{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T21:14:48Z","timestamp":1788470088171,"version":"build-2803163510"},"reference-count":61,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"vor","delay-in-days":366,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.bbamcr.2023.119525","type":"journal-article","created":{"date-parts":[[2023,6,20]],"date-time":"2023-06-20T06:08:20Z","timestamp":1687241300000},"page":"119525","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"title":["NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis"],"prefix":"10.1016","volume":"1870","author":[{"given":"Youhua","family":"Peng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meijunzi","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-ning","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingting","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feifei","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biying","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chongjun","family":"Ran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haizhen","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0005","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1016\/j.clindermatol.2007.08.013","article-title":"Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes","volume":"25","author":"Albanesi","year":"2007","journal-title":"Clin. Dermatol."},{"issue":"20","key":"10.1016\/j.bbamcr.2023.119525_bb0010","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21207488","article-title":"New treatment addressing the pathogenesis of psoriasis","volume":"21","author":"Tokuyama","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0015","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.autrev.2013.11.008","article-title":"Interleukin-22: a likely target for treatment of autoimmune diseases","volume":"13","author":"Yang","year":"2014","journal-title":"Autoimmun. Rev."},{"issue":"7128","key":"10.1016\/j.bbamcr.2023.119525_bb0020","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1038\/nature05505","article-title":"Interleukin-22, a T(H)17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis","volume":"445","author":"Zheng","year":"2007","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0025","doi-asserted-by":"crossref","first-page":"3695","DOI":"10.4049\/jimmunol.174.6.3695","article-title":"IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes","volume":"174","author":"Boniface","year":"2005","journal-title":"J. Immunol."},{"issue":"9","key":"10.1016\/j.bbamcr.2023.119525_bb0030","doi-asserted-by":"crossref","first-page":"933","DOI":"10.2174\/1381612003400182","article-title":"Inhibitors of tyrosine kinases in the treatment of psoriasis","volume":"6","author":"Ben-Bassat","year":"2000","journal-title":"Curr. Pharm. Des."},{"issue":"14","key":"10.1016\/j.bbamcr.2023.119525_bb0035","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1056\/NEJMoa1806382","article-title":"Phase 2 trial of selective tyrosine kinase 2 inhibition in psoriasis","volume":"379","author":"Papp","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.bbamcr.2023.119525_bb0040","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1007\/s40265-020-01261-8","article-title":"JAK inhibitors for treatment of psoriasis: focus on selective TYK2 inhibitors","volume":"80","author":"Nogueira","year":"2020","journal-title":"Drugs"},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0045","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1053\/j.gastro.2020.01.001","article-title":"Safety of Janus kinase inhibitors in patients with inflammatory bowel diseases or other immune-mediated diseases: a systematic review and meta-analysis","volume":"158","author":"Olivera","year":"2020","journal-title":"Gastroenterology"},{"issue":"12","key":"10.1016\/j.bbamcr.2023.119525_bb0050","doi-asserted-by":"crossref","first-page":"843","DOI":"10.1038\/nrd.2017.201","article-title":"JAK inhibition as a therapeutic strategy for immune and inflammatory diseases","volume":"16","author":"Schwartz","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0055","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.3389\/fimmu.2019.02847","article-title":"Emerging topical and systemic JAK inhibitors in dermatology","volume":"10","author":"Solimani","year":"2019","journal-title":"Front. Immunol."},{"issue":"5","key":"10.1016\/j.bbamcr.2023.119525_bb0060","doi-asserted-by":"crossref","first-page":"357","DOI":"10.3109\/00498251003663724","article-title":"Baicalin, an emerging multi-therapeutic agent: pharmacodynamics, pharmacokinetics, and considerations from drug development perspectives","volume":"40","author":"Srinivas","year":"2010","journal-title":"Xenobiotica"},{"issue":"8","key":"10.1016\/j.bbamcr.2023.119525_bb0065","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1002\/bdd.771","article-title":"Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones","volume":"32","author":"Li","year":"2011","journal-title":"Biopharm. Drug Dispos."