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A."},{"issue":"2","key":"10.1016\/j.bbcan.2022.188705_bb0590","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1016\/j.cmet.2015.06.023","article-title":"Hypoxia induces production of L-2-hydroxyglutarate","volume":"22","author":"Intlekofer","year":"2015","journal-title":"Cell Metab."},{"issue":"7390","key":"10.1016\/j.bbcan.2022.188705_bb0595","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1038\/nature10898","article-title":"Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation","volume":"483","author":"Koivunen","year":"2012","journal-title":"Nature"},{"issue":"7390","key":"10.1016\/j.bbcan.2022.188705_bb0600","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1038\/nature10860","article-title":"IDH mutation impairs histone demethylation and results in a block to cell differentiation","volume":"483","author":"Lu","year":"2012","journal-title":"Nature"},{"issue":"6","key":"10.1016\/j.bbcan.2022.188705_bb0605","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1016\/j.ccr.2010.11.015","article-title":"Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation","volume":"18","author":"Figueroa","year":"2010","journal-title":"Cancer Cell"},{"issue":"4","key":"10.1016\/j.bbcan.2022.188705_bb0610","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.tcb.2008.01.006","article-title":"Mitochondria in cancer cells: what is so special about them?","volume":"18","author":"Gogvadze","year":"2008","journal-title":"Trends Cell Biol."},{"issue":"8","key":"10.1016\/j.bbcan.2022.188705_bb0615","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1038\/sj.cdd.4401963","article-title":"Mitochondrial outer membrane permeabilization during apoptosis: the innocent bystander scenario","volume":"13","author":"Chipuk","year":"2006","journal-title":"Cell Death Differ."},{"issue":"6","key":"10.1016\/j.bbcan.2022.188705_bb0620","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.ceb.2006.10.004","article-title":"How do Bax and Bak lead to permeabilization of the outer mitochondrial membrane?","volume":"18","author":"Antignani","year":"2006","journal-title":"Curr. 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(Baltimore, Md. : 1950)"},{"issue":"5938","key":"10.1016\/j.bbcan.2022.188705_bb0825","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1126\/science.1172308","article-title":"RIP3, an energy metabolism regulator that switches TNF-induced cell death from apoptosis to necrosis","volume":"325","author":"Zhang","year":"2009","journal-title":"Science"},{"issue":"2","key":"10.1016\/j.bbcan.2022.188705_bb0830","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1038\/s41556-017-0022-y","article-title":"RIP3 targets pyruvate dehydrogenase complex to increase aerobic respiration in TNF-induced necroptosis","volume":"20","author":"Yang","year":"2018","journal-title":"Nat. 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A."},{"issue":"2","key":"10.1016\/j.bbcan.2022.188705_bb0875","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.molcel.2018.10.042","article-title":"Role of mitochondria in ferroptosis","volume":"73","author":"Gao","year":"2019","journal-title":"Mol. 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Des."},{"issue":"4","key":"10.1016\/j.bbcan.2022.188705_bb1220","doi-asserted-by":"crossref","first-page":"6742","DOI":"10.18632\/oncotarget.14272","article-title":"CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming","volume":"8","author":"Kendrick","year":"2017","journal-title":"Oncotarget"},{"issue":"9","key":"10.1016\/j.bbcan.2022.188705_bb1225","doi-asserted-by":"crossref","first-page":"4182","DOI":"10.1158\/0008-5472.CAN-06-3184","article-title":"Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231","volume":"67","author":"Gallagher","year":"2007","journal-title":"Cancer Res."},{"issue":"1","key":"10.1016\/j.bbcan.2022.188705_bb1230","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1016\/j.bbrc.2008.06.122","article-title":"Blocking CD147 induces cell death in cancer cells through impairment of glycolytic energy metabolism","volume":"374","author":"Baba","year":"2008","journal-title":"Biochem. 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Biol. Chem."