{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T23:18:28Z","timestamp":1781911108306,"version":"3.54.5"},"reference-count":146,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,1]],"date-time":"2016-06-01T00:00:00Z","timestamp":1464739200000},"content-version":"vor","delay-in-days":366,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Czech Grant Agency","award":["P305\/14\/23986S"],"award-info":[{"award-number":["P305\/14\/23986S"]}]},{"name":"Czech Grant Agency","award":["P305\/12\/2261"],"award-info":[{"award-number":["P305\/12\/2261"]}]},{"name":"Czech Academy of Sciences","award":["M200961204"],"award-info":[{"award-number":["M200961204"]}]},{"name":"Bioglobe","award":["CZ.1.07\/2.3.00\/30.0032"],"award-info":[{"award-number":["CZ.1.07\/2.3.00\/30.0032"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1016\/j.bbamcr.2014.08.015","type":"journal-article","created":{"date-parts":[[2014,9,6]],"date-time":"2014-09-06T12:01:31Z","timestamp":1410004891000},"page":"1481-1492","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":30,"title":["Fe\/S protein biogenesis in trypanosomes \u2014 A review"],"prefix":"10.1016","volume":"1853","author":[{"given":"Julius","family":"Luke\u0161","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Somsuvro","family":"Basu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2014.08.015_bb0005","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1016\/S0140-6736(03)14694-6","article-title":"The trypanosomiases","volume":"362","author":"Barrett","year":"2003","journal-title":"Lancet"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0010","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S0140-6736(98)10178-2","article-title":"Leishmaniasis","volume":"354","author":"Herwaldt","year":"1999","journal-title":"Lancet"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0015","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0065-308X(08)60148-7","article-title":"Phytomonas and other trypanosomatid parasites of plants and fruit","volume":"42","author":"Camargo","year":"1999","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0020","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/S0169-4758(99)01498-2","article-title":"Genetic manipulation of kinetoplastida","volume":"15","author":"Clayton","year":"1999","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0025","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.molbiopara.2007.03.012","article-title":"Functional genomics in Trypanosoma brucei: a collection of vectors for the expression of tagged proteins from endogenous and ectopic gene loci","volume":"154","author":"Kelly","year":"2007","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0030","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1128\/MMBR.05024-11","article-title":"Biochemistry and evolution of anaerobic energy metabolism in eukaryotes","volume":"76","author":"M\u00fcller","year":"2012","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0035","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1098\/rstb.2009.0252","article-title":"Evolutionary origins of metabolic compartmentalization in eukaryotes","volume":"365","author":"Martin","year":"2010","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0040","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/S0092-8674(02)00653-0","article-title":"Editing machines: the complexities of trypanosome RNA editing","volume":"108","author":"Madison-Antenucci","year":"2002","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0045","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1016\/0092-8674(90)90674-4","article-title":"Trans splicing of nuclear pre-mRNAs","volume":"61","author":"Agabian","year":"1990","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0065-308X(01)49037-3","article-title":"Antigenic variation in trypanosomes: enhanced phenotypic variation in a eukaryotic parasite","volume":"49","author":"Barry","year":"2001","journal-title":"Adv. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0055","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.pt.2012.12.005","article-title":"Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story","volume":"29","author":"Baker","year":"2013","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0060","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pt.2011.10.007","article-title":"Trypanosomes and the solution to a 50-year mitochondrial calcium mystery","volume":"28","author":"Docampo","year":"2012","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0065","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1042\/BST0330967","article-title":"The extraordinary mitochondrion and unusual citric acid cycle in Trypanosoma brucei","volume":"33","author":"van Hellemond","year":"2005","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0070","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0169-4758(98)01263-0","article-title":"Differences in energy metabolism between trypanosomatidae","volume":"14","author":"Tielens","year":"1998","journal-title":"Parasitol. Today"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0075","doi-asserted-by":"crossref","first-page":"1463","DOI":"10.1016\/j.bbamcr.2006.08.019","article-title":"Metabolic functions of glycosomes in trypanosomatids","volume":"1763","author":"Michels","year":"2006","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0080","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1475-9292-2-11","article-title":"Evolution of energy metabolism and its compartmentation in Kinetoplastida","volume":"2","author":"Hannaert","year":"2003","journal-title":"Kinetoplastid Biol. Dis."