{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T06:09:29Z","timestamp":1790057369019,"version":"4.0.1"},"reference-count":52,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,11,19]],"date-time":"2014-11-19T00:00:00Z","timestamp":1416355200000},"content-version":"vor","delay-in-days":1571,"URL":"https:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"name":"National Science Foundation","award":["DBI-0649847"],"award-info":[{"award-number":["DBI-0649847"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Biomembranes"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.bbamem.2010.03.015","type":"journal-article","created":{"date-parts":[[2010,3,26]],"date-time":"2010-03-26T10:29:16Z","timestamp":1269599356000},"page":"1533-1539","source":"Crossref","is-referenced-by-count":23,"title":["Influence of lysophospholipid hydrolysis by the catalytic domain of neuropathy target esterase on the fluidity of bilayer lipid membranes"],"prefix":"10.1016","volume":"1798","author":[{"given":"Aaron J.","family":"Greiner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rudy J.","family":"Richardson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. Mark","family":"Worden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert Y.","family":"Ofoli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbamem.2010.03.015_bib1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/jat.2550060102","article-title":"Neuropathy target esterase in human-lymphocytes and platelets","volume":"6","author":"Maroni","year":"1986","journal-title":"J. Appl. Toxicol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib2","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1042\/bj3440625","article-title":"Neuropathy target esterase","volume":"344","author":"Glynn","year":"1999","journal-title":"Biochem. J."},{"key":"10.1016\/j.bbamem.2010.03.015_bib3","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/S0306-4522(97)00388-6","article-title":"Neuropathy target esterase: immunolocalization to neuronal cell bodies and axons","volume":"83","author":"Glynn","year":"1998","journal-title":"Neuroscience"},{"key":"10.1016\/j.bbamem.2010.03.015_bib4","doi-asserted-by":"crossref","first-page":"2865","DOI":"10.1523\/JNEUROSCI.5097-04.2005","article-title":"Loss of Swiss cheese\/neuropathy target esterase activity causes disruption of phosphatidylcholine homeostasis and neuronal and glial death in adult Drosophila","volume":"25","author":"Muehlig-Versen","year":"2005","journal-title":"J. Neurosci."},{"key":"10.1016\/j.bbamem.2010.03.015_bib5","doi-asserted-by":"crossref","first-page":"8820","DOI":"10.1074\/jbc.M210743200","article-title":"Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in mammalian cells","volume":"278","author":"Li","year":"2003","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib6","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1016\/0006-2952(87)90630-7","article-title":"Kinetics of heat inactivation of phenyl valerate hydrolases from hen and rat-brain","volume":"36","author":"Reiner","year":"1987","journal-title":"Biochem. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib7","doi-asserted-by":"crossref","first-page":"7983","DOI":"10.1073\/pnas.1232473100","article-title":"Evidence that mouse brain neuropathy target esterase is a lysophospholipase","volume":"100","author":"Quistad","year":"2003","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbamem.2010.03.015_bib8","doi-asserted-by":"crossref","first-page":"20942","DOI":"10.1074\/jbc.M200330200","article-title":"Human neuropathy target esterase catalyzes hydrolysis of membrane lipids","volume":"277","author":"van Tienhoven","year":"2002","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib9","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1016\/j.taap.2008.07.015","article-title":"Cellular function of neuropathy target esterase in lysophosphatidylcholine action","volume":"232","author":"Vose","year":"2008","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib10","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.taap.2007.06.008","article-title":"Lysophosphatidylcholine hydrolases of human erythrocytes, lymphocytes, and brain: Sensitive targets of conserved specificity for organophosphorus delayed neurotoxicants","volume":"224","author":"Vose","year":"2007","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib11","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3200\/AEOH.58.8.484-497","article-title":"Organophosphorus ester-induced chronic neurotoxicity","volume":"58","author":"Abou-Donia","year":"2003","journal-title":"Arch. Environ. Health"},{"key":"10.1016\/j.bbamem.2010.03.015_bib12","first-page":"133","article-title":"Neurological syndromes of organophosphorus compounds","volume":"16","author":"Jamal","year":"1997","journal-title":"Adverse Drug React. Toxicol. Rev."