{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T22:19:57Z","timestamp":1778624397875,"version":"3.51.4"},"reference-count":60,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,7,1]],"date-time":"2021-07-01T00:00:00Z","timestamp":1625097600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["307377\/2019-9"],"award-info":[{"award-number":["307377\/2019-9"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/07467-1"],"award-info":[{"award-number":["2013\/07467-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/14651-3"],"award-info":[{"award-number":["2013\/14651-3"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2016\/16935-7"],"award-info":[{"award-number":["2016\/16935-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2013\/13548-4"],"award-info":[{"award-number":["2013\/13548-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics"],"published-print":{"date-parts":[[2021,7]]},"DOI":"10.1016\/j.bbapap.2021.140643","type":"journal-article","created":{"date-parts":[[2021,3,14]],"date-time":"2021-03-14T00:53:02Z","timestamp":1615683182000},"page":"140643","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"title":["The distinct N-terminomes of Bothrops jararaca newborn and adult venoms"],"prefix":"10.1016","volume":"1869","author":[{"given":"D\u00e9bora","family":"Andrade-Silva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Milton Y.","family":"Nishiyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel R.","family":"Stuginski","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andr\u00e9","family":"Zelanis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Solange M.T.","family":"Serrano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bbapap.2021.140643_bb0005","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1016\/0041-0101(91)90116-9","article-title":"Snake venom variability: methods of study, results and interpretation","volume":"29","author":"Chippaux","year":"1991","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0010","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/379537a0","article-title":"Diet and snake venom evolution","volume":"379","author":"Daltry","year":"1996","journal-title":"Nature."},{"key":"10.1016\/j.bbapap.2021.140643_bb0015","doi-asserted-by":"crossref","first-page":"666","DOI":"10.3390\/toxins11110666","article-title":"The diversity of venom: The importance of behavior and venom system morphology in understanding its ecology and evolution","volume":"11","author":"Schendel","year":"2019","journal-title":"Toxins (Basel)."},{"key":"10.1016\/j.bbapap.2021.140643_bb0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.tips.2020.05.006","article-title":"Causes and consequences of snake venom variation","author":"Casewell","year":"2020","journal-title":"Trends Pharmacol. Sci."},{"key":"10.1016\/j.bbapap.2021.140643_bb0025","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1016\/j.febslet.2009.03.029","article-title":"Venoms, venomics, antivenomics","volume":"583","author":"Calvete","year":"2009","journal-title":"FEBS Lett."},{"key":"10.1016\/j.bbapap.2021.140643_bb0030","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.toxicon.2012.02.013","article-title":"The structural and functional diversification of the Toxicofera reptile venom system","volume":"60","author":"Fry","year":"2012","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0035","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tree.2012.10.020","article-title":"Complex cocktails: the evolutionary novelty of venoms","volume":"28","author":"Casewell","year":"2013","journal-title":"Trends Ecol. Evol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/toxins8090263","article-title":"A tricky trait: Applying the fruits of the \u201cfunction debate\u201d in the philosophy of biology to the \u201cvenom debate\u201d in the science of toxinology","volume":"8","author":"Jackson","year":"2016","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.bbapap.2021.140643_bb0045","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.toxicon.2012.11.022","article-title":"The venom optimization hypothesis revisited","volume":"63","author":"Morgenstern","year":"2013","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0050","doi-asserted-by":"crossref","first-page":"332","DOI":"10.3389\/fevo.2019.00332","article-title":"Snake venom in context: neglected clades and concepts","volume":"7","author":"Jackson","year":"2019","journal-title":"Front. Ecol. Evol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0055","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1002\/pmic.200700777","article-title":"Exploring snake venom proteomes: multifaceted analyses for complex toxin mixtures","volume":"8","author":"Fox","year":"2008","journal-title":"Proteomics."},{"key":"10.1016\/j.bbapap.2021.140643_bb0060","doi-asserted-by":"crossref","first-page":"2851","DOI":"10.1007\/s00018-009-0050-2","article-title":"Protein complexes in snake venom","volume":"66","author":"Doley","year":"2009","journal-title":"Cell. Mol. Life Sci."