{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T00:56:44Z","timestamp":1791766604062,"version":"4.3.4"},"reference-count":59,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,8,1]],"date-time":"2023-08-01T00:00:00Z","timestamp":1690848000000},"content-version":"vor","delay-in-days":365,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31600757"],"award-info":[{"award-number":["31600757"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81570956"],"award-info":[{"award-number":["81570956"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81870744"],"award-info":[{"award-number":["81870744"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82170930"],"award-info":[{"award-number":["82170930"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.bbamcr.2022.119265","type":"journal-article","created":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T19:34:20Z","timestamp":1648928060000},"page":"119265","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":22,"title":["DDIT3\/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPK\u03b1-SIRT1 pathway"],"prefix":"10.1016","volume":"1869","author":[{"given":"Xijie","family":"Yu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoxiao","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Dong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxi","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanru","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"73","key":"10.1016\/j.bbamcr.2022.119265_bb0005","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1007\/s00018-016-2178-1","article-title":"The unfolded protein response in skeletal development and homeostasis","volume":"15","author":"Horiuchi","year":"2016","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0010","first-page":"9","article-title":"New developments in chondrocyte ER stress and related diseases","author":"Briggs","year":"2020","journal-title":"F1000Res."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0015","doi-asserted-by":"crossref","first-page":"8421394","DOI":"10.1155\/2018\/8421394","article-title":"Different forms of ER stress in chondrocytes result in short stature disorders and degenerative cartilage diseases: new insights by cartilage-specific ERp57 knockout mice","volume":"2018","author":"Rellmann","year":"2018","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"142","key":"10.1016\/j.bbamcr.2022.119265_bb0020","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1242\/dev.105536","article-title":"A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturation","volume":"5","author":"Kozhemyakina","year":"2015","journal-title":"Development"},{"issue":"28","key":"10.1016\/j.bbamcr.2022.119265_bb0025","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1002\/jbmr.1835","article-title":"Increased mandibular condylar growth in mice with estrogen receptor beta deficiency","volume":"5","author":"Kamiya","year":"2013","journal-title":"J. Bone Miner. Res."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0030","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/bs.ctdb.2015.07.008","article-title":"Genetic influences on temporomandibular joint development and growth","volume":"115","author":"Hinton","year":"2015","journal-title":"Curr. Top. Dev. Biol."},{"issue":"359","key":"10.1016\/j.bbamcr.2022.119265_bb0035","doi-asserted-by":"crossref","first-page":"2693","DOI":"10.1056\/NEJMra0802472","article-title":"Temporomandibular disorders","volume":"25","author":"Scrivani","year":"2008","journal-title":"N. Engl. J. Med."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0040","article-title":"Regulating fibrocartilage stem cells via TNF-\u03b1\/Nf-\u03baB in TMJ osteoarthritis","author":"Bi","year":"2021","journal-title":"J. Dent. Res."},{"issue":"16","key":"10.1016\/j.bbamcr.2022.119265_bb0045","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1080\/15548627.2019.1606647","article-title":"MTORC1 coordinates the autophagy and apoptosis signaling in articular chondrocytes in osteoarthritic temporomandibular joint","volume":"2","author":"Yang","year":"2020","journal-title":"Autophagy"},{"issue":"95","key":"10.1016\/j.bbamcr.2022.119265_bb0050","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1177\/0022034516640206","article-title":"Ca2+-dependent endoplasmic reticulum stress regulates mechanical stress-mediated cartilage thinning","volume":"8","author":"Zhu","year":"2016","journal-title":"J. Dent. Res."},{"issue":"49","key":"10.1016\/j.bbamcr.2022.119265_bb0055","doi-asserted-by":"crossref","first-page":"8113","DOI":"10.1039\/D0CS00259C","article-title":"Endoplasmic reticulum stress: an arising target for metal-based anticancer agents","volume":"22","author":"King","year":"2020","journal-title":"Chem. Soc. Rev."},{"issue":"11","key":"10.1016\/j.bbamcr.2022.119265_bb0060","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/sj.cdd.4401373","article-title":"Roles of CHOP\/GADD153 in endoplasmic reticulum stress","volume":"4","author":"Oyadomari","year":"2004","journal-title":"Cell Death Differ."