{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T03:41:49Z","timestamp":1789443709598,"version":"build-2803163510"},"reference-count":34,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,4,1]],"date-time":"2017-04-01T00:00:00Z","timestamp":1491004800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"vor","delay-in-days":365,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"Federal Ministry for Education and Research","award":["eMed SYMBOL-HF"],"award-info":[{"award-number":["eMed SYMBOL-HF"]}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["FR2554-2"],"award-info":[{"award-number":["FR2554-2"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"publisher","award":["RA2717\/2-1"],"award-info":[{"award-number":["RA2717\/2-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010447","name":"DZHK","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100010447","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2017,4]]},"DOI":"10.1016\/j.bbamcr.2017.01.004","type":"journal-article","created":{"date-parts":[[2017,1,10]],"date-time":"2017-01-10T15:00:58Z","timestamp":1484060458000},"page":"634-644","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Myeloid leukemia factor-1 is a novel modulator of neonatal rat cardiomyocyte proliferation"],"prefix":"10.1016","volume":"1864","author":[{"given":"Ashraf Yusuf","family":"Rangrez","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jost","family":"Pott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annika","family":"Kluge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Frauen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Stiebeling","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Hoppe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Sossalla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norbert","family":"Frey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2630-9754","authenticated-orcid":false,"given":"Derk","family":"Frank","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamcr.2017.01.004_bb0005","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1038\/nature05824","article-title":"Universal physical responses to stretch in the living cell","volume":"447","author":"Trepat","year":"2007","journal-title":"Nature"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0010","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1006\/abbi.2000.1947","article-title":"Rapid effects of stretched myocardial and vascular cells on gene expression of neonatal rat cardiomyocytes with emphasis on autocrine and paracrine mechanisms","volume":"381","author":"van Wamel","year":"2000","journal-title":"Arch. Biochem. Biophys."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0015","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1007\/s004240000253","article-title":"Rapid gene transcription induced by stretch in cardiac myocytes and fibroblasts and their paracrine influence on stationary myocytes and fibroblasts","volume":"439","author":"van Wamel","year":"2000","journal-title":"Pflugers Arch."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0020","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0008-6363(00)00076-6","article-title":"Mechanical stress-induced cardiac hypertrophy: mechanisms and signal transduction pathways","volume":"47","author":"Ruwhof","year":"2000","journal-title":"Cardiovasc. Res."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0025","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1161\/CIRCRESAHA.113.302501","article-title":"Solving the cardiac hypertrophy riddle: the angiotensin II-mechanical stress connection","volume":"113","author":"Zablocki","year":"2013","journal-title":"Circ. Res."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0030","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1161\/HYPERTENSIONAHA.107.098046","article-title":"Gene expression pattern in biomechanically stretched cardiomyocytes: evidence for a stretch-specific gene program","volume":"51","author":"Frank","year":"2008","journal-title":"Hypertension"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0035","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/bit.10506","article-title":"Anisotropic stretch-induced hypertrophy in neonatal ventricular myocytes micropatterned on deformable elastomers","volume":"81","author":"Gopalan","year":"2003","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0040","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1006\/jmcc.1998.0788","article-title":"Cyclic stretch down-regulates calcium transporter gene expression in neonatal rat ventricular myocytes","volume":"30","author":"Cadre","year":"1998","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0045","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/sj.leu.2404068","article-title":"Aberrant subcellular expression of nucleophosmin and NPM-MLF1 fusion protein in acute myeloid leukaemia carrying t(3;5): a comparison with NPMc+AML","volume":"20","author":"Falini","year":"2006","journal-title":"Leukemia"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0050","doi-asserted-by":"crossref","first-page":"250","DOI":"10.4161\/trns.21490","article-title":"Myeloid leukemia factor: a return ticket from human leukemia to fly hematopoiesis","volume":"3","author":"Gobert","year":"2012","journal-title":"Transcription"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0055","doi-asserted-by":"crossref","first-page":"1757","DOI":"10.1038\/sj.leu.2401897","article-title":"Elevated MLF1 expression correlates with malignant progression from myelodysplastic syndrome","volume":"14","author":"Matsumoto","year":"2000","journal-title":"Leukemia"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0060","first-page":"265","article-title":"The t(3;5)(q25.1;q34) of myelodysplastic syndrome and acute myeloid leukemia produces a novel fusion gene, NPM-MLF1","volume":"12","author":"Yoneda-Kato","year":"1996","journal-title":"Oncogene"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0065","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0002-9440(10)65098-5","article-title":"cDNA cloning, expression pattern, and chromosomal localization of Mlf1, murine homologue of a gene involved in myelodysplasia and acute myeloid leukemia","volume":"155","author":"Hitzler","year":"1999","journal-title":"Am. J. Pathol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0070","doi-asserted-by":"crossref","first-page":"3716","DOI":"10.1038\/sj.onc.1202711","article-title":"Apoptosis induced by the myelodysplastic syndrome-associated NPM-MLF1 chimeric protein","volume":"18","author":"Yoneda-Kato","year":"1999","journal-title":"Oncogene"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0075","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s13105-015-0445-5","article-title":"Myeloid leukemia factor 1 interfered with Bcl-XL to promote apoptosis and its function was regulated by 14-3-3","volume":"71","author":"Sun","year":"2015","journal-title":"J. Physiol. Biochem."