},{"key":"10.1016\/j.bbapap.2021.140643_bb0065","doi-asserted-by":"crossref","first-page":"2658","DOI":"10.1021\/acs.jproteome.6b00217","article-title":"Proteomic and glycoproteomic profilings reveal that post-translational modifications of toxins contribute to venom phenotype in snakes","volume":"15","author":"Andrade-Silva","year":"2016","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0070","doi-asserted-by":"crossref","DOI":"10.1074\/mcp.RA118.000748","article-title":"Structures of N-Glycans of Bothrops venoms revealed as molecular signatures that contribute to venom phenotype in viperid snakes","author":"Andrade-Silva","year":"2018","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0075","doi-asserted-by":"crossref","first-page":"136","DOI":"10.3390\/toxins11030136","article-title":"Structurally robust and functionally highly versatile\u2014C-type lectin (\u2212related) proteins in snake venoms","volume":"11","author":"Eble","year":"2019","journal-title":"Toxins (Basel)."},{"key":"10.1016\/j.bbapap.2021.140643_bb0080","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41598-019-38861-8","article-title":"SDS-induced oligomerization of Lys49-phospholipase A 2 from snake venom","volume":"9","author":"Matsui","year":"2019","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bbapap.2021.140643_bb0085","series-title":"The Venomous Reptiles of the Western Hemisphere","volume":"vol. I","author":"Campbell","year":"2004"},{"key":"10.1016\/j.bbapap.2021.140643_bb0090","series-title":"Venom. Anim. Their Venoms, Academic, New York","first-page":"345","article-title":"Symptomatology, pathology and treatment of snake bites in South America","author":"Rosenfeld","year":"1971"},{"key":"10.1016\/j.bbapap.2021.140643_bb0095","series-title":"Venom. Reptil. West. Hemisph., Ithaca","first-page":"709","article-title":"Snakebites in central and South America: Epidemiology, clnical geatures and clinical management","author":"Warrell","year":"2004"},{"key":"10.1016\/j.bbapap.2021.140643_bb0100","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1016\/j.toxicon.2008.03.018","article-title":"Haematological evaluation of patients bitten by the jararaca, Bothrops jararaca, in Brazil","volume":"51","author":"Santoro","year":"2008","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0105","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/pmic.200400931","article-title":"A multifaceted analysis of viperid snake venoms by two-dimensional gel electrophoresis: an approach to understanding venom proteomics","volume":"5","author":"Serrano","year":"2005","journal-title":"Proteomics."},{"key":"10.1016\/j.bbapap.2021.140643_bb0110","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.trstmh.2005.09.003","article-title":"Underestimation of snakebite mortality by hospital statistics in the Monaragala District of Sri Lanka","volume":"100","author":"Fox","year":"2006","journal-title":"Trans. R. Soc. Trop. Med. Hyg."},{"key":"10.1016\/j.bbapap.2021.140643_bb0115","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1002\/pmic.200800484","article-title":"Analysis of the subproteomes of proteinases and heparin-binding toxins of eight Bothrops venoms","volume":"9","author":"Leme","year":"2009","journal-title":"Proteomics."},{"key":"10.1016\/j.bbapap.2021.140643_bb0120","doi-asserted-by":"crossref","first-page":"4218","DOI":"10.1002\/pmic.201100287","article-title":"Bothrops jararaca venom proteome rearrangement upon neonate to adult transition","volume":"11","author":"Zelanis","year":"2011","journal-title":"Proteomics."},{"key":"10.1016\/j.bbapap.2021.140643_bb0125","doi-asserted-by":"crossref","first-page":"4585","DOI":"10.1021\/pr4007393","article-title":"Individual variability in the venom proteome of juvenile Bothrops jararaca specimens","volume":"12","author":"Dias","year":"2013","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0130","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1074\/mcp.M112.019331","article-title":"Peptidomics of three Bothrops snake venoms: insights into the molecular diversification of proteomes and peptidomes","volume":"11","author":"Tashima","year":"2012","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0135","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.jprot.2015.04.029","article-title":"Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest","volume":"135","author":"Gon\u00e7alves-Machado","year":"2016","journal-title":"J. Proteome"},{"key":"10.1016\/j.bbapap.2021.140643_bb0140","first-page":"143","article-title":"Coagulant and fibrinolytic activity of animal venoms; determination of coagulant and fibrinolytic index of different species","volume":"29","author":"Rosenfeld","year":"1959","journal-title":"Mem. Inst. Butantan."