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0085","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.molbiopara.2010.11.003","article-title":"Complex I (NADH:ubiquinone oxidoreductase) is active in but non-essential for procyclic Trypanosoma brucei","volume":"175","author":"Verner","year":"2011","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0090","doi-asserted-by":"crossref","first-page":"4029","DOI":"10.1038\/sj.emboj.7600862","article-title":"The F1-ATP synthase complex in bloodstream stage trypanosomes has an unusual and essential function","volume":"24","author":"Schnaufer","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0095","doi-asserted-by":"crossref","first-page":"831","DOI":"10.1038\/nature08301","article-title":"Function and biogenesis of iron-sulphur proteins","volume":"460","author":"Lill","year":"2009","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0100","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1016\/j.molbiopara.2009.05.004","article-title":"Mitochondrial carrier family inventory of Trypanosoma brucei brucei: identification, expression and subcellular localisation","volume":"167","author":"Colasante","year":"2009","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0105","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S1383-5769(99)00018-5","article-title":"The transferrin receptor of Trypanosoma brucei","volume":"48","author":"Steverding","year":"2000","journal-title":"Parasitol. Int."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0110","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1017\/S0031182009991880","article-title":"Iron metabolism in trypanosomatids, and its crucial role in infection","volume":"137","author":"Taylor","year":"2010","journal-title":"Parasitology"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0115","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1645\/GE-3237.1","article-title":"Efficient iron uptake via a reductive mechanism in procyclic Trypanosoma brucei","volume":"99","author":"Mach","year":"2013","journal-title":"J. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0120","doi-asserted-by":"crossref","first-page":"1037","DOI":"10.1016\/S0891-5849(02)01006-7","article-title":"The labile iron pool: characterization, measurement, and participation in cellular processes(1)","volume":"33","author":"Kakhlon","year":"2002","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0125","series-title":"Iron metabolism in pathogenic trypanosomes, Iron metabolism","isbn-type":"print","author":"Manta","year":"2012","ISBN":"https:\/\/id.crossref.org\/isbn\/9789535106050"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0130","doi-asserted-by":"crossref","first-page":"4815","DOI":"10.1093\/emboj\/cdg446","article-title":"Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p","volume":"22","author":"M\u00fchlenhoff","year":"2003","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0135","doi-asserted-by":"crossref","first-page":"5675","DOI":"10.1128\/MCB.00112-06","article-title":"Role of human mitochondrial Nfs1 in cytosolic iron-sulfur protein biogenesis and iron regulation","volume":"26","author":"Biederbick","year":"2006","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0140","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1021\/ja308736e","article-title":"Mammalian frataxin controls sulfur production and iron entry during de novo Fe4S4 cluster assembly","volume":"135","author":"Colin","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0145","doi-asserted-by":"crossref","first-page":"a011312","DOI":"10.1101\/cshperspect.a011312","article-title":"The role of mitochondria in cellular iron-sulfur protein biogenesis: mechanisms, connected processes, and diseases","volume":"5","author":"Stehling","year":"2013","journal-title":"Cold Spring Harb. Perspect. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0150","doi-asserted-by":"crossref","first-page":"1050","DOI":"10.1073\/pnas.97.3.1050","article-title":"A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins","volume":"97","author":"Lange","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0155","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1091\/mbc.E12-09-0644","article-title":"The mitochondrial Hsp70 chaperone Ssq1 facilitates Fe\/S cluster transfer from Isu1 to Grx5 by complex formation","volume":"24","author":"Uzarska","year":"2013","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0160","doi-asserted-by":"crossref","first-page":"22604","DOI":"10.1074\/jbc.M102902200","article-title":"Iron-sulfur cluster assembly: characterization of IscA and evidence for a specific and functional complex with ferredoxin","volume":"276","author":"Ollagnier-de-Choudens","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0165","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1007\/s00775-001-0330-2","article-title":"Iron-sulfur cluster biosynthesis: characterization of Schizosaccharomyces pombe Isa1","volume":"7","author":"Wu","year":"2002","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0170","doi-asserted-by":"crossref","first-page":"41205","DOI":"10.1074\/jbc.M111.296152","article-title":"Specialized function of yeast Isa1 and Isa2 proteins in the maturation of mitochondrial [4Fe-4S] proteins","volume":"286","author":"M\u00fchlenhoff","year":"2011","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0175","doi-asserted-by":"crossref","first-page":"6059","DOI":"10.1128\/MCB.00817-09","article-title":"Human