},{"issue":"8","key":"10.1016\/j.bbcan.2022.188705_bb1405","doi-asserted-by":"crossref","first-page":"9429","DOI":"10.18632\/oncotarget.6990","article-title":"A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells","volume":"7","author":"Fu","year":"2016","journal-title":"Oncotarget"},{"issue":"5","key":"10.1016\/j.bbcan.2022.188705_bb1410","doi-asserted-by":"crossref","first-page":"973","DOI":"10.3324\/haematol.2018.199661","article-title":"The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells","volume":"104","author":"Spinello","year":"2019","journal-title":"Haematologica"},{"issue":"5","key":"10.1016\/j.bbcan.2022.188705_bb1415","doi-asserted-by":"crossref","first-page":"4422","DOI":"10.1021\/acsabm.1c00177","article-title":"CD147 monoclonal antibody targeted reduction-responsive camptothecin polyphosphoester nanomedicine for drug delivery in hepatocellular carcinoma Cells","volume":"4","author":"Tian","year":"2021","journal-title":"ACS Appl. 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Int."},{"issue":"4","key":"10.1016\/j.bbcan.2022.188705_bb1545","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.18203\/2349-2902.isj20201396","article-title":"Cell cannibalism: a diagnostic and prognostic marker of breast cancer","volume":"7","author":"Mohsin","year":"2020","journal-title":"Int. Surg. J."},{"issue":"18","key":"10.1016\/j.bbcan.2022.188705_bb1550","doi-asserted-by":"crossref","first-page":"5548","DOI":"10.3748\/wjg.v21.i18.5548","article-title":"Phagocytosis (cannibalism) of apoptotic neutrophils by tumor cells in gastric micropapillary carcinomas","volume":"21","author":"Barresi","year":"2015","journal-title":"World J Gastroenterol: WJG"},{"issue":"5","key":"10.1016\/j.bbcan.2022.188705_bb1555","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1111\/j.1365-2303.2006.00326.x","article-title":"Cell cannibalism in ductal carcinoma of breast","volume":"17","author":"Abodief","year":"2006","journal-title":"Cytopathol. Off. J. Br. Soc. Clin. 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Sci."},{"key":"10.1016\/j.bbcan.2022.188705_bb1565","doi-asserted-by":"crossref","first-page":"S90","DOI":"10.1016\/j.oraloncology.2013.03.240","article-title":"OP231: Identification of cell cannibalism in oral squamous cell carcinoma with clinico-pathological correlation","volume":"49","author":"Sarode","year":"2013","journal-title":"Oral Oncol."},{"key":"10.1016\/j.bbcan.2022.188705_bb1570","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.22187","article-title":"Horizontal transfer of whole mitochondria restores tumorigenic potential in mitochondrial DNA-deficient cancer cells","volume":"6","author":"Dong","year":"2017","journal-title":"eLife"},{"issue":"27","key":"10.1016\/j.bbcan.2022.188705_bb1575","doi-asserted-by":"crossref","first-page":"5339","DOI":"10.1038\/s41388-019-0805-7","article-title":"Cancer-associated fibroblasts promote prostate cancer malignancy via metabolic rewiring and mitochondrial transfer","volume":"38","author":"Ippolito","year":"2019","journal-title":"Oncogene"},{"issue":"5","key":"10.1016\/j.bbcan.2022.188705_bb1580","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1073\/pnas.0510511103","article-title":"Mitochondrial transfer between cells can rescue aerobic respiration","volume":"103","author":"Spees","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.bbcan.2022.188705_bb1585","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.cmet.2014.12.003","article-title":"Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA","volume":"21","author":"Tan","year":"2015","journal-title":"Cell Metab."},{"issue":"2","key":"10.1016\/j.bbcan.2022.188705_bb1590","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/j.cmet.2018.10.014","article-title":"Reactivation of dihydroorotate dehydrogenase-driven pyrimidine biosynthesis restores tumor growth of respiration-deficient cancer cells","volume":"29","author":"Bajzikova","year":"2019","journal-title":"Cell Metab."},{"issue":"3","key":"10.1016\/j.bbcan.2022.188705_bb1595","doi-asserted-by":"crossref","first-page":"e32778","DOI":"10.1371\/journal.pone.0032778","article-title":"Mesenchymal stem cells transfer mitochondria to the cells with virtually no mitochondrial function but not with pathogenic mtDNA mutations","volume":"7","author":"Cho","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.bbcan.2022.188705_bb1600","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1158\/0008-5472.CAN-18-0773","article-title":"CD38-driven mitochondrial trafficking promotes bioenergetic plasticity in multiple myeloma","volume":"79","author":"Marlein","year":"2019","journal-title":"Cancer Res."},{"issue":"14","key":"10.1016\/j.bbcan.2022.188705_bb1605","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1182\/blood-2017-03-772939","article-title":"NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts","volume":"130","author":"Marlein","year":"2017","journal-title":"Blood"},{"issue":"1","key":"10.1016\/j.bbcan.2022.188705_bb1610","article-title":"Tunneling nanotubes","volume":"7","author":"Austefjord","year":"2014","journal-title":"Commun Integrat. 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