{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:22:25Z","timestamp":1791217345109,"version":"4.1.0"},"reference-count":63,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Natural Sciences and Engineering Research Council of Canada (NSERC)"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.bbamcr.2013.04.014","type":"journal-article","created":{"date-parts":[[2013,5,1]],"date-time":"2013-05-01T21:31:56Z","timestamp":1367443916000},"page":"3426-3435","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":49,"title":["Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts"],"prefix":"10.1016","volume":"1833","author":[{"given":"Aaron D.","family":"Dam","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Quadrilatero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2013.04.014_bb0005","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/S0002-9343(99)00259-4","article-title":"Apoptosis: definition, mechanisms, and relevance to disease","volume":"107","author":"Saikumar","year":"1999","journal-title":"Am. J. Med."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0010","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1038\/nrd726","article-title":"Apoptosis-based therapies","volume":"1","author":"Reed","year":"2002","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0015","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/cdd.2008.150","article-title":"Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009","volume":"16","author":"Kroemer","year":"2009","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0020","doi-asserted-by":"crossref","first-page":"608","DOI":"10.1139\/h11-064","article-title":"Skeletal muscle apoptotic response to physical activity: potential mechanisms for protection","volume":"36","author":"Quadrilatero","year":"2011","journal-title":"Appl. Physiol. Nutr. Metab."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0025","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1242\/jcs.01610","article-title":"Death receptor signaling","volume":"118","author":"Lavrik","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0030","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1152\/physrev.00013.2006","article-title":"Mitochondrial membrane permeabilization in cell death","volume":"87","author":"Kroemer","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0035","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1007\/s10495-009-0341-y","article-title":"Cellular responses to endoplasmic reticulum stress and apoptosis","volume":"14","author":"Rasheva","year":"2009","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0040","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1038\/nrm2952","article-title":"Mitochondria and cell death: outer membrane permeabilization and beyond","volume":"11","author":"Tait","year":"2010","journal-title":"Nat. Rev. Mol. Cell Biol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0045","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0092-8674(00)80434-1","article-title":"Cytochrome c and dATP-dependent formation of Apaf-1\/caspase-9 complex initiates an apoptotic protease cascade","volume":"91","author":"Li","year":"1997","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0050","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0092-8674(00)00008-8","article-title":"Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition","volume":"102","author":"Du","year":"2000","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0055","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1038\/40901","article-title":"X-linked IAP is a direct inhibitor of cell-death proteases","volume":"388","author":"Deveraux","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0060","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/17135","article-title":"Molecular characterization of mitochondrial apoptosis-inducing factor","volume":"397","author":"Susin","year":"1999","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0065","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1096\/fasebj.14.5.729","article-title":"Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis","volume":"14","author":"Daugas","year":"2000","journal-title":"FASEB J."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0070","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0092-8674(00)80611-X","article-title":"Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1","volume":"98","author":"Wu","year":"1999","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0075","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nature00904","article-title":"Transcriptional co-activator PGC-1\u03b1 drives the formation of slow-twitch muscle fibres","volume":"418","author":"Lin","year":"2002","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0080","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1152\/jappl.2001.90.3.1137","article-title":"Invited review: contractile activity-induced mitochondrial biogenesis in skeletal muscle","volume":"90","author":"Hood","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0085","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1096\/fj.03-1291fje","article-title":"Apoptotic adaptations from exercise training in skeletal and cardiac muscles","volume":"18","author":"Siu","year":"2004","journal-title":"FASEB J."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0090","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1089\/ars.2006.8.517","article-title":"Exercise training attenuates age-induced changes in apoptotic signaling in rat skeletal muscle","volume":"8","author":"Song","year":"2006","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0095","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1152\/japplphysiol.00290.2012","article-title":"Decreased DNA fragmentation and apoptotic signaling in soleus muscle of hypertensive rats following 6weeks of treadmill training","volume":"113","author":"McMillan","year":"2012","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0100","doi-asserted-by":"crossref","first-page":"4135","DOI":"10.1073\/pnas.1019581108","article-title":"Endurance exercise rescues progeroid aging and induces systemic mitochondrial rejuvenation in mtDNA mutator mice","volume":"108","author":"Safdar","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0105","doi-asserted-by":"crossref","first-page":"C841","DOI":"10.1152\/ajpcell.1991.260.4.C841","article-title":"Mitochondrial adaptations in denervated muscle: relationship to muscle performance","volume":"260","author":"Wicks","year":"1991","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0110","doi-asserted-by":"crossref","first-page":"1730","DOI":"10.1152\/japplphysiol.91451.2008","article-title":"Relationship between SIRT1 expression and mitochondrial proteins during conditions of chronic muscle use and disuse","volume":"107","author":"Chabi","year":"2009","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0115","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1113\/jphysiol.2004.081083","article-title":"Mitochondria-associated apoptotic signalling in denervated rat skeletal muscle","volume":"565","author":"Siu","year":"2005","journal-title":"J. