{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,22]],"date-time":"2025-11-22T11:05:55Z","timestamp":1763809555337},"reference-count":46,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2017,8,1]],"date-time":"2017-08-01T00:00:00Z","timestamp":1501545600000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.bbamcr.2016.05.003","type":"journal-article","created":{"date-parts":[[2016,5,5]],"date-time":"2016-05-05T23:24:47Z","timestamp":1462490687000},"page":"1979-1984","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"title":["Altered expression of Mg2+ transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells"],"prefix":"10.1016","volume":"1863","author":[{"given":"Yutaka","family":"Shindo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryu","family":"Yamanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koji","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kohji","family":"Hotta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kotaro","family":"Oka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2016.05.003_bb0005","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.1016\/S0140-6736(09)60492-X","article-title":"Parkinson's disease","volume":"373","author":"Lees","year":"2009","journal-title":"Lancet"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0010","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S1474-4422(06)70471-9","article-title":"Epidemiology of Parkinson's disease","volume":"5","author":"de Lau","year":"2006","journal-title":"Lancet Neurol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0015","doi-asserted-by":"crossref","first-page":"461","DOI":"10.3233\/JPD-130230","article-title":"The role of oxidative stress in Parkinson's disease","volume":"3","author":"Dias","year":"2013","journal-title":"J. Parkinsons Dis."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0020","doi-asserted-by":"crossref","first-page":"1401","DOI":"10.1136\/bmj.289.6456.1401","article-title":"MPTP parkinsonism","volume":"289","author":"Williams","year":"1984","journal-title":"Br. Med. J. (Clin. Res. Ed.)"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0025","doi-asserted-by":"crossref","first-page":"1403","DOI":"10.1038\/70978","article-title":"Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease","volume":"5","author":"Liberatore","year":"1999","journal-title":"Nat. Med."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0030","first-page":"617472","article-title":"Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection","volume":"2011","author":"Mounsey","year":"2011","journal-title":"Parkinsons Dis."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0035","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1073\/pnas.82.7.2173","article-title":"Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity","volume":"82","author":"Javitch","year":"1985","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0040","doi-asserted-by":"crossref","first-page":"1184","DOI":"10.1111\/j.1471-4159.1991.tb11409.x","article-title":"Interaction of 1-methyl-4-phenylpyridinium ion (MPP+) and its analogs with the rotenone\/piericidin binding site of NADH dehydrogenase","volume":"56","author":"Ramsay","year":"1991","journal-title":"J. Neurochem."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0045","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.brainres.2007.12.033","article-title":"Magnesium exerts both preventive and ameliorating effects in an in vitro rat Parkinson disease model involving 1-methyl-4-phenylpyridinium (MPP+) toxicity in dopaminergic neurons","volume":"1197","author":"Hashimoto","year":"2008","journal-title":"Brain Res."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0050","doi-asserted-by":"crossref","first-page":"3182","DOI":"10.1016\/j.bbamcr.2015.08.013","article-title":"Intracellular magnesium level determines cell viability in the MPP+ model of Parkinson's disease","volume":"1853","author":"Shindo","year":"2015","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1152\/physrev.00012.2014","article-title":"Magnesium in man: implications for health and disease","volume":"95","author":"de Baaij","year":"2015","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0060","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.abb.2011.05.010","article-title":"Cellular magnesium homeostasis","volume":"512","author":"Romani","year":"2011","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0065","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1042\/CS20070129","article-title":"Cell (patho)physiology of magnesium","volume":"114","author":"Wolf","year":"2008","journal-title":"Clin. Sci. (Lond.)"