ind1, an iron-sulfur cluster assembly factor for respiratory complex I","volume":"29","author":"Sheftel","year":"2009","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0180","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/j.ajhg.2011.08.011","article-title":"Mutations in iron-sulfur cluster scaffold genes NFU1 and BOLA3 cause a fatal deficiency of multiple respiratory chain and 2-oxoacid dehydrogenase enzymes","volume":"89","author":"Cameron","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0185","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.ajhg.2011.10.005","article-title":"A fatal mitochondrial disease is associated with defective NFU1 function in the maturation of a subset of mitochondrial Fe-S proteins","volume":"89","author":"Navarro-Sastre","year":"2011","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0190","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1126\/science.1112642","article-title":"The genome of the African trypanosome Trypanosoma brucei","volume":"309","author":"Berriman","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0195","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1126\/science.1112631","article-title":"The genome sequence of Trypanosoma cruzi, etiologic agent of Chagas disease","volume":"309","author":"El-Sayed","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0200","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.1112680","article-title":"The genome of the kinetoplastid parasite, Leishmania major","volume":"309","author":"Ivens","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0205","doi-asserted-by":"crossref","first-page":"D457","DOI":"10.1093\/nar\/gkp851","article-title":"TriTrypDB: a functional genomic resource for the Trypanosomatidae","volume":"38","author":"Aslett","year":"2010","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0210","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1016\/S0020-7519(01)00296-X","article-title":"Unique aspects of mitochondrial biogenesis in trypanosomatids","volume":"31","author":"Schneider","year":"2001","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0215","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.pt.2006.08.007","article-title":"Trypanosome alternative oxidase: from molecule to function","volume":"22","author":"Chaudhuri","year":"2006","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0220","doi-asserted-by":"crossref","first-page":"28679","DOI":"10.1074\/jbc.M513781200","article-title":"Knock-downs of iron-sulfur cluster assembly proteins IscS and IscU down-regulate the active mitochondrion of procyclic Trypanosoma brucei","volume":"281","author":"Sm\u00edd","year":"2006","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0225","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1016\/S0166-6851(02)00238-4","article-title":"Targeting of a tetracycline-inducible expression system to the transcriptionally silent minichromosomes of Trypanosoma brucei","volume":"125","author":"Wickstead","year":"2002","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0230","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1074\/jbc.275.4.2745","article-title":"A developmentally regulated aconitase related to iron-regulatory protein-1 is localized in the cytoplasm and in the mitochondrion of Trypanosoma brucei","volume":"275","author":"Saas","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0235","doi-asserted-by":"crossref","first-page":"36906","DOI":"10.1074\/jbc.M406516200","article-title":"Functional characterization of the eukaryotic cysteine desulfurase Nfs1p from Saccharomyces cerevisiae","volume":"279","author":"M\u00fchlenhoff","year":"2004","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0240","doi-asserted-by":"crossref","first-page":"4848","DOI":"10.1128\/MCB.24.11.4848-4857.2004","article-title":"The yeast scaffold proteins Isu1p and Isu2p are required inside mitochondria for maturation of cytosolic Fe\/S proteins","volume":"24","author":"Gerber","year":"2004","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0245","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1128\/EC.00235-13","article-title":"Mitochondrial and nucleolar localization of cysteine desulfurase Nfs and the scaffold protein Isu in Trypanosoma brucei","volume":"13","author":"Kov\u00e1\u0159ov\u00e1","year":"2014","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0250","doi-asserted-by":"crossref","first-page":"30200","DOI":"10.1074\/jbc.M109.034694","article-title":"Dual targeting of Nfs1 and discovery of its novel processing enzyme, Icp55","volume":"284","author":"Naamati","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0255","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/208762a0","article-title":"Polymorphism and mitochondrial activity in sleeping sickness trypanosomes","volume":"208","author":"Vickerman","year":"1965","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0260","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1111\/j.1742-4658.2009.07489.x","article-title":"Functions and cellular localization of cysteine desulfurase and selenocysteine lyase in Trypanosoma brucei","volume":"277","author":"Poliak","year":"2010","journal-title":"FEBS J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0265","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s00253-002-1107-4","article-title":"Bacterial cysteine desulfurases: their function and