},{"key":"10.1016\/j.bbamem.2010.03.015_bib13","series-title":"Biomarkers and biosensors of delayed neuropathic agents, handbook of toxicology of chemical warfare agents, chapter 57","first-page":"859","author":"Richardson","year":"2009"},{"key":"10.1016\/j.bbamem.2010.03.015_bib14","doi-asserted-by":"crossref","first-page":"3716","DOI":"10.1021\/bi049960e","article-title":"The mipafox-inhibited catalytic domain of human neuropathy target esterase ages by reversible proton loss","volume":"43","author":"Kropp","year":"2004","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamem.2010.03.015_bib15","doi-asserted-by":"crossref","unstructured":"S.J. Wijeyesakere and R.J. Richardson, Neuropathy Target Esterase, in: R. Krieger (Ed.), Hayes' Handbook of Pesticide Toxicology, Chapter 67, 3rd ed., Elsevier\/Academic Press, San Diego, Oxford, UK, (in press) 64, pp. 1435\u20131478.","DOI":"10.1016\/B978-0-12-374367-1.00067-7"},{"key":"10.1016\/j.bbamem.2010.03.015_bib16","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1016\/j.ajhg.2007.12.018","article-title":"Neuropathy target esterase gene mutations cause motor neuron disease","volume":"82","author":"Rainier","year":"2008","journal-title":"Am. J. Hum. Genet."},{"key":"10.1016\/j.bbamem.2010.03.015_bib17","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0892-0362(91)90004-G","article-title":"Development of esterase-activities in the chicken before and after hatching","volume":"13","author":"Farageelawar","year":"1991","journal-title":"Neurotoxicol. Teratol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib18","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/0041-008X(84)90334-X","article-title":"Neurotoxic and teratogenic effects of an organo-phosphorus insecticide (phenyl phosphonothioic acid-O-ethyl-O-[4-nitrophenyl] ester) on mallard development","volume":"73","author":"Hoffman","year":"1984","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib19","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1016\/0041-008X(92)90240-S","article-title":"Local application of neuropathic organophosphorus compounds to hen sciatic-nerve\u2014inhibition of neuropathy target esterase and peripheral neurological impairments","volume":"117","author":"Carrera","year":"1992","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib20","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/S0301-0082(99)00043-X","article-title":"Neural development and neurodegeneration: two faces of neuropathy target esterase","volume":"61","author":"Glynn","year":"2000","journal-title":"Prog. Neurobiol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib21","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1529\/biophysj.105.069435","article-title":"Effect of average phospholipid curvature on supported bilayer formation on glass by vesicle fusion","volume":"90","author":"Hamai","year":"2006","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamem.2010.03.015_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1388-1981(99)00063-3","article-title":"Mammalian lysophospholipases","volume":"1439","author":"Wang","year":"1999","journal-title":"Biochim. Biophys. Acta-Mol. Cell Biol. Lipids"},{"key":"10.1016\/j.bbamem.2010.03.015_bib23","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/S0021-9150(97)00295-5","article-title":"Lysophosphatidylcholine induces the production of IL-1 beta by human monocytes","volume":"137","author":"Liu-Wu","year":"1998","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bbamem.2010.03.015_bib24","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.neuro.2008.11.013","article-title":"Neurotoxicity of inverted-cone shaped lipids","volume":"30","author":"Caccin","year":"2009","journal-title":"Neurotoxicology"},{"key":"10.1016\/j.bbamem.2010.03.015_bib25","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1126\/science.1120640","article-title":"Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures","volume":"310","author":"Rigoni","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bbamem.2010.03.015_bib26","doi-asserted-by":"crossref","first-page":"11238","DOI":"10.1074\/jbc.M610176200","article-title":"Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products","volume":"282","author":"Rigoni","year":"2007","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib27","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1111\/j.1432-1033.1993.tb17676.x","article-title":"Glycerophosphocholine