{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T16:47:21Z","timestamp":1790614041300,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2013,12,1]],"date-time":"2013-12-01T00:00:00Z","timestamp":1385856000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2013,12]]},"DOI":"10.1016\/j.bbamcr.2013.09.021","type":"journal-article","created":{"date-parts":[[2013,10,5]],"date-time":"2013-10-05T04:33:01Z","timestamp":1380947581000},"page":"3237-3244","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":21,"title":["DNA loop domain organization as revealed by single-cell gel electrophoresis"],"prefix":"10.1016","volume":"1833","author":[{"given":"Katerina","family":"Afanasieva","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Chopei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marianna","family":"Zazhytska","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Vikhreva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Sivolob","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2013.09.021_bb0005","doi-asserted-by":"crossref","first-page":"a000596","DOI":"10.1101\/cshperspect.a000596","article-title":"Chromatin higher-order structure and dynamics","volume":"2","author":"Woodcock","year":"2010","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0010","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1038\/nrg3454","article-title":"Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data","volume":"14","author":"Dekker","year":"2013","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0015","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1016\/j.molcel.2013.02.011","article-title":"The hierarchy of the 3D genome","volume":"49","author":"Gibcus","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0020","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1126\/science.1181369","article-title":"Comprehensive mapping of long-range interactions reveals folding principles of the human genome","volume":"326","author":"Lieberman-Aiden","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0025","doi-asserted-by":"crossref","first-page":"2095","DOI":"10.1051\/jphys:0198800490120209500","article-title":"The role of topological constraints in the kinetics of collapse of macromolecules","volume":"49","author":"Grosberg","year":"1988","journal-title":"J. Phys."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0030","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1007\/s10577-010-9177-0","article-title":"The fractal globule as a model of chromatin architecture in the cell","volume":"19","author":"Mirny","year":"2011","journal-title":"Chromosome Res."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0035","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.gde.2012.01.006","article-title":"Higher-order chromatin structure: bridging physics and biology","volume":"22","author":"Fudenberg","year":"2012","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0040","doi-asserted-by":"crossref","first-page":"3785","DOI":"10.1038\/emboj.2009.340","article-title":"Molecular crowding affects diffusion and binding of nuclear proteins in heterochromatin and reveals the fractal organization of chromatin","volume":"28","author":"Bancaud","year":"2009","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0045","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bbagrm.2008.07.002","article-title":"Chromatin loops in gene regulation","volume":"1789","author":"Kadauke","year":"2009","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0050","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1111\/gtc.12010","article-title":"Relationship between DNA replication and the nuclear matrix","volume":"18","author":"Wilson","year":"2013","journal-title":"Genes Cells"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0055","doi-asserted-by":"crossref","first-page":"e12218","DOI":"10.1371\/journal.pone.0012218","article-title":"Diffusion-driven looping provides a consistent framework for chromatin organization","volume":"5","author":"Bohn","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0060","doi-asserted-by":"crossref","first-page":"3712","DOI":"10.1529\/biophysj.105.077685","article-title":"Entropy-driven genome organization","volume":"90","author":"Marenduzzo","year":"2006","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0065","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.cell.2011.01.024","article-title":"Functional and mechanistic diversity of distal transcription enhancers","volume":"144","author":"Bulger","year":"2011","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0070","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nrc1991","article-title":"Polycomb silencers control cell fate, development and cancer","volume":"6","author":"Sparmann","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0075","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jmb.2009.10.031","article-title":"A model for all genomes: the role of transcription factories","volume":"395","author":"Cook","year":"2010","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0080","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1146\/annurev-cellbio-101011-155824","article-title":"Nuclear organization and genome function","volume":"28","author":"van Bortle","year":"2012","journal-title":"Annu. Rev. Cell Dev. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0085","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1038\/nature11082","article-title":"Topological domains in mammalian genomes identified by analysis of chromatin interactions","volume":"485","author":"Dixon","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0090","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.cell.2012.01.010","article-title":"Three-dimensional folding and functional organization principles of the Drosophila genome","volume":"148","author":"Sexton","year":"2012","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0095","doi-asserted-by":"crossref","first-page":"e1000889","DOI":"10.1371\/journal.pgen.1000889","article-title":"Initial genomics of the human nucleolus","volume":"6","author":"N\u00e9meth","year":"2010","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0100","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1016\/j.ceb.2010.04.002","article-title":"Genome\u2013nuclear lamina interactions and gene regulation","volume":"22","author":"Kind","year":"2010","journal-title":"Curr. Opin. Cell Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0105","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/35066075","article-title":"Chromosome territories, nuclear architecture and gene regulation in mammalian cells","volume":"2","author":"Cremer","year":"2001","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0110","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.advenzreg.2009.10.003","article-title":"The architecture of functional neighborhoods within the mammalian cell nucleus","volume":"50","author":"Malyavantham","year":"2010","journal-title":"Adv. Enzyme Regul."