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0070","doi-asserted-by":"crossref","DOI":"10.12659\/MSM.919392","article-title":"Baicalin inhibits cell proliferation and inflammatory cytokines induced by tumor necrosis factor alpha (TNF-alpha) in human immortalized keratinocytes (HaCaT) human keratinocytes by inhibiting the STAT3\/nuclear factor kappa B (NF-kappaB) signaling pathway","volume":"26","author":"Wu","year":"2020","journal-title":"Med. Sci. Monit."},{"issue":"5","key":"10.1016\/j.bbamcr.2023.119525_bb0075","first-page":"441","article-title":"Baicalin inhibits the activity of keratinocytes in psoriasis by activating Notch signaling pathway","volume":"35","author":"Wang","year":"2019","journal-title":"Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi"},{"issue":"15","key":"10.1016\/j.bbamcr.2023.119525_bb0080","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1055\/a-0622-8242","article-title":"Baicalin ameliorates Imiquimod-induced psoriasis-like inflammation in mice","volume":"84","author":"Hung","year":"2018","journal-title":"Planta Med."},{"issue":"3 Pt B","key":"10.1016\/j.bbamcr.2023.119525_bb0085","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/j.jid.2021.06.019","article-title":"Mouse models of psoriasis: a comprehensive review","volume":"142","author":"Gangwar","year":"2022","journal-title":"The Journal of Investigative Dermatology"},{"issue":"12","key":"10.1016\/j.bbamcr.2023.119525_bb0090","doi-asserted-by":"crossref","DOI":"10.3390\/ijms18122514","article-title":"Models in the research process of psoriasis","volume":"18","author":"Boche\u0144ska","year":"2017","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.bbamcr.2023.119525_bb0095","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/1346-8138.14112","article-title":"Mouse models of psoriasis and their relevance","volume":"45","author":"Nakajima","year":"2018","journal-title":"J. Dermatol."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.ebiom.2020.102876","article-title":"Hyperlipidaemia and IFNgamma\/TNFalpha synergism are associated with cholesterol crystal formation in endothelial cells partly through modulation of lysosomal pH and cholesterol homeostasis","volume":"59","author":"Baumer","year":"2020","journal-title":"EBioMedicine"},{"key":"10.1016\/j.bbamcr.2023.119525_bb0105","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.diff.2017.09.004","article-title":"Human reconstructed skin xenografts on mice to model skin physiology","volume":"98","author":"Salgado","year":"2017","journal-title":"Differentiation; Research In Biological Diversity"},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0110","doi-asserted-by":"crossref","DOI":"10.1172\/JCI130740","article-title":"Galectin-7 downregulation in lesional keratinocytes contributes to enhanced IL-17A signaling and skin pathology in psoriasis","volume":"131","author":"Chen","year":"2021","journal-title":"J. Clin. Invest."},{"issue":"9","key":"10.1016\/j.bbamcr.2023.119525_bb0115","doi-asserted-by":"crossref","first-page":"5836","DOI":"10.4049\/jimmunol.0802999","article-title":"Imiquimod-induced psoriasis-like skin inflammation in mice is mediated via the IL-23\/IL-17 axis","volume":"182","author":"van der Fits","year":"2009","journal-title":"J. Immunol."},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0120","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s12865-021-00401-3","article-title":"Application of imiquimod-induced murine psoriasis model in evaluating interleukin-17A antagonist","volume":"22","author":"Li","year":"2021","journal-title":"BMC Immunol."},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0125","article-title":"Downregulation of TNIP1 expression leads to increased proliferation of human keratinocytes and severer psoriasis-like conditions in an Imiquimod-induced mouse model of dermatitis","volume":"10","author":"Chen","year":"2015","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0130","doi-asserted-by":"crossref","DOI":"10.1042\/BSR20180958","article-title":"Indirubin attenuates mouse psoriasis-like skin lesion in a CD274-dependent manner: an achievement of RNA sequencing","volume":"38","author":"Xue","year":"2018","journal-title":"Biosci. Rep."},{"issue":"7","key":"10.1016\/j.bbamcr.2023.119525_bb0135","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0002737","article-title":"Type I interferon: potential therapeutic target for psoriasis?","volume":"3","author":"Yao","year":"2008","journal-title":"PLoS One"},{"issue":"2","key":"10.1016\/j.bbamcr.2023.119525_bb0140","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1038\/ng.311","article-title":"Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways","volume":"41","author":"Nair","year":"2009","journal-title":"Nat. Genet."},{"issue":"8","key":"10.1016\/j.bbamcr.2023.119525_bb0145","doi-asserted-by":"crossref","first-page":"3828","DOI":"10.4049\/jimmunol.1301737","article-title":"Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody","volume":"192","author":"Russell","year":"2014","journal-title":"J. Immunol."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0150","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1016\/j.lfs.2019.01.019","article-title":"Hesperidin inhibits keratinocyte proliferation and imiquimod-induced psoriasis-like dermatitis via the IRS-1\/ERK1\/2 pathway","volume":"219","author":"Li","year":"2019","journal-title":"Life Sci."