{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T02:32:05Z","timestamp":1790649125051,"version":"4.1.0"},"reference-count":44,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2016,4,1]],"date-time":"2016-04-01T00:00:00Z","timestamp":1459468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100003074","name":"ANPCyT","doi-asserted-by":"publisher","award":["BID 1728 OC-AR PICT 2010-1494"],"award-info":[{"award-number":["BID 1728 OC-AR PICT 2010-1494"]}],"id":[{"id":"10.13039\/501100003074","id-type":"DOI","asserted-by":"publisher"}]},{"name":"PIP","award":["2010-0190"],"award-info":[{"award-number":["2010-0190"]}]},{"name":"Vermont Genetics Network","award":["P20GM103449"],"award-info":[{"award-number":["P20GM103449"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics"],"published-print":{"date-parts":[[2016,4]]},"DOI":"10.1016\/j.bbapap.2016.01.010","type":"journal-article","created":{"date-parts":[[2016,1,26]],"date-time":"2016-01-26T07:00:47Z","timestamp":1453791647000},"page":"400-408","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Identification of new palmitoylated proteins in Toxoplasma gondii"],"prefix":"10.1016","volume":"1864","author":[{"given":"Marina C.","family":"Caballero","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e9s M.","family":"Alonso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4355-3102","authenticated-orcid":false,"given":"Marcia","family":"Attias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wanderley","family":"de Souza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda M.","family":"Corvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbapap.2016.01.010_bb0005","doi-asserted-by":"crossref","first-page":"4311","DOI":"10.1021\/bi034159a","article-title":"New insights into the mechanisms of protein palmitoylation","volume":"42","author":"Linder","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0010","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1080\/09687680802649582","article-title":"Ras acylation, compartmentalization and signaling nanoclusters (review)","volume":"26","author":"Henis","year":"2009","journal-title":"Mol. Membr. Biol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0015","doi-asserted-by":"crossref","first-page":"3294","DOI":"10.1091\/mbc.E02-02-0095","article-title":"Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi","volume":"13","author":"Michaelson","year":"2002","journal-title":"Mol. Biol. Cell"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0020","doi-asserted-by":"crossref","first-page":"6498","DOI":"10.1016\/S0021-9258(17)37399-4","article-title":"Regulation of enzymatic activity by active site fatty acylation. A new role for long chain fatty acid acylation of proteins","volume":"269","author":"Berthiaume","year":"1994","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0025","doi-asserted-by":"crossref","first-page":"45704","DOI":"10.1074\/jbc.M102766200","article-title":"Regulation of mitochondrial carbamoyl-phosphate synthetase 1 activity by active site fatty acylation","volume":"276","author":"Corvi","year":"2001","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0030","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.1111\/febs.12263","article-title":"What does S-palmitoylation do to membrane proteins?","volume":"280","author":"Blaskovic","year":"2013","journal-title":"FEBS J."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0035","doi-asserted-by":"crossref","first-page":"1914","DOI":"10.1096\/fj.09-149765","article-title":"Palmitoylation of ketogenic enzyme HMGCS2 enhances its interaction with PPARalpha and transcription at the Hmgcs2 PPRE","volume":"24","author":"Kostiuk","year":"2010","journal-title":"FASEB J."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0040","doi-asserted-by":"crossref","first-page":"14572","DOI":"10.1073\/pnas.1105262108","article-title":"Palmitoylation controls the dynamics of budding-yeast heterochromatin via the telomere-binding protein Rif1","volume":"108","author":"Park","year":"2011","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001094","article-title":"A novel family of Toxoplasma IMC proteins displays a hierarchical organization and functions in coordinating parasite division","volume":"6","author":"Beck","year":"2010","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0050","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.molbiopara.2012.05.002","article-title":"Toxoplasma ISP4 is a central IMC sub-compartment protein whose localization depends on palmitoylation but not myristoylation","volume":"184","author":"Fung","year":"2012","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0055","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1600-0854.2010.01148.x","article-title":"Unusual anchor of a motor complex (MyoD-MLC2) to the plasma membrane of Toxoplasma gondii","volume":"12","author":"Polonais","year":"2011","journal-title":"Traffic"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0060","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.bbamcr.2013.02.022","article-title":"N-terminal palmitoylation is required for Toxoplasma gondii HSP20 inner membrane complex localization","volume":"1833","author":"De