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0070","doi-asserted-by":"crossref","first-page":"C407","DOI":"10.1152\/ajpcell.00124.2009","article-title":"Molecular identification of ancient and modern mammalian magnesium transporters","volume":"298","author":"Quamme","year":"2010","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0075","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1038\/ncomms1108","article-title":"TRPM7 is essential for Mg2+ homeostasis in mammals","volume":"1","author":"Ryazanova","year":"2010","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0080","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/S0006-291X(03)00346-2","article-title":"Na+\/Mg2+ transporter acts as a Mg2+ buffering mechanism in PC12 cells","volume":"303","author":"Kubota","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0085","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.bbamcr.2004.10.013","article-title":"Mitochondria are intracellular magnesium stores: investigation by simultaneous fluorescent imagings in PC12 cells","volume":"1744","author":"Kubota","year":"2005","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0090","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1016\/S0006-3495(01)76104-8","article-title":"Apparent intracellular Mg2+ buffering in neurons of the leech Hirudo medicinalis","volume":"80","author":"Gunzel","year":"2001","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0095","first-page":"231","article-title":"Mg-ATP binding: its modification by spermine, the relevance to cytosolic Mg2+ buffering, changes in the intracellular ionized Mg2+ concentration and the estimation of Mg2+ by 31P-NMR","volume":"84","author":"Luthi","year":"1999","journal-title":"Exp. Physiol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0100","doi-asserted-by":"crossref","first-page":"e1004267","DOI":"10.1371\/journal.pgen.1004267","article-title":"CNNM2 mutations cause impaired brain development and seizures in patients with hypomagnesemia","volume":"10","author":"Arjona","year":"2014","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0105","doi-asserted-by":"crossref","first-page":"11510","DOI":"10.1073\/pnas.0505149102","article-title":"A TRPM7 variant shows altered sensitivity to magnesium that may contribute to the pathogenesis of two Guamanian neurodegenerative disorders","volume":"102","author":"Hermosura","year":"2005","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0110","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1016\/j.bbadis.2007.02.008","article-title":"TRPM7 and TRPM2-candidate susceptibility genes for western Pacific ALS and PD?","volume":"1772","author":"Hermosura","year":"2007","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0115","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1016\/j.parkreldis.2014.02.027","article-title":"Variant R244H in Na+\/Mg2+ exchanger SLC41A1 in Taiwanese Parkinson's disease is associated with loss of Mg2+ efflux function","volume":"20","author":"Lin","year":"2014","journal-title":"Parkinsonism Relat. Disord."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0120","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1038\/jhg.2015.34","article-title":"Fine mapping and resequencing of the PARK16 locus in Parkinson's disease","volume":"60","author":"Pihlstrom","year":"2015","journal-title":"J. Hum. Genet."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0125","doi-asserted-by":"crossref","first-page":"C318","DOI":"10.1152\/ajpcell.00289.2011","article-title":"Human gene SLC41A1 encodes for the Na+\/Mg2+ exchanger","volume":"302","author":"Kolisek","year":"2011","journal-title":"Am. J. Physiol. Cell Physiol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0130","first-page":"593","article-title":"Calcium, magnesium and aluminum concentrations in Parkinson's disease","volume":"13","author":"Yasui","year":"1992","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0135","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/j.jtemb.2005.08.003","article-title":"Calcium, copper, iron, magnesium, silicon and zinc content of hair in Parkinson's disease","volume":"19","author":"Forte","year":"2005","journal-title":"J. Trace Elem. Med. Biol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0140","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.neuroscience.2015.10.001","article-title":"Neural depolarization triggers Mg2+ influx in rat hippocampal neurons","volume":"310","author":"Yamanaka","year":"2015","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0145","doi-asserted-by":"crossref","first-page":"3125","DOI":"10.1002\/jnr.22467","article-title":"Glutamate-induced calcium increase mediates magnesium release from mitochondria in rat hippocampal neurons","volume":"88","author":"Shindo","year":"2010","journal-title":"J. Neurosci. Res."