{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T10:20:03Z","timestamp":1783160403044,"version":"3.54.6"},"reference-count":23,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81860464"],"award-info":[{"award-number":["81860464"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007452","name":"Wu Jieping Medical Foundation","doi-asserted-by":"publisher","award":["2025-20"],"award-info":[{"award-number":["2025-20"]}],"id":[{"id":"10.13039\/100007452","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.bbamcr.2026.120162","type":"journal-article","created":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T23:34:51Z","timestamp":1779838491000},"page":"120162","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["TMEM132A affects proliferation, invasion, and apoptosis via the \u03b2-catenin-dependent Wnt signaling in breast cancer"],"prefix":"10.1016","volume":"1873","author":[{"given":"Xiaoqiang","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linmiao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huawei","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bbamcr.2026.120162_bb0005","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1038\/s41392-021-00762-6","article-title":"Wnt\/\u03b2-catenin signalling: function, biological mechanisms, and therapeutic opportunities","volume":"7","author":"Liu","year":"2022","journal-title":"Signal Transduct. Target. Ther."},{"issue":"5","key":"10.1016\/j.bbamcr.2026.120162_bb0010","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1080\/15257770.2022.2148692","article-title":"Knockdown of TMEM132A restrains the malignant phenotype of gastric cancer cells via inhibiting Wnt signaling","volume":"42","author":"Gao","year":"2023","journal-title":"Nucleosides Nucleotides Nucleic Acids"},{"issue":"4","key":"10.1016\/j.bbamcr.2026.120162_bb0015","first-page":"497","article-title":"Breast cancer in the world and China in 2022: an analysis on epidemic status","volume":"46","author":"Miao","year":"2025","journal-title":"Acad. J. Sec. Mil. Med. Univ."},{"issue":"1","key":"10.1016\/j.bbamcr.2026.120162_bb0020","doi-asserted-by":"crossref","DOI":"10.1038\/s41523-022-00468-0","article-title":"Triple negative breast cancer: pitfalls and progress","volume":"8","author":"Zagami","year":"2022","journal-title":"Npj Breast Cancer"},{"issue":"5","key":"10.1016\/j.bbamcr.2026.120162_bb0025","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a008052","article-title":"Wnt signaling in cancer","volume":"4","author":"Polakis","year":"2012","journal-title":"Cold Spring Harb. Perspect. Biol."},{"issue":"1","key":"10.1016\/j.bbamcr.2026.120162_bb0030","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.devcel.2009.06.016","article-title":"Wnt\/\u03b2-catenin signaling: components, mechanisms, and diseases","volume":"17","author":"MacDonald","year":"2009","journal-title":"Dev. Cell"},{"issue":"11","key":"10.1016\/j.bbamcr.2026.120162_bb0035","doi-asserted-by":"crossref","first-page":"1461","DOI":"10.1038\/onc.2016.304","article-title":"Wnt signaling in cancer","volume":"36","author":"Zhan","year":"2017","journal-title":"Oncogene"},{"issue":"6","key":"10.1016\/j.bbamcr.2026.120162_bb0040","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1186\/bcr2723","article-title":"Key signaling nodes in breast gland development and cancer: \u03b2-catenin","volume":"12","author":"Incassati","year":"2010","journal-title":"Breast Cancer Res."},{"key":"10.1016\/j.bbamcr.2026.120162_bb0045","doi-asserted-by":"crossref","DOI":"10.3389\/fcell.2020.599890","article-title":"TMEM132A, a novel Wnt signaling pathway regulator through Wntless (WLS) interaction","volume":"8","author":"Li","year":"2020","journal-title":"Frontiers in Cell and Developmental Biology"},{"key":"10.1016\/j.bbamcr.2026.120162_bb0050","first-page":"1386","article-title":"Wnt\/\u03b2-catenin signalling: function, biological mechanisms, and therapeutic opportunities","author":"Li","year":"2022","journal-title":"Chinese Bulletin of Life Sciences"},{"issue":"8","key":"10.1016\/j.bbamcr.2026.120162_bb0055","doi-asserted-by":"crossref","DOI":"10.3390\/cells8080826","article-title":"WNT signaling in disease","volume":"8","author":"Ng","year":"2019","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.bbamcr.2026.120162_bb0060","doi-asserted-by":"crossref","DOI":"10.1186\/s12964-024-01855-9","article-title":"TMEM132A regulates Wnt\/\u03b2-catenin signaling through stabilizing LRP6 during mouse embryonic development","volume":"22","author":"Oh","year":"2024","journal-title":"Cell Commun. Signal."