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0120","doi-asserted-by":"crossref","first-page":"R1288","DOI":"10.1152\/ajpregu.00576.2004","article-title":"Age-related differences in apoptosis with disuse atrophy in soleus muscle","volume":"288","author":"Leeuwenburgh","year":"2005","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0125","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1371\/journal.pmed.0040076","article-title":"Calorie restriction increases muscle mitochondrial biogenesis in healthy humans","volume":"4","author":"Civitarese","year":"2007","journal-title":"PLoS Med."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0315","volume":"6","author":"Cerqueira","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0320","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1096\/fj.04-2870fje","article-title":"Muscle fiber-specific apoptosis and TNF-\u03b1 signaling in sarcopenia are attenuated by life-long calorie restriction","author":"Phillips","year":"2005","journal-title":"FASEB J."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0140","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.freeradbiomed.2003.10.003","article-title":"Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12","volume":"36","author":"Dirks","year":"2004","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0145","doi-asserted-by":"crossref","first-page":"15364","DOI":"10.1073\/pnas.93.26.15364","article-title":"Effect of age on in vivo rates of mitochondrial protein synthesis in human skeletal muscle","volume":"93","author":"Rooyackers","year":"1996","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0150","doi-asserted-by":"crossref","first-page":"5618","DOI":"10.1073\/pnas.0501559102","article-title":"Decline in skeletal muscle mitochondrial function with aging in humans","volume":"102","author":"Short","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0155","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1093\/gerona\/61.3.245","article-title":"Molecular regulation of apoptosis in fast plantaris muscles of aged rats","volume":"61","author":"Pistilli","year":"2006","journal-title":"J. Gerontol. A Biol. Sci. Med. Sci."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0160","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1152\/japplphysiol.00377.2009","article-title":"Central role of nitric oxide synthase in AICAR and caffeine-induced mitochondrial biogenesis in L6 myocytes","volume":"108","author":"McConell","year":"2010","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0165","doi-asserted-by":"crossref","first-page":"16507","DOI":"10.1073\/pnas.0405432101","article-title":"Mitochondrial biogenesis by NO yields functionally active mitochondria in mammals","volume":"101","author":"Nisoli","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0170","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1038\/sj.cdd.4401784","article-title":"Regulation of Ca2+ signalling and Ca2+-mediated cell death by the transcriptional coactivator PGC-1\u03b1","volume":"13","author":"Bianchi","year":"2006","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0175","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1016\/j.lfs.2009.01.014","article-title":"Apoptotic signaling induced by H2O2-mediated oxidative stress in differentiated C2C12 myotubes","volume":"84","author":"Siu","year":"2009","journal-title":"Life Sci."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0180","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1007\/s10495-011-0654-5","article-title":"Elevated skeletal muscle apoptotic signaling following glutathione depletion","volume":"17","author":"Dam","year":"2012","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0185","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s10495-007-0720-1","article-title":"Methods for the assessment of mitochondrial membrane permeabilization in apoptosis","volume":"12","author":"Galluzzi","year":"2007","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0190","doi-asserted-by":"crossref","first-page":"R531","DOI":"10.1152\/ajpregu.00488.2010","article-title":"Differential apoptosis-related protein expression, mitochondrial properties, proteolytic enzyme activity, and DNA fragmentation between skeletal muscles","volume":"300","author":"McMillan","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0195","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1038\/sj.cdd.4401263","article-title":"A new quantitative assay for cytochrome c release in apoptosis cells","volume":"10","author":"Waterhouse","year":"2003","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0200","first-page":"307","article-title":"Assaying cytochrome C translocation during apoptosis","volume":"284","author":"Waterhouse","year":"2004","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0205","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1023\/A:1025546525894","article-title":"Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization","volume":"8","author":"Poncet","year":"2003","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0210","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1046\/j.1432-1327.1999.00725.x","article-title":"Mitochondria and cell death. Mechanistic aspects and methodological issues","volume":"264","author":"Bernardi","year":"1999","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0215","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1152\/jappl.2000.88.6.2219","article-title":"Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle","volume":"88","author":"Winder","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0220","doi-asserted-by":"crossref","first-page":"E1040","DOI":"10.1152\/ajpendo.00242.2002","article-title":"Intermittent increases in cytosolic Ca2+ stimulate mitochondrial biogenesis in muscle