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Physiol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0350","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1126\/science.2017683","article-title":"Calcium as a coagonist of inositol 1, 4, 5-trisphosphate-induced calcium release","volume":"252","author":"Finch","year":"1991","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0355","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1038\/351751a0","article-title":"Bell-shaped calcium-response curves of Ins(1, 4, 5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum","volume":"351","author":"Bezprozvanny","year":"1991","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0360","doi-asserted-by":"crossref","first-page":"18776","DOI":"10.1016\/S0021-9258(19)37028-0","article-title":"Isolation, characterization, and localization of the inositol 1, 4, 5-trisphosphate receptor protein in Xenopus laevis oocytes","volume":"267","author":"Parys","year":"1992","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0365","doi-asserted-by":"crossref","first-page":"52881","DOI":"10.1074\/jbc.M309743200","article-title":"Three-dimensional rearrangements within inositol 1, 4, 5-trisphosphate receptor by calcium","volume":"278","author":"Hamada","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0370","doi-asserted-by":"crossref","first-page":"25085","DOI":"10.1074\/jbc.M110.123208","article-title":"Calcium dependent conformational changes in inositol trisphosphate receptors","volume":"285","author":"Anyatonwu","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0375","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1146\/annurev.biochem.73.071403.161303","article-title":"Inositol 1, 4, 5-trisphosphate receptors as signal integrators","volume":"73","author":"Patterson","year":"2004","journal-title":"Annu. Rev. 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Res."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0410","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1242\/jcs.00354","article-title":"Microtubule-dependent redistribution of the type-1 inositol 1, 4, 5-trisphosphate receptor in A7r5 smooth muscle cells","volume":"116","author":"Vermassen","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0415","doi-asserted-by":"crossref","first-page":"2791","DOI":"10.1242\/jcs.00482","article-title":"The type 3 inositol 1, 4, 5-trisphosphate receptor is concentrated at the tight junction level in polarized MDCK cells","volume":"116","author":"Colosetti","year":"2003","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0420","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1042\/BJ20081016","article-title":"At the crossroads of homoeostasis and disease: roles of the PACS proteins in membrane traffic and apoptosis","volume":"421","author":"Youker","year":"2009","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0425","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1038\/sj.emboj.7600559","article-title":"PACS-2 controls endoplasmic reticulum\u2013mitochondria communication and Bid-mediated apoptosis","volume":"24","author":"Simmen","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0430","doi-asserted-by":"crossref","first-page":"1115","DOI":"10.1083\/jcb.200212059","article-title":"Caspase cleavage product of BAP31 induces mitochondrial fission through endoplasmic reticulum calcium signals, enhancing cytochrome c release to the cytosol","volume":"160","author":"Breckenridge","year":"2003","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0435","doi-asserted-by":"crossref","first-page":"2777","DOI":"10.1091\/mbc.E07-10-0995","article-title":"The subcellular distribution of calnexin is mediated by PACS-2","volume":"19","author":"Myhill","year":"2008","journal-title":"Mol. Biol. 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Ther."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0470","doi-asserted-by":"crossref","first-page":"5029","DOI":"10.1158\/0008-5472.CAN-03-2329","article-title":"Sigma receptors and cancer: possible involvement of ion channels","volume":"64","author":"Aydar","year":"2004","journal-title":"Cancer Res."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0475","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.cell.2007.08.036","article-title":"Sigma-1 receptor chaperones at the ER\u2013mitochondrion interface regulate Ca2+ signaling and cell survival","volume":"131","author":"Hayashi","year":"2007","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0480","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/S0022-3565(24)39299-7","article-title":"Ca2+ signaling via sigma1-receptors: novel regulatory mechanism affecting intracellular Ca2+ concentration","volume":"293","author":"Hayashi","year":"2000","journal-title":"J. Pharmacol. Exp. Ther."