release in human erythrocytes\u2014H-1 spin-echo and P-31-Nmr evidence for lysophospholipase","volume":"212","author":"Selle","year":"1993","journal-title":"Eur. J. Biochem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib28","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.taap.2004.01.005","article-title":"Lysophospholipase inhibition by organophosphorus toxicants","volume":"196","author":"Quistad","year":"2004","journal-title":"Toxicol. Appl. Pharmacol."},{"key":"10.1016\/j.bbamem.2010.03.015_bib29","doi-asserted-by":"crossref","first-page":"5196","DOI":"10.1021\/ac0701684","article-title":"Nanostructured biosensor for measuring neuropathy target esterase activity","volume":"79","author":"Kohli","year":"2007","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib30","doi-asserted-by":"crossref","first-page":"24477","DOI":"10.1074\/jbc.M002921200","article-title":"Membrane association of and critical residues in the catalytic domain of human neuropathy target esterase","volume":"275","author":"Atkins","year":"2000","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib31","doi-asserted-by":"crossref","first-page":"18513","DOI":"10.1074\/jbc.M800440200","article-title":"Plasma membrane cholesterol content affects nitric oxide diffusion dynamics and signaling","volume":"283","author":"Miersch","year":"2008","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib32","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1021\/bi00561a010","article-title":"Cell to vesicle transfer of intrinsic membrane-proteins\u2014effect of membrane fluidity","volume":"19","author":"Cook","year":"1980","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamem.2010.03.015_bib33","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1021\/bi00352a015","article-title":"Correlation between acetylcholine-receptor function and structural-properties of membranes","volume":"25","author":"Fong","year":"1986","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamem.2010.03.015_bib34","doi-asserted-by":"crossref","first-page":"15890","DOI":"10.1021\/jp049845d","article-title":"Influence of lipid chemistry on the osmotic response of cell membranes: Effect of non-bilayer forming lipids","volume":"108","author":"Hull","year":"2004","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bbamem.2010.03.015_bib35","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0003-2697(80)90511-4","article-title":"Enzymatic determination of serum-free fatty-acids\u2014a colorimetric method","volume":"107","author":"Shimizu","year":"1980","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib36","doi-asserted-by":"crossref","first-page":"2649","DOI":"10.1021\/jp003631o","article-title":"Lipid membrane partitioning of lysolipids and fatty acids: effects of membrane phase structure and detergent chain length","volume":"105","author":"Hoyrup","year":"2001","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bbamem.2010.03.015_bib37","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1021\/la9911436","article-title":"Quantitative technique for investigating macromolecular adsorption and interactions at the liquid-liquid interface","volume":"16","author":"Gajraj","year":"2000","journal-title":"Langmuir"},{"key":"10.1016\/j.bbamem.2010.03.015_bib38","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/S0006-3495(81)84717-0","article-title":"Measurement of rotational motion in membranes using fluorescence recovery after photobleaching","volume":"36","author":"Smith","year":"1981","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamem.2010.03.015_bib39","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0301-4622(02)00037-6","article-title":"Fluorescence pattern photobleaching recovery for samples with multi-component diffusion","volume":"97","author":"Starr","year":"2002","journal-title":"Biophys. Chem."