mechanisms","volume":"60","author":"Mihara","year":"2002","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0270","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1074\/jbc.R800045200","article-title":"Selenoproteins","volume":"284","author":"Lu","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0275","doi-asserted-by":"crossref","first-page":"23947","DOI":"10.1074\/jbc.M109.029421","article-title":"Thiolation controls cytoplasmic tRNA stability and acts as a negative determinant for tRNA editing in mitochondria","volume":"284","author":"Wohlgamuth-Benedum","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0280","doi-asserted-by":"crossref","first-page":"22394","DOI":"10.1074\/jbc.M109.083774","article-title":"The Fe\/S cluster assembly protein Isd11 is essential for tRNA thiolation in Trypanosoma brucei","volume":"285","author":"Paris","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jns.2011.01.010","article-title":"Friedreich's ataxia: pathology, pathogenesis, and molecular genetics","volume":"303","author":"Koeppen","year":"2011","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0290","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/jnc.12220","article-title":"Frataxin: a protein in search for a function","volume":"126","author":"Pastore","year":"2013","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0295","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1080\/10409230600846058","article-title":"The structure and function of frataxin","volume":"41","author":"Bencze","year":"2006","journal-title":"Crit. Rev. Biochem. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0300","doi-asserted-by":"crossref","first-page":"6798","DOI":"10.1021\/bi025566+","article-title":"Physical evidence that yeast frataxin is an iron storage protein","volume":"41","author":"Gakh","year":"2002","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0305","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1089\/ars.2006.8.506","article-title":"Frataxin, iron-sulfur clusters, heme, ROS, and aging","volume":"8","author":"Napoli","year":"2006","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0310","doi-asserted-by":"crossref","first-page":"1096","DOI":"10.1038\/sj.embor.7400272","article-title":"Iron-induced oligomerization of yeast frataxin homologue Yfh1 is dispensable in vivo","volume":"5","author":"Aloria","year":"2004","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0315","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1111\/j.1365-2958.2008.06260.x","article-title":"Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologues in trypanosomes","volume":"69","author":"Long","year":"2008","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0320","doi-asserted-by":"crossref","first-page":"7767","DOI":"10.1021\/bi060424r","article-title":"Monomeric yeast frataxin is an iron-binding protein","volume":"45","author":"Cook","year":"2006","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0325","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1093\/hmg\/11.16.1865","article-title":"A structural approach to understanding the iron-binding properties of phylogenetically different frataxins","volume":"11","author":"Adinolfi","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0330","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.ijpara.2009.11.007","article-title":"Evolution of the haem synthetic pathway in kinetoplastid flagellates: an essential pathway that is not essential after all?","volume":"40","author":"Ko\u0159en\u00fd","year":"2010","journal-title":"Int. J. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0335","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S0959-437X(98)80029-4","article-title":"Early branching eukaryotes?","volume":"8","author":"Embley","year":"1998","journal-title":"Curr. Opin. Genet. Dev."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0340","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1128\/EC.00027-07","article-title":"Frataxin, a conserved mitochondrial protein, in the hydrogenosome of Trichomonas vaginalis","volume":"6","author":"Dole\u017eal","year":"2007","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0345","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.tcb.2007.09.009","article-title":"The direct route: a simplified pathway for protein import into the mitochondrion of trypanosomes","volume":"18","author":"Schneider","year":"2008","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0350","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1093\/molbev\/msn288","article-title":"The single mitochondrial porin of Trypanosoma brucei is the main metabolite transporter in the outer mitochondrial membrane","volume":"26","author":"Pusnik","year":"2009","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0355","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1098\/rsbl.2009.0948","article-title":"Kingdoms Protozoa and Chromista and the eozoan root of the eukaryotic tree","volume":"6","author":"Cavalier-Smith","year":"2010","journal-title":"Biol. Lett."