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0080","doi-asserted-by":"crossref","first-page":"4986","DOI":"10.1073\/pnas.1117317109","article-title":"Myeloid leukemia factor is a conserved regulator of RUNX transcription factor activity involved in hematopoiesis","volume":"109","author":"Bras","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0085","doi-asserted-by":"crossref","first-page":"5105","DOI":"10.1038\/sj.onc.1207661","article-title":"Myeloid leukemia factor 1 inhibits erythropoietin-induced differentiation, cell cycle exit and p27Kip1 accumulation","volume":"23","author":"Winteringham","year":"2004","journal-title":"Oncogene"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0090","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1128\/MCB.02335-06","article-title":"Shuttling imbalance of MLF1 results in p53 instability and increases susceptibility to oncogenic transformation","volume":"28","author":"Yoneda-Kato","year":"2008","journal-title":"Mol. Cell. Biol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0095","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1038\/sj.emboj.7600656","article-title":"Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3","volume":"24","author":"Yoneda-Kato","year":"2005","journal-title":"EMBO J."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0100","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1152\/physrev.00032.2006","article-title":"Cardiac myocyte cell cycle control in development, disease, and regeneration","volume":"87","author":"Ahuja","year":"2007","journal-title":"Physiol. Rev."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0105","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.1006\/jmcc.1996.0163","article-title":"Rapid transition of cardiac myocytes from hyperplasia to hypertrophy during postnatal development","volume":"28","author":"Li","year":"1996","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0110","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.pbiomolbio.2010.11.010","article-title":"Regulation of the cardiomyocyte population in the developing heart","volume":"106","author":"Thornburg","year":"2011","journal-title":"Prog. Biophys. Mol. Biol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0115","first-page":"42","article-title":"Clinicopathologic manifestations and breakpoints of the t(3;5) in patients with acute nonlymphocytic leukemia","volume":"3","author":"Raimondi","year":"1989","journal-title":"Leukemia"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0120","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.jns.2007.07.027","article-title":"Non-pathogenic protein aggregates in skeletal muscle in MLF1 transgenic mice","volume":"264","author":"Li","year":"2008","journal-title":"J. Neurol. Sci."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0125","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1093\/hmg\/11.21.2657","article-title":"Suppression of polyglutamine toxicity by a drosophila homolog of myeloid leukemia factor 1","volume":"11","author":"Kazemi-Esfarjani","year":"2002","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0130","doi-asserted-by":"crossref","first-page":"H1829","DOI":"10.1152\/ajpheart.00205.2006","article-title":"Engineered early embryonic cardiac tissue retains proliferative and contractile properties of developing embryonic myocardium","volume":"291","author":"Tobita","year":"2006","journal-title":"Am. J. Physiol. Heart Circ. Physiol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0135","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1089\/ten.tea.2008.0169","article-title":"Engineered early embryonic cardiac tissue increases cardiomyocyte proliferation by cyclic mechanical stretch via p38-MAP kinase phosphorylation","volume":"15","author":"Clause","year":"2009","journal-title":"Tissue Eng. Part A"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0140","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.yjmcc.2014.11.003","article-title":"Cyclic stretch of embryonic cardiomyocytes increases proliferation, growth, and expression while repressing Tgf-beta signaling","volume":"79","author":"Banerjee","year":"2015","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0028890","article-title":"The effects of mechanical stress on the growth, differentiation, and paracrine factor production of cardiac stem cells","volume":"6","author":"Kurazumi","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0150","doi-asserted-by":"crossref","first-page":"17320","DOI":"10.1074\/jbc.M109.006759","article-title":"DYRK1A is a novel negative regulator of cardiomyocyte hypertrophy","volume":"284","author":"Kuhn","year":"2009","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0155","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1083\/jcb.201303052","article-title":"Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy","volume":"203","author":"Rangrez","year":"2013","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0160","doi-asserted-by":"crossref","first-page":"4128","DOI":"10.1074\/jbc.M115.689620","article-title":"Myozap deficiency promotes adverse cardiac remodeling via differential regulation of mitogen-activated protein kinase\/serum-response factor and beta-catenin\/GSK-3beta protein signaling","volume":"291","author":"Rangrez","year":"2016","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0165","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.yjmcc.2014.03.016","article-title":"Mice with cardiac-restricted overexpression of myozap are sensitized to biomechanical stress and develop a protein-aggregate-associated cardiomyopathy","volume":"72","author":"Frank","year":"2014","journal-title":"J. Mol. Cell. Cardiol."},{"key":"10.1016\/j.bbamcr.2017.01.004_bb0170","doi-asserted-by":"crossref","first-page":"10002","DOI":"10.1074\/jbc.275.14.10002","article-title":"Ischemia-induced STAT-1 expression and activation play a critical role in cardiomyocyte apoptosis","volume":"275","author":"Stephanou","year":"2000","journal-title":"J. Biol. Chem."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016748891730006X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S016748891730006X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,5]],"date-time":"2018-09-05T01:22:13Z","timestamp":1536110533000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S016748891730006X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":34,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,4]]}},"alternative-id":["S016748891730006X"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2017.01.004","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2017,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Myeloid leukemia factor-1 is a novel modulator of neonatal rat cardiomyocyte proliferation","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2017.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier B.V.","name":"copyright","label":"Copyright"}]}}