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0115","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1091\/mbc.11.3.799","article-title":"Half a century of \u201cthe nuclear matrix\u201d","volume":"11","author":"Pederson","year":"2000","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0120","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1007\/s004120000077","article-title":"A new look at the nuclear matrix","volume":"109","author":"Hancock","year":"2000","journal-title":"Chromosoma"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0125","doi-asserted-by":"crossref","first-page":"4133","DOI":"10.1021\/bi00012a032","article-title":"The specificity of human lymphocyte nucleolar DNA long-range fragmentation by endogenous topoisomerase II and exogenous Bal 31 nuclease depends on cell proliferation status","volume":"34","author":"Iarovaia","year":"1995","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0130","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1101\/gad.14.12.1541","article-title":"Rearrangement of chromatin domains during development in Xenopus","volume":"14","author":"Vassetzky","year":"2000","journal-title":"Genes Dev."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0135","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1242\/jcs.19.2.261","article-title":"Supercoils in human DNA","volume":"19","author":"Cook","year":"1975","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0140","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/0006-291X(84)90411-X","article-title":"Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells","volume":"123","author":"\u00d6stling","year":"1984","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0145","first-page":"179","article-title":"The comet assay. An overview of techniques, Meth","volume":"203","author":"Olive","year":"2002","journal-title":"Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0150","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1385\/MB:26:3:249","article-title":"The comet assay for DNA damage and repair: principles, applications, and limitations","volume":"26","author":"Collins","year":"2004","journal-title":"Mol. Biotechnol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0155","doi-asserted-by":"crossref","first-page":"3005","DOI":"10.1002\/elps.200700921","article-title":"Single-cell gel electrophoresis (the comet assay): loops or fragments?","volume":"29","author":"Shaposhnikov","year":"2008","journal-title":"Electrophoresis"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0160","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/S0304-4165(99)00076-8","article-title":"Effects of ethidium bromide on DNA loop organisation in human lymphocytes measured by anomalous viscosity time dependence and single cell gel electrophoresis","volume":"1428","author":"Belyaev","year":"1999","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0165","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1080\/09553000500077211","article-title":"Dose\u2013response for radiation-induced apoptosis, residual 53BP1 foci and DNA-loop relaxation in human lymphocytes","volume":"81","author":"Torudd","year":"2005","journal-title":"Int. J. Radiat. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0170","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1002\/elps.200900421","article-title":"Kinetics of comet formation in single-cell gel electrophoresis: loops and fragments","volume":"31","author":"Afanasieva","year":"2010","journal-title":"Electrophoresis"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0175","doi-asserted-by":"crossref","first-page":"3123","DOI":"10.1016\/S0021-9258(18)97296-0","article-title":"Spectrophotometric studies of the interaction of chloroquine with deoxyribonucleic acid","volume":"240","author":"Cohen","year":"1965","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0180","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1016\/0022-2836(74)90031-X","article-title":"Theoretical aspects of DNA\u2013protein interactions: cooperative and noncooperative binding of large ligands to a one-dimensional homogeneous lattice","volume":"86","author":"McGhee","year":"1974","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0185","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/elps.1150140103","article-title":"Gel electrophoresis of an end-labeled DNA. I. Dynamics and trapping in constant fields","volume":"14","author":"D\u00e9fontaines","year":"1993","journal-title":"Ectrophoresis"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0190","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0022-2836(84)90404-2","article-title":"Torsional rigidity of DNA and length dependence of the free energy of DNA supercoiling","volume":"173","author":"Horowitz","year":"1984","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0195","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1146\/annurev.bb.23.060194.003141","article-title":"Conformational and thermodynamic properties of supercoiled DNA","volume":"23","author":"Vologodskii","year":"1994","journal-title":"Annu. Rev. Biophys. Biomol. Struct."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0200","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1006\/jmbi.1998.2380","article-title":"Nucleosome dynamics II. High flexibility of nucleosome entering and exiting DNAs to positive crossing. An ethidium bromide fluorescence study of mononucleosomes on DNA minicircles","volume":"285","author":"Sivolob","year":"1999","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0205","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/0022-2836(70)90312-8","article-title":"Interaction of closed circular DNA with intercalative dyes II. The free energy of superhelix formation in SV40 DNA","volume":"47","author":"Bauer","year":"1970","journal-title":"J. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0210","doi-asserted-by":"crossref","first-page":"1613","DOI":"10.1093\/nar\/8.7.1613","article-title":"The effect of ionic strength on DNA\u2013ligand unwinding angles for acridine and quinoline derivatives","volume":"8","author":"Jones","year":"1980","journal-title":"Nucl. Acids Res."},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0215","doi-asserted-by":"crossref","first-page":"1349","DOI":"10.1002\/bip.360341007","article-title":"Effects of DNA charge and length on the electrophoretic mobility of intercalated DNA","volume":"34","author":"Reese","year":"1994","journal-title":"Biopolymers"},{"key":"10.1016\/j.bbamcr.2013.09.021_bb0220","doi-asserted-by":"crossref","first-page":"1524","DOI":"10.1002\/elps.1150171003","article-title":"The effect of ethidium bromide on mobility of DNA fragments in agarose gel electrophoresis","volume":"17","author":"Sigmon","year":"1996","journal-title":"Electrophoresis"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488913003431?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488913003431?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,3,7]],"date-time":"2022-03-07T22:54:28Z","timestamp":1646693668000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488913003431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,12]]},"references-count":44,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2013,12]]}},"alternative-id":["S0167488913003431"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2013.09.021","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2013,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DNA loop domain organization as revealed by single-cell gel electrophoresis","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2013.09.021","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2013 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}