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0360","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.molbiopara.2008.08.001","article-title":"The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei","volume":"162","author":"Long","year":"2008","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0365","doi-asserted-by":"crossref","first-page":"13468","DOI":"10.1073\/pnas.0806762105","article-title":"Mitochondrial localization of human frataxin is necessary but processing is not for rescuing frataxin deficiency in Trypanosoma brucei","volume":"105","author":"Long","year":"2008","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0370","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1146\/annurev.biochem.76.052705.162653","article-title":"Maturation of iron-sulfur proteins in eukaryotes: mechanisms, connected processes, and diseases","volume":"77","author":"Lill","year":"2008","journal-title":"Annu. Rev. Biochem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0375","doi-asserted-by":"crossref","first-page":"2651","DOI":"10.1093\/hmg\/ddm163","article-title":"Frataxin is essential for extramitochondrial Fe-S cluster proteins in mammalian tissues","volume":"16","author":"Martelli","year":"2007","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0380","doi-asserted-by":"crossref","first-page":"3917","DOI":"10.1242\/jcs.02516","article-title":"Extra-mitochondrial localisation of frataxin and its association with IscU1 during enterocyte-like differentiation of the human colon adenocarcinoma cell line Caco-2","volume":"118","author":"Acquaviva","year":"2005","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0385","doi-asserted-by":"crossref","first-page":"e47847","DOI":"10.1371\/journal.pone.0047847","article-title":"Novel frataxin isoforms may contribute to the pathological mechanism of Friedreich ataxia","volume":"7","author":"Xia","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0390","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.abb.2007.12.014","article-title":"Iron-sulfur cluster biosynthesis in bacteria: mechanisms of cluster assembly and transfer","volume":"474","author":"Fontecave","year":"2008","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0395","doi-asserted-by":"crossref","first-page":"35297","DOI":"10.1074\/jbc.M109.040014","article-title":"Human ISCA1 interacts with IOP1\/NARFL and functions in both cytosolic and mitochondrial iron-sulfur protein biogenesis","volume":"284","author":"Song","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0400","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1111\/j.1365-2958.2011.07769.x","article-title":"Stage-specific requirement for Isa1 and Isa2 proteins in the mitochondrion of Trypanosoma brucei and heterologous rescue by human and Blastocystis orthologues","volume":"81","author":"Long","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0405","doi-asserted-by":"crossref","first-page":"1851","DOI":"10.1128\/MCB.01963-07","article-title":"Mitochondrial Iba57p is required for Fe\/S cluster formation on aconitase and activation of radical SAM enzymes","volume":"28","author":"Gelling","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0410","doi-asserted-by":"crossref","first-page":"10412","DOI":"10.1073\/pnas.0911586107","article-title":"A role for tetrahydrofolates in the metabolism of iron-sulfur clusters in all domains of life","volume":"107","author":"Waller","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0415","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1016\/j.bbamcr.2011.11.002","article-title":"Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis","volume":"1823","author":"Shi","year":"2012","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0420","doi-asserted-by":"crossref","first-page":"11775","DOI":"10.1073\/pnas.1004250107","article-title":"Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe\/S cluster biosynthesis","volume":"107","author":"Sheftel","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0425","first-page":"1","article-title":"Both human ferredoxins equally efficiently rescue ferredoxin deficiency in Trypanosoma brucei","author":"Changmai","year":"2013","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0430","doi-asserted-by":"crossref","first-page":"1660","DOI":"10.1016\/j.cub.2006.06.069","article-title":"Evolution of mitochondrial chaperones utilized in Fe-S cluster biogenesis","volume":"16","author":"Schilke","year":"2006","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0435","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0014-5793(00)02364-4","article-title":"Ecm10, a novel hsp70 homolog in the mitochondrial matrix of the yeast Saccharomyces cerevisiae","volume":"487","author":"Baumann","year":"2000","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0440","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.cell.2006.04.014","article-title":"Molecular chaperones and protein quality control","volume":"125","author":"Bukau","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0445","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/sj.emboj.7600580","article-title":"Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1","volume":"24","author":"Sichting","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0450","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1379\/CSC-231R.1","article-title":"Hsp70 may protect cardiomyocytes from stress-induced injury by inhibiting Fas-mediated apoptosis","volume":"12","author":"Zhao","year":"2007","journal-title":"Cell Stress Chaperones"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0455","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1091\/mbc.01-10-0517","article-title":"Grx5 is a mitochondrial glutaredoxin required for the activity of iron\/sulfur enzymes","volume":"13","author":"Rodr\u00edguez-Manzaneque","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0460","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.tibs.2009.08.005","article-title":"Glutaredoxins: roles in iron homeostasis","volume":"35","author":"Rouhier","year":"2010","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0465","doi-asserted-by":"crossref","first-page":"8180","DOI":"10.1128\/MCB.19.12.8180","article-title":"Grx5 