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0155","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2022.712313","article-title":"Novel therapeutic target(s) for psoriatic disease","volume":"9","author":"Thakur","year":"2022","journal-title":"Frontiers In Medicine"},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0160","doi-asserted-by":"crossref","DOI":"10.3390\/ijms19010171","article-title":"Psoriasis: a STAT3-centric view","volume":"19","author":"Calautti","year":"2018","journal-title":"Int. J. Mol. Sci."},{"issue":"10","key":"10.1016\/j.bbamcr.2023.119525_bb0165","article-title":"STAT3 activation in psoriasis and cancers","volume":"11","author":"Kishimoto","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"20","key":"10.1016\/j.bbamcr.2023.119525_bb0170","first-page":"5330","article-title":"Exploration of active components and mechanism of Scutellariae Radix-Phellodendri Chinensis Cortex drug pair in treatment of psoriasis based on network pharmacology and molecular docking","volume":"46","author":"Ma","year":"2021","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"issue":"2","key":"10.1016\/j.bbamcr.2023.119525_bb0175","first-page":"2128","article-title":"Effects of baicalin cream in two mouse models: 2,4-dinitrofluorobenzene-induced contact hypersensitivity and mouse tail test for psoriasis","volume":"8","author":"Wu","year":"2015","journal-title":"Int. J. Clin. Exp. Med."},{"key":"10.1016\/j.bbamcr.2023.119525_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.tox.2021.152840","article-title":"Hepatotoxic potentials of methotrexate: understanding the possible toxicological molecular mechanisms","volume":"458","author":"Ezhilarasan","year":"2021","journal-title":"Toxicology"},{"issue":"2","key":"10.1016\/j.bbamcr.2023.119525_bb0185","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1093\/emboj\/17.2.470","article-title":"A centrosomal function for the human Nek2 protein kinase, a member of the NIMA family of cell cycle regulators","volume":"17","author":"Fry","year":"1998","journal-title":"EMBO J."},{"issue":"7","key":"10.1016\/j.bbamcr.2023.119525_bb0190","doi-asserted-by":"crossref","first-page":"1648","DOI":"10.1038\/leu.2017.115","article-title":"NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma","volume":"31","author":"Hao","year":"2017","journal-title":"Leukemia"},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0195","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1083\/jcb.200504107","article-title":"Rootletin forms centriole-associated filaments and functions in centrosome cohesion","volume":"171","author":"Bahe","year":"2005","journal-title":"J. Cell Biol."},{"issue":"36","key":"10.1016\/j.bbamcr.2023.119525_bb0200","doi-asserted-by":"crossref","first-page":"26431","DOI":"10.1074\/jbc.M704969200","article-title":"Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase","volume":"282","author":"Wu","year":"2007","journal-title":"J. Biol. Chem."},{"issue":"Pt 19","key":"10.1016\/j.bbamcr.2023.119525_bb0205","first-page":"4423","article-title":"Cell cycle regulation by the NEK family of protein kinases","volume":"125","author":"Fry","year":"2012","journal-title":"J. Cell Sci."},{"issue":"3","key":"10.1016\/j.bbamcr.2023.119525_bb0210","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s10549-017-4652-3","article-title":"Functional transcriptomic annotation and protein-protein interaction network analysis identify NEK2, BIRC5, and TOP2A as potential targets in obese patients with luminal A breast cancer","volume":"168","author":"Nuncia-Cantarero","year":"2018","journal-title":"Breast Cancer Res. Treat."},{"issue":"7","key":"10.1016\/j.bbamcr.2023.119525_bb0215","doi-asserted-by":"crossref","first-page":"828","DOI":"10.1002\/jso.23717","article-title":"Overexpression of the Nek2 kinase in colorectal cancer correlates with beta-catenin relocalization and shortened cancer-specific survival","volume":"110","author":"Neal","year":"2014","journal-title":"J. Surg. Oncol."},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0220","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1186\/s13046-020-01659-y","article-title":"Targeting NEK2 impairs oncogenesis and radioresistance via inhibiting the Wnt1\/beta-catenin signaling pathway in cervical cancer","volume":"39","author":"Xu","year":"2020","journal-title":"J. Exp. Clin. Cancer Res."},{"issue":"4","key":"10.1016\/j.bbamcr.2023.119525_bb0225","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/1759-7714.12442","article-title":"MicroRNA-128 promotes apoptosis in lung cancer by directly targeting NIMA-related kinase 2","volume":"8","author":"Zhao","year":"2017","journal-title":"Thorac Cancer"},{"issue":"7","key":"10.1016\/j.bbamcr.2023.119525_bb0230","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1080\/15384101.2016.1152430","article-title":"Targeting NEK2 as a promising therapeutic approach for cancer treatment","volume":"15","author":"Fang","year":"2016","journal-title":"Cell Cycle"},{"issue":"42","key":"10.1016\/j.bbamcr.2023.119525_bb0235","doi-asserted-by":"crossref","first-page":"10666","DOI":"10.1073\/pnas.1806643115","article-title":"Literature-based automated discovery of tumor suppressor p53 phosphorylation and inhibition by NEK2","volume":"115","author":"Choi","year":"2018","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"33","key":"10.1016\/j.bbamcr.2023.119525_bb0240","doi-asserted-by":"crossref","first-page":"9304","DOI":"10.1073\/pnas.1608783113","article-title":"Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins","volume":"113","author":"Cervenka","year":"2016","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"3","key":"10.1016\/j.bbamcr.2023.119525_bb0245","first-page":"1023","article-title":"NEK2 promotes hepatocellular carcinoma migration and invasion through modulation of the epithelial-mesenchymal transition","volume":"39","author":"Zhang","year":"2018","journal-title":"Oncol. Rep."