},{"issue":"1","key":"10.1016\/j.bbamcr.2026.120162_bb0065","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/apm.13194","article-title":"Silencing KLF16 inhibits oral squamous cell carcinoma cell proliferation by arresting the cell cycle and inducing apoptosis","volume":"130","author":"Yang","year":"2022","journal-title":"APMIS"},{"issue":"16","key":"10.1016\/j.bbamcr.2026.120162_bb0070","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1038\/s41388-022-02247-4","article-title":"RNF4 silencing induces cell growth arrest and DNA damage by promoting nuclear targeting of p62 in hepatocellular carcinoma","volume":"41","author":"Lv","year":"2022","journal-title":"Oncogene"},{"issue":"14","key":"10.1016\/j.bbamcr.2026.120162_bb0075","doi-asserted-by":"crossref","DOI":"10.3390\/cancers13143410","article-title":"Hedgehog\/GLI signaling pathway: transduction, regulation, and implications for disease","volume":"13","author":"Sigafoos","year":"2021","journal-title":"Cancers"},{"issue":"6","key":"10.1016\/j.bbamcr.2026.120162_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3892\/ijo.2025.5755","article-title":"Targeting CALR reduces energy metabolism of esophageal cancer cells and inhibits tumor-associated fibroblast infiltration","volume":"66","author":"Miao","year":"2025","journal-title":"Int. J. Oncol."},{"issue":"8","key":"10.1016\/j.bbamcr.2026.120162_bb0085","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2017.377","article-title":"MiR-30c regulates cisplatin-induced apoptosis of renal tubular epithelial cells by targeting Bnip3L and Hspa5","volume":"8","author":"Du","year":"2017","journal-title":"Cell Death Dis."},{"issue":"10","key":"10.1016\/j.bbamcr.2026.120162_bb0090","doi-asserted-by":"crossref","DOI":"10.31083\/j.fbl2910360","article-title":"Study of the role of E2F1 and TMEM132A in prostate cancer development","volume":"29","author":"Wang","year":"2024","journal-title":"Frontiers in Bioscience-Landmark"},{"issue":"13","key":"10.1016\/j.bbamcr.2026.120162_bb0095","doi-asserted-by":"crossref","first-page":"4386","DOI":"10.7150\/jca.96396","article-title":"Multidimensional analysis of TMEM132A in pan-cancer: unveiling its potential as a biomarker for treatment response prediction","volume":"15","author":"Zhang","year":"2024","journal-title":"J. Cancer"},{"key":"10.1016\/j.bbamcr.2026.120162_bb0100","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2022.901559","article-title":"Effects of GLP-1 receptor agonists on biological behavior of colorectal cancer cells by regulating PI3K\/AKT\/mTOR signaling pathway","volume":"13","author":"Tong","year":"2022","journal-title":"Front. Pharmacol."},{"issue":"14","key":"10.1016\/j.bbamcr.2026.120162_bb0105","doi-asserted-by":"crossref","first-page":"3614","DOI":"10.1111\/febs.16768","article-title":"MAEL facilitates metabolic reprogramming and breast cancer progression by promoting the degradation of citrate synthase and fumarate hydratase via chaperone-mediated autophagy","volume":"290","author":"Zhou","year":"2023","journal-title":"FEBS J."},{"key":"10.1016\/j.bbamcr.2026.120162_bb0110","doi-asserted-by":"crossref","first-page":"5431","DOI":"10.2147\/DDDT.S282206","article-title":"Xanthohumol inhibits TGF-\u03b21-induced cardiac fibroblasts activation via mediating PTEN\/Akt\/mTOR signaling pathway","volume":"14","author":"Jiang","year":"2020","journal-title":"Drug Des. Devel. Ther."},{"issue":"2","key":"10.1016\/j.bbamcr.2026.120162_bb0115","doi-asserted-by":"crossref","first-page":"3356","DOI":"10.36922\/cp.3356","article-title":"Role of the IL-8\/CXCR2 axis in promoting vasculogenic mimicry in triple-negative breast cancer through epithelial-mesenchymal transition","volume":"6","author":"Abdulkarim","year":"2024","journal-title":"Cancer Plus"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Molecular Cell Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488926000601?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0167488926000601?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T10:11:37Z","timestamp":1783159897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0167488926000601"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["S0167488926000601"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamcr.2026.120162","relation":{},"ISSN":["0167-4889"],"issn-type":[{"value":"0167-4889","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"TMEM132A affects proliferation, invasion, and apoptosis via the \u03b2-catenin-dependent Wnt signaling in breast cancer","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbamcr.2026.120162","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"120162"}}