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0150","doi-asserted-by":"crossref","first-page":"2643","DOI":"10.1016\/j.febslet.2013.06.049","article-title":"NO\/cGMP\/PKG signaling pathway induces magnesium release mediated by mitoKATP channel opening in rat hippocampal neurons","volume":"587","author":"Yamanaka","year":"2013","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0155","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0160","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/j.bbrc.2005.03.037","article-title":"Functional characterization of the human solute carrier, SLC41A2","volume":"330","author":"Goytain","year":"2005","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0165","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1152\/physiolgenomics.00058.2005","article-title":"Functional characterization of ACDP2 (ancient conserved domain protein), a divalent metal transporter","volume":"22","author":"Goytain","year":"2005","journal-title":"Physiol. Genomics"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0170","doi-asserted-by":"crossref","first-page":"8060","DOI":"10.1074\/jbc.M610314200","article-title":"NIPA1(SPG6), the basis for autosomal dominant form of hereditary spastic paraplegia, encodes a functional Mg2+ transporter","volume":"282","author":"Goytain","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0175","doi-asserted-by":"crossref","first-page":"13644","DOI":"10.1074\/jbc.M112.342204","article-title":"Membrane topology and intracellular processing of cyclin M2 (CNNM2)","volume":"287","author":"de Baaij","year":"2012","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0180","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.bbapap.2003.11.015","article-title":"A kinetic approach towards understanding substrate interactions and the catalytic mechanism of the serine\/threonine protein kinase ERK2: identifying a potential regulatory role for divalent magnesium","volume":"1697","author":"Waas","year":"2004","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0185","doi-asserted-by":"crossref","first-page":"H319","DOI":"10.1152\/ajpheart.00453.2011","article-title":"Short-term magnesium deficiency upregulates ceramide synthase in cardiovascular tissues and cells: cross-talk among cytokines, Mg2+, NF-kappaB, and de novo ceramide","volume":"302","author":"Altura","year":"2012","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0190","doi-asserted-by":"crossref","first-page":"1113","DOI":"10.1111\/ejn.12872","article-title":"Evidence for a common biological pathway linking three Parkinson's disease-causing genes: parkin, PINK1 and DJ-1","volume":"41","author":"van der Merwe","year":"2015","journal-title":"Eur. J. Neurosci."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0195","doi-asserted-by":"crossref","first-page":"12849","DOI":"10.1021\/bi960139f","article-title":"Mg2+ control of respiration in isolated rat liver mitochondria","volume":"35","author":"Panov","year":"1996","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0200","doi-asserted-by":"crossref","first-page":"7850","DOI":"10.1074\/jbc.273.14.7850","article-title":"Modulation of oxidative phosphorylation by Mg2+ in rat heart mitochondria","volume":"273","author":"Rodriguez-Zavala","year":"1998","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0205","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1042\/BJ20110807","article-title":"SLC41A1 Mg2+ transport is regulated via Mg2+-dependent endosomal recycling through its N-terminal cytoplasmic domain","volume":"439","author":"Mandt","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0210","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1038\/35079092","article-title":"LTRPC7 is a Mg.ATP-regulated divalent cation channel required for cell viability","volume":"411","author":"Nadler","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0215","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.mam.2012.05.012","article-title":"The SLC41 family of MgtE-like magnesium transporters","volume":"34","author":"Sahni","year":"2013","journal-title":"Mol. Asp. Med."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0220","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1042\/BJ20060673","article-title":"SLC41A2 encodes a plasma-membrane Mg2+ transporter","volume":"401","author":"Sahni","year":"2007","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0225","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1042\/BJ20101678","article-title":"TRPM7 regulates polarized cell movements","volume":"434","author":"Su","year":"2011","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamcr.2016.05.003_bb0230","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1016\/j.ydbio.2010.11.034","article-title":"TRPM7 regulates gastrulation during vertebrate embryogenesis","volume":"350","author":"Liu","year":"2011","journal-title":"Dev. Biol."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488916301318?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488916301318?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,26]],"date-time":"2022-06-26T07:23:21Z","timestamp":1656228201000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488916301318"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":46,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2016,8]]}},"alternative-id":["S0167488916301318"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2016.05.003","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Altered expression of Mg2+ transport proteins during Parkinson's disease-like dopaminergic cell degeneration in PC12 cells","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2016.05.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V.","name":"copyright","label":"Copyright"}]}}