},{"issue":"1","key":"10.1016\/j.bbamcr.2023.119525_bb0250","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1038\/nrd4176","article-title":"Therapeutic opportunities of the IL-22-IL-22R1 system","volume":"13","author":"Sabat","year":"2014","journal-title":"Nat. Rev. Drug Discov."},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0255","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1016\/j.cytogfr.2010.10.007","article-title":"Distinct roles of IL-22 in human psoriasis and inflammatory bowel disease","volume":"21","author":"Ouyang","year":"2010","journal-title":"Cytokine Growth Factor Rev."},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0260","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1016\/j.immuni.2012.08.024","article-title":"Th22 cells are an important source of IL-22 for host protection against enteropathogenic bacteria","volume":"37","author":"Basu","year":"2012","journal-title":"Immunity"},{"issue":"5","key":"10.1016\/j.bbamcr.2023.119525_bb0265","first-page":"1092","article-title":"Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways","volume":"159","author":"Nograles","year":"2008","journal-title":"Br. J. Dermatol."},{"issue":"5","key":"10.1016\/j.bbamcr.2023.119525_bb0270","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1002\/eji.200535503","article-title":"IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis","volume":"36","author":"Wolk","year":"2006","journal-title":"Eur. J. Immunol."},{"issue":"5","key":"10.1016\/j.bbamcr.2023.119525_bb0275","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1007\/s00109-009-0457-0","article-title":"IL-22 and IL-20 are key mediators of the epidermal alterations in psoriasis while IL-17 and IFN-gamma are not","volume":"87","author":"Wolk","year":"2009","journal-title":"J Mol Med (Berl)"},{"issue":"223","key":"10.1016\/j.bbamcr.2023.119525_bb0280","doi-asserted-by":"crossref","first-page":"223ra22","DOI":"10.1126\/scitranslmed.3007217","article-title":"Integrative biology approach identifies cytokine targeting strategies for psoriasis","volume":"6","author":"Perera","year":"2014","journal-title":"Sci. Transl. Med."},{"issue":"11","key":"10.1016\/j.bbamcr.2023.119525_bb0285","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1038\/s41419-021-04284-5","article-title":"Inhibition of keratinocyte ferroptosis suppresses psoriatic inflammation","volume":"12","author":"Shou","year":"2021","journal-title":"Cell Death Dis."},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0290","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1177\/1203475415584503","article-title":"IL-17A, IL-22, and IL-23 as markers of psoriasis activity: a cross-sectional","volume":"19","author":"Fotiadou","year":"2015","journal-title":"Hospital-based Study. J Cutan Med Surg"},{"issue":"6","key":"10.1016\/j.bbamcr.2023.119525_bb0295","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1038\/jid.2014.81","article-title":"22 again: IL-22 as a risk gene and important mediator in psoriasis","volume":"134","author":"Johnston","year":"2014","journal-title":"J Invest Dermatol"},{"issue":"4","key":"10.1016\/j.bbamcr.2023.119525_bb0300","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1684\/ecn.2011.0294","article-title":"Cytokine network in psoriasis revisited","volume":"22","author":"Michalak-Stoma","year":"2011","journal-title":"Eur. Cytokine Netw."},{"issue":"7","key":"10.1016\/j.bbamcr.2023.119525_bb0305","article-title":"The pro-inflammatory cytokine IL-22 up-regulates keratin 17 expression in keratinocytes via STAT3 and ERK1\/2","volume":"7","author":"Zhang","year":"2012","journal-title":"PLoS One"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488923000976?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488923000976?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T17:22:28Z","timestamp":1733073748000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488923000976"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":61,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S0167488923000976"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2023.119525","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NEK2 overexpression aggravates IL-22-induced keratinocyte proliferation and cytokine level increases and IMQ-induced psoriasis-like dermatitis","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2023.119525","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"119525"}}