Napoli","year":"2013","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0065","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0166-6851(01)00451-0","article-title":"Molecular characterization of a coccidian parasite cGMP dependent protein kinase","volume":"120","author":"Donald","year":"2002","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0070","doi-asserted-by":"crossref","first-page":"1335","DOI":"10.1111\/j.1600-0854.2012.01394.x","article-title":"Dissection of minimal sequence requirements for rhoptry membrane targeting in the malaria parasite","volume":"13","author":"Cabrera","year":"2012","journal-title":"Traffic"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0075","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1016\/j.chom.2015.09.006","article-title":"Global analysis of palmitoylated proteins in Toxoplasma gondii","volume":"18","author":"Foe","year":"2015","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0080","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.molbiopara.2012.03.006","article-title":"Protein palmitoylation inhibition by 2-bromopalmitate alters gliding, host cell invasion and parasite morphology in Toxoplasma gondii","volume":"184","author":"Alonso","year":"2012","journal-title":"Mol. Biochem. Parasitol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0085","doi-asserted-by":"crossref","DOI":"10.1038\/nchembio.1315","article-title":"Small-molecule inhibition of a depalmitoylase enhances Toxoplasma host-cell invasion","author":"Child","year":"2013","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0090","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1111\/tra.12081","article-title":"Global analysis of apicomplexan protein S-acyl transferases reveals an enzyme essential for invasion","volume":"14","author":"Frenal","year":"2013","journal-title":"Traffic"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0095","doi-asserted-by":"crossref","first-page":"14010","DOI":"10.1074\/jbc.271.24.14010","article-title":"Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine\u2013xanthine\u2013guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation","volume":"271","author":"Donald","year":"1996","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0100","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/S0091-679X(08)61845-2","article-title":"Molecular tools for genetic dissection of the protozoan parasite Toxoplasma gondii","volume":"45","author":"Roos","year":"1994","journal-title":"Methods Cell Biol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0105","doi-asserted-by":"crossref","first-page":"1573","DOI":"10.1038\/nprot.2007.225","article-title":"Palmitoylated proteins: purification and identification","volume":"2","author":"Wan","year":"2007","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0110","doi-asserted-by":"crossref","first-page":"2380","DOI":"10.1016\/j.jprot.2011.05.039","article-title":"Proteomic profiling of acrolein adducts in human lung epithelial cells","volume":"74","author":"Spiess","year":"2011","journal-title":"J. Proteome"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0115","doi-asserted-by":"crossref","first-page":"D553","DOI":"10.1093\/nar\/gkm981","article-title":"ToxoDB: an integrated Toxoplasma gondii database resource","volume":"36","author":"Gajria","year":"2008","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0120","doi-asserted-by":"crossref","first-page":"D344","DOI":"10.1093\/nar\/gks1067","article-title":"New and continuing developments at PROSITE","volume":"41","author":"Sigrist","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0125","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1038\/nmeth.1701","article-title":"SignalP 4.0: discriminating signal peptides from transmembrane regions","volume":"8","author":"Petersen","year":"2011","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0130","first-page":"147","article-title":"Better prediction of protein cellular localization sites with the k nearest neighbors classifier","volume":"5","author":"Horton","year":"1997","journal-title":"Proc. Int. Conf. Intell. Syst. Mol. Biol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0135","doi-asserted-by":"crossref","first-page":"639","DOI":"10.1093\/protein\/gzn039","article-title":"CSS-Palm 2.0: an updated software for palmitoylation sites prediction","volume":"21","author":"Ren","year":"2008","journal-title":"Protein Eng. Des. Sel."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0140","doi-asserted-by":"crossref","first-page":"1626","DOI":"10.1002\/pmic.200300783","article-title":"N-terminal myristoylation predictions by ensembles of neural networks","volume":"4","author":"Bologna","year":"2004","journal-title":"Proteomics"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0145","doi-asserted-by":"crossref","first-page":"R55","DOI":"10.1186\/gb-2005-6-6-r55","article-title":"Refinement and prediction of protein prenylation motifs","volume":"6","author":"Maurer-Stroh","year":"2005","journal-title":"Genome Biol."