},{"issue":"85","key":"10.1016\/j.bbamcr.2022.119265_bb0065","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1002\/jnr.21292","article-title":"Brain-derived neurotrophic factor suppresses tunicamycin-induced upregulation of CHOP in neurons","volume":"8","author":"Chen","year":"2007","journal-title":"J. Neurosci. Res."},{"issue":"92","key":"10.1016\/j.bbamcr.2022.119265_bb0070","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1111\/j.1365-2613.2010.00758.x","article-title":"Enhanced apoptotic and reduced protective response in chondrocytes following endoplasmic reticulum stress in osteoarthritic cartilage","volume":"4","author":"Takada","year":"2011","journal-title":"Int. J. Exp. Pathol."},{"issue":"345","key":"10.1016\/j.bbamcr.2022.119265_bb0075","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1126\/science.1254312","article-title":"Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis","volume":"6192","author":"Lu","year":"2014","journal-title":"Science"},{"issue":"485","key":"10.1016\/j.bbamcr.2022.119265_bb0080","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1038\/nature11058","article-title":"Sustained translational repression by eIF2\u03b1-P mediates prion neurodegeneration","volume":"7399","author":"Moreno","year":"2012","journal-title":"Nature"},{"issue":"283","key":"10.1016\/j.bbamcr.2022.119265_bb0085","doi-asserted-by":"crossref","first-page":"17020","DOI":"10.1074\/jbc.M802466200","article-title":"Endoplasmic reticulum (ER) chaperone regulation and survival of cells compensating for deficiency in the ER stress response kinase,PERK","volume":"25","author":"Yamaguchi","year":"2008","journal-title":"J. Biol. Chem."},{"issue":"278","key":"10.1016\/j.bbamcr.2022.119265_bb0090","doi-asserted-by":"crossref","first-page":"37375","DOI":"10.1074\/jbc.M303619200","article-title":"Induction of Grp78\/BiP by translational block: activation of the Grp78 promoter by ATF4 through and upstream ATF\/CRE site independent of the endoplasmic reticulum stress elements","volume":"39","author":"Luo","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0095","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.37673","article-title":"Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia","volume":"7","author":"Wang","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.bbamcr.2022.119265_bb0100","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.biocel.2016.11.009","article-title":"Ddit3 suppresses the differentiation of mouse chondroprogenitor cells","volume":"81","author":"Yu","year":"2016","journal-title":"<sb:contribution><sb:title>Int. J. Biochem. Cell Biol.<\/sb:title><\/sb:contribution><sb:host><sb:issue><sb:series><sb:title> A<\/sb:title><\/sb:series><\/sb:issue><\/sb:host>"},{"key":"10.1016\/j.bbamcr.2022.119265_bb0105","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.freeradbiomed.2018.08.001","article-title":"Mechanical stretch induces antioxidant responses and osteogenic differentiation in human mesenchymal stem cells through activation of the AMPK-SIRT1 signaling pathway","volume":"126","author":"Chen","year":"2018","journal-title":"Free Radic. Biol. Med."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0110","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.bone.2014.12.001","article-title":"AMP-activated protein kinase (AMPK) activity negatively regulates chondrogenic differentiation","volume":"74","author":"Bandow","year":"2015","journal-title":"Bone"},{"key":"10.1016\/j.bbamcr.2022.119265_bb0115","doi-asserted-by":"crossref","first-page":"7543973","DOI":"10.1155\/2017\/7543973","article-title":"Sirt1 inhibits oxidative stress in vascular endothelial cells","volume":"2017","author":"Zhang","year":"2017","journal-title":"Oxidative Med. Cell. Longev."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.lfs.2021.119041","article-title":"SIRT1, a promising regulator of bone homeostasis","volume":"269","author":"Chen","year":"2021","journal-title":"Life Sci."},{"issue":"1868","key":"10.1016\/j.bbamcr.2022.119265_bb0125","article-title":"AMPK\/SIRT1 signaling through p38MAPK mediates Interleukin-6 induced neuroendocrine differentiation of LNCaP prostate cancer cells","volume":"10","author":"Natani","year":"2021","journal-title":"Biochim. Biophys. Acta Mol.Cell Res."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0130","article-title":"DDIT3\/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway","volume":"9","author":"Yang","year":"2021","journal-title":"Biochim. Biophys. Acta Mol.Cell Res."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0135","first-page":"20","article-title":"Inhibition of Ihh reverses temporomandibular joint osteoarthritis via a PTH1R signaling dependent mechanism","volume":"15","author":"Yang","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.bbamcr.2022.119265_bb0140","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1002\/jor.1100100107","article-title":"The reliability of the Mankin score for osteoarthritis","volume":"1","author":"van der Sluijs","year":"1992","journal-title":"J. Orthop. Res."},{"issue":"30","key":"10.1016\/j.bbamcr.2022.119265_bb0145","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/0922-3371(90)90079-C","article-title":"A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells","volume":"2","author":"Atsumi","year":"1990","journal-title":"Cell Differ. Dev."