glutaredoxin plays a central role in protection against protein oxidative damage in Saccharomyces cerevisiae","volume":"19","author":"Rodr\u00edguez-Manzaneque","year":"1999","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0470","doi-asserted-by":"crossref","first-page":"27785","DOI":"10.1074\/jbc.M802010200","article-title":"Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes","volume":"283","author":"Comini","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0475","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1089\/ars.2012.4859","article-title":"Iron-sulfur cluster binding by mitochondrial monothiol glutaredoxin-1 of Trypanosoma brucei: molecular basis of iron-sulfur cluster coordination and relevance for parasite infectivity","volume":"19","author":"Manta","year":"2013","journal-title":"Antioxid. Redox Signal."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0480","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1515\/BC.2007.147","article-title":"Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1","volume":"389","author":"Filser","year":"2008","journal-title":"Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0485","article-title":"(1)H, (13)C and (15)N resonance assignment of the mature form of monothiol glutaredoxin 1 from the pathogen Trypanosoma brucei","author":"Sturlese","year":"2014","journal-title":"Biomol. NMR Assign."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0490","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1042\/bj1880643","article-title":"Deficient metabolic utilization of hydrogen peroxide in Trypanosoma cruzi","volume":"188","author":"Boveris","year":"1980","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0495","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1126\/science.3883489","article-title":"Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids","volume":"227","author":"Fairlamb","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0500","doi-asserted-by":"crossref","first-page":"3199","DOI":"10.1016\/j.bbagen.2013.01.013","article-title":"Trypanothione: a unique bis-glutathionyl derivative in trypanosomatids","volume":"1830","author":"Manta","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0505","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1046\/j.1365-2958.2000.01721.x","article-title":"Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress","volume":"35","author":"Krieger","year":"2000","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0510","doi-asserted-by":"crossref","first-page":"35224","DOI":"10.1074\/jbc.M110.165860","article-title":"The dithiol glutaredoxins of african trypanosomes have distinct roles and are closely linked to the unique trypanothione metabolism","volume":"285","author":"Ceylan","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0515","doi-asserted-by":"crossref","first-page":"1137","DOI":"10.1126\/science.1246729","article-title":"Crystal structures of nucleotide-free and glutathione-bound mitochondrial ABC transporter Atm1","volume":"343","author":"Srinivasan","year":"2014","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0520","doi-asserted-by":"crossref","first-page":"3981","DOI":"10.1093\/emboj\/18.14.3981","article-title":"The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe\/S proteins","volume":"18","author":"Kispal","year":"1999","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0525","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1093\/embo-reports\/kve161","article-title":"An essential function of the mitochondrial sulfhydryl oxidase Erv1p\/ALR in the maturation of cytosolic Fe\/S proteins","volume":"2","author":"Lange","year":"2001","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0530","doi-asserted-by":"crossref","first-page":"26944","DOI":"10.1074\/jbc.M200677200","article-title":"Maturation of cytosolic iron-sulfur proteins requires glutathione","volume":"277","author":"Sipos","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0535","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.tibs.2005.01.006","article-title":"Iron-sulfur-protein biogenesis in eukaryotes","volume":"30","author":"Lill","year":"2005","journal-title":"Trends Biochem. Sci."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0540","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1128\/EC.00304-12","article-title":"Divergence of Erv1-associated mitochondrial import and export pathways in trypanosomes and anaerobic protists","volume":"12","author":"Basu","year":"2013","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0545","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1016\/j.cell.2005.04.011","article-title":"A disulfide relay system in the intermembrane space of mitochondria that mediates protein import","volume":"121","author":"Mesecke","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0550","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1038\/nsmb.1553","article-title":"MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria","volume":"16","author":"Banci","year":"2009","journal-title":"Nat. Struct. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0555","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.1016\/j.febslet.2008.07.015","article-title":"Distinctive biochemistry in the trypanosome mitochondrial intermembrane space suggests a model for stepwise evolution of the MIA pathway for import of cysteine-rich proteins","volume":"582","author":"Allen","year":"2008","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0560","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.bbamcr.2007.12.005","article-title":"The Erv1-Mia40 disulfide relay system in the intermembrane space of mitochondria","volume":"1783","author":"Hell","year":"2008","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0565","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/S0065-2911(05)50005-5","article-title":"Energy metabolism and its compartmentation in Trypanosoma brucei","volume":"50","author":"van Hellemond","year":"2005","journal-title":"Adv. Microb. Physiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0570","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1021\/bi0479555","article-title":"Augmenter of liver regeneration: A flavin-dependent sulfhydryl oxidase with cytochrome c reductase activity","volume":"44","author":"Farrell","year":"2005","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0575","doi-asserted-by":"crossref","first-page":"4801","DOI":"10.1038\/sj.emboj.7601909","article-title":"A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1","volume":"26","author":"Dabir","year":"2007","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0580","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1042\/BJ20130442","article-title":"Identification and characterization of mitochondrial Mia40 as an iron-sulfur protein","volume":"455","author":"Spiller","year":"2013","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0585","doi-asserted-by":"crossref","first-page":"3228","DOI":"10.1073\/pnas.1015953108","article-title":"Ribosome recycling depends on a mechanistic link between the FeS cluster domain and a conformational switch of the twin-ATPase ABCE1","volume":"108","author":"Barthelme","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0590","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nchembio.721","article-title":"Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes","volume":"8","author":"Netz","year":"2011","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0595","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.sbi.2011.11.004","article-title":"Iron-sulphur clusters in nucleic acid processing enzymes","volume":"22","author":"White","year":"2012","journal-title":"Curr. Opin. Struct. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0600","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1016\/j.molcel.2006.07.019","article-title":"The DNA repair helicases XPD and FancJ have essential iron-sulfur domains","volume":"23","author":"Rudolf","year":"2006","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0605","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1126\/science.1219723","article-title":"MMS19 assembles iron-sulfur proteins required for DNA metabolism and genomic integrity","volume":"337","author":"Stehling","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0610","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1126\/science.1219664","article-title":"MMS19 links cytoplasmic iron-sulfur cluster assembly to DNA metabolism","volume":"337","author":"Gari","year":"2012","journal-title":"Science"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0615","article-title":"Maturation of cytosolic and nuclear iron-sulfur proteins","author":"Netz","year":"2013","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0620","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1038\/nchembio872","article-title":"The Cfd1-Nbp35 complex acts as a scaffold for iron-sulfur protein assembly in the yeast cytosol","volume":"3","author":"Netz","year":"2007","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0625","doi-asserted-by":"crossref","first-page":"12365","DOI":"10.1074\/jbc.M111.328914","article-title":"A bridging [4Fe-4S] cluster and nucleotide binding are essential for function of the Cfd1-Nbp35 complex as a scaffold in iron-sulfur protein maturation","volume":"287","author":"Netz","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0630","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1038\/nchembio.432","article-title":"Tah18 transfers electrons to Dre2 in cytosolic iron-sulfur protein biogenesis","volume":"6","author":"Netz","year":"2010","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0635","doi-asserted-by":"crossref","first-page":"2105","DOI":"10.1038\/sj.emboj.7600216","article-title":"The hydrogenase-like Nar1p is essential for maturation of cytosolic and nuclear iron\u2013sulphur proteins","volume":"23","author":"Balk","year":"2004","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0640","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.cmet.2013.06.015","article-title":"Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins","volume":"18","author":"Stehling","year":"2013","journal-title":"Cell Metab."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0645","doi-asserted-by":"crossref","first-page":"1246","DOI":"10.1016\/j.str.2007.08.009","article-title":"Structure of the yeast WD40 domain protein Cia1, a component acting late in iron-sulfur protein biogenesis","volume":"15","author":"Srinivasan","year":"2007","journal-title":"Structure"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0650","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1128\/EC.00158-13","article-title":"Evolution of the cytosolic iron-sulfur cluster assembly machinery in Blastocystis species and other microbial eukaryotes","volume":"13","author":"Tsaousis","year":"2014","journal-title":"Eukaryot. Cell"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0655","doi-asserted-by":"crossref","first-page":"e4376","DOI":"10.1371\/journal.pone.0004376","article-title":"A