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0150","doi-asserted-by":"crossref","first-page":"276","DOI":"10.2144\/04362RR02","article-title":"Labeling and quantifying sites of protein palmitoylation","volume":"36","author":"Drisdel","year":"2004","journal-title":"Biotechniques"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0155","doi-asserted-by":"crossref","first-page":"2723","DOI":"10.1073\/pnas.051629998","article-title":"Subcellular localization of acetyl-CoA carboxylase in the apicomplexan parasite Toxoplasma gondii","volume":"98","author":"Jelenska","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0160","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02357-14","article-title":"Novel components of the Toxoplasma inner membrane complex revealed by BioID","volume":"6","author":"Chen","year":"2015","journal-title":"MBio"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0165","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1042\/BST20140289","article-title":"Palmitoylation and palmitoyl-transferases in Plasmodium parasites","volume":"43","author":"Hodson","year":"2015","journal-title":"Biochem. Soc. Trans."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0170","doi-asserted-by":"crossref","first-page":"38104","DOI":"10.1074\/jbc.M110.169102","article-title":"Mutational analysis of Saccharomyces cerevisiae Erf2 reveals a two-step reaction mechanism for protein palmitoylation by DHHC enzymes","volume":"285","author":"Mitchell","year":"2010","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0175","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003049","article-title":"A forward genetic screen reveals that calcium-dependent protein kinase 3 regulates egress in Toxoplasma","volume":"8","author":"Garrison","year":"2012","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0180","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.chom.2010.09.002","article-title":"Functional dissection of the apicomplexan glideosome molecular architecture","volume":"8","author":"Frenal","year":"2010","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0185","doi-asserted-by":"crossref","first-page":"251","DOI":"10.4161\/nucl.20391","article-title":"Palmitoylation in the nucleus: a little fat around the edges","volume":"3","author":"Fox","year":"2012","journal-title":"Nucleus"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0190","doi-asserted-by":"crossref","first-page":"31350","DOI":"10.1074\/jbc.C113.511261","article-title":"Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins","volume":"288","author":"Feldman","year":"2013","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0195","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.scr.2013.12.010","article-title":"2-Bromopalmitate modulates neuronal differentiation through the regulation of histone acetylation","volume":"12","author":"Chen","year":"2014","journal-title":"Stem Cell Res."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0200","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1096\/fj.07-9199com","article-title":"Identification of palmitoylated mitochondrial proteins using a bio-orthogonal azido-palmitate analogue","volume":"22","author":"Kostiuk","year":"2008","journal-title":"FASEB J."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0205","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.chom.2014.04.002","article-title":"The Toxoplasma pseudokinase ROP5 forms complexes with ROP18 and ROP17 kinases that synergize to control acute virulence in mice","volume":"15","author":"Etheridge","year":"2014","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bbapap.2016.01.010_bb0210","doi-asserted-by":"crossref","first-page":"34245","DOI":"10.1074\/jbc.M504158200","article-title":"Proteomic analysis of rhoptry organelles reveals many novel constituents for host\u2013parasite interactions in Toxoplasma gondii","volume":"280","author":"Bradley","year":"2005","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0215","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1003162","article-title":"A Toxoplasma palmitoyl acyl transferase and the palmitoylated armadillo repeat protein TgARO govern apical rhoptry tethering and reveal a critical role for the rhoptries in host cell invasion but not egress","volume":"9","author":"Beck","year":"2013","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.bbapap.2016.01.010_bb0220","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1016\/j.chom.2012.06.005","article-title":"Analysis of protein palmitoylation reveals a pervasive role in Plasmodium development and pathogenesis","volume":"12","author":"Jones","year":"2012","journal-title":"Cell Host Microbe"}],"container-title":["Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570963916300024?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570963916300024?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,6,2]],"date-time":"2022-06-02T12:32:52Z","timestamp":1654173172000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570963916300024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,4]]},"references-count":44,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2016,4]]}},"alternative-id":["S1570963916300024"],"URL":"https:\/\/doi.org\/10.1016\/j.bbapap.2016.01.010","relation":{},"ISSN":["1570-9639"],"issn-type":[{"value":"1570-9639","type":"print"}],"subject":[],"published":{"date-parts":[[2016,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of new palmitoylated proteins in Toxoplasma gondii","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbapap.2016.01.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}