},{"key":"10.1016\/j.bbapap.2021.140643_bb0145","doi-asserted-by":"crossref","first-page":"1443","DOI":"10.1016\/j.toxicon.2010.08.011","article-title":"Comparative analysis of newborn and adult Bothrops jararaca snake venoms","volume":"56","author":"Antunes","year":"2010","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0150","series-title":"Biol. Vipers","first-page":"307","article-title":"Ecological and phylogenetic correlates of feeding habits in neotropical pitvipers of the genus B othrops","author":"Martins","year":"2002"},{"key":"10.1016\/j.bbapap.2021.140643_bb0155","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.toxicon.2005.11.007","article-title":"Sex-based individual variation of snake venom proteome among eighteen Bothrops jararaca siblings","volume":"47","author":"Menezes","year":"2006","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0160","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1002\/rcm.2931","article-title":"Mass spectrometric analysis of the individual variability of Bothrops jararaca venom peptide fraction. Evidence for sex-based variation among the bradykinin-potentiating peptides","volume":"21","author":"Pimenta","year":"2007","journal-title":"Rapid Commun. Mass Spectrom."},{"key":"10.1016\/j.bbapap.2021.140643_bb0165","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1016\/j.jprot.2011.09.017","article-title":"N-glycome profiling of Bothrops jararaca newborn and adult venoms","volume":"75","author":"Zelanis","year":"2012","journal-title":"J. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0001554","article-title":"A transcriptomic view of the proteome variability of newborn and adult Bothrops jararaca snake venoms","volume":"6","author":"Zelanis","year":"2012","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.bbapap.2021.140643_bb0175","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.jprot.2016.02.030","article-title":"Proteomic identification of gender molecular markers in Bothrops jararaca venom","volume":"139","author":"Zelanis","year":"2016","journal-title":"J. Proteomics"},{"issue":"2","key":"10.1016\/j.bbapap.2021.140643_bb0180","doi-asserted-by":"crossref","first-page":"1341","DOI":"10.1021\/acs.jproteome.0c00737","article-title":"Venom profiling of the insular species Bothrops alcatraz: characterization of proteome, glycoproteome, and N-terminome using terminal amine isotopic labeling of substrates","volume":"20","author":"Andrade-Silva","year":"2021","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0185","doi-asserted-by":"crossref","first-page":"2513","DOI":"10.1074\/mcp.M113.031591","article-title":"Accurate proteome-wide label-free quantification by delayed normalization and maximal peptide ratio extraction, termed MaxLFQ","volume":"13","author":"Cox","year":"2014","journal-title":"Mol. Cell. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0190","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1038\/nbt.2839","article-title":"ProteomeXchange provides globally coordinated proteomics data submission and dissemination","volume":"32","author":"Vizca\u00edno","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0195","doi-asserted-by":"crossref","first-page":"2278","DOI":"10.1021\/pr901027r","article-title":"Analysis of the ontogenetic variation in the venom proteome\/peptidome of Bothrops jararaca reveals different strategies to deal with prey","volume":"9","author":"Zelanis","year":"2010","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0200","doi-asserted-by":"crossref","first-page":"169","DOI":"10.3109\/15569543.2014.922581","article-title":"The proteinase-rich proteome of Bothrops jararaca venom","volume":"33","author":"Serrano","year":"2014","journal-title":"Toxin Rev."},{"key":"10.1016\/j.bbapap.2021.140643_bb0205","doi-asserted-by":"crossref","first-page":"3752","DOI":"10.1021\/acs.jproteome.6b00561","article-title":"Dynamic rearrangement in snake venom gland proteome: insights into Bothrops jararaca intraspecific venom variation","volume":"15","author":"Augusto-De-Oliveira","year":"2016","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0210","doi-asserted-by":"crossref","first-page":"4561","DOI":"10.1073\/pnas.0914495107","article-title":"Sampling the N-terminal proteome of human blood","volume":"107","author":"Wildes","year":"2010","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.bbapap.2021.140643_bb0215","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/j.toxicon.2008.02.019","article-title":"High throughput screening of bradykinin-potentiating peptides in Bothrops moojeni snake venom using precursor ion mass spectrometry","volume":"51","author":"Menin","year":"2008","journal-title":"Toxicon."},{"key":"10.1016\/j.bbapap.2021.140643_bb0220","first-page":"2834","article-title":"Species delimitation with abc and other coalescent-based methods: a test of accuracy with simulations and an empirical example with lizards of the liolaemus darwinii complex (Squamata: Liolaemidae)","volume":"66","author":"Camargo","year":"2012","journal-title":"Evolution (N. Y)."},{"key":"10.1016\/j.bbapap.2021.140643_bb0225","doi-asserted-by":"crossref","DOI":"10.3390\/toxins10110474","article-title":"Snake venom peptides: Tools of biodiscovery","volume":"10","author":"Munawar","year":"2018","journal-title":"Toxins (Basel)"},{"key":"10.1016\/j.bbapap.2021.140643_bb0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.cbpa.2012.11.025","article-title":"Protein TAILS: when termini tell tales of proteolysis and function","author":"Lange","year":"2013","journal-title":"Curr. Opin. Chem. Biol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0235","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1001869","article-title":"Network analyses reveal pervasive functional regulation between proteases in the human protease web","volume":"12","author":"Fortelny","year":"2014","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0240","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1016\/j.jprot.2016.06.029","article-title":"An in-depth snake venom proteopeptidome characterization: benchmarking Bothrops jararaca","volume":"151","author":"Nicolau","year":"2017","journal-title":"J. