848349000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488906003132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":36,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0167488906003132"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2006.09.031","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}