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111058","article-title":"Involvement of Bmal1 and circadian clock signaling in chondrogenic differentiation of ATDC5 cells by fluoride","volume":"204","author":"Li","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"issue":"114","key":"10.1016\/j.bbamcr.2022.119265_bb0155","doi-asserted-by":"crossref","first-page":"1223","DOI":"10.1002\/jcb.24467","article-title":"ATDC5: an excellent in vitro model cell line for skeletal development","volume":"6","author":"Yao","year":"2013","journal-title":"J. Cell. Biochem."},{"issue":"286","key":"10.1016\/j.bbamcr.2022.119265_bb0160","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/febs.14608","article-title":"Endoplasmic reticulum stress signalling - from basic mechanisms to clinical applications","volume":"2","author":"Almanza","year":"2019","journal-title":"FEBS J."},{"issue":"288","key":"10.1016\/j.bbamcr.2022.119265_bb0165","doi-asserted-by":"crossref","first-page":"18172","DOI":"10.1074\/jbc.M112.407296","article-title":"Endoplasmic reticulum stress regulates rat mandibular cartilage thinning under compressive mechanical stress","volume":"25","author":"Li","year":"2013","journal-title":"J. Biol. Chem."},{"issue":"47","key":"10.1016\/j.bbamcr.2022.119265_bb0170","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/jop.12715","article-title":"Expression of endoplasmic reticulum stress protein in rabbit condyle cartilage following anterior disk displacement","volume":"6","author":"Xu","year":"2018","journal-title":"J. Oral Pathol. Med."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0175","article-title":"Lumenal Galectin-9-Lamp2 interaction regulates lysosome and autophagy to prevent pathogenesis in the intestine and pancreas","volume":"1","author":"Sudhakar","year":"2020","journal-title":"Nat. Commun."},{"issue":"25","key":"10.1016\/j.bbamcr.2022.119265_bb0180","doi-asserted-by":"crossref","first-page":"1375","DOI":"10.1038\/s41418-017-0044-9","article-title":"eIF2\u03b1 phosphorylation is pathognomonic for immunogenic cell death","volume":"8","author":"Bezu","year":"2018","journal-title":"Cell Death Differ."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0185","first-page":"578","article-title":"Involvement of ER stress in retinal cell death","volume":"13","author":"Shimazawa","year":"2007","journal-title":"Mol. Vis."},{"issue":"7","key":"10.1016\/j.bbamcr.2022.119265_bb0190","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1038\/nrd2755","article-title":"Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities","volume":"12","author":"Kim","year":"2008","journal-title":"Nat. Rev. Drug Discov."},{"issue":"234","key":"10.1016\/j.bbamcr.2022.119265_bb0195","doi-asserted-by":"crossref","first-page":"11602","DOI":"10.1002\/jcp.27811","article-title":"DDIT3 regulates cementoblast mineralization by isocitrate dehydrogenase 1 through nuclear factor-\u03baB pathway","volume":"7","author":"Liu","year":"2019","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0200","first-page":"8","article-title":"Osteochondritis dissecans (OCD)-derived chondrocytes display increased senescence, oxidative stress, chaperone-mediated autophagy and, in co-culture with adipose-derived stem cells (ASCs), enhanced expression of MMP-13","volume":"3","author":"Kornicka","year":"2019","journal-title":"J. Clin. Med."},{"issue":"180","key":"10.1016\/j.bbamcr.2022.119265_bb0205","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.ajpath.2011.10.035","article-title":"Chop (Ddit3) is essential for D469del-COMP retention and cell death in chondrocytes in an inducible transgenic mouse model of pseudoachondroplasia","volume":"2","author":"Posey","year":"2012","journal-title":"Am. J. Pathol."},{"issue":"22","key":"10.1016\/j.bbamcr.2022.119265_bb0210","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/j.joca.2014.04.025","article-title":"Endoplasmic reticulum stress-induced apoptosis contributes to articular cartilage degeneration via C\/EBP homologous protein","volume":"7","author":"Uehara","year":"2014","journal-title":"Osteoarthr. Cartil."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0215","doi-asserted-by":"crossref","first-page":"8574386","DOI":"10.1155\/2019\/8574386","article-title":"Curcumin inhibits the PERK-eIF2\u03b1-CHOP pathway through promoting SIRT1 expression in oxidative stress-induced rat chondrocytes and ameliorates osteoarthritis progression in a rat model","volume":"2019","author":"Feng","year":"2019","journal-title":"Oxidative Med. Cell. Longev."},{"issue":"365","key":"10.1016\/j.bbamcr.2022.119265_bb0220","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.canlet.2015.05.027","article-title":"IDH1, a CHOP and C\/EBP\u03b2-responsive gene under ER stress, sensitizes human melanoma cells to hypoxia-induced apoptosis","volume":"2","author":"Yang","year":"2015","journal-title":"Cancer Lett."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0225","article-title":"The role of sirtuin 1 and its activator, resveratrol in osteoarthritis","volume":"5","author":"Deng","year":"2019","journal-title":"Biosci. Rep."