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Gargouri, S. Giannattasio, P. Goffrini, C.W. Gourlay, C.M. Grant, M.T. Greenwood, N. Guaragnella, T. Heger, J. Heinisch, E. Herker, J.M. Herrmann, S. Hofer, A. Jim\u00e9nez-Ruiz, H. Jungwirth, K. Kainz, D.P. Kontoyiannis, P. Ludovico, S. Manon, E. Martegani, C. Mazzoni, L.A. Megeney, C. Meisinger, J. Nielsen, T. Nystr\u00f6m, H.D. Osiewacz, T.F. Outeiro, H.-O. Park, T. Pendl, D. Petranovic, S. Picot, P. Pol\u010dic, T. Powers, M. Ramsdale, M. Rinnerthaler, P. Rockenfeller, C. Ruckenstuhl, R. Schaffrath, M. Segovia, F.F. Severin, A. Sharon, S.J. Sigrist, C. Sommer-Ruck, M.J. Sousa, J.M. Thevelein, K. Thevissen, V. Titorenko, M.B. Toledano, M. Tuite, F.-N. V\u00f6gtle, B. Westermann, J. Winderickx, S. Wissing, S. W\u00f6lfl, Z.J. Zhang, R.Y. Zhao, B. Zhou, L. Galluzzi, G. Kroemer, F. Madeo, Guidelines and recommendations on yeast cell death nomenclature., Microb. Cell (Graz, Austria). 5 (2018) 4\u201331. doi:10.15698\/mic2018.01.607.","DOI":"10.15698\/mic2018.01.607"},{"key":"10.1016\/j.bbamem.2019.183032_bb0320","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.mycmed.2018.02.007","article-title":"Evaluation of biofilm formation ability in different Candida strains and anti-biofilm effects of Fe3O4-NPs compared with fluconazole: an in vitro study","volume":"28","author":"Salari","year":"2018","journal-title":"J. Mycol. 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