cells","volume":"283","author":"Ojuka","year":"2002","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0225","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1007\/s00125-010-1764-2","article-title":"Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals","volume":"53","author":"Phielix","year":"2010","journal-title":"Diabetologia"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0230","doi-asserted-by":"crossref","first-page":"R67","DOI":"10.1152\/ajpregu.00417.2010","article-title":"Nuclear SIRT1 activity, but not protein content, regulates mitochondrial biogenesis in rat and human skeletal muscle","volume":"301","author":"Gurd","year":"2011","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0235","doi-asserted-by":"crossref","first-page":"20405","DOI":"10.1073\/pnas.0911570106","article-title":"Increased muscle PGC-1\u03b1 expression protects from sarcopenia and metabolic disease during aging","volume":"106","author":"Wenz","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0240","doi-asserted-by":"crossref","first-page":"E1341","DOI":"10.1152\/ajpendo.00095.2006","article-title":"Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance","volume":"291","author":"Turpin","year":"2006","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0245","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.biocel.2006.07.009","article-title":"Activation of mitochondrial-driven poptosis in skeletal muscle cells is not mediated by reactive oxygen species production","volume":"39","author":"C\u00e1mara","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0250","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1126\/science.1072221","article-title":"Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor","volume":"297","author":"Yu","year":"2002","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0255","doi-asserted-by":"crossref","first-page":"796","DOI":"10.1007\/s10495-009-0353-7","article-title":"Apoptosis-inducing factor plays a critical role in caspase-independent, pyknotic cell death in hydrogen peroxide-exposed cells","volume":"14","author":"Son","year":"2009","journal-title":"Apoptosis"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0260","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.bbrc.2010.02.163","article-title":"Mitochondrial regulation of cell death: processing of apoptosis-inducing factor (AIF)","volume":"396","author":"Norberg","year":"2010","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0265","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1016\/j.tcb.2006.03.008","article-title":"Apoptosis-inducing factor: vital and lethal","volume":"16","author":"Modjtahedi","year":"2006","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0270","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1016\/j.freeradbiomed.2009.12.020","article-title":"Oxidative modification sensitizes mitochondrial apoptosis-inducing factor to calpain-mediated processing","volume":"48","author":"Norberg","year":"2010","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0275","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1073\/pnas.0510452103","article-title":"Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency","volume":"103","author":"L\u00f3pez-Lluch","year":"2006","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0280","doi-asserted-by":"crossref","first-page":"E429","DOI":"10.1152\/ajpendo.00435.2004","article-title":"Long-term caloric restriction increases UCP3 content but decreases proton leak and reactive oxygen species production in rat skeletal muscle mitochondria","volume":"289","author":"Bevilacqua","year":"2005","journal-title":"Am. J. Physiol. Endocrinol. Metab."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0285","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1006\/abbi.1999.1494","article-title":"Effect of training on H2O2 release by mitochondria from rat skeletal muscle","volume":"372","author":"Venditti","year":"1999","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0290","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/S0891-5849(03)00177-1","article-title":"Effect of voluntary exercise on H2O2 release by subsarcolemmal and intermyofibrillar mitochondria","volume":"35","author":"Servais","year":"2003","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0295","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1749-6632.2012.06738.x","article-title":"Role of PGC-1\u03b1 signaling in skeletal muscle health and disease","volume":"1271","author":"Kang","year":"2012","journal-title":"Ann. N. Y. Acad. Sci."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0300","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.cell.2006.09.024","article-title":"Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators","volume":"127","author":"St-Pierre","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0305","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1007\/s11906-010-0157-8","article-title":"Mitochondrial biogenesis and fragmentation as regulators of muscle protein degradation","volume":"12","author":"Romanello","year":"2010","journal-title":"Curr. Hypertens. Rep."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0310","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.molcel.2004.09.026","article-title":"Drp-1-dependent division of the mitochondrial network blocks intraorganellar Ca2+ waves and protects against Ca2+-mediated apoptosis","volume":"16","author":"Szabadkai","year":"2004","journal-title":"Mol. Cell."},{"key":"10.1016\/j.bbamcr.2013.04.014_bb0325","first-page":"1","article-title":"Mild stress of caffeine increased mtDNA content in skeletal muscle cells: the interplay between Ca2+ transients and nitric oxide","author":"Ding","year":"2012","journal-title":"J. Muscle Res. Cell Motil."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488913001742?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488913001742?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,7,13]],"date-time":"2019-07-13T04:10:47Z","timestamp":1562991047000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488913001742"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":63,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0167488913001742"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2013.04.014","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Induction of mitochondrial biogenesis protects against caspase-dependent and caspase-independent apoptosis in L6 myoblasts","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2013.04.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}