},{"issue":"280","key":"10.1016\/j.bbamcr.2022.119265_bb0230","doi-asserted-by":"crossref","first-page":"17038","DOI":"10.1074\/jbc.M500655200","article-title":"Substrate-specific activation of sirtuins by resveratrol","volume":"17","author":"Kaeberlein","year":"2005","journal-title":"J. Biol. Chem."},{"issue":"23","key":"10.1016\/j.bbamcr.2022.119265_bb0235","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.jnutbio.2011.09.010","article-title":"MicroRNAs in the growth plate are responsive to nutritional cues: association between miR-140 and SIRT1","volume":"11","author":"Pando","year":"2012","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0240","doi-asserted-by":"crossref","DOI":"10.1016\/j.bone.2020.115468","article-title":"Cartilage-specific knockout of Sirt1 significantly reduces bone quality and catch-up growth efficiency","volume":"138","author":"Shtaif","year":"2020","journal-title":"Bone"},{"issue":"289","key":"10.1016\/j.bbamcr.2022.119265_bb0245","doi-asserted-by":"crossref","first-page":"22048","DOI":"10.1074\/jbc.M114.568790","article-title":"Sirtuin-1 (SIRT1) is required for promoting chondrogenic differentiation of mesenchymal stem cells","volume":"32","author":"Buhrmann","year":"2014","journal-title":"J. Biol. Chem."},{"issue":"293","key":"10.1016\/j.bbamcr.2022.119265_bb0250","doi-asserted-by":"crossref","first-page":"8614","DOI":"10.1074\/jbc.M117.809822","article-title":"Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK-eIF-2\u03b1-CHOP pathway in the unfolded protein response","volume":"22","author":"Kang","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamcr.2022.119265_bb0255","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1038\/s41420-020-0277-0","article-title":"SIRT1 directly activates autophagy in human chondrocytes","volume":"6","author":"Sacitharan","year":"2020","journal-title":"Cell Death Discov."},{"issue":"232","key":"10.1016\/j.bbamcr.2022.119265_bb0260","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1002\/jcp.25785","article-title":"Crosstalk of autophagy and apoptosis: involvement of the dual role of autophagy under ER stress","volume":"11","author":"Song","year":"2017","journal-title":"J. Cell. Physiol."},{"issue":"26","key":"10.1016\/j.bbamcr.2022.119265_bb0265","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/j.cellsig.2013.10.004","article-title":"Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3","volume":"2","author":"Rubiolo","year":"2014","journal-title":"Cell. Signal."},{"issue":"282","key":"10.1016\/j.bbamcr.2022.119265_bb0270","doi-asserted-by":"crossref","first-page":"4702","DOI":"10.1074\/jbc.M609267200","article-title":"Differential effects of endoplasmic reticulum stress-induced autophagy on cell survival","volume":"7","author":"Ding","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"11","key":"10.1016\/j.bbamcr.2022.119265_bb0275","doi-asserted-by":"crossref","first-page":"1956","DOI":"10.1080\/15548627.2015.1091141","article-title":"ER stress: autophagy induction, inhibition and selection","volume":"11","author":"Rashid","year":"2015","journal-title":"Autophagy"},{"key":"10.1016\/j.bbamcr.2022.119265_bb0280","article-title":"L-arginine protects cementoblasts against hypoxia-induced apoptosis through Sirt1-enhanced autophagy","author":"Xu","year":"2021","journal-title":"J. Periodontol."},{"issue":"17","key":"10.1016\/j.bbamcr.2022.119265_bb0285","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/15548627.2020.1797280","article-title":"Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1)","volume":"1","author":"Klionsky","year":"2021","journal-title":"Autophagy"},{"issue":"2","key":"10.1016\/j.bbamcr.2022.119265_bb0290","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1158\/2159-8290.CD-11-0280","article-title":"Metformin accelerates the growth of BRAF V600E-driven melanoma by upregulating VEGF-A","volume":"4","author":"Martin","year":"2012","journal-title":"Cancer Discov."},{"issue":"1","key":"10.1016\/j.bbamcr.2022.119265_bb0295","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1504\/IJCIH.2012.046995","article-title":"A cell-matrix model of anabolic and catabolic dynamics during cartilage biomolecule regulation","volume":"3","author":"Saha","year":"2012","journal-title":"Int. J. Comput. Healthc."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488922000568?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488922000568?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T19:58:52Z","timestamp":1759089532000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488922000568"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":59,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S0167488922000568"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2022.119265","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"DDIT3\/CHOP mediates the inhibitory effect of ER stress on chondrocyte differentiation by AMPK\u03b1-SIRT1 pathway","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2022.119265","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"119265"}}