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0245","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/S0006-291X(67)80055-X","article-title":"On the size of the active site in proteases. I. Papain","volume":"27","author":"Schechter","year":"1967","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbapap.2021.140643_bb0250","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1038\/nmeth1109-786","article-title":"Improved visualization of protein consensus sequences by iceLogo","volume":"6","author":"Colaert","year":"2009","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bbapap.2021.140643_bb0255","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jprot.2010.12.002","article-title":"High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry","volume":"74","author":"Paes Leme","year":"2011","journal-title":"J. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0260","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1007\/s00726-016-2218-z","article-title":"Proteome-derived peptide library for the elucidation of the cleavage specificity of HF3, a snake venom metalloproteinase","volume":"48","author":"Bertholim","year":"2016","journal-title":"Amino Acids"},{"key":"10.1016\/j.bbapap.2021.140643_bb0265","doi-asserted-by":"crossref","first-page":"3419","DOI":"10.1021\/acs.jproteome.9b00325","volume":"18","author":"Zelanis","year":"2019","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.bbapap.2021.140643_bb0270","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.jprot.2014.10.002","article-title":"Snake venom serine proteinases specificity mapping by proteomic identification of cleavage sites","volume":"113","author":"Zelanis","year":"2015","journal-title":"J. Proteomics"},{"key":"10.1016\/j.bbapap.2021.140643_bb0275","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.1111\/j.1365-294X.2006.03057.x","article-title":"Phylogeography of the Bothrops jararaca complex (Serpentes: Viperidae): past fragmentation and island colonization in the Brazilian Atlantic Forest","volume":"15","author":"Grazziotin","year":"2006","journal-title":"Mol. Ecol."},{"key":"10.1016\/j.bbapap.2021.140643_bb0280","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/j.bbrc.2004.08.012","article-title":"Activation of \u03b1 M\u03b2 2-mediated phagocytosis by HF3, a P-III class metalloproteinase isolated from the venom of Bothrops jararaca","volume":"322","author":"Silva","year":"2004","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bbapap.2021.140643_bb0285","series-title":"Anim. Toxins State Art. Perspect. Heal. Biothecnology","first-page":"525","article-title":"Snake venom metalloproteinases. Structure, function and effects on snake bite pathology","author":"Moura-da-Silva","year":"2009"},{"key":"10.1016\/j.bbapap.2021.140643_bb0290","doi-asserted-by":"crossref","first-page":"2388","DOI":"10.1038\/sj.emboj.7601131","article-title":"Crystal structures of VAP1 reveal ADAMs\u2019 MDC domain architecture and its unique C-shaped scaffold","volume":"25","author":"Takeda","year":"2006","journal-title":"EMBO J."},{"key":"10.1016\/j.bbapap.2021.140643_bb0295","doi-asserted-by":"crossref","first-page":"2401","DOI":"10.1126\/science.1078376","article-title":"Coordinated nonvectorial folding in a newly synthesized multidomain protein","volume":"298","author":"Jansens","year":"2002","journal-title":"Science (80-. )"},{"key":"10.1016\/j.bbapap.2021.140643_bb0300","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.tibs.2017.10.006","article-title":"How are proteins reduced in the endoplasmic reticulum?","volume":"43","author":"Ellgaard","year":"2018","journal-title":"Trends Biochem. Sci."}],"container-title":["Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570963921000492?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1570963921000492?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T21:23:16Z","timestamp":1778620996000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1570963921000492"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":60,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2021,7]]}},"alternative-id":["S1570963921000492"],"URL":"https:\/\/doi.org\/10.1016\/j.bbapap.2021.140643","relation":{},"ISSN":["1570-9639"],"issn-type":[{"value":"1570-9639","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The distinct N-terminomes of Bothrops jararaca newborn and adult venoms","name":"articletitle","label":"Article Title"},{"value":"Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bbapap.2021.140643","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"140643"}}