newly identified essential complex, Dre2-Tah18, controls mitochondria integrity and cell death after oxidative stress in yeast","volume":"4","author":"Vernis","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0660","doi-asserted-by":"crossref","first-page":"e17285","DOI":"10.1371\/journal.pone.0017285","article-title":"The minimal proteome in the reduced mitochondrion of the parasitic protist Giardia intestinalis","volume":"6","author":"Jedelsk\u00fd","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0665","doi-asserted-by":"crossref","first-page":"897","DOI":"10.1111\/mmi.12706","article-title":"Cytosolic iron-sulfur protein assembly is functionally conserved and essential in procyclic and bloodstream Trypanosoma brucei","volume":"93","author":"Basu","year":"2014","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0670","doi-asserted-by":"crossref","first-page":"2108","DOI":"10.1111\/j.1742-4658.2012.08597.x","article-title":"A S-adenosylmethionine methyltransferase-like domain within the essential, Fe-S-containing yeast protein Dre2","volume":"279","author":"Soler","year":"2012","journal-title":"FEBS J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0675","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1111\/j.1365-2958.2011.07788.x","article-title":"Interaction between the reductase Tah18 and highly conserved Fe-S containing Dre2 C-terminus is essential for yeast viability.","volume":"82","author":"Soler","year":"2011","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0680","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s00775-013-1033-1","article-title":"Human anamorsin binds [2Fe-2S] clusters with unique electronic properties","volume":"18","author":"Banci","year":"2013","journal-title":"J. Biol. Inorg. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0685","doi-asserted-by":"crossref","first-page":"16561","DOI":"10.1021\/bi991119r","article-title":"IscS is a sulfurtransferase for the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA","volume":"38","author":"Kambampati","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0690","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1016\/j.pt.2011.02.003","article-title":"Assembling Fe\/S-clusters and modifying tRNAs: ancient co-factors meet ancient adaptors","volume":"27","author":"Alfonzo","year":"2011","journal-title":"Trends Parasitol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0695","doi-asserted-by":"crossref","first-page":"5427","DOI":"10.1093\/nar\/17.14.5427","article-title":"Kinetoplastid mitochondria contain functional tRNAs which are encoded in nuclear DNA and also contain small minicircle and maxicircle transcripts of unknown function","volume":"17","author":"Simpson","year":"1989","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0700","doi-asserted-by":"crossref","first-page":"36491","DOI":"10.1074\/jbc.M109.064527","article-title":"Thiolated tRNAs of Trypanosoma brucei are imported into mitochondria and dethiolated after import","volume":"284","author":"Bruske","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0705","doi-asserted-by":"crossref","first-page":"e1000354","DOI":"10.1371\/journal.pbio.1000354","article-title":"Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions","volume":"8","author":"Shi","year":"2010","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0710","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1128\/MCB.01321-06","article-title":"Thio modification of yeast cytosolic tRNA is an iron-sulfur protein-dependent pathway","volume":"27","author":"Nakai","year":"2007","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0715","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1038\/sj.emboj.7601105","article-title":"Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA","volume":"25","author":"Noma","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0720","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1261\/rna.7247705","article-title":"An early step in wobble uridine tRNA modification requires the Elongator complex","volume":"11","author":"Huang","year":"2005","journal-title":"RNA"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0725","doi-asserted-by":"crossref","first-page":"5140","DOI":"10.1021\/bi7000449","article-title":"MiaB, a bifunctional radical-S-adenosylmethionine enzyme involved in the thiolation and methylation of tRNA, contains two essential [4Fe-4S] clusters","volume":"46","author":"Hern\u00e1ndez","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2014.08.015_bb0730","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1111\/j.1365-2958.2010.07368.x","article-title":"Mitochondrial translation is essential in bloodstream forms of Trypanosoma brucei","volume":"78","author":"Cristodero","year":"2010","journal-title":"Mol. Microbiol."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488914003243?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488914003243?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,29]],"date-time":"2018-09-29T21:25:40Z","timestamp":1538256340000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488914003243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":146,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S0167488914003243"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2014.08.015","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Fe\/S protein biogenesis in trypanosomes \u2014 A review","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2014.08.015","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}