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0485","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1073\/pnas.98.2.491","article-title":"Regulating ankyrin dynamics: roles of sigma-1 receptors","volume":"98","author":"Hayashi","year":"2001","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0490","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1379\/1466-1268(2002)007<0309:AHFCMM>2.0.CO;2","article-title":"An Hsp70 family chaperone, mortalin\/mthsp70\/PBP74\/Grp75: what, when, and where?","volume":"7","author":"Wadhwa","year":"2002","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0495","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.exger.2006.10.020","article-title":"Three faces of mortalin: a housekeeper, guardian and killer","volume":"42","author":"Kaul","year":"2007","journal-title":"Exp. Gerontol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0500","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1083\/jcb.200608073","article-title":"Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels","volume":"175","author":"Szabadkai","year":"2006","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0505","doi-asserted-by":"crossref","first-page":"34433","DOI":"10.1074\/jbc.274.48.34433","article-title":"Inositol 1, 4, 5-trisphosphate receptor type 1 is a substrate for caspase-3 and is cleaved during apoptosis in a caspase-3-dependent manner","volume":"274","author":"Hirota","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0510","doi-asserted-by":"crossref","first-page":"43227","DOI":"10.1074\/jbc.M403872200","article-title":"Caspase-3-induced truncation of type 1 inositol trisphosphate receptor accelerates apoptotic cell death and induces inositol trisphosphate-independent calcium release during apoptosis","volume":"279","author":"Assefa","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0515","doi-asserted-by":"crossref","first-page":"29158","DOI":"10.1074\/jbc.M109.041509","article-title":"G-protein-coupled receptor kinase-interacting proteins inhibit apoptosis by inositol 1, 4, 5-triphosphate receptor-mediated Ca2+ signal regulation","volume":"284","author":"Zhang","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0520","doi-asserted-by":"crossref","first-page":"3731","DOI":"10.1074\/jbc.M509262200","article-title":"Akt kinase phosphorylation of inositol 1, 4, 5-trisphosphate receptors","volume":"281","author":"Khan","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0525","doi-asserted-by":"crossref","first-page":"2427","DOI":"10.1073\/pnas.0711324105","article-title":"Phosphorylation of inositol 1, 4, 5-trisphosphate receptors by protein kinase B\/Akt inhibits Ca2+ release and apoptosis","volume":"105","author":"Szado","year":"2008","journal-title":"Proc. Natl. Acad. Sci. 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Chem."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0550","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1038\/ncb1063","article-title":"Cytochrome c binds to inositol (1, 4, 5) trisphosphate receptors, amplifying calcium-dependent apoptosis","volume":"5","author":"Boehning","year":"2003","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0555","doi-asserted-by":"crossref","first-page":"6511","DOI":"10.1016\/S0021-9258(18)53280-4","article-title":"Apoptosis induced by withdrawal of interleukin-3 (IL-3) from an IL-3-dependent hematopoietic cell line is associated with repartitioning of intracellular calcium and is blocked by enforced Bcl-2 oncoprotein production","volume":"268","author":"Baffy","year":"1993","journal-title":"J. Biol. 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Virol."},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0650","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1016\/S0143416002001872","article-title":"Old players in a new role: mitochondria-associated membranes, VDAC, and ryanodine receptors as contributors to calcium signal propagation from endoplasmic reticulum to the mitochondria","volume":"32","author":"Hajn\u00f3czky","year":"2002","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0655","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1054\/ceca.2000.0191","article-title":"Sorting of calcium signals at the junctions of endoplasmic reticulum and mitochondria","volume":"29","author":"Csord\u00e1s","year":"2001","journal-title":"Cell Calcium"},{"key":"10.1016\/j.bbamcr.2010.11.023_bb0660","doi-asserted-by":"crossref","first-page":"F1303","DOI":"10.1152\/ajprenal.90343.2008","article-title":"Uncoupling of ER\u2013mitochondrial calcium communication by transforming growth factor-\u03b2","volume":"295","author":"Pacher","year":"2008","journal-title":"Am. 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