},{"key":"10.1016\/j.bbamem.2010.03.015_bib40","doi-asserted-by":"crossref","first-page":"S2469","DOI":"10.1088\/0953-8984\/16\/26\/020","article-title":"Phospholipid bilayer formation at a bare Si surface: a time-resolved neutron reflectivity study","volume":"16","author":"Gutberlet","year":"2004","journal-title":"J. Phys. Condens. Matter"},{"key":"10.1016\/j.bbamem.2010.03.015_bib41","doi-asserted-by":"crossref","first-page":"5067","DOI":"10.1021\/bi00136a020","article-title":"Functional reconstitution of the nicotinic acetylcholine-receptor by CHAPS dialysis depends on the concentrations of salt, lipid, and protein","volume":"31","author":"Schurholz","year":"1992","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbamem.2010.03.015_bib42","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/j.bbamem.2004.04.011","article-title":"Membrane proteins, lipids and detergents: not just a soap opera","volume":"1666","author":"Seddon","year":"2004","journal-title":"Biochim. Biophys. Acta-Biomembr."},{"key":"10.1016\/j.bbamem.2010.03.015_bib43","doi-asserted-by":"crossref","first-page":"4317","DOI":"10.1073\/pnas.79.14.4317","article-title":"Lateral and rotational diffusion of bacteriorhodopsin in lipid bilayers\u2014experimental test of the Saffman\u2013Delbruck equations","volume":"79","author":"Peters","year":"1982","journal-title":"Proc. Natl. Acad. Sci. U. S. A. -Biol. Sci."},{"key":"10.1016\/j.bbamem.2010.03.015_bib44","doi-asserted-by":"crossref","first-page":"3727","DOI":"10.1529\/biophysj.106.084590","article-title":"Influence of lipid chemistry on membrane fluidity: Tail and headgroup interactions","volume":"91","author":"Seu","year":"2006","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamem.2010.03.015_bib45","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.colsurfb.2009.03.019","article-title":"Effect of saturation degree on the interactions between fatty acids and phosphatidylcholines in binary and ternary Langmuir monolayers","volume":"72","author":"Hac-Wydro","year":"2009","journal-title":"Colloids Surf. B Biointerfaces"},{"key":"10.1016\/j.bbamem.2010.03.015_bib46","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0009-3084(00)00170-5","article-title":"Effect of fatty acids on phase behavior of hydrated dipalmitoylphosphatidylcholine bilayer: saturated versus unsaturated fatty acids","volume":"109","author":"Inoue","year":"2001","journal-title":"Chem. Phys. Lipids"},{"key":"10.1016\/j.bbamem.2010.03.015_bib47","doi-asserted-by":"crossref","first-page":"391","DOI":"10.3109\/00365519509104978","article-title":"Effect of free fatty-acids on the structure and properties of erythrocyte-membrane","volume":"55","author":"Lapshina","year":"1995","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"10.1016\/j.bbamem.2010.03.015_bib48","first-page":"123","article-title":"Effect of free fatty acids on erythrocyte morphology and membrane fluidity","volume":"42","author":"Zavodnik","year":"1997","journal-title":"Biochem. Mol. Biol. Int."},{"key":"10.1016\/j.bbamem.2010.03.015_bib49","doi-asserted-by":"crossref","first-page":"1508","DOI":"10.1016\/j.bbamem.2009.04.002","article-title":"The role of fatty acid unsaturation in minimizing biophysical changes on the structure and local effects of bilayer membranes","volume":"1788","author":"Leekumjorn","year":"2009","journal-title":"Biochim. Biophys. Acta-Biomembr."},{"key":"10.1016\/j.bbamem.2010.03.015_bib50","doi-asserted-by":"crossref","first-page":"2869","DOI":"10.1529\/biophysj.107.120717","article-title":"Experimental and computational studies investigating trehalose protection of HepG2 cells from palmitate-induced toxicity","volume":"94","author":"Leekumjorn","year":"2008","journal-title":"Biophys. J."},{"key":"10.1016\/j.bbamem.2010.03.015_bib51","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1021\/jp806205m","article-title":"Effects of fatty acid inclusion in a DMPC bilayer membrane","volume":"113","author":"Peters","year":"2009","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bbamem.2010.03.015_bib52","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.chemphyslip.2007.06.213","article-title":"The influence of fatty acids on model cholesterol\/phospholipid membranes","volume":"150","author":"Hac-Wydro","year":"2007","journal-title":"Chem. Phys. Lipids"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Biomembranes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0005273610001148?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0005273610001148?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,5,6]],"date-time":"2020-05-06T15:12:33Z","timestamp":1588777953000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0005273610001148"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":52,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0005273610001148"],"URL":"https:\/\/doi.org\/10.1016\/j.bbamem.2010.03.015","relation":{},"ISSN":["0005-2736"],"issn-type":[{"value":"0005-2736","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}